Images d’un camp de vacances en pays socialiste by Ania Szczepanska

“…Pour cela, il élabore un protocole de travail singulier : aux vacanciers s’ajoutent des personnes complices du cinéaste dont le rôle sera pour certains de participer activement à la vie collective, pour d’autres de s’y opposer.Tourné en 1976, le documentaire Comment vivre attendra cinq années avant d’être diffusé en salle, en tant que fiction. …”
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An updated overview of Juvenile systemic sclerosis in a French cohort by Léa Jacquel, Rouba Bechara, Joëlle Terzic, Anne-Cécile Rameau, Emmanuel Chatelus, Linda Rossi-Semerano, Isabelle Kone-Paut, Ulrich Meinzer, Irène Lemelle, Charlotte Rebelle, Diego Urbina, Pascal Pillet, Pauline Choquet, Jad El Maamari, Ariane Zaloszyc, SOFREMIP

“…Three patients received treatment with biological agents, specifically Rituximab and Tocilizumab. Conclusion JSSc is a rare but severe disease requiring rapid, specialized, and multidisciplinary care. …”
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Violência ocupacional, processo laboral e saúde mental de profissionais da saúde by Fernanda Beatriz Melo Maciel, Maria Gabrielle Lopes Cordeiro, Luana Leal Gonzaga, Gabriela Garcia de Carvalho Laguna, Hebert Luan Pereira Campos dos Santos, Luiz Henrique Pitanga Evangelista, Nília Maria de Brito Lima Prado

“…Resultados: Da análise, emergiram categorias relacionadas à violência ocupacional sofrida por profissionais da saúde: formas de violência descritas; agentes que perpetram a violência; profissionais que sofreram a violência; implicações da violência sobre saúde mental e laboral; e as respostas institucionais e legais frente à ocorrência da violência ocupacional. …”
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Impact of garlic polysulfide supplementation on biochemical and hematological parameters in dairy cows by Nedić Sreten, Gajić Mirjana, Bošnjaković Dušan, Vujanac Ivan, Prodanović Radiša, Bojkovski Jovan, Mitrović Aleksandra, Milenković Milan, Manojlović Dragan, Jovanović Ljubomir, Kirovski Danijela, Arsić Sveta

“…In recent years, there have been numerous research activities related to the use of different herbal agents, especially those originating from chestnuts and garlic, as alternatives to synthetic growth promoters like antibiotics. …”
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Anti-Apoptosis Effects of Green Tea in Diagnostic and Therapeutic Doses of Ionizing Radiation by Najmeh Anbiaee, Mohammad Taghi Bahreyni Toossi, Hosein Azimian, Zoha Sahebnasagh, Sepideh Abdollahi Dehkordi, Majid Kianmehr, samaneh soudmand salarabadi, Maryam Najafi Amiri

“…Introduction: Patients who receive ionizing radiation for diagnosis or treatment may suffer side effects in normal tissues. Radioprotective agents have the potential to decrease DNA damage and free radicals produced by ionizing radiation. …”
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Effects of Biostabilization on Engineering Properties of Geomaterials by Shengting Li, Chenyi Luo, Yi Yang, Lvzhen Yang, Lijian Wu, Tuo Huang, Zhuangji Wang

“…EDS and XRD results indicated that calcite, dolomite, and albite were the major precipitates produced during biostabilization treatments. …”
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Assessment of cardio-oncology knowledge and practice among healthcare providers in Saudi Arabia: a comprehensive nationwide survey by Hisham A. Badreldin, Nada Alsuhebany, Lama Alfehaid, Mohammed Alzahrani, Maha Aldoughaim, Abdullah M. Alrajhi, Jumanah Alsufyani, Dania Elsherif, Kanan Alshammari

“…Despite agreement on the need for cardiotoxicity management, only one-third recommended cardioprotective agents as standard care. Conclusion There is a notable deficiency in formal training and resources for cardio-oncology in Saudi Arabia. …”
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Enhanced UV-B photoprotection activity of carotenoids from the novel Arthrobacter sp. strain LAPM80 isolated from King George Island, Antarctica by Beatriz Vivian Paredes Contreras, Alane Beatriz Vermelho, Livia Casanova, Claudia de Alencar Santos Lage, Caren Leite Spindola Vilela, Veronica da Silva Cardoso, Luis William Pacheco Arge, Janine Simas Cardoso-Rurr, Sulamita Santos Correa, Felipe Raposo Passos De Mansoldo, Maria Cristina Pinheiro Pereira Reis-Mansur, Eikon Alves da Silva, Júnia Schultz, Alexandre Soares Rosado

“…Also, there is a growing demand for natural and environmentally friendly photoprotectors, such as microbial-based products, in opposition to synthetic photoprotective agents with known adverse effects.In this study, we assessed the carotenoid-producing abilities of Actinomycetota strains from Antarctic Peninsula soils and the photoprotective carotenoid action on UV irradiation resistance. …”
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In Vivo Magic Angle Magnetic Resonance Imaging for Cell Tracking in Equine Low-Field MRI by Carolin Horstmeier, Annette B. Ahrberg, Dagmar Berner, Janina Burk, Claudia Gittel, Aline Hillmann, Julia Offhaus, Walter Brehm

“…Furthermore, it could support the discrimination of hypointense artefacts induced by contrast agents such as superparamagnetic iron oxide used for cell tracking. …”
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Mesenchymal stem cell-derived extracellular vesicles enriched with miR-124 exhibit anti-inflammatory effects in collagen-induced arthritis by Guo Zhonghua, He Mengyuan, Shi Dongliang, Zhang Zhongbo, Wang Lisha, Ren Bowen, Wang Yunfei, Wang Junjie, Yang Shaoxiang, Yu Hongchao

“…Mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) hold significant promise as therapeutic agents owing to their potent paracrine activities. …”
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Inferior Outcomes of Fludarabine–Cyclophosphamide–Rituximab Chemotherapy in Korean Chronic Lymphocytic Leukemia Patients with Concurrent Thrombocytopenia and Anemia by Tong-Yoon Kim, Gi-June Min, Young-Woo Jeon, Seung-Ah Yahng, Seok-Goo Cho, Jong-Mi Lee, Myungshin Kim, Ki-Seong Eom

“…In the Republic of Korea, where insurance limits coverage to novel agents, FCR therapy should be carefully considered for patients with CLL. …”
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Neuroprotective Effect of Melatonin Loaded in Human Serum Albumin Nanoparticles Applied Subconjunctivally in a Retinal Degeneration Animal Model by Sofia Mickaela Martinez, Ayelen Inda, Maximiliano Nicolás Ríos, Carolina del Valle Bessone, Abril Bruera Bossio, Mario Eduardo Guido, José Domingo Luna Pinto, Daniel Alberto Allemandi, Daniela Alejandra Quinteros

“…Methods: A model of retinal degeneration was induced in New Zealand albino rabbits using cytotoxic and oxidative agents. Np-HSA-Mel nanoparticles were administered subconjunctivally, and cellular viability and retinal functionality were assessed using flow cytometry and pupillary light reflex (PLR). …”
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Survey of parasitic fauna data from wild animals through coproparasitological diagnosis in Southern Brazil by Julia Somavilla Lignon, Diego Moscarelli Pinto, Tamires Silva dos Santos, Giulia Ribeiro Meireles, Camila Gonçalves da Silveira, Bianca Conrad Bohm, Felipe Geraldo Pappen, Silvia Gonzalez Monteiro, Mauro Pereira Soares, Raqueli Teresinha França, Fábio Raphael Pascoti Bruhn

“…Additionally, 64.9% of the positive samples were parasitized by at least one morphogroup with zoonotic agents (Taeniidae, Capillaria, Strongyloides, Spirometra, Lagochilascaris, Sarcocystis, Trichuris, Giardia, Ancilostomid, Physaloptera, Toxocara, Fasciola). …”
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Integrative pan-cancer analysis and experiment validation identified GLS as a biomarker in tumor progression, prognosis, immune microenvironment, and immunotherapy by Dongming Li, Donghui Cao, Yangyu Zhang, Xinyi Yu, Yanhua Wu, Zhifang Jia, Jing Jiang, Xueyuan Cao

“…Meanwhile, we noticed GLS expression was strongly related to the infiltration of various immune cells and stromal cells, the expression of immunomodulatory genes, the activity of some conventional antitumor agents, and the therapeutic response of immunotherapy. …”
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Apelinergic System Affects Electrocardiographic Abnormalities Induced by Doxorubicin by Kasper Buczma, Hubert Borzuta, Katarzyna Kamińska, Dorota Sztechman, Katarzyna Matusik, Jan Pawlonka, Michał Kowara, Barbara Buchalska, Agnieszka Cudnoch-Jędrzejewska

“…<b>Conclusions</b>: Our findings support the use of apelin and elabela as potential cardioprotective agents against anthracycline-induced cardiotoxicity.…”
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From canonical to unique: extension of a lipophilicity scale of amino acids to non-standard residues by Antonio Viayna, Paulina Matamoros, David Blázquez-Ruano, William J. Zamora

“…Aim: The lipophilicity of amino acids plays a crucial role in delineating their physicochemical properties, offering insights into solubility, binding affinity, and bioavailability, properties that are a cornerstone for the use of peptides as therapeutic agents. In this study, we employ the integral equation formalism polarizable continuum model/Miertus-Scrocco-Tomasi (IEFPCM/MST) implicit solvation model to compute the n-octanol/water partition coefficient, serving as a lipophilic descriptor for non-standard amino acids. …”
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Synthesis of Amino Acid Schiff Base Nickel (II) Complexes as Potential Anticancer Drugs In Vitro by Yang Li, Jianfang Dong, Peiran Zhao, Ping Hu, Dawei Yang, Lei Gao, Lianzhi Li

“…Three hexacoordinated octahedral nickel (II) complexes, [Ni (Trp-sal) (phen) (CH3OH)] (1), [Ni (Trp-o-van) (phen) (CH3OH)]•2CH3OH (2), and [Ni (Trp-naph) (phen) (CH3OH)] (3) (where Trp-sal = Schiff base derived from tryptophan and salicylaldehyde, Trp-o-van = Schiff base derived from tryptophan and o-vanillin, Trp-naph = Schiff base derived from tryptophan and 2-hydroxy-1-naphthaldehyde, phen = 1, 10-phenanthroline), have been synthesized and characterized as potential anticancer agents. Details of structural study of these complexes using single-crystal X-ray crystallography showed that distorted octahedral environment around nickel (II) ion has been satisfied by three nitrogen atoms and three oxygen atoms. …”
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Anti-VEGF therapy improves EGFR-vIII-CAR-T cell delivery and efficacy in syngeneic glioblastoma models in mice by Dai Fukumura, Rakesh K Jain, Jun Ren, Xinyue Dong, Zohreh Amoozgar, Somin Lee, Meenal Datta, Sylvie Roberge, Mark Duquette

“…Our findings provide compelling data and a rationale for clinical evaluation of anti-VEGF agents with CAR T cells for GBM patients.…”
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Phages adapt to recognize an O-antigen polysaccharide site by mutating the “backup” tail protein ORF59, enabling reinfection of phage-resistant Klebsiella pneumoniae by Ping Li, Wenjie Ma, Jun Cheng, Cuixing Zhan, Hongzhou Lu, Jiayin Shen, Xin Zhou

“…Phages demonstrate remarkable promise as antimicrobial agents against antibiotic-resistant bacteria. However, the emergence of phage-resistant strains poses challenges to their effective application. …”
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Dual inhibition of BET and EP300 has antitumor activity in undifferentiated pleomorphic sarcomas and synergizes with ferroptosis induction by Stéphanie Verbeke, Aurélien Bourdon, Mathilde Lafon, Vanessa Chaire, Bertolo Frederic, Amina Naït Eldjoudi, Marie-Alix Derieppe, Francis Giles, Antoine Italiano

“…Epigenetic modifiers has been extensively investigated in recent years leading to the development of novel therapeutic agents. Dual BET/EP300 inhibitors have shown synergistic antitumor activity and have recently entered clinical development. …”
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