Petites mains féminines, vulnérabilité professionnelle et pratiques conjointes de compensation financières dans l’administration publique universitaire au Cameroun by Prisca Hélène Assiene Bissossoli

“…De ce fait, situées à des positions d’infériorité administratives, les petites mains féminines, contractuelles temporaires d’administration ou à statut par défaut, semblent plus exposées aux pressions résultant des différents aléas sociopolitique, sanitaire, économique et de gestion auxquels peut être confrontée l’institution universitaire. …”
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EGFR-targeting RNase A-cetuximab antibody-drug conjugate induces ROS-mediated apoptosis to overcome drug resistance in KRAS mutant cancer cells by Bita Jafary, Mostafa Akbarzadeh-Khiavi, Hamed Farzi-Khajeh, Azam Safary, Khosro Adibkia

“…Abstract Antibody-drug conjugates (ADCs) are an emerging strategy in cancer therapy, enhancing precision and efficacy by linking targeted antibodies to potent cytotoxic agents. This study introduces a novel ADC that combines ribonuclease A (RNase A) with cetuximab (Cet), an anti-EGFR monoclonal antibody, through a polyethylene glycol (PEG) linker (RN-PEG-Cet), aimed to induce apoptosis in KRAS mutant colorectal cancer (CRC) via a ROS-mediated pathway. …”
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Efectos del incremento de la erosividad de lluvia en la estimación de pérdida de suelo (RUSLE) en el periodo 1997-2018: comparación en dos cuencas mediterráneas con diferentes con... by José Antonio Sillero Medina, Juan Francisco Martínez Murillo, José Damián Ruiz Sinoga

“…Así, es necesario avanzar en la estimación de la pérdida de suelo por erosión hídrica, principal agente geomorfológico en dicha zona. Este estudio aplica la ecuación RUSLE en dos cuencas de media montaña, con diferentes condiciones pluviométricas, durante el periodo 1997-2018; ambas cuencas presentan rasgos ecogeomorfológicos propios de la montaña mediterránea. …”
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Characteristics of COVID-19 clinical trials registered with ClinicalTrials.gov: cross-sectional analysis by Timothy F Platts-Mills, Christopher W Jones, Ashley L Woodford

“…Objectives To characterise current COVID-19-related research activities.Design Cross-sectional analysis.Setting Clinical trials registered with ClinicalTrials.gov testing interventions relevant to COVID-19.Data sources ClinicalTrials.gov was searched for COVID-19 and related terms to identify trials registered between 1 December 2019 and 1 May 2020 that test interventions related to the COVID-19 pandemic.Main outcome measures We classified trials according to intervention type, and report key trial characteristics including recruitment status, location, funder type, target enrolment number, intervention model (single group, randomised or sequential assignment) and projected completion date.Results Of the 630 identified clinical trials related to COVID-19, 509 (81%) involved the study of drugs or biological agents. Of these trials of drugs and biologics, 305 (60%) use an open-label design, 43 (8%) are single blinded (participant only) and 161 (32%) are double blinded (participant and investigator). 94 (18%) of the drug/biological trials are non-randomised. …”
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Evaluación de la calidad de subproductos de la soja by I. SEIJAS NOYA, G. JAURENA, M. WAWRZKIEWICZ, M. GAGGIOTTI, L.A. ROMERO, M. MÉNDEZ

“…Entre los factores del procesamiento industrial que modificaron la variabilidad del expeller se encontró que la limpieza del grano previo a la extracción del aceite aumentó el contenido de EE del poroto y disminuyó el del expeller, incrementando un 22% la eficiencia de extracción. …”
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Syntheses, Characterization, and Antimicrobial Screening of N-(benzothiazol-2-yl)benzenesulphonamide and its Cu(I), Ni(II), Mn(II), Co(II), and Zn(II) Complexes by N. L. Obasi, Okoye C. O. Benedict, P. O. Ukoha, A. O. Anaga

“…The antimicrobial activities of the compounds were compared with those of Ciprofloxacin and trimethoprim-sulphamethoxazole as antibacterial agents and Fluconazole as an antifungal drug. All the compounds showed varying activities against the cultured typed bacteria and fungi used. …”
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In vivo antidiabetic and ex-vivo antioxidant activities of dichloromethane extract of Xerophyta spekei by Michael Musila Ndile, Wycliffe Arika Makori, Cromwell Mwiti Kibiti, Mathew Piero Ngugi

“…The medicinal plant also serves as a potential source for developing antidiabetic agents.…”
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APLASTIC SYNDROME IN A PREGNANT WOMAN ON THE BACKGROUND OF COVID-19: A CLINICAL CASE by Индира Венеровна Сахаутдинова, Ирина Борисовна Фаткуллина, Ирина Робинзоновна Рахматуллина, Игорь Сергеевич Засядкин, Анна Юрьевна Лазарева

“…Physiological changes are also known in other systems, for example, respiratory, digestive, urinary and cardiovascular, which suggest vulnerability to the influence of pathological agents and the formation of severe infection, which can lead to an increase in maternal morbidity and mortality. …”
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DETECCIÓN DEL GENOMA DEL VIRUS DE LA HEPATITIS E (VHE) EN MUESTRAS DE HECES DE CERDOS EN PLANTAS DE BENEFICIO DE ANTIOQUIA, COLOMBIA by J. E. Forero, J. E. Parra, A. López

“…El Virus de la Hepatitis E (VHE) es uno de los agentes causales de enfermedad hepáticaaguda en humanos, aunque también puede inducir hepatitis crónica en pacientes in-munocomprometidos. …”
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Conditional knockdown of hepatic PCSK9 ameliorates high-fat diet-induced liver inflammation in mice by Xue-Ying Zhang, Qing-Qing Lu, Yan-Jie Li, Shan-Rui Shi, Chao-Nan Ma, Miao Miao, Shou-Dong Guo

“…These findings confirmed that conditional knockdown of hepatic PCSK9 attenuates liver inflammation following hyperlipidemia induction by modulating multiple signaling pathways; this suggests that targeting PCSK9 knockdown/inhibition with appropriate agents is useful not only for treating hyperlipidemia but also for ameliorating hyperlipidemia-induced liver inflammation.…”
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Reflexiones sobre el proyecto Auto-Demarcación y EtnoCartografía de las Tierras y Hábitats Jodï y Eñepa by Stanford Zent, Egleé L. Zent, Lucas Juae Mölö, Pablo Chonokó

“…In the second place, we analyze the ambiguity of the State in regards to Indian land rights recognition throughout the Bolivarian constitutional period, as reflected in various contradictions between written laws and legal practices, the separate actions and attitudes of different government agents at regional and national levels, the inconsistencies in the institutional authorities and application of norms established to promote the demarcation process, the legal lacunae or recurrent changes in the rules regarding the petition of land rights recognition, among other aspects that have impeded reaching the final goal of indigenous land demarcations: obtaining legal title or ownership rights over their lands. …”
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Breaking the shield of solid tumors: a combined approach for enhanced efficacy of CAR-T cells by Marat Khaliulin, Aygul Valiullina, Alexey Petukhov, Youyong Yuan, Sheila Spada, Emil Bulatov

“…This review examines the principal obstacles to the utilization of CAR-T cells against solid tumors, proposes solutions to these issues, and assesses the potential advantages of a combined approach to radiation exposure, which has the potential to enhance the sensitivity of the tumor to other agents.…”
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Formação de professores em CALL para o ensino de língua inglesa: o uso de objetos digitais by Laysa Cristina de Oliveira, Patrícia Vasconcelos Almeida

“…Após análise dos estudos selecionados compreende-se que é fundamental que os educadores adquiram competências digitais por meio de formação continuada, tornando-se agentes de transformação na educação, promovendo uma abordagem criativa e inovadora no uso das TDs para uma educação de qualidade na era digital. …”
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Caracterización clínica y epidemiológica de fallecidos con diagnóstico necrópsico de endocarditis infecciosa 1986-2008 by Miguel Ángel Serra Valdés, Ezequiel López Espinosa, Alfredo Ferras Martínez, Gloria Fabra Aguirre

“…<strong>Fundamento</strong>: La endocarditis infecciosa se considera como una afección grave, debido a la agresividad del agente infeccioso que la causa, el daño valvular y la afectación multiorgánica que puede provocar. …”
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Assessing the quality of CKD care using process quality indicators: A scoping review. by Na Zhou, Chengchuan Chen, Yubei Liu, Zhaolan Yu, Aminu K Bello, Yanhua Chen, Ping Liu

“…The three categories included laboratory measures and monitoring of CKD progression and/or complications (monitoring of kidney markers, CKD mineral and bone disorder, anemia and malnutrition, electrolytes, and volume), use of guideline-recommended therapeutic agents (use of medications), and attainment of therapeutic targets (blood pressure, glycemia, and lipids). …”
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La capacitación y oportunidades para la creación de empresas competitivas by Yanary Emelina Carvallo Monsalve, Ariana Paola Herrera Pérez, Yanamir Coromoto Carvallo Monsalve

“…El instrumento aplicado, se elaboró utilizando la medición de Likert del 1 al 5, el cual se validó primeramente con el Alpha de Cronbach aplicando para ello una prueba piloto, obteniendo un valor de 0,97, el cual es considerado un valor aceptable para el tipo de investigación. Resultados: La capacitación recibida por las mujeres de la Fundación Ecuador Igualitario,  han generado la creación de habilidades y conocimientos en cuanto a la creación de emprendimientos y empresas competitivas. …”
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Una escultura de Juan José Sicre Vélez para honrar al doctor Carlos J. Finlay Barrés by Jorge Eduardo Abreu Ugarte

“…Finlay", en Marianao, tiene simbolismo por ser la localidad donde Finlay desarrolló la mayor parte de las investigaciones conducentes a su teoría sobre el modo de contagio y el agente transmisor de la fiebre amarilla. La obra escultórica es también un hermoso homenaje a los médicos y trabajadores de la salud que prestan servicios médicos humanitarios en Cuba y en otros países. …”
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Surgical site infections post-ventriculoperitoneal shunting: A matched healthcare cost and length of stay study: Empirical research quantitative by Issa M. Hweidi, Saba W. Al-Ibraheem, Omar H. Jebreel

“…Furthermore, Acinetobacter baumanii and Klebsiella pneumonia were identified as being the most predominant causative agents of SSIs. Conclusion: The results of this study provide baseline data for national and regional benchmarking to evaluate the quality of care provided to likewise patients. …”
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Succinate Supplement Elicited “Pseudohypoxia” Condition to Promote Proliferation, Migration, and Osteogenesis of Periodontal Ligament Cells by Huimin Mao, Andi Yang, Yunhe Zhao, Lang Lei, Houxuan Li

“…Most mesenchymal stem cells reside in a niche of low oxygen tension. Iron-chelating agents such as CoCl2 and deferoxamine have been utilized to mimic hypoxia and promote cell growth. …”
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Etiopathogenic theories of nervous system diseases in Vilnius in the early 19th century: “insanity and epilepsy exacerbate when the moonlight shines” by E. Sakalauskaitė-Juodeikienė

“…It was also stated that some NS diseases may be triggered by physical and mechanical causes, concomitant diseases, medications and drinks, strong emotions, or violation of sleep hygiene. “Inflammatory agents” were reported to cause traumatic tetanus as inflammation spread upwards from the nerve endings, tendons, and ligaments to the brain. …”
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