Comparison of Tumor Non-specific and PD-L1 Specific Imaging by Near-Infrared Fluorescence/Cerenkov Luminescence Dual-Modality In-situ Imaging by Linhan Zhang MD, Lianmeng Zhao MS, Xue Lin MD, Sheng Zhao MD, Wenbin Pan MS, Dandan Wang MD, Zhongqi Sun MD, Jinping Li MD, Zonghui Liang MD, Rongjun Zhang MS, Huijie Jiang MD

“…Background Labeled antibodies are excellent imaging agents in oncology to non-invasively visualize cancer-related antigens expression levels. …”
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Resolution dependence of vessel size index across various brain regions by DongKyu Lee, Yelim Gong, Abel Worku Tessema, SoHyun Han, Hyung Joon Cho

“…Absolute VSI estimation, often utilizing superparamagnetic iron oxide nanoparticles as contrast agents, relies on measuring transverse relaxation rates (∆R2⁎ and ∆R2). …”
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lncRNA PANTR1 Upregulates BCL2A1 Expression to Promote Tumorigenesis and Warburg Effect of Hepatocellular Carcinoma through Restraining miR-587 by Xirui Ma, Ziming Mao, Jing Zhu, Huifang Liu, Fengling Chen

“…Finding novel curative agents for HCC is urgently needed. In the current study, we hypothesized that lncRNA PANTR1 participates in HCC initiation or progression. …”
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Rationale and Design of a Randomized, Open‐Label, Parallel‐Group Study of Esaxerenone Versus Angiotensin Receptor Blockers in Older Patients With Uncontrolled Hypertension on Calci... by Kazuomi Kario, Tomohiro Katsuya, Tatsuo Shimosawa, Takashi Taguchi, Ayumi Tanabe, Mitsuru Ohishi, the ESCORT‐HT investigators

“…This highlights the need for other antihypertensive agents to be used in combination with CCBs to replace ARBs for more effective blood pressure (BP) control. …”
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Hypertrophic cardiomyopathy: insights into pathophysiology and novel therapeutic strategies from clinical studies by Samuel Oluwadare Olalekan, Olalekan Olanrewaju Bakare, Patrick Godwin Okwute, Ifabunmi Oduyemi Osonuga, Muinat Moronke Adeyanju, Victoria Biola Edema

“…Recent advances in therapeutic strategies, including novel pharmacological agents like mavacamten and aficamten, were examined for their potential to help patients manage the disease and lead more accommodating lifestyles. …”
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Quando i letteratti italiani promuovono ad “eccezione” il teatro (Pirandello, i futuristi, Pasolini, Testori, Maraini) by Giorgio Taffon

“…In particolare è all’incirca nei due decenni 1915-1925 e 1965-1975 che alcune personalità provenienti dal mondo della letteratura, del libro, hanno saputo offrire nuove idee ad un sistema teatrale quasi immobile. …”
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Investigation of Antibiofilm Activities from Marine Sponges’ Crude Extract of Pulau Bidong, Terengganu, Malaysia by Gazali Mohamad, Nur Izzah Alissa Wan Rosli Wan, Sarah Mohd Zahidi Siti, Amira Jamaludin Nur, Bakar Kamariah, Saidin Jasnizat

“…The study suggests H. amboinensis is a promising source for new antibiofilm agents. It effectively inhibits biofilm formation without killing bacteria. …”
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Composite solid sand reinforcement grouting material preparation and diffusion characteristics of slurry-water replacement grouting by Xianxiang Zhu, Qi Zhang, Dongxiang Hu, Linhua Zhong, Zixu Li, Lei Jin

“…This eco-friendly material combines calcined coal gangue powder and fly ash as Material A with a chemical slurry of silica sol as Material B, enhanced with curing agents and catalysts. Utilizing the Box-Behnken design within the response surface methodology, the physical and chemical properties of the raw materials were thoroughly investigated. …”
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Trends for Diarrhea Morbidity in the Jasikan District of Ghana: Estimates from District Level Diarrhea Surveillance Data, 2012–2016 by John Tetteh, Wisdom Kwami Takramah, Martin Amogre Ayanore, Augustine Adoliba Ayanore, Elijah Bisung, Josiah Alamu

“…About 22% of childhood deaths in developing countries are attributable to diarrhea. …”
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Preparation of Cod Gelatin Antifreeze Peptides and Its Application of Frozen-Thawed Surimi by Jin ZHANG, Tao YUAN, Xiaomei SHA, Yuelun XU, Yating KUANG, Zizi HU

“…In conclusion, DcAFPs exhibited significant cryoprotective effects on surimi that subjected to repeated freeze-thaw cycles and outperformed commercial antifreeze agents.…”
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La modellazione microstrutturale di materiali a struttura eterogenea: princìpi ed applicazioni by Luca Collini

“…In questo lavoro sono illustrati i princìpi che sono alla base dell’approccio micromeccanico, come i concetti di multiscala, di distribuzione statistica delle fasi, di descrizione mediante volumi di riferimento e di omogeneizzazione e localizzazione, e, attraverso alcune applicazioni pratiche delle principali tecniche di modellazione, sono illustrati e discussi criticamente i risultati della ricerca effettuata su varie strutture di ghisa nodulare.…”
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Bedside cerebral microvascular imaging of patients with disorders of consciousness: a feasibility study by Qianqian Ge, Lijie Huang, Qiang Fu, Shuai Han, Rui Wang, Jianghong He, Changhui Li, Changhui Li, Jianwen Luo, Long Xu

“…Notably, uPDI demonstrates high sensitivity and imaging depth, revealing microvessels as small as 320 μm in diameter at 4 cm depth, and detecting blood flow signals up to 6 cm beneath the scalp.ConclusionThrough the decompressive cranial windows of DoC patients, we obtained cerebral microvascular images with significantly higher sensitivity without the need for contrast agents.SignificanceOur research provides a novel bedside cerebral microcirculation imaging method for patients with DoC, offering convenient neurofunctional assessment to improve the clinical management of DoC patients.…”
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Therapeutic Effect of Zataria Multiflora Essential Oil on Burn Wound Infected by Pseudomonas aeruginosa by Maryam Zare, Elahe Sattarinezhad, Ali Karimi Akhormeh, Maryam Motevasel, Marzieh Ashrafmansouri, Maral Mokhtari, Omid Koohi Hosseinabadi, Aida Iraji, Azar Purkhosrow

“…Due to the rapid increase in resistance to the currently used antimicrobial agents, finding new antibiotics is one of the research priorities. …”
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Epigenetic drug screening identifies enzyme inhibitors A-196 and TMP-269 as novel regulators of sprouting angiogenesis by M. Beter, H. H. Pulkkinen, T. Örd, A. Sormunen, L. Kilpeläinen, J. E. Dunford, M. U. Kaikkonen, E. Aavik, N. Laham-Karam, U. Oppermann, J. P. Laakkonen, S. Ylä-Herttuala

“…To address these limitations and improve the reproducibility of epigenetic drug screening, we redesigned a 3D in vitro fibrin bead assay to utilize immortalized human aortic endothelial cells (TeloHAECs) and screened a focused compound library with 105 agents. Compared to the established model using primary human umbilical vein endothelial cells, TeloHAECs needed a higher-density fibrin gel for optimal sprouting, successfully forming sprouts under both normoxic and hypoxic cell culture conditions. …”
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Clinical performance of real-time nanopore metagenomic sequencing for rapid identification of bacterial pathogens in cerebrospinal fluid: a pilot study by Yoon Hyun Sung, Yong Kuk Ju, Hak Jun Lee, Seung Min Park, Jin Woong Suh, Jeong Yeon Kim, Jang Wook Sohn, Young Kyung Yoon

“…Abstract This study aimed to evaluate the usefulness of amplicon-based real-time metagenomic sequencing applied to cerebrospinal fluid (CSF) for identifying the causative agents of bacterial meningitis. We conducted a 16S rRNA amplicon sequencing using a nanopore-based platform, alongside routine polymerase chain reaction (PCR) testing or bacterial culture, to compare its clinical performance in pathogen detection on CSF samples. …”
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Le concept de forme symbolique dans l’iconologie d’E. Panofsky by Audrey Rieber

“…En étudiant l’art comme forme symbolique, Cassirer veut élucider la spécificité de l’activité de l’esprit propre à ce domaine. …”
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Factors associated with Physical Activity Counseling by Health Workers Questionnaire: construction, validation and reliability by João Miguel de Souza Neto, Sanderson Soares da Silva, José Cazuza de Farias Júnior, Filipe Ferreira da Costa

“…In the third step, a pilot study was carried out with 20 professionals (doctors, nurses and community health agents) from the Joao Pessoa, Paraíba Family Health Strategy. …”
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L’AUTOBIOGRAFIA DI UN FORZATO: “IL BALLO DEI PESCICANI” DI ALDO POMINI: UNA PRIMA ANALISI LINGUISTICA by Sara Sorrentino

“…L’analisi del testo, linguisticamente ascrivibile alla tipologia delle narrazioni semicolte, si concentrerà su alcune eccezionalità come i contatti, soprattutto lessicali, con codici linguistici diversi dall’italiano, principalmente il francese; le peculiarità stilistiche e la particolare inclinazione ad elaborare descrizioni di stampo storico ed etnografico, sulla base dalla lunga permanenza dello scrivente in Sud America.   …”
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The therapeutic potential of vitamins A, C, and D in pancreatic cancer by Alban Piotrowsky, Markus Burkard, Hendrik Schmieder, Sascha Venturelli, Olga Renner, Luigi Marongiu

“…In addition, there is increasing evidence that vitamin A and vitamin D influence the tumor stroma, making the tumor tissue more accessible to other therapeutic agents.Based on these promising findings, there is a high urgency to investigate vitamins A, C, and D in a clinical context as a supplement to standard therapy in PDAC. …”
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A generative deep neural network for pan-digestive tract cancer survival analysis by Lekai Xu, Tianjun Lan, Yiqian Huang, Liansheng Wang, Junqi Lin, Xinpeng Song, Hui Tang, Haotian Cao, Hua Chai

“…The following drug analysis suggested Dasatinib and YM155 as potential therapeutic agents for improving the prognosis of patients in pan-DTC immunotherapy, thereby contributing to the enhancement of cancer patient survival. …”
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