Relationship between the Plasma Levels of Catecholamines and Return of Spontaneous Circulation in Patients with Out-of-Hospital Cardiac Arrest by Yumi Ichikawa, Yusuke Sawada, Jun Nakajima, Yuta Isshiki, Kazunori Fukushima, Yuto Aramaki, Kiyohiro Oshima

“…The plasma levels of these agents and the conditions of resuscitation were compared between the two groups. …”
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Advanced 3D bioprinted liver models with human-induced hepatocytes for personalized toxicity screening by Yue Ma, Runbang He, Bo Deng, Miaomiao Luo, Wenjie Zhang, Lina Mao, Wenxiang Hu, Yilei Mao, Huayu Yang, Pengyu Huang

“…Notably, h3DPLs demonstrated increased sensitivity to hepatotoxic agents such as acetaminophen (APAP), making them a promising platform for studying drug-induced liver injury. …”
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Electroacupuncture Mitigates Hippocampal Cognitive Impairments by Reducing BACE1 Deposition and Activating PKA in APP/PS1 Double Transgenic Mice by Yinshan Tang, Shujun Shao, Yu Guo, You Zhou, Jin Cao, Anping Xu, Jihong Wu, Zhigang Li, Dulian Xiang

“…Therefore, revealing the underlying mechanism of BACE1 in the pathogenesis of AD might have a significant impact on the future development of therapeutic agents targeting dementia. This study examined the effects of electroacupuncture (EA) stimulation on BACE1, APP, and p-PKA protein levels in hippocampal tissue samples. …”
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Two Cysteines in Raf Kinase Inhibitor Protein Make Differential Contributions to Structural Dynamics In Vitro by Hyun Sang Cho, Mohammad Faysal Al Mazid, Eun-Young Lee, Md Abu Rayhan, Hyoun Sook Kim, Byung Il Lee, Hye Jin You

“…Taken together, our findings suggest that it may be possible to regulate RKIP function by controlling its dynamics with reducing agents, which could aid the targeting of cancer cells.…”
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PAB-Mamba-YOLO: VSSM assists in YOLO for aggressive behavior detection among weaned piglets by Xue Xia, Ning Zhang, Zhibin Guan, Xin Chai, Shixin Ma, Xiujuan Chai, Tan Sun

“…Within the proposed model, a novel CSPVSS module, which integrated the Cross Stage Partial (CSP) structure with the Visual State Space Model (VSSM), has been developed. This module was adeptly integrated into the Neck part of the network, where it harnessed convolutional capabilities for local feature extraction and leveraged the visual state space to reveal long-distance dependencies. …”
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Antibiotic Susceptibility of Bacteria Isolated from Open Fracture Grade III Presenting to Dr. Soetomo General Academic Hospital Surabaya by Raden Taufan Mulyo Wibisono, Dwikora Novembri Utomo, Agung Dwi Wahyu Widodo

“…An antibiotic susceptibility testing of patient specimen bacteria with open fractures aimed to determine suitable antibiotic agents with which to treat the infectious diseases caused by these bacteria. …”
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Responses of bimetallic Ag/ZnO alloy nanoparticles and urea on morphological and physiological attributes of wheat by Maria Ehsan, Naveed Iqbal Raja, Zia‐ur‐Rehman Mashwani, Muhammad Ikram, Efat Zohra, Syeda Sadaf Zehra, Fozia Abasi, Mubashir Hussain, Muhammad Iqbal, Nilofar Mustafa, Asad Ali

“…Nanotechnology modifies conventional agricultural practices as these are stimulating agents for plant growth. Green bimetallic Ag/ZnO alloy nanoparticles (NPs) synthesised from salts reduced by Moringa oleifera and characterised by UV‐visible spectroscopy, scanning electron microscopy, and energy‐dispersive X‐ray spectroscopy are studied herein. …”
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Activation of GPR119 Stimulates Human β-Cell Replication and Neogenesis in Humanized Mice with Functional Human Islets by Ansarullah, Colette Free, Jenica Christopherson, Quanhai Chen, Jie Gao, Chengyang Liu, Ali Naji, Alex Rabinovitch, Zhiguang Guo

“…Human islets were transplanted under the left kidney capsule of immunodeficient mice with streptozotocin- (STZ-) induced diabetes. …”
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The role of the interleukin family in liver fibrosis by Zixin Zhang, Zixin Zhang, Jiahui Wang, Hui Li, Qun Niu, Qun Niu, Yujing Tao, Yujing Tao, Xin Zhao, Xin Zhao, Zijian Zeng, Zijian Zeng, Haijian Dong, Haijian Dong

“…Liver fibrosis represents a wound-healing response to chronic liver injury caused by viral infections, alcohol, and chemicals agents. It is a critical step in the progression from chronic liver disease to cirrhosis and hepatocellular carcinoma. …”
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Tailored biomimetic nanoreactor improves glioma chemodynamic treatment via triple glutathione depletion and prompt acidity elevation by Ya Wen, Qiansai Qiu, Feng Feng, Yujuan Zhu, Jianquan Zhang, Zesheng Sun, Tuodi Zhang, Wei Shi, Jinlong Shi

“…Even worse, the various physiological barriers, especially in glioma, further put the brakes on the targeted delivery of Fenton agents. Herein, by exploring the thiol reaction potential of 5,5′-dithiobis-2-nitrobenzoic acid (DTNB), we have constructed a tailored biomimetic nanoreactor to improve glioma CDT efficacy through synchronous GSH exhaustion and acidity elevation. …”
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Biosynthesis and in-vitro characterizations of copper oxide nanoparticle using Mangifera indica seed kernel extract and assessment of pharmacological properties by Pranay Pramanik, Krishnendu Dakua, Trisha Kar, Ranabir Sahu, Tarun Kumar Dua, Gouranga Nandi, Sangita Dey, Anoop Kumar, Ritu Khanra, Paramita Paul

“…FTIR analysis inveterate the occurrence of phytochemicals in both the mango seed kernel extract as well as the nanoparticles, suggesting the kernel's potential as stabilizers, reducers, and capping agents. DPPH free radical scavenging assay indicated the CONPs to have mild antioxidant activity with IC50 of 453.72 μg/mL. …”
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Emergence of Highly Multidrug-Resistant Bacteria Isolated from Patients with Infections Admitted to Public Hospitals in Southwest Iran by Sepide Namdari, Ali Farhadi, Aida Khademalhoseini, Abbas Behzad-Behbahani, Afsaneh Moaddeb

“…This study highlights the emergence of MDR bacterial agents such as Acinetobacter species as a new threat in our region. …”
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Pharmacological regression of atherosclerotic plaque in patients with type 2 diabetes by Loredana Bucciarelli, Daniele Andreini, Giulio Stefanini, Roberta Maria Fiorina, Marco Francone, Federica Catapano, Maria Elena Lunati, Edoardo Conte, Davide Marchetti, Paolo Fiorina

“…Atherosclerosis of the coronary arteries continues to be one of the major global health burdens and acute coronary syndrome is responsible annually for at least 30 % of all deaths globally. …”
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Insectos y ácaros asociados a pimiento ¿Cuánta diversidad puede ser observada en un cultivo? by Ketty Lisbeth Meza Vera, José Velasquez, Dorys T. Chirinos

“…La identificación de los artrópodos plagas representa la primera fase para consecutivamente evaluar la magnitud de sus daños en combinación con la acción de los enemigos naturales para definir su importancia como agentes biológicos de regulación. …”
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Electrocoagulation of wastewater from commercial mixing stations with dual aluminum electrode by NI Kuan, SHAN Xiaoli, QI Dong, LI Qiang, ZHANG Wenjun

“…A dual aluminum electrode electrocoagulation method was proposed to achieve efficient flocculation settlement and clarification regeneration of strongly alkaline wastewater from commercial mixing station without agents. The turbidity variation of wastewater from commercial mixing stations with electrolysis time, operating voltage, and electrode configuration mode was investigated through orthogonal experiments, and the effects of three factors on floc chord length were examined using focused beam reflectance measurement(FBRM). …”
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Comparison the Efficacy of Fluconazole and Terbinafine in Patients with Moderate to Severe Seborrheic Dermatitis by Narges Alizadeh, Hamed Monadi Nori, Javad Golchi, Shahriar S. Eshkevari, Ehsan Kazemnejad, Abbas Darjani

“…Background. Topical agents can be unpleasant due to long-term therapies in patients with moderate to severe seborrheic dermatitis. …”
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Helicobacter pylori y cáncer gástrico by Ludmila Martínez Leyva, Teresita de Jesús Montero González, Felipe Neri Piñol Jiménez, Amada Belquis Palomino Besada, Miguel González-Carbajal Pascual, Danay Días Morejón

“…Desarrollo: El adenocarcinoma es el tumor gástrico más frecuente y el Helicobacter pylori es el agente etiológico principal. En poblaciones de riesgo elevado, el adenocarcinoma gástrico de tipo intestinal, se precede de lesiones preneoplásicas (atrofia, metaplasia intestinal y displasia) que evoluciona al cáncer invasor. …”
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Case report: Spontaneous renal hemorrhage in anti-neutrophil cytoplasmic antibody-associated vasculitis by Ruohan Yu, Lina Zhang, Ting Long, Hui Gao, Jing Xu, Tong Zhang, Shengguang Li

“…The average patient age was 54.5 years, and ranged from 25 to 82 years. Acute flank pain was the most common clinical manifestation, and was occasionally accompanied by anemia and shock. …”
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Optimizing feedback reception: a scoping review of skills and strategies for medical learners by Jennifer Rowe, Diane Bouchard Lamothe, Teagan Haggerty, Jake Engel, Cole Etherington, Manvinder Kaur, Etienne Vincent, Nibras Ghanmi, Preet Gujral, Valentina Ly, Sylvain Boet

“…Conclusion: The six included studies outline nine strategies and seven skills for improved learner feedback reception, focusing on overall approach and agentic behaviours without evaluation of the strategies or skills in practice. …”
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Design of the Multi-Bioactive Graphene-Oxide/Gelatin/Alginate Scaffolds as Dual ECM-Mimetic and Specific Wound Healing Phase-Target Therapeutic Concept for Advanced Wound Healing by Marko Demenj, Martina Žabčić, Marija Vukomanović, Tatjana Ilić-Tomić, Dušan Milivojević, Simonida Tomić, Dubravka Živanović, Marija M. Babić Radić

“…<b>Methods:</b> The scaffolds were engineered as interpenetrating polymeric networks by the crosslinking reaction of gelatin in the presence of alginate and characterized by structural, morphological, mechanical, swelling properties, porosity, adhesion to the skin tissue, wettability, and in vitro simultaneous release of the active agents. Biocompatibility of the scaffolds were evaluated in vitro by MTT test on fibroblasts (MRC5 cells) and in vivo using <i>Caenorhabditis elegans</i> assay. …”
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