Antimicrobial and Cytotoxicity Activities of Medicinal Plants against Salmonella gallinarum Isolated from Chickens by Mwanaisha Mkangara, Fulgence N. Mpenda

“…Aloe secundiflora leaf ethyl acetate (ALEA), Aloe rabaiensis leaf methanolic (ArM), Aloe rabaiensis leaf ethyl acetate (ArLEA), and Punica granatum leaf ethyl acetate (PGLEA) extracts exhibited the highest MIC (0.3906 mg/mL) and MBC (3.125 mg/mL), respectively. …”
Get full text

Recent advances in the management of knee osteoarthritis: a narrative review by Viktor Shtroblia, Pavlo Petakh, Iryna Kamyshna, Iryna Halabitska, Oleksandr Kamyshnyi

“…Nonpharmacological treatments, such as transcutaneous electrical nerve stimulation (TENS), acupuncture, and local heat therapy, provide variable pain relief and should be customized based on individual patient responses. Targeted biologic agents, such as antibodies to TNF-α, IL-1, and NGF, hold promise for more precise pain relief; however, further research is required to establish their routine use. …”
Get full text

The Importance of Natural Indigo Dye and Its Revitalization and Ethiopian Potential for Indigo Growing by Abera Kechi Kabish, Molla Tadesse Abate, Zelalem Adane Alemar, Solomon Girmay

“…Furthermore, currently, natural indigo dye is demanding for functional textile finishing, cosmetics and food colouration, UV protection and deodorizing agents, and other applications. In general, because of its increasing demand and wide applications, natural indigo has become an important cash crop and is traded in the international market with a price range of 35 to 40 USD per kilogram as per its purity level. …”
Get full text

Extracellular Cold-Inducible RNA-Binding Protein and Hemorrhagic Shock: Mechanisms and Therapeutics by Naureen Rashid, Zhijian Hu, Asha Jacob, Ping Wang

“…We also share our more newly developed anti-eCIRP agents with the eventual goal of producing drug therapies to mitigate organ damage, reduce mortality, and improve patient outcomes related to hemorrhagic shock. …”
Get full text

Comparative Microstructural Evaluation of Wood in Three Dominant Ziziphus Species of Desert Ecosystem (Cholistan), Pakistan by Muhammad Bilal, Zaheer-ud-din Khan, Sohaib Muhammad, Uzma Hanif, Khalid Hussain, Muhammad Tayyab, Andleeb Anwar Sardar, Hassan Nawaz, Muhammad Jawad Tariq Khan, null Mahrukh, Aneela Rasool, Summiya Faisal, Muhammad Zahid

“…The number of rays per mm was comparatively larger in Ziziphus nummularia, showing its greater susceptibility to wood-deteriorating agents than in other selected species. The Runkel ratio indicated the selected species suitable for making paper.…”
Get full text

Mia Couto and the enchantment of rain by Myrtle J. Hooper, Isabel B. Rawlins

“…This article explores the range of roles, agentic and enchanted, which Couto accords rain in his stories. …”
Get full text

SARS-CoV-2: Molecular Structure, Pathogenesis, Potential Therapeutic Targets, and Immune Response of the Infected Subject by R. Wumba, M. Mandina, Y. Nlandu, J. R. Makulo, A. Tshimpi, P. Mbala, A. Mbangama, P. Kabututu, J. M. Kayembe

“…Reported data could contribute to a better understanding of molecular mechanisms of cellular infection by SARS-CoV-2 as well as to a more easy explanation of the action of pharmacological agents used for the treatment, while elucidating intimate mechanisms of the immunity of infected subject.…”
Get full text

Current Perspectives in Detection of Bioactive Compounds From Costus spicatus Through GC–MS and LC-MS/MS: Antioxidant Properties and In Silico Analysis for Industrial Applications... by Dharmar Manimaran, Ararsa Tessema, M. Govindarajulu Yadav, S. Parthasarathi, Vasan Palanisamy

“…They are cholestan-3-amine, loliolide, stigmasterol and methylprednisolone acetate, succinimide, fumaric acid, beta-tocopherol and gamma-tocopherol. …”
Get full text

Evaluation of Iron Deficiency Anemia Frequency as a Risk Factor in Glaucoma by Penpe Gul Firat, Ersan Ersin Demirel, Seyhan Dikci, Irfan Kuku, Oguzhan Genc

“…No statistically significant difference was found in the comparison of erythrocyte parameters and iron status indicators values according to the number of antiglaucomatous agents and visual field changes according to the presence of anemia in Group 2 (p≥0.05). …”
Get full text

An Update on Gastrointestinal Parasitic Infection in Captive Wild Animals in Bangladesh by Rehana Rahman, Jannatul Nyema, Md. Imranuzzaman, Bijoy Banik, Proshanto Singha Pranto, Kanan Talukder, Susmita Rani Sarkar, Shampa Deb Nath, Kazi Mehetazul Islam, Tilak Chandra Nath, Saiful Islam

“…The aim of the study is to describe parasitic causal agents in captive wild animals at the Bangladesh National Zoo, Chittagong Zoo, and Tilagarh Eco Park, in Sylhet. …”
Get full text

Atención a la diversidad en la educación parvularia: un enfoque neuropedagógico para el desarrollo infantil by Lenin Roberto Villalobos Egaña

“…Finalmente, la incorporación de la neuropedagogía en la formación docente fomenta estrategias inclusivas y personalizadas, transformándolo en mediador y agente de cambio. Es imprescindible fortalecer un currículo neuropedagógico que no solo explore teorías, sino que también profundice en prácticas pedagógicas y políticas educativas que potencien un entorno educativo más inclusivo y equitativo. …”
Get full text

Groundwater-Mixing Mechanism in a Multiaquifer System Based on Isotopic Tracing Theory: A Case Study in a Coal Mine District, China by Pinghua Huang, Xinyi Wang

“…To study the mixing mechanism of a multiaquifer groundwater system, groundwater samples were collected from different strata in a typical North China-type coalfield (Chaochuan Coal Mine) and were then tested using environmental isotopes (18O, 2H, 3H, 13C, and 14C) and hydrochemical ions (Ca2+, Mg2+, Na+, K+, HCO3−, SO42−, and Cl−) as tracer agents. Results demonstrate that HCO3− and Cl− exhibit a linear relationship with the mixing ratio, whereas Na+, Ca2+, and SO42− show certain degrees of curvature. …”
Get full text

ANÁLISE DE CORTISOL SALIVAR COMO RECURSO NA AVALIAÇÃO DO ESTRESSE OCUPACIONAL: UMA REVISÃO SISTEMÁTICA DA LITERATURA by Pedro Henrique Marques Andreo, Paulo Cesar Meletti

“…Mais da metade dos estudos não apresentaram uma comparação entre turnos de trabalho e dias de descanso. Além disso, a principal categoria investigada consistiu nos profissionais de saúde. …”
Get full text

Natural Cyclic Peptides: Synthetic Strategies and Biomedical Applications by Devan Buchanan, Shogo Mori, Ahmed Chadli, Siva S. Panda

“…These compounds are employed in diverse roles, including antibiotics, antifungals, antiparasitics, immune modulators, and anti-inflammatory agents. Their unique ability to combine high specificity with desirable pharmacokinetic properties makes them valuable tools in addressing unmet medical needs, such as combating drug-resistant pathogens and targeting challenging biological pathways. …”
Get full text

Why Does Pnemococcus Kill? by Yves Bergeron, Michel G Bergeron

“…Acute lower respiratory tract infections remain the most common cause of death due to infection worldwide, and Streptococcus pneumoniae is responsible for approximately 30% of all cases of community-acquired pneumonia. …”
Get full text

Synthesis and Characterization of Bioactive Acylpyrazolone Sulfanilamides and Their Transition Metal Complexes: Single Crystal Structure of 4-Benzoyl-3-methyl-1-phenyl-2-pyrazolin-... by Omoruyi G. Idemudia, Alexander P. Sadimenko, Anthony J. Afolayan, Eric C. Hosten

“…A moderate to low biological activities have been exhibited by synthesized compounds when compared with standard antimicrobial agents on screening the synthesized compounds against Staphylococcus aureus, Bacillus pumilus, Proteus vulgaris, and Aeromonas hydrophila for antibacterial activity and against free radical 1, 1-diphenyl-2-picryl-hydrazyl (DPPH) for antioxidant activity.…”
Get full text

Fabrication of glipizide loaded polymeric microparticles; in-vitro and in-vivo evaluation. by Qaiser Rasheed, Kamran Ahmad Khan, Ghulam Razaque, Ashfaq Ahmad, Asif Nawaz, Naheed Akhtar, Kifayat Ullah Shah, Zahid Rasul Niazi, Muhammad Danish Saeed, Anila Alam

“…In this study, we aimed to design controlled-release microparticles of Glipizide utilizing Eudragit S100 and Methocel K 100 M polymers as controlling agents. The microparticles were fabricated through a simple solvent evaporation method, employing various drug-to-polymer ratios to formulate different controlled-release batches labeled as F1 to F5. …”
Get full text

Identifying RBBP7 as a Promising Diagnostic Biomarker for BK Virus-Associated Nephropathy by Yicun Wang, Yuxuan Wang, Di Zhang, Hao Zhang, Wei Wang, Xiaopeng Hu

“…Besides, potential drugs for BKVN treatment such as mepacrine were discovered, which may contribute to targeted antiviral therapy and effective patient management rather than simply reducing the doses of immunosuppressive agents in clinical practice. RBBP7 (retinoblastoma binding protein 7) serves as component of serval complexes that regulate chromatin metabolism and functions in affecting DNA replication and controlling cell proliferation. …”
Get full text

Chitosan and its derivatives as promising plant protection tools by A. B. Shcherban

“…Recently, biological PPPs based on natural compounds have attracted more attention, since they do not have these disadvantages, but at the same time they can be no less effective. One of such agents is chitosan, a deacetylation product of chitin, one of the most common polysaccharides in nature. …”
Get full text

Relación entre depresión y adherencia al tratamiento en diabetes tipo 2, considerando la red de apoyo social, las estrategias de afrontamiento y el sexo by José Eduardo Rondón Bernard, Luisa Angelucci

“…Al evaluar los modelos de ecuaciones estructurales, se obtuvieron las mismas medidas de bondad de ajuste, con relaciones similares entre variables, por lo que ambos modelos poseen un ajuste aceptable. Ser mujer, poseer menor estrategia de evitación, presentar mayor red de apoyo, tener menor adherencia al tratamiento, conlleva a una menor depresión. …”
Get full text