Activating PKC-ε induces HIV expression with improved tolerability. by Alivelu M Irrinki, Jasmine Kaur, Bally Randhawa, Ryan McFadden, Chelsea Snyder, Hoa Truong, Daniel Soohoo, Eric Hu, Helen Yu, Bernard P Murray, Bing Lu, Dmytro Kornyeyev, Ishak Darryl Irwan, Lan Nguyen, Yu-San Yang, Jean-Philippe Belzile, Uli Schmitz, Todd C Appleby, Brian Schultz, Jay Lalezari, Steven Deeks, Tomas Cihlar, Jeffrey P Murry

“…Protein kinase C (PKC) isozymes increase HIV transcription and hence are potential latency reversal agents. However, the clinical utility of PKCs for this application is limited due to toxicity, which is poorly understood. …”
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Isolation and Identification of Marine Bacteria in Raja Ampat Islands West Papua Producing Antibacterial Against Salmonella typhi and Staphylococcus aureus by Dede Mahdiyah, Muhammad Rifqi Dharmawan, Noval Noval

“…Given the increasing prevalence of antibiotic resistance, particularly against Salmonella typhi and Staphylococcus aureus, there is a pressing need to explore alternative antimicrobial agents. This study aimed to isolate and characterize marine bacteria with antibacterial activity and evaluate their efficacy against S. typhi and S. aureus. …”
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Multi-target regulatory effects of rhaponticin in a rat model of hepatic fibrosis revealed by non-targeted metabolomics by Min Yang, Dihua Jiang, Longfei Huang, Tao Zhang, Wenfen Guo, Wenyan Lin, Jiali Zhao, Yunsheng Wei, Lang Peng, Yong-Jia Hao, Ying Zhou

“…The lack of preventive and therapeutic strategies has created an urgent need for effective anti-fibrosis agents. There is growing evidence that natural products might provide safe and effective interventions for HF. …”
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A compatibilidade da prática de zero-rating com a previsão de neutralidade de rede by Caio Mario da Silva Pereira Neto, Ronaldo Lemos, Mateus Piva Adami, Felipe Moreira de Carvalho

“…A partir da interpretação desenvolvida em conformidade com o preceito constitucional da livre-iniciativa e também com a legislação setorial de telecomunicações - à qual os provedores de conexão à internet, enquanto agentes privados, estão sujeitos -, procura-se explicar a legalidade da prática de ofertas zero-rating, que fazem parte do âmbito de liberdade negocial dos entes privados. …”
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INTERPASSIVITY AS A SUBJECTIVE EFFECT OF MODERN MEDIA-CULTURE: TO THE STATEMENT OF PROBLEM by Olena V. Khodus

“…It is proved that in the modern media culture, the subject is not so much a passive spectator, observer, collector information and events to represent relevant interested agents. He also actively reproduces itself in a form of "perceived privacy", which allows special mode of the experiences of private emotions "alone with everybody." …”
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Release of P-TEFb from the Super Elongation Complex promotes HIV-1 latency reversal. by William J Cisneros, Shimaa H A Soliman, Miriam Walter, Lacy M Simons, Daphne Cornish, Simone De Fabritiis, Ariel W Halle, Eun-Young Kim, Steven M Wolinsky, Ramon Lorenzo-Redondo, Ali Shilatifard, Judd F Hultquist

“…KL-2 acts synergistically with other latency reversing agents (LRAs) to reactivate viral transcription in several cell line models of latency in a manner that is, at least in part, dependent on the viral Tat protein. …”
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Respiratory diseases in young cattle by T. S. Ermilova, M. A. Samburova, O. V. Kasharnaya, E. A. O. Salimzade

“…However, out of the major calf diseases, particular mention should be made of pneumonia, which is most often caused by viruses. In this case agents can induce bacterial infection which aggravates and complicates the course of viral diseases. …”
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Consensus guidelines for the management of treatment-naïve chronic lymphocytic leukaemia in Singapore (2024) by Yeow Tee Goh, Yvonne Loh, Esther Chan, Yuh Shan Lee, Venkata Sreekanth Sampath, Daryl Tan, Shin Yeu Ong, Chandramouli Nagarajan

“…Due to the superior efficacy of targeted agents (Bruton's tyrosine kinase inhibitors [BTKis] and B-cell lymphoma 2 inhibitors [BCL2is]), sthese are favoured over standard chemotherapy or chemotherapy-immunotherapy, especially for patients with del(17p) or TP53 mutation, and less fit patients. …”
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The Effect of Prucalopride on Small Bowel Transit Time in Hospitalized Patients Undergoing Capsule Endoscopy by Majid Alsahafi, Paula Cramer, Nazira Chatur, Fergal Donnellan

“…VCE studies were excluded if the capsule was retained or endoscopically placed, if other prokinetic agents were given, in cases with technical failure, or if patients had prior gastric or small bowel resection. …”
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ENTROPY INDICATORS FOR AN ESTIMATION OF CURRENCY RISKS by Valeria Yatsenko

“…Since statistical methods of currency risk assessment do not always guarantee a reliable reflection of potential threats due to the noise in financial time series or irrational agents’ behaviour, it is necessary to search for alternative risk measurement methods. …”
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Anticancer potential of coumarins from the Ferulago genus by Mansour Mofasseri, Elham Eini, Saber Mofasseri, Bahram Hanifehpour, Fatemeh Zanbili, Ahmad Poursattar Marjani

“…Cancer treatment needs better therapeutic agents with fewer side effects compared to the present anticancer and antitumor drugs. …”
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A Novel Modeling Technique for the Forecasting of Multiple-Asset Trading Volumes: Innovative Initial-Value-Problem Differential Equation Algorithms for Reinforcement Machine Learni... by Mazin A. M. Al Janabi

“…In this paper, we do not propose a definitive one either, but we attempt to derive novel mathematical algorithms for the dynamic modeling of trading volumes during the closeout period from the perspective of multiple-asset portfolio(s), as well as for financial entities with different subsidiary firms and multiple agents. The robust modeling techniques are based on the application of initial-value-problem differential equations technique for portfolio selection and risk management purposes. …”
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INFLUÊNCIA DO EXERCÍCIO SOBRE A PRODUÇÃO DE RADICAIS LIVRES by Rodrigo Luiz Vancini, Claudio Andre Barbosa de Lira, Dilmar Pinto Guedes Júnior, Antonio Carlos da Silva, Viviane Louise Andrée Nouailhetas

“…O exercício crônico moderado e asuplementação de antioxidantes podem reduzir os danos celulares induzidos por diferentes agentes estressoresaos quais o organismo é submetido, pois promovem proteção por meio de diferentes mecanismos, e quandopresentes de forma combinada, providenciam proteção adicional contra a ação deletéria dos RL.…”
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Pobreza subnacional en México y el Fondo de Aportaciones para Infraestructura Social by Cesar Gurrola Ríos, Paola Vázquez Molina

“…Los resultados del estudio son relevantes para agentes económicos interesados en mejorar las condiciones de vida de la población mexicana a través del diseño, implementación y monitoreo de políticas públicas orientadas a combatir la pobreza en México.…”
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Diseño de una red de participación de actores para la gestión de los sistemas de financiamiento by Laura Angelina Obando Uzcátegui, Juan Carlos Delgado Barrios

“…Una de las maneras de impulsar el desarrollo económico local en las regiones es mediante la integración de esfuerzos de los agentes locales en redes de participación, con la intención de gestionar mancomunadamente intereses en común. …”
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Comparative metabolic study of planktonic and sessile cells in Salmonella Enteritidis ATCC 13076: Elucidating metabolic pathways driving biofilm formation. by Yuliany Guillín, Claudia Ortiz, William Hidalgo

“…Microorganisms tend to accumulate on surfaces, forming aggregates such as biofilms, which grant them resistance to various environmental stressors and antimicrobial agents. This ability has hindered the effective treatment of diseases caused by pathogenic microorganisms, including Salmonella, which is responsible for a significant number of deaths worldwide. …”
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Primera evidencia de Chlamydia psittaci en huron sable (Mustella putorios furo) en Venezuela by C. Rodríguez-Leo, D. Camacho, V. Hernández-Aguilera, M. Viettri, C. Flores, H. Henríquez, M. González

“…Se desconoce el total de reservorios de Cp, por ello la notificación de los aislados permite el entendimiento, distribución y diversidad de agentes clamidiales en fauna silvestre y en cautiverio.…”
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TEORIA DISCURSULUI: APLICABILITATE ÎN ANALIZA SCHIMBĂRILOR DE PARADIGMĂ ÎN STUDIILE DE SECURITATE by Robert-Ionuț STANCIU

“…Using language in specific ways can influence institutional behavior in a manner favorable to the sender, provided that the promoters of the messages are referential authorities called hegemonic agents. Based on these benchmarks, we believe and prove that the use of methodological language/speech analysis mechanisms could provide a priori relevant information regarding intentions, objectives and positions that the issuer can adopt. …”
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The Policies of Balai Pustaka as the Dutch Colonial Government’s Publishing Agency in 1917-1942 by Sulistya Putri, Dewi Yuliati, Dhanang Respati Puguh

“…Meanwhile, postproduction policy was in the form of distribution of script by establishing more Taman Pustaka, expanding sales agents, and performing mobile library program. Other than these, Balai Pustaka also actively sued publication which were not published by it and by idea and notion opposing the colonial government.…”
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Roles, challenges, and resiliency during the COVID-19 pandemic: a case of women political leaders in the Philippines by Mark Erana Patalinghug, Ann Mariel P. Majorenos, Rezin I. Tigley

“…The study highlights that these female leaders adeptly managed the pandemic's challenges through effective cooperation and collaboration with stakeholders, underpinned by a commitment to altruism. …”
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