Application of therapeutical nanoparticles with neutrophil membrane camouflaging for inflammatory plaques targeting against atherosclerosis by Ningnannan Zhang, Tianzhu Zhang, Jintang Feng, Jian Shang, Beibei Zhang, Qingyang Dong, Zhang Zhang, Chunyang Sun

“…This approach of neutrophil membrane-camouflaged nanoparticles offers new opportunities to various therapeutic agents for on-demand delivery in neutrophil-involved inflammatory diseases.…”
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Design, synthesis, and apoptotic antiproliferative action of new benzimidazole/1,2,3-triazole hybrids as EGFR inhibitors by Alshimaa A. Y. Ahmed, Anber F. Mohammed, Zainab M. Almarhoon, Stefan Bräse, Bahaa G. M. Youssif

“…IntroductionThis work outlines the design, synthesis, and biological evaluation of a new series of benzimidazole/1,2,3-triazole hybrids as apoptotic antiproliferative agents that inhibit the EGFR pathway.MethodsThe research assesses the antiproliferative efficacy of compounds 6a-i and 10a-i against various cancer cell lines.Results and DiscussionThe research emphasizing hybrids 6i and 10e for their remarkable activity, with GI50 values of 29 nM and 25 nM, respectively. …”
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The anti-melanoma roles and mechanisms of tricholoma isoflavone derivative CA028 by Cheng Liang, Jianfu Jiang, Jinkai Li, Xiao Lin, Wenjun Huang, Keng Po Lai, Jian Chen

“…Therefore, there is an urgent need to find new agents to improve survival in melanoma patients. Isoflavones, a class of phytoestrogens, are primarily found in soy and other legumes. …”
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From polymer matrix to cell structure: STG/TEMs/PU energy-absorbing foamed composites with strain rate-dependent and bimodal cellular structure by Xiaoke Liu, Kejing Yu, Pengwan Chen

“…In this study, based on polyurethane (PU) foam material, intelligent macromolecular material “shear thickening gel (STG)” with strain rate-dependent characteristic was chosen as the reinforcing material to strengthen the PU matrix, and water together with thermal expansion microspheres (TEMs) were used as double foaming agents to prepare STG/TEMs/PU foamed composites with bimodal cell structure and excellent mechanical properties. …”
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Induction of tyrosine aminotransferase in mice is inhibited by activated metabolites of ortho- aminoazotoluene by V. I. Kaledin, S. I. Ilnitskaya, N. A. Popova, O. A. Koval, I. A. Pyshnaya, L. F. Gulyaeva

“…In contrast, nonspecific genotoxic agents such as cyclophosphamide and cisplatin exert no effect on TAT induction by glucocorticoids. …”
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Case report: Dysphonia associated with high-dose cytarabine therapy by Ling Ma, Niya Huang, Haixi Zhang, Jia Liu, Zhiqing Zhang

Subjects: “…acute myeloid leukemia…”
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Mesenchymal Stem Cell-Based Therapy of Inflammatory Lung Diseases: Current Understanding and Future Perspectives by C. Randall Harrell, Ruxana Sadikot, Jose Pascual, Crissy Fellabaum, Marina Gazdic Jankovic, Nemanja Jovicic, Valentin Djonov, Nebojsa Arsenijevic, Vladislav Volarevic

“…During acute or chronic lung injury, inappropriate immune response and/or aberrant repair process causes irreversible damage in lung tissue and most usually results in the development of fibrosis followed by decline in lung function. …”
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A Novel Complex Event Processing Engine for Intelligent Data Analysis in Integrated Information Systems by Dong Wang, Mingquan Zhou, Sajid Ali, Pengbo Zhou, Yusong Liu, Xuesong Wang

“…These operators and rules have been utilized for constructing new CEP system architecture which combines expressiveness and efficiency in analysis. It adopts the agents and filter conception explicitly to provide the event transmission mechanism efficiently. …”
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Recent development of micro-nano carriers for oral antineoplastic drug delivery by Hongzheng Li, Xiang Chen, Shangrui Rao, Minyu Zhou, Jianhua Lu, Danna Liang, Bingzi Zhu, Letian Meng, Ji Lin, Xiaoya Ding, Qingfei Zhang, Danhong Hu

“…Chemotherapy is widely recognized as a highly efficacious modality for cancer treatment, involving the administration of chemotherapeutic agents to target and eradicate tumor cells. Currently, oral administration stands as the prevailing and widely utilized method of delivering chemotherapy drugs. …”
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A comprehensive review on nutritional composition, health benefits, and industrial applications of Jackfruit Seeds by Simran Dhani, Hamid, Nomali Ziphorah Ngobese, Sunny Sharma, Amit K. Jaiswal

“…Furthermore, starch extracted from discarded jackfruit seeds can be utilized as thickeners, gelling agents and fillers meanwhile its potential applications in the pharmaceutical industry. …”
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An analytical disquisition on the nonlinear optical responses of carbon quantum dots engineered by diverse synthesis methodologies by Rashi Mahendra Patil, Akshay Raj R, Shyamal Mondal, Tejashree Bhave, Appala Venkata Ramana Murthy

“…Meanwhile, the green synthesis method, utilizing natural resources and organic precursors which replaced by chemical capping agents such as PEG, showed a moderate NLO response (χ(3) = 2.72 × 10–7 esu), influenced by diverse surface functionalities. …”
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Glycosylation Patterns in <i>Meccus (Triatoma) pallidipennis</i> Gut: Implications for the Development of Vector Control Strategies by Elia Torres-Gutiérrez, Frida Noelly Candelas-Otero, Olivia Alicia Reynoso-Ducoing, Berenice González-Rete, Mauro Omar Vences-Blanco, Margarita Cabrera-Bravo, Martha Irene Bucio-Torres, Paz María Silvia Salazar-Schettino

“…Furthermore, the potential use of lectins as insecticidal agents highlights the broader implications of glycoprotein research in the future development of strategies on vector control to disrupt <i>T. cruzi</i> transmission.…”
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GNQ-209P Mutation in Metastatic Uveal Melanoma and Treatment Outcome by Nagla Abdel Karim, Ihab Eldessouki, Ahmad Taftaf, Deeb Ayham, Ola Gaber, Abouelmagd Makramalla, Zelia M. Correa

“…However, until the discovery of novel agents, local versus systemic therapies remain options for treatment that can still be considered for disease control in certain cases. …”
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Mold Alkaloid Cytochalasin D Modifies the Morphology and Secretion of fMLP-, LPS-, or PMA-Stimulated Neutrophils upon Adhesion to Fibronectin by Svetlana I. Galkina, Natalia V. Fedorova, Marina V. Serebryakova, Evgenii A. Arifulin, Vladimir I. Stadnichuk, Ludmila A. Baratova, Galina F. Sud’ina

“…Cytochalasin D impaired the MMP-9 secretion but initiated the release of cathepsin G and other granular bactericides, proinflammatory agents. The release of bactericides apparently occurs through the formation, shedding, and lysis of cytonemes. …”
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High-density lipoprotein nanoparticles spontaneously target to damaged renal tubules and alleviate renal fibrosis by remodeling the fibrotic niches by Shanshan He, Xiaoyang Li, Yuanyuan He, Ling Guo, Yunzhou Dong, Leilei Wang, Lan Yang, Lin Li, Shiyun Huang, Jiali Fu, Qing Lin, Zhirong Zhang, Ling Zhang

“…Thus, this system is promising for the treatment of CKD and bHDL has good potential for delivering agents to damaged renal tubular epithelial cells.…”
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Green hydrothermal synthesis of nickel and zinc-doped nickel ferrite nanoparticles using Dalbergiella welwitschii extracts and their biological studies by Oghenejoboh Ufuoma Modupe, Sonibare Oluwadayo Olatunde, Muhammad Waseem, Ekundayo Olusegun, Sirajul Haq, Ahad Amer Alsaiari, Jamoliddin Razzokov

“…Dalbergiella welwitschii mediated nanoparticles of Ni/Fe and Ni/Fe/Zn could be further explored as alternative therapeutic agents for cancer and diabetes.…”
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Synthetic peptides as valuable and versatile tools for research: our 20 year journey in Chile by Constanza Cárdenas, Paula Santana, Claudio Álvarez, Luis Mercado, Sergio Marshall, Fernando Albericio, Fanny Guzmán

“…They are ubiquitous across the evolutionary scale, fulfilling a wide variety of functions, from immune system effectors in simple organisms to signaling or neuromodulating agents in high vertebrates. Following nature’s example, peptides have emerged as alternatives in various fields. …”
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Processo de trabalho do profissional de Educação Física na atenção básica em territórios rurais by Fernando de Lima, Maria Deisyelle Sibaldina da Silva Almeida, Taynara Poliana Gonçalves de Melo, Wellington da Silva Rodrigues Junior, Nicole Caroline Nascimento da Silva, Ranieri Moreira da Silva, Larissa Manuelle Marciano Francisco, Danyela Lays dos Santos, Itamar Lages, Emmanuelly Correia de Lemos

“…O processo de trabalho dos profissionais de Educação Física no campo é marcado por agentes, objetos, meios, produtos e resultados que caracterizam o trabalho na Atenção Primária, composto por ações de núcleo e outras abrangentes, além das especificidades da área. …”
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Enhancing antimicrobial resistance strategies: Leveraging artificial intelligence for improved outcomes by Aeshah M. Mohammed, Mohammed Mohammed, Jawad K. Oleiwi, Azlin F. Osman, Tijjani Adam, Bashir O. Betar, Subash C.B. Gopinath, Falah H. Ihmedee

“…This review not only highlights AI's potential to enhance AMR management but also calls for a concerted effort to harness its capabilities, thereby safeguarding the efficacy of antimicrobial agents and ensuring a sustainable healthcare future.…”
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Antimicrobial membranes based on polycaprolactone:pectin blends reinforced with zeolite faujasite for cloxacillin-controlled release by Bárbara Bernardi, João Otávio Donizette Malafatti, Ailton José Moreira, Andressa Cristina de Almeida Nascimento, Juliana Bruzaca Lima, Lilian Aparecida Fiorini Vermeersch, Elaine Cristina Paris

“…Abstract Multifunctional membranes applied to biomedical materials become attractive to support the biological agents and increase their properties. In this study, biopolymeric fibers based on polycaprolactone (PCL) and pectin (PEC) were reinforced with faujasite zeolite (FAU) for cloxacillin antibiotic (CLX) loading. …”
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