Acne Vulgaris Management: A Review of First-Line and Advanced Pharmacological Treatments by Krzysztof Dobrzeniecki, Anna Zygmunt, Karolina Karoń, Łukasz Karoń, Patrycja Karnas-Bogacka

“…Review methods: The literature review utilized databases covering sources from PubMed, Google Scholar, Scopus, and Web of Science using the search terms encompassing the following keywords: ‘acne vulgaris’ and ‘topical retinoid therapy’, ‘benzoyl peroxide’, ‘azelaic acid’, ‘topical antibiotics’, ‘oral antibiotics’, ‘contraceptive agents’, ‘antiandrogen therapy’, ‘isotretinoin’. …”
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Advances in the biosynthesis of naturally occurring benzylisoquinoline alkaloids by Wanli Zhao, Jihua Liu, Yu Chen

“…Examples include analgesics such as morphine, tetrahydropalmatine, antimicrobials such as berberine, and antineoplastic agents including cepharanthine. Most BIAs are derived and isolated from medicinal plants; however, these plants are predominantly wild resources that are scarce. …”
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Multifunctional drug delivery nanoparticles for combined chemotherapy/chemodynamic/photothermal therapy against colorectal cancer through synergistic cuproptosis/ferroptosis/apopto... by Xiuzhang Yan, Heshi Liu, Lei Guo, Chang Liu, Shichen Zhang, Xue Wang, Yixin Tang, Rui Zhou, Xin Jiang, Erlei Wang, Shuohui Gao, Caina Xu

“…On the one hand, the DFMTCH NPs exhibited a range of therapeutic capabilities, including chemotherapy, photothermal therapy (PTT), and chemodynamic therapy (CDT), which collectively enhanced the anti-tumor efficacy of chemotherapeutic agents. In addition, DFMTCH NPs proved sensitive photoacoustic imaging (PAI) in image-guided therapy. …”
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From St Winifred’s Translation to Medieval Whodunnit: Ellis Peters and the Cadfael Chronicles by Catherine Lanone

“…Le personnage du moine-détective offre une variation intéressante sur celui du détective retiré du monde, amplifiant la retraite en monastère, tout en ajoutant un passé tumultueux aux Croisades qui fait de Cadfael un homme qui connaît les méandres des désirs humains. …”
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A state-of-the-art review of research on the use of calcined bauxite aggregate in civil engineering by Yalin Liu, Chengze Li, Ya Wei, Linbing Wang

“…This study describes in detail the macroscopic and microscopic properties of CB aggregates, analyzes and summarizes the current research status of CB aggregates in many aspects: 1) review the technique related to the manufacture of ultra-high performance concrete (UHPC) with CB aggregate, and systematically explain its mechanism in affecting the mechanical properties of UHPC; 2) clarify the potential and advantage of CB aggregates as internal curing agents, and elaborate the shrinkage reduction mechanism and the influence law when used in UHPC; 3) summarize the evaluation index system of CB aggregate in abrasion and skid resistance of pavement materials, as well as introduce related research and engineering applications of high friction surface treatment; 4) discuss the advantages of CB aggregate in preparation of high-impact resistant cementitious materials and its influence mechanism. …”
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Optimizing Acidic Reductive Leaching for Lithium Recovery: Enhancing Sustainable Lithium Supply for Energy Markets by Agnieszka Sobianowska-Turek, Amelia Zielińska, Weronika Urbańska, Anna Mielniczek, Agnieszka Fornalczyk, Szymon Pawlak, Tomasz Małysa, Janusz Cebulski

“…., acid concentration, reducing agents, temperature, and time) that could maximize lithium recovery while minimizing environmental and economic costs. …”
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Cardiovascular diseases in patients with cancer: A comprehensive review of epidemiological trends, cardiac complications, and prognostic implications by Ali A. Alshahrani, Evangelos Kontopantelis, Catharine Morgan, Rathi Ravindrarajah, Glen P. Martin, Mamas A. Mamas, Rongman Jia

“…Many chemotherapeutic agents used to treat cancer are associated with cardiovascular complications (such as heart failure, myocardial infarction, and thrombosis). …”
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Efficacy of traditional herb aqua extract of Teucrium stocksianum and its fractions against HSV-1 virus expression levels of genes (UL46 and US6) by Emad Asgari, Zohreh Sharifi, Farahnaz Bineshian, Mahsa Zamanian

“…Conclusion: T. stocksianum, has an anti-viral property and may be considered as a remedy for anti-HSV-1 agents. …”
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B7-H4 Pathway in Islet Transplantation and β-Cell Replacement Therapies by Xiaojie Wang, Jianqiang Hao, Daniel L. Metzger, Ziliang Ao, Mark Meloche, C. Bruce Verchere, Lieping Chen, Dawei Ou, Alice Mui, Garth L. Warnock

“…More importantly, B7-H4 plays an indispensable role in alloimmunity in the absence of the classic CD28/CTLA-4 : B7 pathway, suggesting a synergistic/additive effect with other agents such as CTLA-4 on inhibition of unwanted immune responses.…”
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Improving the Implementation of Patient-Reported Outcome Measure in Clinical Practice: Tackling Current Challenges With Innovative Digital Communication Technologies by Kelly M de Ligt, Saar Hommes, Ruben D Vromans, Eva Boomstra, Lonneke V van de Poll, Emiel J Krahmer

“…We explore how existing principles and tools, such as automatic data-to-text generation (including multimodal outputs like text combined with data visualizations) and conversational agents, can enable personalized communication of PROMs in practice.…”
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Marine natural products as a source of novel anticancer drugs: an updated review (2019–2023) by Hesham R. El-Seedi, Mohamed S. Refaey, Nizar Elias, Mohamed F. El-Mallah, Faisal M. K. Albaqami, Ismail Dergaa, Ming Du, Mohamed F. Salem, Haroon Elrasheid Tahir, Maria Dagliaa, Nermeen Yosri, Hongcheng Zhang, Awg H. El-Seedi, Zhiming Guo, Shaden A. M. Khalifa

“…Finally, the review underscores the immense potential of marine natural products as a valuable reservoir of novel anticancer agents and advocates for continued exploration and exploitation of the marine environment to address the unmet medical needs in cancer therapy Graphical Abstract…”
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Estrogen-dependent activation of TRX2 reverses oxidative stress and metabolic dysfunction associated with steatotic disease by Alfredo Smiriglia, Nicla Lorito, Marina Bacci, Angela Subbiani, Francesca Bonechi, Giuseppina Comito, Marta Anna Kowalik, Andrea Perra, Andrea Morandi

“…In this study, we utilized preclinical in vitro models—immortalized cell lines and hepatocyte-like cells derived from human embryonic stem cells—exposed to clinically relevant steatotic-inducing agents. These exposures led to lipid droplet (LD) accumulation, increased reactive oxygen species (ROS) levels, and mitochondrial dysfunction, along with decreased expression of markers associated with hepatocyte functionality and differentiation. …”
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cGAS-STING targeting offers therapy choice in lung diseases by Yu Wang, Xuan Zhang, Weixue Wang, Yi Zhang, Joshua S. Fleishman, Hongquan Wang

“…Insights into the biology of the cGAS-STING pathway have enabled the discovery of small-molecule agents which have the potential to inhibit the cGAS-STING axis in lung diseases. …”
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Free Triiodothyronine and Cholesterol Levels in Euthyroid Elderly T2DM Patients by F. Strollo, I. Carucci, M. Morè, G. Marico, G. Strollo, M. A. Masini, S. Gentile

“…When divided according to treatment by oral hypoglycaemic agents (OHA) and insulin (IT), they reacted differently with respect to investigated associations: in the OHA’s TC and LDL-C correlated negatively with FT4 and showed no association with FT3, whereas, in the IT’s TC and LDL-C correlated positively with FT3 and negatively with FT4. …”
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Comparative Studies of Synthesized Copper Oxide Nanoparticles using Aqueous Extract of Leaves by Emmanuel Oyetola, Friday Nwosu, Gboyega Oluwaseun Oyeleke, Ismaila Olawale, Bosede Mofoluwake Adegoke, Usman Afolabi

“…The use of plant extracts as reducing agents in the synthesis of metal and metal oxide nanoparticles has come into prominence due to their procedural simplicity, precursor’s eco-friendliness, and cost effectiveness.  …”
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Primary Small Cell Carcinoma of the Hypopharynx: A Report of Two Cases and Review of Nine Additional Cases by Mitsuhiko Nakahira, Kiyomi Kuba, Satoko Matsumura, Masashi Sugasawa

“…Because this tumor has a strong propensity for distant metastasis even in patients with clinically localized tumor, new powerful systemic agents should be explored.…”
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Computational Study of Trisindoline 5 Against Overexpressed EGFR Protein on Breast Cancer Stem Cell by Nurhayati A.P.D., Fatoni M., Santoso M., Wati F.A.

“…The current treatment to control the proliferation rate of breast cancer is still not optimal due to the presence of breast cancer stem cells (BCSCs) which are resistant to several chemotherapy agents. Epidermal Growth Factor Receptor (EGFR) may promote the survival of BCSCs. …”
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Enabling Semantic Technology Empowered Smart Spaces by Jussi Kiljander, Arto Ylisaukko-oja, Janne Takalo-Mattila, Matti Eteläperä, Juha-Pekka Soininen

“…In particular the paper describes (1) methods for utilizing semantic technologies with resource restricted-devices, (2) a solution for identifying real world objects in semantic technology empowered smart spaces, (3) a method for users to modify the behavior of context-aware smart space applications, and (4) an approach for content sharing between autonomous smart space agents. The proposed solutions include ontologies, system models, and guidelines for building smart spaces with the M3 semantic information sharing platform. …”
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MINIMUM INHIBITORY CONCENTRATION OF PURPLE LEAF EXTRACT (GRAPTOPHYLLUM PICTUM L. GRIFF) AGAINST LACTOBACILLUS ACIDOPHILUS ATCC 4356 by Shafira Indriyani Chusnadia, Atik Kurniawati, Sari Setyaningsih, Erawati Wulandari, Pudji Astuti

“…Control of bacteria in the form of antibacterial agents is needed to suppress the growth of L. acidophilus. …”
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Prevention and management of cytomegalovirus infection and disease in kidney transplant: A consensus statement of the Transplantation Society of Taiwan by Mu-Chi Chung, Cheng-Hsu Chen, Shen-Shin Chang, Chih-Yuan Lee, Ya-Chung Tian, Mei-Yi Wu, Hsu-Han Wang, Chia-Cheng Yu, Teng-Wei Chen, Chien-Chang Kao, Chih-Yang Hsu, Yang-Jen Chiang, Ming-Ju Wu, Yen-Ta Chen, Mai-Szu Wu

“…Letermovir and marabavir are emerging CMV agents used for prophylaxis and refractory CMV disease. …”
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