Research Progress in Biological Characteristics of Fructilactobacillus sanfranciscensis and Its Influence on Fermented Pasta by Guohua ZHANG, Xiaxia HE, Ting LU, Tian SUN, Canlan WANG, Shiwei ZHOU

“…This review aims to explore the potential of the application of F. sanfranciscensis in sourdoughs for developing standardized sourdough fermentation agents and providing a theoretical basis for the industrialization of traditional fermented pasta.…”
Get full text

Three anti-inflammatory polysaccharides from Lonicera japonica Thunb.: insights into the structure-function relationships by Yu Liu, Hongjing Dong, Dongxiao Sun-Waterhouse, Wenwen Li, Bin Zhang, Jinqian Yu, Zhichang Qiu, Zhenjia Zheng

“…Thus, honeysuckle flowers are good sources of anti-inflammatory polysaccharides, and precise fractionation enables the production of potent anti-inflammatory agents for the development of functional foods and healthcare products.…”
Get full text

Inhibition of AKT enhances chemotherapy efficacy and synergistically interacts with targeting of the Inhibitor of apoptosis proteins in oesophageal adenocarcinoma by Leanne Stevenson, Lauren Cairns, Xiaodun Li, Sriganesh Jammula, Harriet Taylor, Rosalie Douglas, Niamh McCabe, Gerald Gavory, Xavier Jacq, Rebecca C. Fitzgerald, Richard D. Kennedy, Timothy Harrison, Richard C. Turkington

“…Hyperactivation of the PI3K-AKT-mTOR pathway is a common occurrence in OAC, driving cell survival, proliferation and resistance to chemotherapeutic agents. Inhibition of AKT has been explored as a treatment strategy with limited success and current inhibitors have failed to progress through clinical trials. …”
Get full text

Prevalence of Antimicrobial-Resistant Pathogens in Canadian Hospitals: Results of the Canadian Ward Surveillance Study (CANWARD 2007) by George G Zhanel, James A Karlowsky, Mel DeCorby, Kim A Nichol, Aleksandra Wierzbowski, Patricia J Baudry, Philippe Lagacé-Wiens, Andrew Walkty, Frank Schweizer, Heather Adam, Melissa McCracken, Michael R Mulvey, The Canadian Antimicrobial Resistance Alliance (CARA), Daryl J Hoban

“…With MRSA, no resistance was observed to daptomycin, linezolid, tigecycline and vancomycin, while resistance rates to other agents were: clarithromycin 91.4%, clindamycin 61.8%, fluoroquinolones 88.6% to 89.6%, and trimethoprim-sulfamethoxazole 12.2%. …”
Get full text

Percepción de estudiantes de Trabajo Social sobre derechos humanos en Chile by Cory Duarte Hidalgo, Alfredo García-Carmona, Alejandra Mora Castillo, Viviana Rodríguez Venegas

“…Durante la revuelta de octubre de 2019 se produjeron graves violaciones a los derechos humanos ejecutadas por agentes del Estado, las que en su mayoría no han tenido cierre judicial. …”
Get full text

Pharmacological activity of OST-01, a natural product from baccharis coridifolia, on breast cancer cells by HyunJun Kang, Dinh Hoa Hoang, Melissa Valerio, Khyatiben Pathak, William Graff, Alexis LeVee, Jun Wu, Mark A. LaBarge, David Frankhouser, Russell C. Rockne, Patrick Pirrotte, Bin Zhang, Joanne Mortimer, Le Xuan Truong Nguyen, Guido Marcucci

“…Abstract Natural products have long been a viable source of therapeutic agents, providing unique structures and mechanisms that may be beneficial for cancer treatment. …”
Get full text

Preparation and Antibacterial Properties of Substituted 1,2,4-Triazoles by Ionuţ Ledeţi, Vasile Bercean, Anda Alexa, Codruţa Şoica, Lenuţa-Maria Şuta, Cristina Dehelean, Cristina Trandafirescu, Delia Muntean, Monica Licker, Adriana Fuliaş

“…The evaluation of biological activities showed that the compounds act as antibacterial agents against Staphylococcus aureus (ATCC 25923), while being inactive against Escherichia coli (ATCC 25922) and Pseudomonas aeruginosa (ATCC 27853). …”
Get full text

Hybrid hydrogels containing gradients in gold nanoparticles for localized delivery of mesenchymal stem cells and enhanced nerve tissues remodeling in vivo by Jie Gao, Yiduo Zhou, Gang Xu, Zhongqing Wei, Liucheng Ding, Wei Zhang, Yi Huang

“…Herein, firstly reported as specific ROS scavenging agents and paracrine stimulators, gold nanoparticles (GNPs) were incorporated in the chitosan/polyvinyl alcohol hydrogel networks. …”
Get full text

Passive Immunoprophylaxis for the Protection of the Mother and Her Baby: Insights from In Vivo Models of Antibody Transport by Yanqun Xu, Iftekhar Mahmood, Lilin Zhong, Pei Zhang, Evi B. Struble

“…Vertical transmission of infectious agents, such as Zika, hepatitis B, and cytomegalovirus during pregnancy, remains a public health problem, associated with dire outcomes for the neonate. …”
Get full text

Contribution of Statins towards Periodontal Treatment: A Review by Catherine Petit, Fareeha Batool, Isaac Maximiliano Bugueno, Pascale Schwinté, Nadia Benkirane-Jessel, Olivier Huck

“…Moreover, combination of statin therapy with other regenerative agents improves periodontal healing response. Therefore, statins could be proposed as a potential adjuvant to periodontal therapy. …”
Get full text

Mesenchymal Stem/Stromal Cells from Discarded Neonatal Sternal Tissue: In Vitro Characterization and Angiogenic Properties by Shuyun Wang, Lakshmi Mundada, Eric Colomb, Richard G. Ohye, Ming-Sing Si

“…Autologous and nonautologous bone marrow mesenchymal stem/stromal cells (MSCs) are being evaluated as proangiogenic agents for ischemic and vascular disease in adults but not in children. …”
Get full text

Protective Effect of Baccharis trimera Extract on Acute Hepatic Injury in a Model of Inflammation Induced by Acetaminophen by Bruno da Cruz Pádua, Joamyr Victor Rossoni Júnior, Cíntia Lopes de Brito Magalhães, Míriam Martins Chaves, Marcelo Eustáquio Silva, Maria Lucia Pedrosa, Gustavo Henrique Bianco de Souza, Geraldo Célio Brandão, Ivanildes Vasconcelos Rodrigues, Wanderson Geraldo Lima, Daniela Caldeira Costa

“…When administered in high doses, APAP is a clinical problem in the US and Europe, often resulting in severe liver injury and potentially acute liver failure. Studies have demonstrated that antioxidants and anti-inflammatory agents effectively protect against the acute hepatotoxicity induced by APAP overdose. …”
Get full text

Managing pediatric psoriasis: update on treatments and challenges—a review by A. A. Hebert, J. Browning, P. C. Kwong, A. M. Duarte, H. N. Price, E. Siegfried

“…A growing number of clinical trials using biologic agents for pediatric psoriasis aim to broaden available treatment options but may also raise unique concerns associated with the use of these medications in children.Conclusion Pediatric psoriasis is underrecognized and often undertreated. …”
Get full text

Substituted piperazine conjugated to quinoline-thiosemicarbazide as potent α-glucosidase inhibitors to target hyperglycemia by Mehran Ghasemi, Mohammad Mahdavi, Maryam Dehghan, Mohammadreza Eftekharian, Somayeh Mojtabavi, Mohammad Ali Faramarzi, Aida Iraji, Ahmed Al-Harrasi

“…In this study, a series of thiosemicarbazide-linked quinoline-piperazine derivatives were synthesized and evaluated for their α-glucosidase inhibitory activity, to identify new agents for type 2 diabetes management. Structure-activity relationship (SAR) analysis revealed that the nature and position of substituents on the aryl ring significantly impacted the inhibitory potency. …”
Get full text

Demystifying E407 and E407a Additives (Carrageenans) Through Their Gastronomic Alchemy: A Contribution to Increase Consumer Sovereignty by Carla Matos, Manuela M. Moreira, Hélio Loureiro, Lígia Rebelo Gomes

“…This work reviews the physical/chemical properties of carrageenans, which are widely used as thickening and stabilizing agents in a wide range of everyday foods. This critical revision was made through bibliographic searches between January and May 2024 in the PubMed and Web of Science databases. …”
Get full text

Enhancing professional development for Third Space roles: reflections on the added value of Learning Circles by Linde Moriau, Réka Matolay, Emma McKenna, Andrea Toarniczky, Judit Gáspár, Márta Frigyik, Catherine Bates

“…We demonstrate that Learning Circles have the potential to create agentic, distributed, and adaptive professional learning spaces, enabling participating staff in reimagining their professional space, so that they feel better prepared to assume the hybrid roles and responsibilities that practices of engagement typically entail. …”
Get full text

Effect of Plantago major L. seed mucilage on physicochemical, rheological, textural and sensory properties of non-fat yogurt by Mojtaba Yousefi, Elham Khanniri, Nasim Khorshidian

“…Seed mucilages are water-soluble polysaccharides that can be used as gelling agents, stabilizers, emulsifiers, and coatings in the food industry. …”
Get full text

Microtissues in Cardiovascular Medicine: Regenerative Potential Based on a 3D Microenvironment by Julia Günter, Petra Wolint, Annina Bopp, Julia Steiger, Elena Cambria, Simon P. Hoerstrup, Maximilian Y. Emmert

“…Of great interest is the use of so-called microtissues or spheroids, which have evolved from their traditional role as in vitro models to their novel role as therapeutic agents. This review will provide an overview of the therapeutic potential of microtissues by addressing primarily cardiovascular regeneration. …”
Get full text

Endophytic fungi isolated from Vietnamese nut grass (Cyperus rotundus L. Cyperaceae) – A promising solution to mitigate the prime phenomenon of antibiotic resistance by Bac V.G. Nguyen, Linh X.T. Tran, Anh-Tu Ha-Nguyen, Minh-Tri Le, Thanh-Hoa Vo, Gia Phong Vu, Phuoc-Vinh Nguyen

“…., a common Asian medicinal herbal remedy, is gaining increasing attention in the scientific community as a potential source of antimicrobial agents. In this study, endophytic fungi living in this plant were isolated, macro- and micrologically identified, and assessed for their antibacterial properties on both Gram-positive and Gram-negative bacteria. …”
Get full text

The Caretaker: Cartografia de Afetos no Estado Demencial // The Caretaker: Cartography of Affections in the Demented State by Ana Rita Queiroz Ferraz, Iuri Cerqueira Moldes Morais

“…“Everywhere at the End of Time” é uma coletânea dividida em seis álbuns musicais, narrativamente denominados de estágios, com aproximadamente seis horas e meia de duração. …”
Get full text