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40061
Comparative phytochemical and pharmacological analysis of two cultivars of Annona squamosa L. cultivated in Egypt
Published 2025-01-01“…Overall, our findings indicate the potential for using active compounds of Annona squamosa L. cultivars to develop new therapeutic agents for cancer therapy and immune enhancement.…”
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40062
Targeting Herpetic Keratitis by Gene Therapy
Published 2012-01-01“…By November 2012, approximately 28 clinical trials were approved to assess novel gene therapy agents. Viral infections such as herpetic keratitis caused by herpes simplex virus 1 (HSV-1) can cause serious complications that may lead to blindness. …”
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40063
A Systematic Review of the Causes and Management of Ischaemic Stroke Caused by Nontissue Emboli
Published 2017-01-01“…We categorized the pathology of the emboli into the following groups: air embolism (141 reports), other arterial gas embolisms (49 reports), missiles and foreign bodies (16 reports), and others, including drug embolism, cotton wool, and vascular sclerosant agents. Conclusion. Air and gaseous embolism are becoming more common with increased use of interventional medical procedures and increased popularity of sports such as diving. …”
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40064
Successful Treatment of Fungal Dermatitis in a Bottlenose Dolphin (<i>Tursiops truncatus</i>)
Published 2025-01-01“…The co-administration of synergistic agents voriconazole and terbinafine, in conjunction with surgical debridement, successfully eliminated pheohyphomycosis and fusariomycosis in the bottlenose dolphin. …”
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40065
Investigating the effect of femtosecond laser pulses on noscapine and curcumin cellular uptake and improving drug delivery in gastric cancer cells
Published 2025-01-01“…The MKN45 cell line, a type of gastric cancer cell, exhibits resistance to chemotherapy agents through various mechanisms. Curcumin and noscapine, two plant-derived anticancer compounds, exhibit selective cytotoxicity towards cancer cells. …”
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40066
Genome sequence resources for three strains of the genus Clonostachys
Published 2025-01-01“…Several studies have reported Clonostachys fungi as effective biological agents against multiple fungal plant pathogens. To clarify the diversity and biocontrol mechanisms of the Clonostachys fungi, this study was undertaken to sequence and assemble the genomes of two C. chloroleuca and one C. rhizophaga. …”
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40067
The importance of pain assessment: The specifics of medical care
Published 2024-01-01“…However, the application of pharmacological agents to treat pain has to be carried out in collaboration with the doctor.…”
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40068
Green catalysts AuNPs/CQDs from turmeric starch: an effective solution in 4-Nitrophenol reduction
Published 2025-01-01“…The CQDs were then used as reducing agents and stabilizers to synthesize dual-shaped gold nanoparticles (AuNPs) with spherical and triangular shapes. …”
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40069
Some Bioactivities of Limonium meyeri Extracts and their Separated Compounds
Published 2025-01-01“…Apigenin-7-O-β-glucuronide and myricetin 3-O-α-rhamnoside were isolated from the ethyl acetate fraction using chromatographic methods. Methanol extract showed 62.0% and ethyl acetate extract showed 57.6% tyrosinase enzyme inhibition activities at 400 µg/mL concentration. …”
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40070
Allogeneic CD33-directed CAR-NKT cells for the treatment of bone marrow-resident myeloid malignancies
Published 2025-02-01“…Furthermore, CAR-NKT cells synergize with hypomethylating agents, enhancing tumor-killing efficacy. These cells also show minimal off-tumor toxicity, reduced graft-versus-host disease and cytokine release syndrome risks, and resistance to allorejection, highlighting their substantial therapeutic potential for treating myeloid malignancies.…”
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40071
Interaction between Bees and the Tristylous Flowers of Oxalis cytisoides Mart. & Zucc. (Oxalidaceae)
Published 2012-01-01“…The most frequent bees that carried O. cytisoides pollen grains on their bodies were considered pollinator agents, responsible for transferring pollen grains among the floral morphs.…”
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40072
Sesquiterpene Lactones as Promising Anti-Glioblastoma Drug Candidates Exerting Complex Effects on Glioblastoma Cell Viability and Proneural–Mesenchymal Transition
Published 2025-01-01“…Sesquiterpene triterpenoids (STLs) and their semi-synthetic analogs are considered as a promising source of novel anti-tumor agents due to their low systemic toxicity and multi-target pharmacological effects on key processes associated with tumor progression. …”
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40073
The chemokine CX3CL1 promotes intraperitoneal tumour growth despite enhanced T-cell recruitment in ovarian cancer
Published 2025-02-01“…T-cell recruiting chemokines are required for a successful immune intervention in ovarian cancer, and also for the efficacy of modern anticancer agents such as PARP inhibitors. The chemokine CX3CL1 recruits tumour-suppressive T-cells into solid tumours, but also mediates cell–cell adhesions, e.g. of tumour cells, through its membrane-bound form. …”
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40074
Mechanisms for Covalent Immobilization of Horseradish Peroxidase on Ion-Beam-Treated Polyethylene
Published 2012-01-01“…Appropriate blocking agents can block this reaction. All aminoacid residues can take part in the covalent attachment process, providing a universal mechanism of attachment for all proteins. …”
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40075
Phenazine biosynthesis-like domain-containing protein (PBLD) and Cedrelone promote antiviral immune response by activating NF-ĸB
Published 2025-01-01“…Consequently, our findings provide a potential combination model that targets PBLD for Cedrelone antiviral drug therapy, potentially paving the way for the development of broad-spectrum antiviral agents.…”
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40076
The Role of Women in Community Development: Reenacting Digital Activism in Improving Education for All Children, Lesson Learned from Tulungagung and Semarang
Published 2024-12-01“…This research seeks for the red thread of the role of women as agents in the development of community-based early learning methods, especially the implementation of digital literacy. …”
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40077
Unloading of Right Ventricle and Clinical Improvement after Ultrasound-Accelerated Thrombolysis in Patients with Submassive Pulmonary Embolism
Published 2014-01-01“…Acute pulmonary embolism (PE) can be devastating. …”
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40078
Severe Gingival Enlargement with Coexisting Erosive Lichen Planus in Severe Chronic Periodontitis Patient
Published 2015-01-01“…Gingival condition was also complicated by the presence of coexisting lichen planus which was predominantly erosive for which topical corticosteroid, antifungal, and antimicrobial agents were prescribed. Eight-month follow-up did not show recurrence of gingival enlargement. …”
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40079
Back-extraction of major actinides from organic phase through precipitation
Published 2024-09-01“…This work demonstrates the effectiveness of precipitation stripping using oxalic acid for the stripping of Th and U present in the organic phase, eliminating the need for reducing agents classically employed in the PUREX process.…”
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40080
Proteomic analysis of Trichoderma harzianum secretome and their role in the biosynthesis of zinc/iron oxide nanoparticles
Published 2025-01-01“…FTIR revealed organic compounds in nanoparticles acting as probably capping agents. This research is the first report in which a proteomic analysis identifies multiple enzymes involved in the biogenic process of NP biosynthesis from T. harzianum, and its role is clearly demonstrated by the formation of zincite and magnetite nanoparticles.…”
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