Essential Role of Thioredoxin 2 in Mitigating Oxidative Stress in Retinal Epithelial Cells by Eriko Sugano, Namie Murayama, Maki Takahashi, Kitako Tabata, Makoto Tamai, Hiroshi Tomita

“…We show that overexpression of Trx2 reduced cell death induced by both agents when they were present in low concentrations. …”
Get full text

Metemoglobinemia adquirida secundária à ingestão de alimento ultraprocessado em adolescente: um relato de caso by Camila Dalle Rocha, Ariadne Becker Quirino, Mariana Pinheiro Barbosa de Araújo, Mayanne de Fátima de Oliveira Barreto, Thays Taborda Damas, Francisco Carlos Yokoyama, Priscilla de Souza Prigol, Paulo Ramos David João

“…It is a congenital or acquired pathology, the latter when there is exposure to certain oxidizing agents, such as pesticides, fertilizers, topical anesthetics, and nitrates, as in the case described. …”
Get full text

Antimicrobial resistance and epidemiological patterns of Streptococcus pyogenes in Türkiye by Nihan Ünübol, Nese Caglayan, Sinan Cebeci, Yeşim Beşli, Banu Sancak, Neval Yurttutan Uyar, Siavosh Salmanzadeh Ahrabi, Masoud Alebouyeh, Tanıl Kocagöz

“…Background: Drug-resistant Group A beta-hemolytic streptococci remain significant infectious agents globally. This study investigated the major S. pyogenes strains responsible for infections in Türkiye and their susceptibility to beta-lactam and macrolide antibiotics. …”
Get full text

Risk Index Model of Property and Cargo Insurance Claims Based on Precipitation in Hunan by Peng Weiying, Li Yueyong, Tan Shiqi, Li Hao, Guan Jianwen, Liao Chunhua, Zhou Wei, Xie Ruiheng

“…The platform uses advanced intelligent grid precipitation forecasting data to produce timely alerts for precipitation risk and impact forecasts. …”
Get full text

Health Care Professionals and Data Scientists’ Perspectives on a Machine Learning System to Anticipate and Manage the Risk of Decompensation From Patients With Heart Failure: Quali... by Joana Seringa, Anna Hirata, Ana Rita Pedro, Rui Santana, Teresa Magalhães

“…Participants emphasized the need for a response model involving health care professionals to validate ML-generated alerts and determine appropriate interventions. …”
Get full text

Intracalvariosseous injection: an approach for central nervous system drug delivery through skull bone marrow with a preclinical research in strokeResearch in context by Wenqian Liu, Mo Yang, Nanxing Wang, Xiangrong Liu, Chaoyu Wang, Kaibin Shi, Fu-Dong Shi, Yuesong Pan, Mingjun Zhang, Zhiwei Sun, Yongjun Wang, Yilong Wang

“…In a rodent stroke model, NA-1 or Y-3 neuroprotective agents were administered via ICO to evaluate safety and efficacy by assessing neurological deficits, infarct size, neuroinflammatory factors, neuronal apoptosis, and liver/kidney function. …”
Get full text

Effect of Novel Biomodification Strategies on Bonding to Pulp Chamber Dentin – An In Vitro Study by Saranya Radhakrishnan, Darshana Devadiga

“…Conclusions: Dentin biomodification using both chemical and physical agents such as grape seed extract and diode LASER was shown to improve the shear bond strength of resin composite endodontic access restorations to the pulp chamber dentin.…”
Get full text

A regulação de conteúdo nas redes sociais: uma breve análise comparativa entre o NetzDG e a solução brasileira by Gabriel Ribeiro Brega

“…Nesse âmbito, almeja perquirir os reflexos de uma possível responsabilização de tais agentes pela sua recusa em excluir determinada publicação após receberem uma notificação que aponta para sua ilegalidade. …”
Get full text

Targeted Therapy on Age-Related Macular Degeneration by Vankodoth Sireesha, Kaluvala Ramya, Manne Nikshitha, Sunkari Nikitha, T. Rama Rao

“…Even though we have made good strides in spotting this disease for better treatment, we still need more research to really understand how it works to reduce disease conditions by various agents. This review article of AMD covers the recent trends in diseases, development of risk factors, diagnosis methods, grading system, and possibilities for AMD therapy.…”
Get full text

The Nasal Route as a Potential Pathway for Delivery of Erythropoietin in the Treatment of Acute Ischemic Stroke in Humans by Julio Cesar García-Rodríguez, Iliana Sosa Teste

“…Intranasal delivery provides a practical, noninvasive method of bypassing the blood-brain barrier (BBB) in order to deliver therapeutic agents to the brain. This method allows drugs that do not cross the BBB to be delivered to the central nervous system in a few minutes. …”
Get full text

Experimental Study of the Influence of the Adsorbate Layer Composition on the Wetting of Different Substrates with Water by Michaela Heier, Rolf Merz, Stefan Becker, Kai Langenbach, Michael Kopnarski, Hans Hasse

“…The samples were either exposed to an oil bath or not, and different cleaning agents were used. The analysis of the adsorbate layer was carried out with X-ray photoelectron spectroscopy (XPS). …”
Get full text

Dysregulation of the Autophagy-Endolysosomal System in Amyotrophic Lateral Sclerosis and Related Motor Neuron Diseases by Asako Otomo, Lei Pan, Shinji Hadano

“…The autophagy-endolysosomal pathway could be a major target for the development of therapeutic agents for ALS/MNDs.…”
Get full text

Digital Competences of Teachers in the Higher Education Academic Development System: Experience of the Empirical Research by A. V. Noskova, D. V. Goloukhova, E. I. Kuzmina, D. V. Galitskaya

“…A total of five focus groups of seven teachers in each were conducted.In the context of academic development, digital educational practices were analyzed, and three types of agents were identified – innovators and promoters, who contribute to the academic development of the higher education institutions, and routiners, who slow down the introduction of digital technologies. …”
Get full text

UMA ABORDAGEM PARA O MONITORAMENTO DE INDICADORES DE RESILIÊNCIA EM ORGANIZAÇÕES by Alan P. Souza, José O. Gomes, Paulo Victor R. de Carvalho

“…Esta pesquisa propõe aplicar os conceitos de engenharia de resiliência na compreensão da organização pela análise de tarefas e atividades cognitivas para o desenvolvimento de indicadores para avaliação das atividades pelos próprios agentes humanos atuantes no nível operacional, além da especificação inicial de uma ferramenta computacional para apoiar essa compreensão.…”
Get full text

Attenuation of Autoimmune Phenomena in a Patient with Autoimmune Polyglandular Syndrome Type 1 by Jill D. Jacobson, Julia R. Broussard, Courtney Marsh, Brandon Newell

“…We report on a girl whose disease was progressing rapidly until she began on immunosuppressive agents. A healthy 6-year-old girl with no remarkable medical history presented with new onset hypocalcemic seizures and primary hypoparathyroidism. …”
Get full text

Resistência e empoderamento na literatura urbana carioca by Rôssi Alves

“…Sin embargo, con el aumento de la represión y la necesidad cada vez mayor de otras formas públicas de recreación y cultura, los agentes involucrados en esta escena vienen sumando esfuerzos hacia una articulación con los órganos responsables del planeamento urbano, al mismo tiempo que éstos intentan promover manifestaciones que les den más visibilidad para validar sus políticas culturales en las calles. …”
Get full text

Instrumento para determinar los tipos de evaluación utilizados por los profesores universitarios by Arturo De la Orden Hoz, Julio Herminio Pimienta Prieto

“…Los resultados de este estudio aportan evidencia suficiente acerca de: 1) la validez de contenido del cuestionario, con un índice aceptable según los expertos (coeficiente alfa de Krippedorff mayor a 0.7); 2) La confiabilidad global del cuestionario equivalente a alfa=0.87 y la confiabilidad de las preguntas entre alfa 0.81 y alfa 0.87; 3) la validez de constructo del cuestionario; 4) la estructura factorial no se aparta significativamente de la teoría que ha servido de base para la especificación de las preguntas. …”
Get full text

¿A quién beneficia el comercio paralelo de medicamentos en la Unión Europea? by Joan Costa-Font, Panos Kanavos

“…En segundo lugar, establecemos una descomposición empírica de los efectos del comercio paralelo de medicamentos en los tres mercados principales de la Unión Europea en los diferentes agentes de la cadena del medicamento. Los resultados no siguieren pruebas de un efecto competitivo del comercio paralelo. …”
Get full text

Flocculation Settling Characteristics of Ultra-Fine Iron Tailings with Rich Gypsum by Daiqiang Deng, Guodong Cao

“…Hence, sedimentation tests using four types of flocculating agents are conducted to accelerate the sedimentation of the tailings of Chenchao Iron Mine. …”
Get full text

El fracaso del “Estado empresario”. La Dirección General de Fabricaciones Militares y el desarrollo de la metalurgia del cobre, 1941-1955 by Marcelo Rougier

“…El estudio revela las dificultades estructurales de la producción metalúrgica en la Argentina, en particular en lo que se refiere a la provisión de los insumos básicos, y las conflictivas relaciones que se establecieron con agentes del sector privado, quienes muchas veces juzgaron perniciosa la presencia de un competidor estatal en esa área. …”
Get full text