GENERAL JOB-EXCHANGES IN ROMANIA. A COMPARATIVE SPATIAL ANALYSIS OF VACANCY SUPPLY AND DEMAND BEFORE AND DURING THE CURRENT ECONOMIC – FINANCIAL CRISIS by IRENA MOCANU

“…Pendant cette crise, le nombre des agents économiques participants aux bourses générales d’emplois a enregistré uneévolution négative, à cause de la restreinte des activités économiques, avec des conséquences sur la croissance du surplus de force de travail. …”
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The Effects of Dipeptidyl Peptidase-4 Inhibitors on Cardiovascular Disease Risks in Type 2 Diabetes Mellitus by Pegah Yousefzadeh, Xiangbing Wang

“…The majority of the recent clinical studies have demonstrated that DPP-4 inhibitors have beneficial effects on cardiovascular (CV) system. These agents may have the potential to lower blood pressure, improve lipid profile and endothelial dysfunction, decrease the macrophage-mediated inflammatory response, and prevent myocardial injury. …”
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Probiotics in the Prevention and Treatment of Periodontal Diseases: A Systematic Review by Nishath Sayed Abdul, Lara Ghassan Odeh, Asma Awadh Alenazi, Jumana Abdullah Alzahrani, Aldanah Tawfiq Almutib, Cristalle Soman

“…Introduction: Periodontal diseases (PDs) pose a significant challenge to dental health, leading to a growing interest in probiotics as potential therapeutic and prophylactic agents. Literature evidence has shown conflicting results on the use of probiotics in the management of PDs. …”
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Growing together: unveiling the potential of school-based community gardens to foster well-being, empowerment, and sustainability by Tinashe Paul Kanosvamhira

“…By fortifying food security, propelling community development, and cultivating environmental sustainability, school-based gardens stand poised to be transformative agents, particularly within distressed neighborhoods of Cape Town. …”
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Antibiotics in the Treatment of Periodontitis: A Systematic Review of the Literature by Chaima Hammami, Wafa Nasri

“…The overall findings of this review show a positive effect of the use of antibiotics as an adjunctive to NSPT, regardless of the antimicrobial agents used in our included studies. Sites with PD > 6 mm may benefit most from the adjunctive use of antibiotics in NSPT. …”
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Sustainable Self-Healing Coatings: Optimizing Microencapsulation of Biodegradable Linseed and Hemp Seed Oils for Enhanced Corrosion Protection by Nazife Bengisu Sarıkaya, Merve Mocan

“…Corrosion is one of the biggest challenges in metal surfaces, especially when scratches and impacts damage the coating. Self-healing agents in the coating ensure long-term protection, effectively shielding the metal from corrosion. …”
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Biochemical Constituent of Ginkgo biloba (Seed) 80% Methanol Extract Inhibits Cholinesterase Enzymes in Javanese Medaka (Oryzias javanicus) Model by Ibrahim Hassan, Wan Norhamidah Wan Ibrahim, Ferdaus Mohamat Yusuf, Siti Aqlima Ahmad, Syahida Ahmad

“…Thus, the search for the alternative agents to replace synthetic drugs is in high demand. …”
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Development of a Novel Fluorescence Assay Based on the Use of the Thrombin-Binding Aptamer for the Detection of O6-Alkylguanine-DNA Alkyltransferase Activity by Maria Tintoré, Anna Aviñó, Federico M. Ruiz, Ramón Eritja, Carme Fàbrega

“…Human O6-alkylguanine-DNA alkyltransferase (hAGT) is a DNA repair protein that reverses the effects of alkylating agents by removing DNA adducts from the O6 position of guanine. …”
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The Genus <i>Chiliadenus</i>: A Comprehensive Review of Taxonomic Aspects, Traditional Uses, Phytochemistry and Pharmacological Activities by Lucinda Villaescusa Castillo, Francisco Zaragozá García, Cristina Zaragozá Arnáez

“…The findings show that the traditional therapeutic properties of <i>Chiliadenus</i> are well supported by reported pharmacological activities in previous studies, emphasizing the potential of this genus for the development of new therapeutic agents. However, the lack of comparative studies among <i>Chiliadenus</i> species and the scarcity of in vivo studies and clinical trials hinder the full realization of its therapeutic potential. …”
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The General Principle of the Warburg Effect as a Possible Approach for Cancer Immunotherapy: The Regulatory Effect of Plant Extracts Could Change the Game by Donika Ivanova, Severina Semkova, Boncho Grigorov, Milena Tzanova, Ana Georgieva, Dancho Danchev, Biliana Nikolova, Zvezdelina Yaneva

“…It is a well-known fact that the plant kingdom is a source of important therapeutic agents with multifaceted effectiveness. One of these is the known association with PPAR activities. …”
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Synthesis, characterization, and in silico studies of substituted 2,3-dihydro-1,3,4-thiadiazole derivatives by Yasser H. Zaki, Sobhi M. Gomha, Basant Farag, Magdi E.A. Zaki, Ahmed M. Hussein

“…These results, supported by ADMET studies, indicate that substituted 2,3-dihydro-1,3,4-thiadiazole scaffolds hold promise for further development as therapeutic agents. This research advances the understanding of heterocyclic chemistry and underscores the potential for developing new compounds, providing promising opportunities for drug development.…”
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Application of Ultrasound to Selectively Localize Nanodroplets for Targeted Imaging and Therapy by Paul A. Dayton, Shukui Zhao, Susannah H. Bloch, Pat Schumann, Kim Penrose, Terry O. Matsunaga, Reena Zutshi, Alexander Doinikov, Katherine W. Ferrara

“…Ultrasonic molecular imaging is unique in that the optimal application of these agents depends not only on the surface chemistry, but also on the applied US field, which can increase receptor-ligand binding and membrane fusion. …”
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The Visualization of Biofilms in Chronic Diabetic Foot Wounds Using Routine Diagnostic Microscopy Methods by Angela Oates, Frank L. Bowling, Andrew J. M. Boulton, Philip G. Bowler, Daniel G. Metcalf, Andrew J. McBain

“…Since biofilms are demonstrably less susceptible to antimicrobial agents than are planktonic bacteria, and may be present in chronic wounds, there is increasing interest in their aetiological role. …”
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Removal of U(VI) by Micrococcus aloeverae: condition, kinetic and mechanism studies by Xingming Gao, Mengmei Ye, Wenxin Li, Yong Lu, Lingzhi Bao

“…The ecological and environmental implications arising from the release of uranium during nuclear industry and mining activities are subject to considerable apprehension. Employing microbial agents for uranium remediation offers a promising and efficient alternative to tackle soil or wastewater contamination caused by uranium. …”
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Pediatric Ovarian Growing Teratoma Syndrome by Rebecca M. Rentea, Aaron Varghese, Atif Ahmed, Alexander Kats, Michelle Manalang, Tazim Dowlut-McElroy, Richard J. Hendrickson

“…The effect of chemotherapeutic agents for decreasing the volume of and prevention of expansion is unknown. …”
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PG102 Upregulates IL-37 through p38, ERK, and Smad3 Pathways in HaCaT Keratinocytes by Hyun-keun Kim, Seonung Lim, Min-Jung Bae, Wonwoo Lee, Sunyoung Kim

“…However, its role in keratinocytes has not been clearly understood, and there has been no report on the agents that can increase the expression of IL-37 in keratinocytes. …”
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Venoms and Extracellular Vesicles: A New Frontier in Venom Biology by Auwal A. Bala, Naoual Oukkache, Elda E. Sanchez, Montamas Suntravat, Jacob A. Galan

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Current and Future Perspectives of PD-1/PDL-1 Blockade in Cancer Immunotherapy by Rangarirai Makuku, Neda Khalili, Sepideh Razi, Mahsa Keshavarz-Fathi, Nima Rezaei

“…Among immunotherapeutic agents, immune checkpoint inhibitors have been of particular interest and have gained approval by the FDA for treatment of cancers. …”
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Telomere Biology: Key to unlocking the fountain of youth…A Systematic Review. by Anirban Poddar, Anup Kumar Rana, Ranjita Santra, Phalguni Chakrabarti

“…As the role of telomere biology is well established in ageing,current research therefore aims to develop means to reduce telomere attrition,thereby reducing ageing & age related diseases.This review will focus on summarising the role of telomere biology in ageing & age related diseases while highlighting the recent advances in research aiming towards enhanced longevity & healthy ageing.This review will further emphasize on telomere targetted therapeutics such as telomerase activators & tankyrase inhibitors while also highlighting the role of antioxidative & antiinflammatory agents alongwith indirectly related approaches such as statins.…”
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NOD Dendritic Cells Stimulated with Lactobacilli Preferentially Produce IL-10 versus IL-12 and Decrease Diabetes Incidence by Jean N. Manirarora, Sarah A. Parnell, Yoon-Hyeon Hu, Michele M. Kosiewicz, Pascale Alard

“…Evaluation of the relative production of IL-10 and IL-12 by DCs may be a very useful means of identifying agents that have therapeutic potential.…”
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