Improving polyketide biosynthesis by rescuing the translation of truncated mRNAs into functional polyketide synthase subunits by Yan Liu, Chaoyi Song, Qingwen Cui, Hongluan Sun, Chanjuan Jiang, Ruofei Guo, Ruoting He, Zhen Li, Ji Luan, Hailong Wang

“…Expression of the native and split busA genes in Streptomyces albus reveals that the majority ( >93%) of PKS mRNAs are truncated, resulting in a greater abundance of and a higher synthesis rate for the proteins encoded by genes closer to the operon promoter. …”
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A Rare Presentation of Checkpoint Inhibitor Induced Distal RTA by Andrew V. Doodnauth, Miriam M. Klar, Zohra R. Malik, Krunal H. Patel, Samy I. McFarlane

“…Common renal toxicity described includes acute interstitial nephritis, minimal change disease, and immune complex glomerulonephritis. …”
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Extending Shelf Life of Indonesian Soft Milk Cheese (Dangke) by Lactoperoxidase System and Lysozyme by Ahmad Ni’matullah Al-Baarri, Anang Mohamad Legowo, Septinika Kurnia Arum, Shigeru Hayakawa

“…This study was conducted to assess whether using lactoperoxidase system and lysozyme as preservative agents could suppress the growth of bacteria in dangke. …”
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Barcoded screening identifies nanocarriers for protein delivery to kidney by Luyao Wang, Wen Zhou, Hang Chen, Xiangqian Jia, Peiyuan Zheng, Haolin Jiang, Mengling Wu, Yaning Zhang, Yanchao Ding, Yexi Peng, Rui Zhu, Tiantian Li, Boxue Tian, Bujie Du, Juanjuan Du

“…The kidney-enriched nanocapsule successfully delivers catalase, showcasing its therapeutic potential in mitigating cisplatin-induced acute kidney injury. Overall, our study presents an approach for identifying protein delivery vehicles, with the capacity to broaden the application of proteins as therapeutic agents or research tools.…”
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La traversée d’un objet by Bruno Almosnino

“…Une tentative de fiction ébauchée, retrouvée dans les archives d’une synagogue, permet d’ajouter un nouvel élément à la longue liste des objets qui nous font agir dans le monde. …”
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Sensibilización a ácaros e inmunoglobulina E total en niños alérgicos by Nivia López Ramírez, Marisela L. Pérez Pacaréu, Vivian Macías Carrera, Andrés Osquel Benítez Goitizolo, Innery Rosell García, Isabel Vega Bolaño

“…Son los ácaros del polvo doméstico los principales agentes causales. La contaminación ambiental y los cambios climáticos, entre otros factores, han contribuido al incremento de estas enfermedades, dentro de las cuales las más frecuentes en pediatría son las alergias respiratorias y a su vez dentro de estas últimas la rinitis alérgica y el asma bronquial. …”
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Evaluation of Solubility and Complexation Ability of Vanillic, Syringic and Gallic Acids Towards Aluminum Cation by Donatella Aiello, Tiziana Marino, Anna Napoli, Emilia Furia, Pierluigi Plastina

“…Gallic acid forms more stable complexes with Al(III) ion than vanillic and syringic acids and could therefore represent a good candidate for being used as sequestering agents for Al(III) ion.…”
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Monitoring Detrusor Oxygenation and Hemodynamics Noninvasively during Dysfunctional Voiding by Andrew J. Macnab, Lynn S. Stothers, Babak Shadgan

“…However, as the function of the detrusor muscle depends on its vasculature and perfusion, the underlying causes of LUTS likely include abnormalities of detrusor oxygenation and hemodynamics, and available treatment options include agents thought to act on the detrusor smooth muscle and/or vasculature. …”
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Study of the Catalytic Activity and Surface Properties of Manganese-Zinc Ferrite Prepared from Used Batteries by Katarzyna Winiarska, Roman Klimkiewicz, Włodzimierz Tylus, Agnieszka Sobianowska-Turek, Juliusz Winiarski, Bogdan Szczygieł, Irena Szczygieł

“…Precursors of metal ions (Fe, Mn, and Zn) were obtained using different precipitating agents ((NH4)2C2O4, Na2CO3, and NaOH), and then, the combustion route was used to prepare catalytically active nanocrystalline ferrites. …”
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Calcium Channel Blocker Lacidipine Promotes Antitumor Immunity by Reprogramming Tryptophan Metabolism by Yuwen Sheng, Chong Qiao, Zhonghui Zhang, Xiaoke Shi, Linhan Yang, Ruiying Xi, Jialing Yu, Wanli Liu, Guolin Zhang, Fei Wang

“…Lacidipine activates effector T cells and incapacitates regulatory T cells (Tregs) to augment the anti‐tumor effect of chemotherapeutic agents in breast cancer by converting immunologically “cold” into “hot” tumors. …”
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Functional Ginger Extracts from Supercritical Fluid Carbon Dioxide Extraction via In Vitro and In Vivo Assays: Antioxidation, Antimicroorganism, and Mice Xenografts Models by Chih-Chen Lee, Li-Yu Chiou, Jheng-Yang Wang, Sin-You Chou, John Chi-Wei Lan, Tsi-Shu Huang, Kuo-Chuan Huang, Hui-Min Wang

“…To sum up, the data confirmed the possible applications as medical cosmetology agents, pharmaceutical antibiotics, and food supplements.…”
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Investigation of photophysical properties and potential biological applications of substituted tris(polypyridyl)ruthenium(II) complexes by T. Sumitha Celin, G. Allen Gnana Raj, T. S. Prathima, M. M. Balamurali

“…Herein, the potential applications of [Ru(bpy)3]2+ in clinical diagnostics as antioxidants and therapeutic agents were evaluated.…”
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Research Progress on Bacteriocins Produced by Lactic Acid Bacteria and Their Inhibitory Effect on the Biofilm of Staphylococcus aureus by Xiaoge XUE, Yuanyuan LIU, Lina ZHANG, Rui FAN, Yu XIN, Jiage MA, Wei YU, Libo LIU

“…This is expected to provide a scientific basis for the development and widespread application of LAB bacteriocins as biopreservative agents.…”
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Pseudotyped Viruses: A Useful Platform for Pre-Clinical Studies Conducted in a BSL-2 Laboratory Setting by Sofiia N. Rizatdinova, Alina E. Ershova, Irina V. Astrakhantseva

“…Such tools facilitated the search for potential therapeutic agents and accelerated epidemiological studies on post-infection and post-vaccination humoral immunity. …”
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Chitosan and Its Nanoparticles: A Multifaceted Approach to Antibacterial Applications by Emir Akdaşçi, Hatice Duman, Furkan Eker, Mikhael Bechelany, Sercan Karav

“…Over the course of the last several decades, chitosan nanoparticles (NPs), which are polymeric and bio-based, have garnered a great deal of interest as efficient antibacterial agents. This is mostly due to the fact that they are used in a wide variety of applications, including medical treatments, food, chemicals, and agricultural products. …”
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Vitamin A and its influence on tumour extracellular matrix by Guoqing Xie, Shun Cao, Guangchun Wang, Xianzhong Zhang, Yu Zhang, Haofan Wu, Shuxian Shen, Jiandong Le, Keqiang Li, Zhenlin Huang

“…The review highlights the potential of vitamin A and its derivatives as adjunctive agents in cancer therapy. Despite promising laboratory findings, their clinical application remains limited due to challenges in translating these effects into therapeutic outcomes. …”
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Anticancer Ribosomally Synthesized and Post-Translationally Modified Peptides from Plants: Structures, Therapeutic Potential, and Future Directions by Hyeon-Jeong Hwang, Youngsang Nam, Chanhee Jang, Eun La Kim, Eun Seo Jang, Yeo Jin Lee, Seoung Rak Lee

“…Cancer remains a significant medical challenge, necessitating the discovery of novel therapeutic agents. Ribosomally synthesized and post-translationally modified peptides (RiPPs) from plants have emerged as a promising source of anticancer compounds, offering unique structural diversity and potent biological activity. …”
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Polymeric Scaffolds in Tissue Engineering Application: A Review by Brahatheeswaran Dhandayuthapani, Yasuhiko Yoshida, Toru Maekawa, D. Sakthi Kumar

“…Various technologies come together to construct porous scaffolds to regenerate the tissues/organs and also for controlled and targeted release of bioactive agents in tissue engineering applications. In this paper, an overview of the different types of scaffolds with their material properties is discussed. …”
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Analisa Kesehatan Reproduksi Remaja Perempuan Usia Early Adolescence di Pekanbaru by Oswati Hasanah, Misrawati

“…Most respondents (63 %) have good habits in clothing, but more than a half have physiological vaginal discharge (55.6 %), almost all respondents have unhealthy habits in toiletting (97 %) and ever tried to overcome the flour albus (94.7 %) with a variety of herbs using traditional ingredients (79 %). …”
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Increased local DNA methylation disorder in AMLs with DNMT3A-destabilizing variants and its clinical implication by Dohoon Lee, Bonil Koo, Seokhyeon Kim, Jamin Byun, Junshik Hong, Dong-Yeop Shin, Choong-Hyun Sun, Jaesung Kim, Ji-Joon Song, Siddhartha Jaiswal, Sung-Soo Yoon, Sun Kim, Youngil Koh

“…Abstract The mechanistic link between the complex mutational landscape of de novo methyltransferase DNMT3A and the pathology of acute myeloid leukemia (AML) has not been clearly elucidated so far. …”
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