MPNs as Inflammatory Diseases: The Evidence, Consequences, and Perspectives by Hans Carl Hasselbalch, Mads Emil Bjørn

“…Early intervention with interferon-alpha2, which as monotherapy has been shown to be able to induce minimal residual disease, in combination with potent anti-inflammatory agents such as JAK-inhibitors is foreseen as the most promising new treatment modality in the years to come.…”
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Hemoglobin: A Nitric-Oxide Dioxygenase by Paul R. Gardner

“…NOD inhibitors are being pursued for therapeutic applications as antibiotics and antitumor agents. Transgenic NOD-expressing plants, fish, algae, and microbes are being developed for agriculture, aquaculture, and industry.…”
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MiRNAs as major players in brain health and disease: current knowledge and future perspectives by Sarika V. Kapplingattu, Sujata Bhattacharya, Yogita K. Adlakha

“…We highlight the promising therapeutic potential of miRNAs as antitumor agents for aggressive human brain tumors including glioblastoma.…”
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Constitucionalidade e convencionalidade da Lei de Anistia brasileira by Walter Claudius Rothenburg

“…Enquanto o STF considerou a lei compatível com a Constituição de 1988, a CIDH considerou-a incompatível com a Convenção Americana de Direitos Humanos, por entender que as graves violações a direitos humanos praticadas por agentes da ditadura não prescrevem e devem ser investigadas e punidas. …”
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Responsible finance: application and challenges for society, governments and corporations by V. I. Pyatanova, I. A. Pyatanov

“…Governments also have a role to play, as they support private initiatives and reconsider a huge variety of their projects to account for these additional factors that eventually impact population’s welfare. All economic agents should pay attention to this transformation to not miss out on the new standards of financial responsibility. …”
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Candidates for Bariatric Surgery: Morbidly Obese Patients with Pulmonary Dysfunction by Yu-Feng Wei, Huey-Dong Wu

“…Dietary modifications and pharmaceutical agents are not effective in the long-term treatment of obesity. …”
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Bacteria isolated from lungs of sheep with pneumonia and antibiotic susceptibilities by Dilek Öztürk, Mehmet Çorlu

“…A total of 150 lung samples from sheep with pneumonia was collected at Konya Meat and Fish Abottoir, A total of 60 bacterial agents was isolated from the 38 (25.33 %) of 150 sheep lung. …”
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Granulomatosis with Polyangiitis Presenting as Pauci-Immune Crescentic Glomerulonephritis in Pregnancy by Ryan Kunjal, Raafat Makary, Andreea Poenariu

“…Management initially comprised teratogen sparing agents; steroids, intravenous immunoglobulin; and plasma exchange. …”
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John of Salisbury’s Policraticus – Mirror of the Prince between Otium and Negotium by Oana-Corina Filip

“…Tratatul înlocuieşte vechile clasificări ale activităţilor în otium şi negotium şi adaugă o dimensiune etică, datorită căreia aceste categorii capătă atât forme corespunzătoare, cât şi necorespunzătoare. …”
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Routing in Vehicular Ad Hoc Networks: Main Characteristics and Tendencies by Joilson Alves Junior, Emilio C. G. Wille

“…Bioinspired routing protocols are based on the behavior of entities in the nature, and they are meant to work in a distributed mode, using mobile agents to find routes with specific features. In a parallel line of research, the differentiated behavior of urban transport vehicles suggests that a system that makes use of buses to create a communication infrastructure can perform better when compared to a system that does not distinguish between vehicles.…”
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Antoine Hennion: música, mediação e amadores by Paula Guerra, Marcílio Dantas Brandão, Alix Didier Sarrouy

“…Neste artigo, relevamos o posicionamento de Antoine Hennion, que defende que o ato de interpretação musical e o significado da música são inseparáveis do consumo de textos pelos públicos; trata-se, então, de dar ênfase interpretativa a um processo que é também subjetivo, onde os públicos surgem como agentes reflexivos e criativos. Esta linha de abordagem defendida por Hennion vai ser sustentada numa entrevista que o próprio autor concedeu no passado ano de 2015 quando da sua visita a Portugal, em atividades junto à Universidade do Porto. …”
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A aliança indissociável entre o turismo cultural e o turismo em espaço rural na Madeira by Elisabete Rodrigues

“…A metodologia incluiu, para além da pesquisa bibliográfica, a condução de inquéritos aos visitantes das «Casas de Campo» na Ilha, assim como de entrevistas semiestruturadas dirigidas aos proprietários/representantes destes empreendimentos. …”
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Mujeres detrás de la escena: Isabel Carrasquilla y Sofía Ospina de Navarro, dramaturgas al margen en la primera mitad del siglo XX en Colombia by Nancy Johana Correa Serna

“…Así mismo, sus producciones fueron identificadas con los denominados géneros menores: crónica, cuento y pequeñas obras teatrales, que se consideraban aceptables y propicias para las mujeres. Sin embargo, sus comedias presentan una visión renovada, y a veces transgredida, sobre los estereotipos de género de la época.…”
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Why women or why not men? sex and autoimmune diseases by Gilberto Cincinelli, Elena Generali, Rajkiran Dudam, Vinod Ravindran, Carlo Selmi

“…This enhanced reactivity may contribute to the stronger defense against infectious agents and to the reasons for which, on the other hand, women are more prone to develop autoimmune diseases. …”
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“O pescador é sofredor”: identidades e conflitos em torno da reprodução social da pesca artesanal na praia de Itapoã, Espírito Santo by Fanny Longa Romero

“…Por outro lado, indago os processos de transformação da pesca a partir de categorias como tempo e espaço, tal como essas noções são percebidas e ativadas nas experiências cotidianas dos agentes sociais. Os dados etnográficos resultam de trabalho de campo, em fase inicial, realizado na praia de Itapoã, em março de 2013. …”
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Los procesos de subjetividad y participación política de estudiantes de psicología de Bogotá by Martha Cecilia Lozano Ardila

“…Eel enfoque de la investigación fue de carácter histórico-hermenéutico a través del método narrativo, desde la perspectiva de Bruner (2002). concluyó que los procesos de subjetividad política de los jóvenes participantes en el estudio están mediados por la forma en que conciben la política y la participación en ésta y la influencia de agentes de socialización como la familia, los pares e incluso el Eestado.…”
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A review on the potential of Bruton’s tyrosine kinase (Btk) inhibitor – Ibrutinib for treatment of Multiple Myeloma (MM) by Sze-Ting Bong, Lydia Ngiik-Shiew Law, Jodi Woan-Fei Law

“…To date, clinical trials of ibrutinib as therapeutic alternative for MM have produced promising results, particularly as combination therapy with other agents such as dexamethasone and carfilzomib. However, there is limited evidence on the Btk mechanisms involved in MM, hence, it is important to further investigate the Btk oncogenic signalling pathway(s) in MM cells in order to establish successful and improved treatment of MM. …”
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Psoriasis: Unraveling Disease Mechanisms and Advancing Pharmacological and Nanotechnological Treatments by Miao M, Yan J, Sun Y, Liu J, Guo S

“…This review delves into the molecular underpinnings of psoriasis, examining current therapies and promising investigational agents. We highlight the potential of nanotechnology to enhance drug delivery to affected skin areas, with microneedles emerging as a promising platform for psoriasis and other chronic inflammatory skin diseases.Keywords: biodegradable nanoparticles, clinical trials, skin inflammatory diseases, psoriasis, microneedles…”
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La pesca y la caza marina en el desierto de Atacama: Luces conceptuales desde los documentos escritos (siglos XVI-XIX) by Benjamin Ballester

“…En este artículo discutimos las constantes confusiones que se generan en la definición de las categorías de captura marina, especialmente de pesca, caza y recolección, y proponemos una clasificación que considera la captura como una relación interespecie entre humano y animal, atendiendo las múltiples perspectivas y agentes involucrados. La propuesta se ejemplifica a partir de un caso de estudio, la sociedad litoral del desierto de Atacama entre los siglos XVI y XIX a través de la información contenida en los documentos escritos. …”
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deutetrabenazine for the treatment of chorea associated with Huntington’s disease by Harshit Gupta, Wil Perkins, Cain Stark, Sathya Kikkeri, Juyeon Kakazu, Adam D. Kaye, Alan D. Kaye

“…Thus, management is primarily focused on symptom management with the use of a variety of pharmaceutical agents. Chorea is one of the many manifestations that significantly alter the quality of life of many patients. …”
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