Fucofuroeckol-A from Eisenia bicyclis Inhibits Inflammation in Lipopolysaccharide-Induced Mouse Macrophages via Downregulation of the MAPK/NF-κB Signaling Pathway by Sang-Hoon Lee, Sung-Hwan Eom, Na-Young Yoon, Moon-Moo Kim, Yong-Xin Li, Sang Keun Ha, Se-Kwon Kim

“…Fucofuroeckol-A (FF) isolated from an edible perennial brown seaweed Eisenia bicyclis was shown to be potent anti-inflammatory agents. FF suppressed the production of nitric oxide (NO) and prostaglandin E2 (PGE2) and the expression of inducible nitric oxide synthase and cyclooxygenase-2 dose dependently in lipopolysaccharide- (LPS-) induced RAW 264.7 mouse macrophages. …”
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Radioresistance in rectal cancer: can nanoparticles turn the tide? by Diogo Coelho, Diogo Estêvão, Maria José Oliveira, Bruno Sarmento

“…Multifunctional nanomedicines offer a promising approach to improve radiotherapy response rates, as well as to increase the intratumoral concentration of chemotherapeutic agents, such as 5-Fluorouracil. Here, we revise the main molecular differences between rectal and colon tumors, exploring the complex orchestration beyond rectal cancer radioresistance and the most promising nanomedicines reported in the literature to improve neoadjuvant therapy response rates. …”
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Carbene-catalyzed chirality-controlled site-selective acylation of saccharides by Ying-Guo Liu, Zetao Zhong, Yuyang Tang, Hongling Wang, Sai Vikrama Chaitanya Vummaleti, Xi Peng, Peng Peng, Xinglong Zhang, Yonggui Robin Chi

“…Abstract Acylation stands as a fundamental process in both biological pathways and synthetic chemical reactions, with acylated saccharides and their derivatives holding diverse applications ranging from bioactive agents to synthetic building blocks. A longstanding objective in organic synthesis has been the site-selective acylation of saccharides without extensive pre-protection of alcohol units. …”
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Review of the clinical status of cardiotoxicity of HER-2 positive breast cancer targeted therapeutic drugs by Xiang Zhang, Yulian Yin, Qiuting Yu, Xinlin Chen, Yiqin Cheng

“…Targeted therapeutic agents, represented by trastuzumab, have been effective in improving the survival rate of HER-2-positive breast cancer patients. …”
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El rol del Estado en los países en desarrollo en la teoría evolucionista de Carlota Pérez. El caso del sector de software de Córdoba, Argentina by Carina Mariana Borrastero

“…Sugerimos que la autora mantiene una concepción restringida de los roles del Estado en los procesos de desarrollo, que dificulta la comprensión de los vínculos que dicho actor establece con los agentes privados. A partir de esta hipótesis analizamos la intervención estatal en el desarrollo del sector de software y servicios informáticos de Córdoba, Argentina, que muestra actualmente altos indicadores de desempeño significativamente marcados, desde nuestro punto de vista, por las características de dicha intervención. …”
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Analyzing the Responses of Enteric Bacteria to Neonatal Intensive Care Supplements by Megan E. Waller, Caroline J. Eichhorn, Alyssa Gutierrez, John E. Baatz, Carol L. Wagner, Katherine E. Chetta, Melinda A. Engevik

“…Human milk is typically fortified to meet increased calorie goals, and infants commonly receive vitamin mixes, iron supplements, and less frequently, thickening agents. We examined the growth of 16 commensal microbes and 10 pathobionts found in the premature infant gut and found that formula, freshly pasteurized milk, and donated banked milk generally increased bacterial growth. …”
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The role of MgO nanoparticles on the corrosion resistance of hot-dip Al–Zn coating by Seyed Reza Siasi Rad, Kamran Dehghani

“…By creating a protective shield and separating the coating from the corrosive agents, these nanoparticles enhanced the corrosion resistance of coatings. …”
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Up-to-Date Tailored Systemic Treatment in Pancreatic Ductal Adenocarcinoma by Caroline Y. K. Fong, Emma Burke, David Cunningham, Naureen Starling

“…Furthermore, it will explore newer approaches anticipated to come to the fore of future clinical practice, such as agents targeting the DNA damage response and tumour microenvironment as well as immunotherapy-based combinations.…”
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Endothelial Dysfunction and Diabetes: Effects on Angiogenesis, Vascular Remodeling, and Wound Healing by Gopi Krishna Kolluru, Shyamal C. Bir, Christopher G. Kevil

“…Many experimental studies have identified better approaches for diabetic cardiovascular complications, however, successful clinical translation has been limited possibly due to the narrow therapeutic targets of these agents or the lack of rigorous evaluation of pathology and therapeutic mechanisms in experimental models of disease. …”
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O círculo de conservação da natureza e regeneração no Tratado da conservação da saúde dos povos (1756) de Antônio Nunes Ribeiro Sanches by Ermelinda Moutinho Pataca

“…Buscamos compreender como o autor interpretou os processos naturais de formação da atmosfera terrestre, as relações entre os ambientes e os seres humanos e a consciência sobre a atuação do homem como agente geológico. Analisamos os sentidos construídos por Sanches sobre reparação natural inserida num círculo de conservação da natureza. …”
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Successful Treatment of Hepatitis C with Simeprevir, Sofosbuvir, and Ribavirin in an HIV Coinfected Liver Transplant Patient with Advanced Chronic Kidney Disease by Anna Maruyama, Trana Hussaini, Nilufar Partovi, Siegfried R. Erb, Vladimir Marquez Azalgara, Nadia Zalunardo, Neora Pick, Mark Hull, Eric M. Yoshida

“…The new DAAs show promise for HIV coinfected patients and those with severe to end-stage renal disease (ESRD); however, robust clinical trials or large cohort studies will need to be conducted to confirm the efficacy and safety of these newer agents in this setting.…”
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Modelli e specchi, mode e tendenze. Esercizi di decostruzione e ricostruzione per l’antropologia italiana by Francesco Faeta

“…A partire da una serrata analisi intorno alla legittimità contemporanea della nozione di antropologia italiana, l’autore esplora alcune delle caratteristiche ricorrenti di tale tradizione di studio, evidenziandone limiti e carenze, per delineare poi nuclei tematici caratterizzanti la specifica riflessione nazionale e indicare alcuni dei percorsi per uscire dalla crisi di credibilità complessiva da cui la disciplina sembra essere, al giorno d’oggi, afflitta. …”
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Diagnosis of Fanconi Anemia: Chromosomal Breakage Analysis by Anneke B. Oostra, Aggie W. M. Nieuwint, Hans Joenje, Johan P. de Winter

“…Cells derived from FA patients are—by definition—hypersensitive to DNA cross-linking agents, such as mitomycin C, diepoxybutane, or cisplatinum, which becomes manifest as excessive growth inhibition, cell cycle arrest, and chromosomal breakage upon cellular exposure to these drugs. …”
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Current status and future prospects of molecular imaging in targeting the tumor immune microenvironment by Xiang Wang, Xiang Wang, Weifen Shen, Weifen Shen, Lingjun Yao, Lingjun Yao, Chao Li, Chao Li, Huiming You, Huiming You, Duancheng Guo, Duancheng Guo

“…Additionally, the challenges faced by molecular imaging technologies are discussed, such as the need for highly sensitive and specific imaging agents, issues with data integration, and difficulties in clinical translation. …”
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Adulteration of the Herbal Weight Loss Products by the Illegal Addition of Synthetic Antiobesity Medications: A Pilot Study by Farzin Firozian, Amir Nili-Ahmadabadi, Shirin Moradkhani, Miad Moulaei, Zohreh Fasihi, Davoud Ahmadimoghaddam

“…Background. Some anorexic agents are used to fraudulent augmentation herbal weight loss formulations. …”
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Enhancing Islamic Religious Learning and Quranic Reading Through KKN-Thematic Program: A Case Study in Ridan Permai Village by Fakhrurrozi Pardosi, Sopian Sinaga, Dasa Syawal Syahputra, Dori Chandra, Candra Gunawan, Zulham Effendi, Ilham Tumanggor

“…Results show significant improvements in children's enthusiasm for Islamic studies and Quranic reading abilities following KKN-T student interventions through various learning activities such as Quran memorization and tahsin circles, Arabic language learning, prophetic biography studies, ablution and adhan practice training, and Islamic competitions. …”
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Evolution of the microbiota of wound infections in military personnel during the full-scale russian invasion: a retrospective cohort study (2022–2024) by N.A. Beley, O.A. Loskutov, A.M. Strokan, O.B. Izmaylova

“…The prevalence of infectious complications in blast injury reaches 35 %, and often the causative agents of such infections are multidrug-resistant microorganisms. …”
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Urbanizaciones cerradas en Mar del Plata: ordenamiento territorial y construcción social del espacio by Alejandro Maya

“…El análisis se reforzó con métodos de recopilación bibliográfica, trabajo de campo, estudios estadísticos, entrevistas a agentes privados y diseño de cartografía aplicada.…”
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Synthesis, characterization and biological profile of some new dihydropyrimidinone derivaties by Madiha Kanwal, Humaira Nadeem, Sumra Malik, Saima Maqsood

“…New dihydropyrimidinone derivatives were developed as agents to combat drug resistance. The results of these studies showed that newly synthesized dihydropyrimidinone derivatives are remarkably effective not only as anti-biotic agents but also counter inflammation caused by carrageenan resulting from the activation of the Toll-like receptors (TLRs) signaling pathway along with the non-toxic effect. …”
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In Vitro Activities of Ceftobiprole and Doripenem Tested against Frequently Encountered Aerobic and Facultative Gram-Positive and Gram-Negative Bacterial Pathogens Isolated from Pa... by James A Karlowsky, Mel DeCorby, Daryl J Hoban, George G Zhanel

“…The current study demonstrated both ceftobiprole and doripenem to be promising broad-spectrum antibacterial agents.…”
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