CHIMERIC ANTIGEN RECEPTOR T CELLS FOR THE TREATMENT OF MULTIPLE MYELOMA by Ugo Testa, Elvira Pelosi, Germana Castelli

“…Despite this progress, the efficacy of CAR-T cells in MM is limited by the responsiveness of only a part of the treated patients, the relapse of other patients, the cost of the treatment and the diminished response in patients with prior exposure to anti-BCMA targeting agents. Ongoing clinical trials are evaluating the use of CAR-T cells at an earlier stage of MM disease and the use of CAR-T cells targeting other membrane antigens expressed on malignant plasma cells. …”
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The Contribution of the Airway Epithelial Cell to Host Defense by Frauke Stanke

“…This paper summarizes functional data that describes the effect of cytokines, chemokines, infectious agents, and inflammatory conditions on the ion transport properties of the epithelial cell and relates these key properties to the molecular pathology of cystic fibrosis. …”
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Sprawl urbano em Londrina e os desafios para o planejamento urbano by Maurício Polidoro, José Augusto de Lollo, Osvaldo Coelho Pereira Neto

“…The urban zoning has been increasingly used in favor of agents promiting an unequal urban space and a clear process of socio-spatial segregation, the formation of vacant land and property speculation. …”
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Discourse-level structuring of information in narrative:Signalling structural, interactional and cognitive shifts by Tuija Virtanen

“…Discourse-level structuring of information is explored in narrative in the light of three parameters subsumed under this umbrella notion: (i) the structural concepts of “theme-rheme”, connected to “position”; (ii) the interaction-oriented pair of concepts “topic-comment”, grounded in the notion of “aboutness”; and (iii) the cognitively motivated gradient from “given” to “new” information, related to interlocutors’ assumptions of their memory constraints as well as those of others. …”
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LA DESCRIPCIÓN PLATÓNICA DE LA PERCEPCIÓN TEETETO, 184-186 by Luis Gerena

“…Intentaré mostrar en este trabajo que, para Platón, cumplir con la premisa (I) requiere elaborar una explicación de la percepción en la que el proceso de percepción lo lleve a cabo un único agente, el cual, asimismo, es el encargado de otros procesos cognitivos distintos de la percepción -como juzgar- pero, además, de un proceso mediante el cual, para todo objeto sensible x, es posible tener conocimiento de x.…”
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Inverse Gas Chromatography in the Examination of Modified Highly Dispersed Silicas by A. Voelkel, A. Krysztafkiewicz, T. Grześkowiak

“…Highly dispersed silicas were modified with silane coupling agents to decrease their surface hydrophilicity. The modification procedure was optimized, e.g. by the change of the modifier amounts added. …”
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Induction of Oxidative Stress in Kidney by Emin Ozbek

“…Several systemic diseases such as hypertension, diabetes mellitus, and hypercholesterolemia; infection; antibiotics, chemotherapeutics, and radiocontrast agents; and environmental toxins, occupational chemicals, radiation, smoking, as well as alcohol consumption induce oxidative stress in kidney. …”
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Cancer stem cells in head and neck squamous cell carcinoma and its associated markers: A review by Lavanya Mallika, Mani Rajarathinam, Sundararajan Thangavel

“…The cells being triggered by the agents may be somatic (differentiated functional cell) or a normal stem cell with multipotency or even the transient proliferative cells derived from the stem cells. …”
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Regulatory framework, the US health system, and international health displacement by MARIO ALBERTO DE LA PUENTE PACHECO, DIANA CIFUENTES, HEIDY RICO FONTALVO, ALEXANDER MAURICIO CARABALLO PAYARES

“…Se encuentra que la desregulación de los agentes del sector salud ha provocado un aumento de los costes directos e indirectos con efectos muy perjudiciales para los pacientes. …”
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PREVENTION OF ONCOLOGICAL DISEASES AS THE BASIS OF INTERACTION OF ONCOLOGICAL SERVICE WITH PRIMARY LINK OF HEALTH CARE by L. M. Aleksandrova, V. V. Starinsky, A. D. Kaprin, Yu. V. Samsonov

“…More than half of the working age population of deaths in Russia falls on the disease from the group of preventable death, and a third — to preventable causes, depending on the primary and secondary prevention, quality of care, along with a high prevalence of behavioral risk factors (RF), demographic characteristics, marked medical and social reasons for the high mortality rate of the MN: late uptake of the population for health care, lack of alertness in oncology healthcare professionals, patients defects in routing.The leading factor in increasing life expectancy is prevention. …”
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Automatic priority analysis of emergency response systems using internet of things (IoT) and machine learning (ML) by Abu S.M. Mohsin, Shadab H. Choudhury, Munyem Ahammad Muyeed

“…This allowed users to engage with the system through an intuitive interface and obtain timely alerts and insights. The system provides dynamic visualisation and real-time tracking of emergency scenarios through the integration of geographical information systems (GIS) and the utilisation of cloud computing resources. …”
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Development and validation of a risk prediction model for acute kidney injury in coronary artery disease by Ming Ye, Chang Liu, Duo Yang, Hai Gao

Subjects: “…Acute Kidney Injury…”
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Organization of the regional cancer service to improve the detection of malignant new formations during the COVID-19 pandemic by S. V. Golubev, V. Yu. Startsev, Yu. V. Samsonov

“…To increase the detection of malignant neoplasms, it’s necessary to provide examination rooms in the districts of the MagO; drawing up a "map of contamination of the territory"; assessment of the conditions of human production activity and population density; introduction of the standard of examination of patients with cancer; increasing the alertness and qualifications of primary outpatient medical personnel.…”
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APAH: An autonomous IoT driven real-time monitoring system for Industrial wastewater by Nishant Chavhan, Resham Bhattad, Suyash Khot, Shubham Patil, Aditya Pawar, Tejasvi Pawar, Palomi Gawli

“…Automated valve controls and real-time alerts enable timely intervention, preventing contamination and ensuring compliance with environmental standards. …”
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Optimizing personalized psychological well-being interventions through digital phenotyping: results from a randomized non-clinical trial by Giulia Rocchi, Giulia Rocchi, Emanuela Vocaj, Simone Moawad, Alessandro Antonucci, Carlo Grigioni, Vincenzo Giuffrida, Joy Bordini

“…A clustering algorithm created a user profile and content recommendation system to provide personalized exercises based on users’ responses.ResultsFour distinct clusters of participants emerged, based on factors such as online alerts, social media use, insomnia, attention and energy levels. …”
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Wearable Regionally Trained AI-Enabled Bruxism-Detection System by Anusha Ishtiaq, Jahanzeb Gul, Zia Mohy Ud Din, Azhar Imran, Khalil El Hindi

“…Bruxers require a gadget that not only identifies and continually monitors their bruxism activity, but also alerts them. In this study, a wearable EMG-based device has been designed to monitor and detect jaw clenching in the supine position using EMG of the two facial muscles, Temporalis and Masseter. …”
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Violence Detection From Industrial Surveillance Videos Using Deep Learning by Hamza Khan, Xiaohong Yuan, Letu Qingge, Kaushik Roy

“…The classifier’s predictions trigger real-time alerts, enabling rapid intervention. The modularity of this stage supports adaptability to new datasets, as it can leverage transfer learning to generalize across diverse surveillance contexts. …”
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A Seizure Attributed to Ofloxacine in a Woman Undergoing Detoxification for Alcohol Dependence by Pierre Lahmek, Laurent Michel, Nadine Meunier, Henri-Jean Aubin

“…Conclusions. The present case alerts us to the possibility that seizures may occur in alcohol dependent patients treated with benzodiazepines who concomitantly prescribed a fluoroquinolone. …”
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Ocurrencia del hongo Fusarium solani como patógeno causante de la muerte regresiva en el cultivo del aguacate by Nelsi Hermilia Chavez-Huaman, Pedro Vega y Montecillo, Luisa Madolyn Álvarez Benaute, Manuel Jorge Castillo Nole, Miltao Edelio Campos Albornoz, Agustina Valverde-Rodríguez

“…Los hallazgos permitieron identificar como el patógeno responsable de la muerte regresiva al hongo Fusarium solani. La confirmación del agente fitopatógeno se efectuó a través del reporte del Servicio Nacional de Sanidad Agraria. …”
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Hypophyseal Involvement in Immunoglobulin G4-Related Disease: A Retrospective Study from a Single Tertiary Center by Yang Liu, Linjie Wang, Wen Zhang, Hui Pan, Hongbo Yang, Kan Deng, Lin Lu, Yong Yao, Shi Chen, Xiaofeng Chai, Feng Feng, Hui You, Zimeng Jin, Huijuan Zhu

“…For patients with a longer history, the combination of GC and immunosuppressive agents is favorable. Early and adequate courses of treatment are crucial for the management of IgG4-RH. …”
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