When molecular biology transforms clinical oncology: the EGFR journey in colorectal cancer by Pietro Paolo Vitiello, Nadia Saoudi González, Alberto Bardelli

“…The preclinical and clinical development of agents targeting epidermal growth factor receptor (EGFR) in colorectal cancer (CRC) were accompanied by big hype and hopes, though the clinical testing of such agents clashed with intrinsic and acquired resistance, greatly limiting their therapeutic value. …”
Get full text

Understanding Insecticide Modes of Action and Resistance Management in Florida Horticulture by Hugh Smith, Adam Dale, Julien Beuzelin

“… This publication is designed to help UF IFAS Extension agents and members of the public understand insecticide modes of action and resistance management as they pertain to vegetables, field crops, turf, and ornamental plants. …”
Get full text

Additives in foods marketed to children in Uruguay, an emerging Latin American country by Florencia Alcaire, Ana Giménez, Gastón Ares

“…These products tended to more frequently notify colourings, antioxidants, acidity regulators, raising agents, stabilisers, humectants, anticaking agents, and glazing agents compared to products not marketed to children. …”
Get full text

Interim Report on Drug Utilization Review of Community Acquired, Nursing Home Acquired and Nosocomial Pneumonia: Clinical, Bacteriological and Radiological Spectrum by CW Chow, N Senathiragah, M Rawji, M Chan, LR Lee-Pack, CK Chan

“…OBJECTIVES: To review the epidemiology of community acquired, nursing home acquired and nosocomial pneumonia in terms of clinical. bacteriological and radiological features and to examine the spectrum of and response to antimicrobial agents used in its management.…”
Get full text

Laboratory Research on Fracture-Supported Shielding Temporary Plugging Drill-In Fluid for Fractured and Fracture-Pore Type Reservoirs by Dawei Liu, Yili Kang, Quanwen Liu, Dengsheng Lei, Bo Zhang

“…Theoretical and experiment studies conducted indicated that the FSDIF contained acid-soluble and non-acid-soluble temporary shielding agents; non-acid-soluble temporary shielding agents had high hardness and temporary plugging particles size was matched to the formation fracture width and pore throat size.…”
Get full text

Complexity Analysis for Price Competition of Agricultural Products with Regional Brands by Haolong Liu, Xin Su, Xiaohui Wang, Xiao Li

“…The disordered price competition among various agricultural business agents leads to chaos of agricultural products’ prices, which makes it difficult for customers to form stable price expectation and correct brand cognition, restricting the sales of agricultural products with regional brands. …”
Get full text

Efficacy of Venetoclax and Dexamethasone in Refractory IgM Primary Plasma Cell Leukemia with t(11;14) and TP53 Mutation: A Case Report and Literature Review by Salimah Valliani, Mir Ali, Omar Mahmoo, Sanjay Hinduja, Calvin K. Chen, Lloyd Damon, Haifaa Abdulhaq

“…He progressed on proteasome inhibitors, immunomodulating agents, and other chemotherapy medications but later achieved very good partial response (VGPR) to venetoclax and dexamethasone. …”
Get full text

Territórios da memória étnica e memórias étnicas de um território by Oswaldo Truzzi

“…São tomados como fontes os conteúdos de dois álbuns distintos – aqui entendidos como lugares de memória - produzidos nos anos de 1920. …”
Get full text

EVIDENCES OF DEFORMATIONS OF MINERALS OF THE BERKUT QUARTZ VEIN (SOUTH URALS) AFFECTED BY DYNAMOMETAMORPHIC PROCESSES by L.Ya. Kabanova

“…Dissolution and further deposition led to the crystallization of minerals of new generations (quartz, albite, and oligoclase) and often minerals of different composition (biotite after amphibole). …”
Get full text

Immune Response in Ovarian Cancer: How Is the Immune System Involved in Prognosis and Therapy: Potential for Treatment Utilization by Nikos G. Gavalas, Alexandra Karadimou, Meletios A. Dimopoulos, Aristotelis Bamias

“…Resistance to the disease occurs in more than 70% of the cases even after treated with chemotherapy agents such as paclitaxel- and platinum-based agents. …”
Get full text

Site-Specific Immunosuppression in Vascularized Composite Allotransplantation: Prospects and Potential by Jonas T. Schnider, Matthias Weinstock, Jan A. Plock, Mario G. Solari, Raman Venkataramanan, Xin Xiao Zheng, Vijay S. Gorantla

“…The skin is directly accessible for visual monitoring of acute rejection (AR) and for directed biopsy, timely therapeutic intervention, and management of AR. …”
Get full text

Impacto en la calidad de vida y bienestar emocional de pacientes con cáncer de próstata según el tratamiento recibido by Felipe Botero-Rodríguez, Liz M. Martínez-Torres, Laura A. Vivas-Restrepo, Lucía López-Paternostro, Jennifer Clavijo-Marín, Juan G. Cataño-Cataño

“…Describir y sintetizar la evidencia existente sobre el impacto en la calidad de vida y el bienestar emocional de los pacientes con cáncer de próstata según la intervención recibida. …”
Get full text

Behold the Man, again: What Nietzsche hopes his Readers will see in 'Ecce Homo' by Daniel Conway

“…The defiance displayed by Jesus at John 19:5 thus alerts us to the corre-sponding emergence of Nietzsche—as the "first immoralist"—from the morality he has outgrown. …”
Get full text

Auditory Stimulation Dishabituates Olfactory Responses via Noradrenergic Cortical Modulation by Jonathan J. Smith, Kiseko Shionoya, Regina M. Sullivan, Donald A. Wilson

“…These results provide a cortical mechanism for a return of habituated sensory responses following a cross-modal alerting stimulus.…”
Get full text

WEB-BASED SCORING APPLICATION FOR MONITORING AND EVALUATION OF HIGHER EDUCATION ACCREDITATION RANKING by Hasanuddin Hasanuddin, Andie Andie

“…The primary objective of the application is to recapitulate PEPA scoring and provide alerts to Study Programs when their scores fall below the required standards. …”
Get full text

Sports and Games Union Policy by Kabale University

“…Such values as untiring work ethic-hard work endurance , perseverance , discipline ,leadership, how to follow , communication commitment time management , reliability, sportsmanship , responsibility , confidence character, creativity , socialization, motivation unselfishness/teamwork, self-awareness and alertness, how to handle adversity of losses and how to accept winning and losing graciously , among many other values are what sports help to instill into the participating athlete.…”
Get full text

Situating complexity: information behaviour in the contact zone by Hye Lim Joy Nam

“…The contact zone is suggested as a critical lens to examine spatially bound interactions that could offer a more anchored, multi-agentic vision for researching information behaviour.…”
Get full text

La dependencia estatal en programas para jóvenes: ¿estigma o factor de protección? by Marina Medan

“…Enfocarse en la dimensión etaria de los jóvenes y las jóvenes y en el posicionamiento crítico de los agentes hacia el Estado, permite discutir la tradicional afirmación de que la dependencia solo se despliega peyorativamente. …”
Get full text

Gadolinium-Induced Acute Graft Pancreatitis in a Simultaneous Pancreas-Kidney Transplant Recipient by Chiang Sheng Lee, Rachel Yi Ping Tan, Nitesh N. Rao

“…Gadolinium-induced acute pancreatitis is a rare phenomenon associated with the administration of gadolinium-based contrast agents. …”
Get full text

Comparative Analysis of Nanoparticle-Antibody Conjugations: Carbodiimide Versus Click Chemistry by Daniel L.J. Thorek, ew R. Elias, Andrew Tsourkas

“…Typically, these applications involve functionalizing the nanoparticles with targeting agents. Antibodies remain an attractive choice as targeting agents because of their large epitope space and high affinity; however, implementation of antibody-nanoparticle conjugates is plagued by low coupling efficiencies and the high cost of reagents. …”
Get full text