Development of a core outcome set and core measurement set for kangaroo mother care: a study protocol by Yuan Li, Xia Li, Qiong Chen, Ying Xin Li, Han Mei Peng, Xue Mei Guo, Xiao Wen Li, Yan Ling Hu, Xing Li Wan

“…These discrepancies hinder the inclusion of KMC clinical research in systematic reviews or meta-analyses, reducing its research value, leading to resource wastage and raising concerns about selective reporting biases. A core outcome set (COS), which defines a list of critical outcomes, can help harmonise the outcomes reported across studies in the same healthcare field. …”
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Biomarker combinations from different modalities predict early disability accumulation in multiple sclerosis by Vinzenz Fleischer, Tobias Brummer, Muthuraman Muthuraman, Muthuraman Muthuraman, Falk Steffen, Milena Heldt, Maria Protopapa, Muriel Schraad, Gabriel Gonzalez-Escamilla, Sergiu Groppa, Stefan Bittner, Frauke Zipp

“…Finally, predictive causal modeling identified that LV mediates significant parts of the effect of GMV and sNfL on disability progression.ConclusionMultimodal biomarkers, i.e. different major surrogates for pathology derived from MRI, OCT and blood, inform about different parts of the disease pathology leading to clinical progression.…”
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Medium- to long-term health condition of patients post-COVID-19, exercise intolerance and potential mechanisms: A narrative review and perspective by Fabian Schwendinger, Denis Infanger, Debbie J Maurer, Thomas Radtke, Justin Carrard, Julia M Kröpfl, Aglaia Emmenegger, Henner Hanssen, Christoph Hauser, Udo Schwehr, Hans H Hirsch, Julijana Ivanisevic, Karoline Leuzinger, Aurélien E Martinez, Marc Maurer, Thomas Sigrist, Lukas Streese, Roland von Känel, Timo Hinrichs, Arno Schmidt-Trucksäss

“…Results: Using echocardiography, persistent cardiac involvement of the left ventricle was observed in a fraction of patients both hospitalized and non-hospitalized. …”
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Implementation of the seven steps of patient safety in primary healthcare by Nur Syarianingsih Syam, Linda Tri Maryuni, Siti Kurnia Widi Hastututi, Sely Aprianda Syah Putri

“…One of the quality management indicators is patient safety, the safety steps are building awareness of the value of patient safety, leading and supporting staff, integrating risk reporting activities, developing reporting systems, involving and communicating with patients, learning and sharing experiences about patient safety, and preventing injuries through the implementation of patient safety systems. …”
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Megagrazer loss drives complex landscape-scale biophysical cascades by Olli Hyvarinen, Mariska te Beest, Elizabeth le Roux, Graham I H Kerley, Robert Buitenwerf, Dave J Druce, Jiquan Chen, Linda Rapp, Joana Fernandes, Joris P G M Cromsigt

“…We currently know very little about the influence of wild animals on land surface albedo and the resulting climate forcing of these albedo changes. …”
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Sources of right to freedom of peaceful assembly by М. А. Sambor

“…Sources of the right to freedom of peaceful assembly in their retrospective dimension allow us to approach the understanding of the right to freedom of peaceful assembly, taking into account the historical peculiarities of the understanding of this right, conditioned by the historical stages of the development of humanity, statehood and legal ideas about human rights in general and the right to freedom of peaceful assembly in particular. …”
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Anti-Inflammatory and Healing Activity of the Hydroalcoholic Fruit Extract of Solanum diploconos (Mart.) Bohs by Larissa Benvenutti, Roberta Nunes, Ivonilce Venturi, Silvia Aparecida Ramos, Milena Fronza Broering, Fernanda Capitanio Goldoni, Sarah Eskelsen Pavan, Maria Verônica Dávila Pastor, Angela Malheiros, Nara Lins Meira Quintão, Elizabeth Soares Fernandes, José Roberto Santin

“…It also indicates its potential use as a healing agent. Finally, the absence of acute toxic and genotoxic effects reinforces its possible use as medicinal product.…”
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Germline BRCA testing in Denmark following invasive breast cancer: Progress since 2000 by Aleksandar M. Kostov, Maj-Britt Jensen, Bent Ejlertsen, Mads Thomassen, Caroline Maria Rossing, Inge S. Pedersen, Annabeth H. Petersen, Lise Lotte Christensen, Karin A.W. Wadt, Anne-Vibeke Lænkholm

“…Results: Test rates rose most significantly among patients aged under 40 years, increasing from 47% (2000–2005) to 88% (2012–2017), albeit with regional discrepancies. Test timing shifted in recent years, with most results within 6 months of BC diagnosis, primarily among the youngest patients. …”
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Light intensity-dependent arrestin switching for inactivation of a light-sensitive GPCR, bistable opsin by Baoguo Shen, Seiji Wada, Tomohiro Sugihara, Takashi Nagata, Haruka Nishioka, Emi Kawano-Yamashita, Takeaki Ozawa, Mitsumasa Koyanagi, Akihisa Terakita

“…The amount of visible light-sensitive active states (photoproducts) is crucial for generating color opponency, raising questions about how and what arrestins are involved in PP1 inactivation. …”
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The fibrosis-4 index and its association with carotid atherosclerosis in type 2 diabetes: a cross-sectional study in China by Ying Miao, Yu Wang, Qin Wan, Nanwei Tong

“…Abstract Background The medical community has long been concerned about the cardiovascular disease risk in patients with type 2 diabetes. …”
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Personality and help-seeking for psychological distress: a systematic review and meta-analysis by Anna Szücs, Anna Szücs, Anna Szücs, Rachel Hui Xin Lam, Wymann Shao Wen Tang, Lifan Zhou, Monica Lazarus, Andrea B. Maier, Andrea B. Maier, Andrea B. Maier, Jose M. Valderas, Jose M. Valderas, Jose M. Valderas

“…Meta-analyses on the Five Factor dimensions and help-seeking attitudes supported robust negative associations with neuroticism, as well as positive associations with agreeableness, albeit less reliably. Other personality traits mostly corroborated the above relationships, while also contributing new perspectives, such as help-seeking behavior’s negative associations with reality weakness and cynicism, and positive associations with abasement and rigidity.DiscussionFuture research should investigate help-seeking behavior using external observations and longitudinal designs. …”
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Study protocol for a pragmatic randomised controlled trial of comparing enhanced acceptance and commitment therapy plus (+) added to usual aftercare versus usual aftercare only, in... by Imran Khan, Stephanie J. C. Taylor, Clare Robinson, Elisavet Moschopoulou, Paul McCrone, Liam Bourke, Mohamed Thaha, Kamaldeep Bhui, Derek Rosario, Damien Ridge, Sheila Donovan, Ania Korszun, Paul Little, Adrienne Morgan, Olivier Quentin, Rebecca Roylance, Peter White, Trudie Chalder

“…Abstract  Background Two million people in the UK are living with or beyond cancer and a third of them report poor quality of life (QoL) due to problems such as fatigue, fear of cancer recurrence, and concerns about returning to work. We aimed to develop and evaluate an intervention based on acceptance and commitment therapy (ACT), suited to address the concerns of cancer survivors and in improving their QoL. …”
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Proposing a two-stage screening approach to distinguish between transient and enduring postnatal depressive symptoms: A prospective cohort study by Johanne Smith-Nielsen, Ida Egmose, Stephen Matthey, Maria Stougård, Sophie Reijman, Mette Skovgaard Væver

“…However, previous studies with antenatal samples indicate that positive screenings might reflect transient distress that resolves without intervention, raising concerns about over-pathologizing typical postnatal responses and inefficiencies in referral practices. …”
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Real-Life Data on the Efficacy of Canakinumab in Patients with Adult-Onset Still’s Disease by Antonio Vitale, Virginia Berlengiero, Jurgen Sota, Luisa Ciarcia, Nicola Ricco, Sara Barneschi, Mariam Mourabi, Giuseppe Lopalco, Chiara Marzo, Francesca Bellisai, Florenzo Iannone, Bruno Frediani, Luca Cantarini

“…However, real-life experience is focused on the use of anakinra, while data about canakinumab (CAN) are mainly based on case reports and small case series. …”
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Verification of a resetting protocol for an uncontrolled superconducting qubit by Ming Gong, Feihu Xu, Zheng-Da Li, Zizhu Wang, Yu-Zhe Zhang, Yulin Wu, Shaowei Li, Youwei Zhao, Shiyu Wang, Chen Zha, Hui Deng, Zhiguang Yan, Hao Rong, Futian Liang, Jin Lin, Yu Xu, Cheng Guo, Lihua Sun, Juno Clark, Cheng-Zhi Peng, Yu-Ao Chen, Xiaobo Zhu, Jian-Wei Pan

“…We also implemented 100 randomly chosen interactions and demonstrated an average success probability of 0.323 for $$\left|1\right\rangle$$ 1 and 0.292 for $$\left|-\right\rangle$$ − , and experimentally confirmed the nonzero probability of success for unknown interactions; the numerical simulated values are about 0.3. …”
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Etelcalcetide: What we know eight years since its approval by Pedro Freitas, Luciano Pereira

“…This narrative review aims to summarize the published data about etelcalcetide, focusing on biochemical, cardiovascular (CV) and bone endpoints, as well as adverse effects and all-cause mortality. …”
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Immunomodulatory and growth-promoting effects of Rauwolfia serpentina root powder in broiler chicks challenged with Salmonella Gallinarum by Yingyu Zhang, Hiba Rehman, Farina Khattak, Maryam Tariq, Bushra Nisar Khan, Sadia Chaman, Ayaesha Riaz, Muhammad Ovais Omer, Aqib Ali, Qamar un Nisa, Muhammad Muddassir Ali, Gulbeena Saleem

“…BackgroundAmid growing concern about antimicrobial resistance due to the irrational use of antibiotics in treating common poultry diseases, particularly Salmonella which is a foodborne pathogen in humans. …”
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Impact of Nutritional Support for Tuberculosis on Intermediate and Terminal Undernutrition and Treatment Outcomes (INSTITUT) study: a protocol for a quasi-experimental study to ass... by Dissou Affolabi, Chelsie Cintron, Madolyn Dauphinais, Attannon Arnauld Fiogbe, Mohammed Fall Dogo, Safiou Ate, Christine Adjonou, Kokou Agossou, Susie Jiaxing Pan, Marius Esse, Benjamin Ade, Komi Séraphin Adjoh, Pranay Sinha, Kobto G Koura

“…However, given ethical concerns, well-powered randomised control trials of macronutrient support are unavailable to inform policymakers, clinicians and researchers about the impact of nutritional support. However, there is potential to understand the impact of macronutrient nutritional support through a natural experiment. …”
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A Comparative Study of the Reasons for the Persistence of Buddhism and the Decline of Zoroastrianism in Ancient China by Amin Yazdkhasti, Hamidreza Pashazanous

“…The comparative study of these factors showed that all of these issues are true in a negative way about the failure and decline of Zoroastrianism in China.…”
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Mineralization and metallogenic model of the Laurani high-sulfidation epithermal deposit in northeastern Bolivian Altiplano by Fei Liu, Runsheng Han, Shuming Wen, Dong Zhao, Wenyao Li, Li Lei, Chaojian Qin, Yuxinyue Guo

“…Abstract The Laurani high-sulfidation epithermal deposit, located in the northeastern Altiplano of Bolivia, is a representative gold-polymetallic deposit linked to the late Miocene volcanic rocks that were formed approximately at about 7.5 Ma. At Laurani, four mineralization stages are defined. …”
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