Development of the early fetal human thalamus: from a protomap to emergent thalamic nuclei by Maznah Alhesain, Ayman Alzu’bi, Ayman Alzu’bi, Ayman Alzu’bi, Niveditha Sankar, Niveditha Sankar, Charles Smith, Charles Smith, Janet Kerwin, Ross Laws, Susan Lindsay, Gavin J. Clowry

“…IntroductionMost of what is known about thalamic development comes from rodent studies, however, the increased proportion of human association cortex has co-evolved with increased thalamocortical connectivity. …”
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The burden of generational harm due to alcohol use in Tanzania: A mixed method study of pregnant women. by Kirstin West, Alena Pauley, Mia Buono, Miriana Mikindo, Yvonne Sawe, Joseph Kilasara, Francis Sakita, Sharla Rent, Bariki Mchome, Blandina T Mmbaga, Catherine A Staton

“…Despite generally negative views of pregnant women who consume alcohol (PWCA), some sociocultural beliefs and limited knowledge about the dangers of prenatal alcohol exposure encouraged alcohol use during pregnancy. …”
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Perancangan Sistem Informasi Basis Data IKM Binaan Pada Dinas Perindustrian dan Perdagangan Provinsi Jawa Barat by Iman Sudirman, Atya Nur Aisha, Joe Monang, Taufan Fadhilah Iskandar

“…In general, the information system can be used by SMEs to report business profiles and propose facilitation needs by online and can be utilized by the Agency to view SME business profiles, obtain data about facilitation activities, analyze the progress of facilitation, and evaluate the facilitation that has been provided to SMEs based on the database in generated by the system. …”
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Human Adipose-Derived Mesenchymal Stem Cells Cryopreservation and Thawing Decrease α4-Integrin Expression by Ana Carolina Irioda, Rafael Cassilha, Larissa Zocche, Julio Cesar Francisco, Ricardo Correa Cunha, Priscila Elias Ferreira, Luiz Cesar Guarita-Souza, Reginaldo Justino Ferreira, Bassam Felipe Mogharbel, Venkata Naga Srikanth Garikipati, Daiany Souza, Mirian Perlingeiro Beltrame, Katherine Athayde Teixeira de Carvalho

“…The effects of cryopreservation on adipose tissue-derived mesenchymal stem cells are not clearly documented, as there is a growing body of evidence about the importance of adipose-derived mesenchymal stem cells for regenerative therapies. …”
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The Effects of Oral Semaglutide on Hepatic Fibrosis in Subjects with Type 2 Diabetes in Real-World Clinical Practice: A Post Hoc Analysis of the Sapporo-Oral SEMA Study by Hiroya Kitsunai, Yuka Shinozaki, Sho Furusawa, Naoyuki Kitao, Miki Ito, Hiroyoshi Kurihara, Chiho Oba-Yamamoto, Jun Takeuchi, Akinobu Nakamura, Yumi Takiyama, Hiroshi Nomoto

“…The efficacy of semaglutide in treating liver fibrosis was confirmed by the addition of, and switching from, existing agent groups. Furthermore, improvement in the FIB-4 index was significantly negatively correlated with the baseline FIB-4 index. …”
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A novel conjugated polymer synthesized via a noble metal-free catalyst in photothermal therapy of hepatocellular carcinoma mediated by second near-infrared (NIR-II) laser by Shengsheng Cui, Xinni Pan, Shanshan Fan, Cheng Cao, Yingao Jiao, Yanfei Fu, Jiaqi Niu, Shujin Lin, Jingmao Lao, Yanlei Liu

“…PPAPA exhibits a high photothermal conversion efficiency of 75.2 % under 1064 nm laser irradiation, comparable to the benchmark organic photothermal agent SWCNT. Notably, the synthesis of PPAPA avoids the use of noble metal catalysts, eliminating potential biotoxicity caused by residual catalysts and ensuring optimal photothermal stability and efficiency. …”
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Patients’ acceptability and implementation outcomes of a case management approach to encourage participation in colorectal cancer screening for people with schizophrenia: a qualita... by Tempei Miyaji, Yosuke Uchitomi, Hiroyuki Okada, Masatoshi Inagaki, Maiko Fujimori, Taichi Shimazu, Masaki Fujiwara, Masafumi Kodama, Ryuhei So, Takanori Matsushita, Yusaku Yoshimura, Shigeo Horii, Hirokazu Takahashi, Naoki Nakaya, Shiro Hinotsu, Keita Harada, Norihito Yamada, Yuto Yamada, Tsuyoshi Etoh

“…In addition, three out of six providers were included.Data collection and analysis Using a structured interview, the case manager asked participants about patient acceptability and the helpful components of the intervention. …”
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Resveratrol contributes to NK cell-mediated breast cancer cytotoxicity by upregulating ULBP2 through miR-17-5p downmodulation and activation of MINK1/JNK/c-Jun signaling by Bisha Ding, Jie Li, Jia-Lin Yan, Chun-Yan Jiang, Ling-Bo Qian, Jie Pan

“…This finding identifies RES as a potentially effective therapeutic agent for inhibiting BC progression and optimizing NK cell-based cancer immunotherapy.…”
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Colorectal carcinogenesis in the Lynch syndromes and familial adenomatous polyposis: trigger events and downstream consequences by Pål Møller, Aysel Ahadova, Matthias Kloor, Toni T. Seppälä, John Burn, Saskia Haupt, Finlay Macrae, Mev Dominguez-Valentin, Gabriela Möslein, Annika Lindblom, Lone sunde, Ingrid Winship, Gabriel Capella, Kevin Monahan, Daniel D. Buchanan, D. Gareth Evans, Eivind Hovig, Julian R. Sampson

“…In path_MLH1 and path_MSH2 carriers, second hits lead to the formation of microscopically detectable, microsatellite unstable (MSI) crypts, from which CRC develops in about half of carriers over their lifetime, often without progressing through a diagnosable adenoma stage. …”
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Development and Evaluation of an Immunochromatographic Strip and a Magnetic Chemiluminescence Immunoassay for Detection of <i>Porcine Circovirus Type 2</i> Antigen by Sirui Tao, Yu Duan, Yinhe Zha, Xiaxia Tong, Yulong He, Huapeng Feng, Jianhong Shu

“…<i>Porcine circovirus type 2</i> (PCV2) is the main and primary causative agent of Postweaning Multisystemic Wasting Syndrome (PMWS). …”
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Meta-analysis of Therapeutic Effect in Depression Treatment of Repetitive Transcranial Magnetic Stimulation Combined Paroxetine by Xinyi GUO, Guo YU, Xiaokuo HE

“…Objective:To evaluate the therapeutic effect of repetitive transcranial magnetic stimulation(TMS)combined with paroxetine in the treatment of depression, provide reference for the clinical treatment and related research of depression.Methods:We electronically searched databases, including CNKI Chinese Journal Full-text Database, Wanfang Database, VIP Database, PubMed, the Cochrane Library and EMbase, to collect randomized controlled trials(RCTs)about depression treated by repetitive TMS combined with paroxetine. …”
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Effect of Buyang Huanwu Decoction Foot Bath on Pulmonary Rehabilitation of Patients with Chronic Obstructive Pulmonary Disease at Stable Phase by HUANG Huirong, HAN Xueqi, LIU Qinyu, XUE Jialu, YU Zhenling, CHEN Bin, MIAO Shaofang, CHEN Shuifeng

“…After discarding the residue, the decoction was placed in a bucket, and foot bath was conducted when the temperature dropped to about 40 ℃. Foot bath required the water surface to be 10 cm above the ankle joint, twenty minutes per time, and once per day before going to bed, seven times per week, continuous treatment for two weeks. …”
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Qualitative evaluation of the Rehabilitation Exercise and psycholoGical support After COVID-19 InfectioN (REGAIN) randomised controlled trial (RCT): ‘you are not alone’ by Gordon McGregor, Susanne Finnegan, Martin Underwood, Joyce Yeung, James Mason, Peter Heine, Nigel Edwards, Julie Bruce, Kate Seers, Harbinder Kaur Sandhu, Helen Atherton, Sharisse Alleyne, Katie Booth, Ranjit Lall, Vivien P Nichols, Stuart Ennis, Scott McGuire, Rachel Potter, Jessica Smith, Chen Ji, Shilpa Patel, Henry Nwankwo, Kate Evans, Susie Hennings, Alastair Canaway, Grace Lobley, David Mcwilliams, Christina Jones, Emma Padfield, David Montgomery, Beatriz Lara, Becky Haley, Francesca Denton, Bartholomew Sheehan, Mariam Ratna, Elaine Fairbrother, Zoe Noakes, Bogdan Zutic, Lee Austin, Tom Forsyth, Anne Bush, Alan Bush, Patrick Sawdon, Jonathon Prosser, Lee Tompkins, Jonathon Guck, Danielle Hale, Juwairia Said, Georgie Ray, Rowena Williams, Gail Evans, Thillini Hettiarachchi, Abeesh Panicker

“…The themes from group exercise were: (1) monitoring and modification of the online exercise; (2) catering for differing abilities; (3) feeling safe and confident to exercise; (4) progression of fitness; (5) optimal timing in the recovery trajectory; (6) group effect; (7) initial apprehension about exercise group; (8) gauging exercise capabilities; (9) translating exercises into life; and (10) on-demand supplementary videos. …”
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Factors associated with the discontinuation of modern contraceptive methods among lactating women in nine West African high-fertility countries: findings of the most recent demogra... by Abou Coulibaly, Adama Baguiya, Denise Kpebo, Augustin Zango, Halima Tougri, Franck Garanet, Seni Kouanda

“…Conclusion To improve the retention of women using contraceptive, high-fertility rate countries need to focus on contraceptive education, communication about side effects, dissemination of family planning messages through the media, and regular monitoring of women taking contraceptives.…”
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The Role of Intravenous Selexipag in Managing PAH and Bridging Gaps in Oral Treatment: A Narrative Review by Goren S, Kidwai N, Aronow WS, Lanier GM

“…IV selexipag is administered twice daily through an infusion lasting about 80&nbsp;minutes and is intended for temporary use. …”
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Modalities for the treatment of primary open-angle glaucoma by Zh.G. Oganezova, S.V. Simonova

“…Russian Journal of Clinical Ophthalmology. 2019;19(3):159–162.</i> </p> <p> <b>About authors:</b> </p> <p> <i>¹Janna G.…”
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‘It is scary to pause treatment’: perspectives on HIV cure-related research and analytical treatment interruptions from women diagnosed during acute HIV in Durban, South Africa: Socio-Behavioral research by Deli Mthimkhulu, Krista L. Dong, Mzwakhe Wiseman Ngcobo, Deborah Mindry, Ayanda Zulu, Ntombifuthi Langa, Luyanda Maphalala, Vanessa Pillay, Maud Mthembu, Annie Miall, Whitney Tran, Ana Dillen, Fang Wan, Ali Ahmed, Jamila K. Stockman, Maryam Hussain, Thumbi Ndung’u, Karine Dubé

“…While women diagnosed during acute HIV supported pausing antiretroviral treatment (ART) during analytical treatment interruption (ATI) to advance HIV cure research, concerns about health risks and HIV-related stigma were significant barriers to enrollment. …”
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Costs of community-wide mass drug administration and school-based deworming for soil-transmitted helminths: evidence from a randomised controlled trial in Benin, India and Malawi by Judd Walson, ROBIN BAILEY, Katya Galactionova, Maitreyi Sahu, Samuel Paul Gideon, Saravanakumar Puthupalayam Kaliappan, Chloe Morozoff, Sitara Swarna Rao Ajjampur, Khumbo Kalua, Euripide Avokpaho, Moudachirou Ibikounle, Arianna Rubin Means, James Simwanza, Wongani Lungu, Parfait Houngbegnon, Adrian J F Luty, Rachel Pullan

“…We compared the costs of cMDA to SBD to inform decision-making about future updates to STH policy.Design We conducted activity-based microcosting of cMDA and SBD for 2 years in Benin, India and Malawi within an ongoing cMDA trial.Setting Field sites and collaborating research institutions.Primary and secondary outcomes We calculated total financial and opportunity costs and costs per treatment administered (unit costs in 2019 USD ($)) from the service provider perspective, including costs related to community drug distributors and other volunteers.Results On average, cMDA unit costs were more expensive than SBD in India ($1.17 vs $0.72) and Malawi ($2.26 vs $1.69), and comparable in Benin ($2.45 vs $2.47). cMDA was more expensive than SBD in part because most costs (~60%) were ‘supportive costs’ needed to deliver treatment with high coverage, such as additional supervision and electronic data capture. …”
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Policy brief: Optimising antimicrobial usage in paediatric inpatient hospital settings by J Cloete, M Karsas, T Chetty, A Pillay, M Archary, D Moore, T Reddy, Y Balakrishna, F Nakwa, R Lancaster, A Goga, P Jeena

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Sensory acceptability of buffalo meat compared to beef by Luis A. de la Cruz-Cruz, Cristian Larrondo-Cornejo, Patricia Roldán-Santiago, René Rodríguez-Florentino

“…However, it is vital to increase the information about buffalo meat characteristics (chemical, nutritional, sensory properties, and technological quality) and improve marketing channels that ensure the availability of buffalo products. …”
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