A multi-stakeholder collaborative approach to awareness, education and support needed in the haemophilia gene therapy patient journey – a report on insights from a European patient... by O’Mahony Brian, Fletcher Simon, Baarslag Manuel, Khair Kate, Breederveld Daan, Jansen Nathalie, Pembroke Luke, Pinachyan Karen, Sivasubramaniyam Sujan

“…A one-day patient advisory board was conducted with the aim of gaining insights on what education and support would enable PwH to have appropriate conversations with health care practitioners (HCPs) about gene therapy and participate in informed shared decision-making. …”
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Evaluasi SIMRS pada Manajemen Sumber Daya Manusia dengan Framework COBIT 5 by I Nyoman Angga Prabawa, I Made Oka Widyantara, Made Sudarma

“…The result shows that SIMRS implementation towards human resources management is at capability level 1 with a value of about 74%. Gap analysis of expected capabilities at capability level 3 provides recommendation improvements in order to increase the strategic plan for SDM management as well as SIMRS and Information Technology (IT) service. …”
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Hubungan Status Gizi Bayi dengan Pemberian ASI Ekslusif, Tingkat Pendidikan Ibu dan Status Ekonomi Keluarga di Wilayah Kerja Puskesmas Padang Pasir by Aisyah Nilakesuma, Yusri Dianne Jurnalis, Selfi Renita Rusjdi

“…The research has been conducted about the relationship between infant nutritional status with exclusive breastfeeding, mother educational status, and economic status of family in working area of Padang Pasir Health Care. …”
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Photochemistry Aspects of the Laser Pyrolysis Addressing the Preparation of Oxide Semiconductor Photocatalysts by R. Alexandrescu, I. Morjan, F. Dumitrache, M. Scarisoreanu, I. Soare, C. Fleaca, R. Birjega, E. Popovici, L. Gavrila, G. Prodan, V. Ciupina, G. Filoti, V. Kuncser, L. Vekas

“…High precursor concentration of the oxidizer was found to favor the prevalent anatase phase (about 90%) in the titania nanopowders.…”
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Exploring the Role of the Pharmacist in the Prevention and Management of Hypertensive Disorders in Pregnancy in Ashanti Region, Ghana by Pauline Boachie‐Ansah, Berko Panyin Anto, Afia Frimpomaa Asare Marfo, Edward Tieru Dassah, Morrison Asiamah, Ivan Eduku Mozu, Nana Ofori Adomako, Kwaku Gyamfi Oppong

“…Administration of pharmacotherapeutic agents is critical in the prevention and management of these disorders. …”
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An Age-Related Hearing Protection Locus on Chromosome 16 of BXD Strain Mice by Qing Yin Zheng, Lihong Kui, Fuyi Xu, Tihua Zheng, Bo Li, Melinda McCarty, Zehua Sun, Aizheng Zhang, Luying Liu, Athena Starlard-Davenport, Ruben Stepanyan, Bo Hua Hu, Lu Lu

“…However, little is known about gene variants that have the converse function—protective genes that confer strong resistance to hearing loss. …”
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Differential responses of root and leaf-associated microbiota to continuous monocultures by Hao-Ran Li, Xiang-Yu Zhang, Kai-Ling He, Xin Xu, Xin-Wen Chen, Yaseen Ullah, Ting-Ting Zhang, Yan Chen, Chuan-Chao Dai, Wei Zhang

“…In comparison, little is known about how leaf-associated microbiota respond to continuous monocultures. …”
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Transformation of NO in Combustion Gases by DC Corona by Oleksandr Molchanov, Kamil Krpec, Jiří Horák, Lenka Kuboňová, František Hopan, Jiří Ryšavý, Marcelina Bury

“…In positive corona, dispersed active species distribution led to more uniform NO conversion, while negative corona exhibited concentrated reaction zones with about 20% higher ozone production. The reactions involving O and OH radicals were more important in positive corona, whereas ozone-mediated oxidation dominated in negative corona. …”
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A machine learning model to predict the risk factors causing feelings of burnout and emotional exhaustion amongst nursing staff in South Africa by Maria Magdalena Van Zyl-Cillié, Jacoba H. Bührmann, Alwiena J. Blignaut, Derya Demirtas, Siedine K. Coetzee

“…Currently, little is known about the unique factors associated with burnout and emotional exhaustion among nurses in South Africa. …”
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Attitudes of nurses toward telenursing and influencing factors in resource-limited settings: Northwest Ethiopia 2022 by Fikadu Wake Butta, Biniyam Chaklu Tilahun, Berhanu Fikadie Endehabtu, Adamu Ambachew Shibabaw, Alex Ayenew Chereka, Ayenew Sisay Gebeyew, Mekides Molla Reda, Gemeda Wakgari Kitil, Teshome Demis Nimani

“…This study aims to understand how nurses feel about telenursing care and the factors related to it at a specialized teaching referral hospital in northwest Ethiopia.MethodWe conducted a cross-sectional study at a specialized teaching referral hospital, employing a simple random sampling technique to gather information from 423 nurses. …”
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Shorter versus longer durations of antibiotic treatment for patients with community-acquired pneumonia: a protocol for a systematic review and meta-analysis by Gordon Guyatt, Arnav Agarwal, Mark Loeb, John Basmaji, Ya Gao, Maryam Ghadimi, Layla Bakaa, Luis Enrique Colunga Lozano, Saad Asif, Aninditee Das

“…Eligible studies will compare durations with a minimum difference of two days of antibiotic therapy, irrespective of antibiotic agent, class, route, frequency or dosage, and will report on any patient-important outcome of benefit or harm. …”
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Formation and fate of freshwater on an ice floe in the Central Arctic by M. M. Smith, N. Fuchs, E. Salganik, D. K. Perovich, I. Raphael, M. A. Granskog, K. Schulz, M. D. Shupe, M. D. Shupe, M. Webster

“…For example, the range of values from the CESM2 climate model roughly encapsulate the observed total freshwater production, while storage in melt ponds is underestimated by about 50 %, suggesting pond drainage terms as a key process for investigation.…”
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Identifying pesticide mixtures at country-wide scale by Cairo, Milena, Monnet, Anne-Christine, Robin, Stéphane, Porcher, Emmanuelle, Fontaine, Colin

“…The consequences of such exposure are still poorly understood, first because of potentially strong synergistic effects, making cocktails effects not predictable from the effects of single compounds, but also because little is known about the actual exposure of organisms to pesticide mixtures in nature. …”
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A Case of Hypophosphatasia Started Enzyme Replacement Therapy Since Babyhood Stage by Tatsuya Akitomo, Noriko Niizato, Ami Kaneki, Masashi Ogawa, Taku Nishimura, Mariko Kametani, Momoko Usuda, Yuko Iwamoto, Chieko Mitsuhata, Ryota Nomura

“…Although enzyme replacement therapy with asfotase alfa was approved in 2015, there are few reports about the dental outcomes of this treatment. Case presentation: A 1-year-old girl referred to our hospital had already lost two primary teeth at the time of her initial visit. …”
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Assessing the physical activity training needs and preferences of community health workers in South Africa by Mark Stoutenberg, Blanca S. Noriega Esquives, Ruth G. St Fleur, Susanna S. Koen, Estelle D. Watson, Francia G. Portacio, Georgia Torres

“…However, little is known about CHW preferences and desires towards receiving PA training. …”
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Public insight into knee osteoarthritis: a cross-sectional study from the West Bank, Palestine by Haya Jebreen Mohammed Warasna, Bashar Yaser Hasan Awad, Mohamad A. Banat, Mohammad Yaser Hasan Awad, Ahmed Farid Gadelmawla, Jameel Suliman, Tarek A. Owais, Ahmad J. Warasna

“…Conclusion This study emphasizes the critical importance of raising awareness and knowledge about osteoarthritis within the Palestinian community. …”
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The relationship between thiamin, folic acid and cognitive function in a rat model of uremia by Yifei Lu, Chenqi Xu, Kewei Xie, Bingru Zhao, Minzhou Wang, Cheng Qian, Xuemei Chen, Leyi Gu, Wangshu Wu, Renhua Lu

“…We hypothesized that uremia brings about deficiency of thiamin and folic acid and causes CI by inducing oxidative stress. …”
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Within-species variation in the gut microbiome of medaka (Oryzias latipes) is driven by the interaction of light intensity and genetic background by Evangelista, Charlotte, Kamenova, Stefaniya, Diaz Pauli, Beatriz, Sandkjenn, Joakim, Vøllestad, Leif Asbjørn, Edeline, Eric, Trosvik, Pål, de Muinck, Eric Jacques

“…Given the growing evidence about the gut microbiomes importance to host health, more in-depth studies are required to fully understand the role of the microbiome in size-selected organisms and the possible ecosystem-level consequences. …”
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On-Demand Therapy with Proton Pump Inhibitors for Maintenance Treatment of Nonerosive Reflux Disease or Mild Erosive Esophagitis: A Systematic Review and Meta-Analysis by Zubair Khan, Yaseen Alastal, Muhammad Ali Khan, Mohammad Saud Khan, Basmah Khalil, Shreesh Shrestha, Faisal Kamal, Ali Nawras, Colin W. Howden

“…Proton pump inhibitors (PPIs) are widely used for the long-term management of gastroesophageal reflux disease (GERD). However, concerns about the cost and/or inconvenience of continuous maintenance PPI treatment have led to the evaluation of various alternative approaches. …”
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Treatment of Proximal Humeral Fractures in Older Patients During COVID-19 Pandemic in Germany by Sußiek J, Koeppe J, Fischhuber K, Iking J, Marschall U, Raschke MJ, Katthagen JC, Stolberg-Stolberg J

“…Julia Sußiek,1,* Jeanette Koeppe,2,3,* Karen Fischhuber,2,3 Janette Iking,1,3 Ursula Marschall,4 Michael J Raschke,1 J Christoph Katthagen,1,3 Josef Stolberg-Stolberg1,3 1Department of Trauma-, Hand- and Reconstructive Surgery, University Hospital Muenster, Muenster, Germany; 2Institute of Biostatistics and Clinical Research, University of Muenster, Muenster, Germany; 3Research Group “Mathematical Surgery”, University Hospital Muenster, University of Muenster, Muenster, Germany; 4Department of Medicine and Health Services Research, BARMER Health Insurance, Wuppertal, Germany*These authors contributed equally to this workCorrespondence: Josef Stolberg-Stolberg, Department of Trauma-, Hand- and Reconstructive Surgery, University Hospital Muenster, Albert-Schweitzer-Campus 1, Building W1, Muenster, 48149, Germany, Tel +49 251 83 59231, Email josef.stolberg-stolberg@ukmuenster.dePurpose: The COVID-19 pandemic had a severe influence on the entire health sector. …”
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