The Two Sides of Placebo Analgesia: Differential Functional Connectivity Reveals Mechanisms of Placebo Analgesic Response by Bush NJ, Cushnie AK, Boissoneault J, Aghabeigi S, Alexander C, Staud R, Robinson ME

“…Generalized psychophysiological interaction (gPPI) was used to assess the group differences in functional connectivity during painful stimulation compared to warmth stimulation.Results: About 68.5% showed a reduction in pain in the placebo condition with an average decrease of 30.3%. …”
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From pollution to sustainable environment: unlocking the role of energy intensity and renewable energy in highly pollutant nations by Zhi Zhen Zhou, Muhammad Shahid Hassan, Muhammad Ibrahim Saeed, Haider Mahmood, Rukhsana Kalim, Amira Houaneb

“…To address this critical challenge in highly pollutant nations, this research inquires about the role of Energy Intensity (EI) along with Renewable Energy Consumption (REC) and non-REC as controlling indicators in the carbon emissions’ model. …”
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Low dose ATG-Fresenius for GVHD prophylaxis: a comparative study with ATG-Thymoglobulin by Itai Falicovich, Boaz Nachmias, Shlomo Elias, Eran Zimran, Adir Shaulov, Polina Stepensky, Batia Avni, Sigal Grisariu

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A New Antibody–Cytokine Construct Targeting Natural Killer Cells: An Immunotherapeutic Approach to Chronic Lymphocytic Leukemia by Michela Flego, Mauro Andreotti, Francesca Romana Mauro, Maria Beatrice Arasi, Silvia Zamboni, Zuleika Michelini, Sara Pepe, Clementina Maria Galluzzo, Roberta Amici, Diego Moricoli, Chiara Mazzei, Alessandro Ascione, Alessandra Mallano

“…The preliminary data presented in this work suggest that IL15’s targeting of NK cells via scFvB1 potentiates the effects of IL15 and that scFvB1IL15 can be a useful agent for overcoming NK functional gaps and contribute to NK-cell-based immunotherapies.…”
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Identification and characterization of multiple novel viruses in fecal samples of cormorants by Li Ji, Li Ji, Ran Zhao, Yifei Pei, Yijie Sun, Xiaoyi Sun, Likai Ji, Xiaochun Wang, Yuwei Liu, Quan Shen, Shixing Yang, Yan Wang, Wen Zhang

“…There is limited knowledge about the other viruses that cormorants may carry and infect.MethodsIn this study, we employed viral metagenomics to identify novel viruses in the fecal samples collected from cormorants in Xiamen City, Fujian Province, China.ResultsTwo novel viruses were identified, including one novel picornavirus named Cormhepa01 and one novel avain hepevirus named CormhepaE. …”
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Assessment of Technology Readiness in Norwegian Older Adults With Long-Term Health Conditions Receiving Home Care Services: Cross-Sectional Questionnaire Study by Sverre Bergh, Jūratė Šaltytė Benth, Lisbeth Dyrendal Høgset, Britt Rydjord, Lars Kayser

“…The demographic differences between the 4 clusters may inform stakeholders about which older people need the most training and support to take advantage of digital health care services.…”
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Grouting Mechanism in Water-Bearing Fractured Rock Based on Two-Phase Flow by Bo Ren, Wenqiang Mu, Bingyou Jiang, Guofeng Yu, Lianchong Li, Tingshuang Wei, Yunchun Han, Diancai Xiao

“…When the single-hole grouting was carried out, the predetermined value can be achieved in the height range, but it was only about 15 m on the side because of the water flowing, which cannot meet the requirements. …”
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The use of kinematic photogrammetry and LiDAR for reconstruction of a unique object with extreme topography: a case study of Dutchman’s Cap, Baltic seacoast, Lithuania by Birutė Ruzgienė, Lina Kuklienė, Indrius Kuklys, Dainora Jankauskienė, Dainora Jankauskienė, Sérgio Lousada, Sérgio Lousada, Sérgio Lousada, Sérgio Lousada, Sérgio Lousada

“…Applying an appropriate way for generation of the reliable and accurate spatial models of surface with extreme topography, four data sets were processed: images gained with the camera, oriented horizontally; images gained with the camera tilted at about 50°; combining both image sets collected from camera; LiDAR data. …”
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The relationship of well-being, academic self-efficacy, and academic major satisfaction among part-time job students: A cross-sectional study by Phuoc-Thien NGUYEN, Hoai-Thang TO, Gia-Phuoc TRAN-THIEN, Thien-Ly DUONG-VO, Ky LUU, Ngoc-Han NGUYEN-THI, Vinh-Long TRAN-CHI

“…Discussion: Our findings provide more evidence about the relationship between mental health, academic self-efficacy, and academic major satisfaction. …”
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What are parents' preferences for Human Papillomavirus vaccination promotion messages and communication? Application of a discrete choice experiment to a French Caribbean setting by Frédérique G. E. Dorleans, Jonathan Sicsic, Valérie Henry, Isabelle Bonmarin, Gwladys Nadia Gbaguidi, Lucie Leon, Jocelyn Raude, Jacques Rosine, Judith E. Mueller

“…Across a series of nine hypothetical scenarios, participants were asked to decide to vaccinate or not and how certain they were about this choice. Scenarios differed by five attributes (diseases characteristics, vaccine safety, health professionals or institutions promoting vaccination, social conformity and optimal vaccination age). …”
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Early characterization and prediction of glioblastoma and brain metastasis treatment efficacy using medical imaging-based radiomics and artificial intelligence algorithms by Noémie N. Moreau, Noémie N. Moreau, Samuel Valable, Cyril Jaudet, Loïse Dessoude, Leleu Thomas, Romain Hérault, Romain Modzelewski, Romain Modzelewski, Dinu Stefan, Juliette Thariat, Juliette Thariat, Alexis Lechervy, Aurélien Corroyer-Dulmont, Aurélien Corroyer-Dulmont

“…Even with intensive treatment involving radiotherapy and surgery, which frequently leads to cognitive decline due to doses on healthy brain tissue, the median survival is 15 months for GBM and about 6 to 9 months for BM. Despite these treatments, GBM patients respond heterogeneously as do patients with BM. …”
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Pyrrolizine-5-carboxamides: Exploring the impact of various substituents on anti-inflammatory and anticancer activities by Gouda Ahmed M., Abdelazeem Ahmed H., Abdalla Ashraf N., Ahmed Muhammad

“…The (EZ)-7-cyano-6-((4-hydroxybenzylidene)amino)-N-(p-tolyl)-2,3-dihydro-1H-pyrrolizine-5-carboxamide (4b) and (EZ)-6-((4-chlorobenzylidene)-amino)-7-cyano-N-(p-tolyl)-2,3-dihydro-1H-pyrrolizine-5-carboxamide (5b) bearing the electron donating methyl group showed the highest anti-inflammatory activity while (EZ)-6-((4-chlorobenzylidene)amino)-7-cyano-N-phenyl-2,3-dihydro-1H-pyrrolizine-5-carboxamide (5a) was the most active analgesic agent. Cytotoxicity of the new compounds was evaluated against the MCF-7, A2780 and HT29 cancer cell lines using the MTT assay. …”
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Microplastics: A threat to Fetoplacental unit and Reproductive systems by Abass Toba Anifowoshe, Md Noor Akhtar, Abisola Majeed, Asem Sanjit Singh, Toyyibah Funmilayo Ismail, Upendra Nongthomba

“…Plastic pollution has become a pressing global environmental and public health challenge, raising significant concerns about its potential effects on human health. While extensive research has been conducted on micro- and nanoplastics (MNPs), there remains a critical gap in understanding how these plastic particles traverse the maternal-fetal interface and contribute to reproductive anomalies. …”
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Mechanism of triptolide regulating proliferation and apoptosis of hepatoma cells by inhibiting JAK/STAT pathway by Wang Guanglian, Zhu Zhenxin, Sun Zhengang, Yang Zhiqi

“…As an anti-liver cancer agent, TPL inhibits the proliferation of hepatocellular carcinoma cells and promotes apoptosis. …”
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Development of a patient reported outcome instrument for chronic sialadenitis by Fatemeh Ramazani, Amr Hamour, Caroline C. Jeffery, Vincent Biron, Yaser Alrajhi, Daniel O’Connell, David W. J. Côté

“…Clinicians report improved patient quality of life (QoL) following sialendoscopy assisted treatments, but there exist gaps in current literature about patient reported outcomes (PROs). PROs are outcome measures developed based on patient perceptions. …”
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miR-1233-3p Inhibits Angiopoietin-1-Induced Endothelial Cell Survival, Migration, and Differentiation by Veronica Sanchez, Sharon Harel, Anas Khalid Sa’ub, Dominique Mayaki, Sabah N. A. Hussain

“…To date, very little is known about the roles played by miRNAs in the signaling and angiogenesis promoted by the Ang-1–Tie-2 receptor axis. …”
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Co-design of “Baatcheet,” a peer-supported, web-based storytelling intervention for young people with common mental health problems in India by Pattie P. Gonsalves, Dhriti Mittal, Shruti Aluria, Aarushi Khan, Eshita Razdan, Priyambada Kashyap, Navvya Rahate, Manek D’Silva, Sonaksha Iyengar, Faith Gonsalves, Sweta Pal, Salik Ansari, Clio Berry, Daniel Michelson

“…Baatcheet uses an interactive storytelling website containing a repository of personal stories about young people’s experiences of depression and anxiety. …”
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Nerve Enlargement in Patients with INF2 Variants Causing Peripheral Neuropathy and Focal Segmental Glomerulosclerosis by Quynh Tran Thuy Huong, Linh Tran Nguyen Truc, Hiroko Ueda, Kenji Fukui, Koichiro Higasa, Yoshinori Sato, Shinichi Takeda, Motoshi Hattori, Hiroyasu Tsukaguchi

“…In general, nerve enlargement has been reported in 25% of the demyelinating CMT subtype (CMT1), while little is known about the CMT-DIE caused by INF2 variants. <b>Methods</b>: To characterize the peripheral nerve phenotype of INF2-related CMT, we studied the clinical course, imaging, histology, and germline genetic variants in two unrelated CMT-DIE patients. …”
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Natural Products as Sources of Antimalarial Drugs: Ethnobotanical and Ethnopharmacological Studies by Oluwole Solomon Oladeji, Abimbola Peter Oluyori, Deborah Temitope Bankole, Tokunbo Yemisi Afolabi

“…Malaria is one of the lethal diseases of man, contributing to about 17 million deaths annually, leading to sociocultural, economic, and health influences. …”
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Impact of Ozone Valley over the Tibetan Plateau on the South Asian High in CAM5 by Zhenkun Li, Hao Qin, Dong Guo, Shunwu Zhou, Ying Huang, Yucheng Su, Linwei Wang, Yang Sun

“…Adiabatic expansion and ascending movement mainly bring about temperature decrease in SAH after OVTP removal, but the thermodynamic process related to radiative heating offsets part of the cooling response.…”
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