Navigating the Collective: Nanoparticle-Assisted Identification of Leader Cancer Cells During Migration by Anastasia Alexandrova, Elizaveta Kontareva, Margarita Pustovalova, Sergey Leonov, Yulia Merkher

“…In our previous work, we revealed that tumor cells exhibiting high metastatic potential (MP) are more adept at encapsulating 100–200 nm nanoparticles than those with lower MP. …”
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DMAV in Drinking Water Activated NF-κB Signal Pathway and Increased TGF-β and IL-1β Expressions in Bladder Epithelial Cells of Rats by Siqi Cao, Shengnan Liu, Fei Wang, Jieyu Liu, Mengdan Li, Chen Wang, Shuhua Xi

“…Dimethylarsinic acid (DMAV) is the main product of arsenic methylation metabolism in vivo and is rat bladder carcinogen and tumor promoting agent. In this study, we measured the expressions of mRNA and proteins of NF-κB pathway members, IKKα, IKKβ, p65, and p50 in rat bladder epithelium by qRT-PCR and immunohistochemical analysis after rats received drinking water containing 100 and 200 ppm DMAV for 10 weeks. …”
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THE CURRENT STATE AND PROSPECTS OF REGULATION OF DIVORCE PROCEEDINGS: RUSSIAN AND FOREIGN PRACTICE by Yu. V. Zemtsova, Polina P. Nechaeva, Nadezhda N. Shanihina

“…Purpose – consider the transformation of the divorce process from the Soviet era to the present day, as well as to update information about the features of the divorce process within the framework of modern law. …”
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Osteogenesis from Dental Pulp Derived Stem Cells: A Novel Conditioned Medium Including Melatonin within a Mixture of Hyaluronic, Butyric, and Retinoic Acids by Margherita Maioli, Valentina Basoli, Sara Santaniello, Sara Cruciani, Alessandro Palmerio Delitala, Roberto Pinna, Egle Milia, Regina Grillari-Voglauer, Vania Fontani, Salvatore Rinaldi, Roberta Muggironi, Gianfranco Pigliaru, Carlo Ventura

“…Such response was also elicited by cell exposure to melatonin, a pleiotropic agent that recently emerged as a remarkable osteogenic inducer. …”
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The Thermosphere Is a Drag: The 2022 Starlink Incident and the Threat of Geomagnetic Storms to Low Earth Orbit Space Operations by T. E. Berger, M. Dominique, G. Lucas, M. Pilinski, V. Ray, R. Sewell, E. K. Sutton, J. P. Thayer, E. Thiemann

“…Abstract On 03 February 2022, SpaceX launched 49 Starlink satellites, 38 of which re‐entered the atmosphere on or about 07 February 2022 due to unexpectedly high atmospheric drag. …”
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Effects of dietary supplements Sargassum ilicifolium and Spirulina platensis on growth parameters, immunity and gene expression in juvenile Asian seabass (Lates calcarifer) by Majid Khanzadeh, Seyed Hossein Hoseinifar, Ashkan Zargari, Hien Van Doan

“…Six hundred juvenile Asian sea bass, weighing about 50 ± 2 g, were divided into five groups: a control group (CTRL) and groups receiving varying percentages of Sargassum ilicifolium and Spirulina platensis (1.5 %, 2 %, 2.5 %, and 3 %). …”
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Relationship Between ABO Blood Groups and Mental Disorders by Ajdacic-Gross V, Buadze A, Wagner EYN, Müller M, Seifritz E, Ranjbar S, Glaus J, Castelao E, Strippoli MPF, Vandeleur CL, Preisig M, von Känel R

“…In our study, we used data from a large Swiss population-based epidemiological cohort study to learn more about this connection. We examined the relationship between ABO blood groups and five major groups of mental disorders: neurodevelopmental, early onset anxiety, later onset anxiety, mood, and substance use disorders. …”
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Identification and characterization of mRNAs of receptor-like kinases MhyGSO1 and MhyGSO2 in flowering parasitic plant Monotropa hypopitys by A. V. Shchennikova, E. Z. Kochieva, A. V. Beletsky, M. A. Filyushin, O. A. Shulga, N. V. Ravin, K. G. Skryabin

“…In combination with known data about GSO1 and GSO2, it allowed us to assume the redundant activity of MhyGASSHO paralogues in signaling pathways, in particular, in response to exogenous sucrose and in development of reproductive organs and embryonic inflorescences.…”
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Decreased expression of miR-200a and miR-223-3p in endometriosis during the secretory phase of menstrual cycle: Insights from a case-control study on molecular biomarkers and disea... by Yasaman Nazari Hagh, Mohamadreza Ahmadifard, Sedigheh Esmaelzadeh, Soheila Abbaszadeh, Naser Shokrzadeh

“…It is reported that it affects about 20–25% of all infertile women. Some genetic markers play a crucial role in pathogenesis and infertility. …”
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The O-glycosyltransferase C1GALT1 promotes EWSR1::FLI1 expression and is a therapeutic target for Ewing sarcoma by Shahid Banday, Alok K. Mishra, Romana Rashid, Tianyi Ye, Amjad Ali, Junhui Li, Jason T. Yustein, Michelle A. Kelliher, Lihua Julie Zhu, Sara K. Deibler, Sunil K. Malonia, Michael R. Green

“…Itraconazole, an FDA-approved anti-fungal agent that is known to inhibit C1GALT1, reduces EWSR1::FLI1 levels in ES cell lines and suppresses growth of ES xenografts in mice. …”
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The effect of differences in the third domain of the glycoprotein E of tick-borne encephalitis virus of the Far Eastern, Siberian and European subtypes on the binding of recombinan... by I. K. Baykov, A. L. Matveev, L. A. Emelianova, G. B. Kaverina, S. E. Tkachev, N. V. Tikunova

“…In addition, information about the spatial arrangement of amino acid residues that are different for the studied recombinant proteins indicates that the epitope recognized by the ch14D5 antibody is in close proximity to the lateral ridge of D3 domain of E glycoprotein.…”
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Status of continuous glucose monitoring use and management in tertiary hospitals of China: a cross-sectional study by Xiaoqin Liu, Hongmei Dai, Liping Wu, Yong Zhao, Zumin Shi, Qin Lin, Liping Chen

“…Head nurses perceived patients’ limited knowledge about CGM (60.2%), the high costs of CGM and inaccessibility to medical insurance (59.0%), and imperfect CGM management systems (44.6%) as the top three factors. …”
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Ghanaian women’s experience of intimate partner violence (IPV) during group antenatal care: a brief report from a cluster randomised controlled trial by Samia J. Abdelnabi, Michelle L. Munro-Kramer, Cheryl A. Moyer, John E.O. Williams, Jody R. Lori

“…Added knowledge: Group Antenatal Care has been identified as an effective modality for providing antenatal care and facilitating conversations about sensitive topics such as intimate partner violence and safety. …”
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You cannot be what you cannot see: a retrospective natural longitudinal cohort study exploring the impact of face-to-face rural immersion on student medical training satisfaction a... by Srinivas Kondalsamy-Chennakesavan, Matthew R McGrail, Bushra F Nasir, Alan Bruce Chater

“…Comparatively, students’ satisfaction with the RRM programme remained steady across all the years at about 85–90%.Conclusions There appears to be a detrimental impact of a lack of immersive community-engaged education experiences on medical student’s intention to pursue a rural medical career. …”
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Clinical trials on carotenoids and vitamin mineral supplements in ophthalmology by A.A. Gvetadze, M.G. Rabadanova

“…Russian Journal of Clinical Ophthalmology. 2019;19(1):38–41.<br> <br> <b>About the authors:</b><br> ¹Anna A. Gvetadze — MD, PhD, ophthalmologist;<br> ^1,2Madina G. …”
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Effects of Adoption of Agricultural Technologies on Irish Potato Yield in Ol Kalou Sub-County Kenya: Application of Endogenous Switching Regression Model by David Kihoro, Geofrey Kingori Gathungu, Rael Nkatha Mwirigi, Vicky Nyambura Wairimu

“…However, despite the high potential of about 30 tonnes per hectare (ha), smallholder farmers in Kenya realize low Irish potato yields ranging from 4-8 tonnes per ha due to limited uptake of agricultural technologies. …”
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Trait mindfulness in early pregnancy and adverse perinatal outcomes: a prospective cohort study by Audra C. Fain, Tess E. K. Cersonsky, Margaret H. Bublitz, Adam K. Lewkowitz, Erika F. Werner, Emily S. Miller, Nina K. Ayala

“…There is emerging evidence that mindfulness training (MT) can also be harnessed to improve somatic outcomes. Yet, little is known about which perinatal populations might benefit the most from mindfulness training interventions. …”
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上调microRNA-205表达对HeLa细胞生物学特性的影响

“…【目的】 探讨上调microRNA-205(miR-205)表达对HeLa细胞生物学特性的影响65377;【方法】 实验分4组:miR-205上调组,阴性对照组,空白转染组和空白对照组65377;每种检测重复3次65377;利用脂质体siPORT NeoFX Transfection Agent,向miR-205上调组细胞转染Pre-miR-hsa-miR-205 miRNA Precursor,阴性对照组细胞转染Cy3 dye labeled PremiR Negative Control65377;荧光显微镜下评估转染情况,实时定量PCR方法检测miR-205表达,四甲基偶氮唑蓝(MTT)法和平板克隆形成实验分别检测细胞生长和增殖能力,流式细胞术检测细胞凋亡率和细胞周期分布,Transwell小室法检测细胞迁移能力65377;【结果】 实时定量PCR结果显示,miR-205上调组miR-205的表达增加3061.5倍65377;与空白对照组相比,72 h miR-205上调组与阴性对照组活细胞数分别为(126 ± 41)%,(126 ± 39)%;两组克隆形成率分别为(79 ± 11)%,(63 ± 10)%;凋亡率分别为(4.6 ± 2.1)%,(4.1 ± 2.4)%;S期细胞比例分别为(19.2 ± 3.6)%,(23.4 ± 3.0)%;200倍镜视野下迁移细胞数分别为63 ± 17和68 ± 1665377;与对照组比,miR-205上调组细胞增殖能力增强但生长曲线不受影响,S期细胞比例降低,而凋亡率不变,细胞迁移能力无明显改变65377; 【结论】 上调miR-205表达后,HeLa细胞增殖能力及细胞周期改变,但生长曲线65380;凋亡率和迁移能力无变化65377;…”
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Quality of Life Philosophy IV. The Brain and Consciousness by Søren Ventegodt, Niels Jørgen Andersen, Joav Merrick

“…The great question is why this consciousness about the world, provided by the brain, is not a gift that makes life better instead of getting us expelled from the Garden of Eden. …”
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Astaxanthin Protects Primary Hippocampal Neurons against Noxious Effects of Aβ-Oligomers by Pedro Lobos, Barbara Bruna, Alex Cordova, Pablo Barattini, Jose Luis Galáz, Tatiana Adasme, Cecilia Hidalgo, Pablo Muñoz, Andrea Paula-Lima

“…Here, we investigated whether the antioxidant agent astaxanthin (ATX) protects neurons from AβOs-induced excessive mitochondrial ROS generation, NFATc4 activation, and RyR2 mRNA downregulation. …”
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