Ginger polysaccharide UGP1 suppressed human colon cancer growth via p53, Bax/Bcl-2, caspase-3 pathways and immunomodulation by Yanfang Qian, Chenying Shi, Chen Cheng, Dengwei Liao, Junping Liu, Gui-tang Chen

“…This investigation provided basic theoretical mechanism of ginger polysaccharide-exerted antitumor activities, and contributed to develop a possible functional food or adjuvant agent for prevention or treatment of colon cancer.…”
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FRR: A Fast Routing Recovery mechanism minimizing network formation time in smart grids by Giancarlo C. Heck, Ananias A. Quispe, Patryk H. da Fonseca, Osni S. Junior, Roberto A. Hexsel, Luiz C.P. Albini

“…In this article, we propose a mechanism called Fast Routing Recovery (FRR), which aims to accelerate the reconnection process in networks that use the RPL protocol by memorizing information about the nodes’ preferred parents. We evaluate the FRR mechanism by simulations and experiments. …”
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Is Everyone Beating Around the Bush?: A Qualitative Study Examining the Status of Shared Decision-Making Between Veterans Affairs Providers and Surgical Patients in the ICU by M. Andrew Millis, MD, MPH, C. Ann Vitous, MA, MPH, Cara Ferguson, BS, Maedeh Marzoughi, BS, Erin Kim, BS, Sarah E. Bradley, PhD, MPH, CPH, Ashley Duby, MS, Pasithorn A. Suwanabol, MD, MS

“…Participant dialogue was deductively mapped into 8 established SDM components: describing treatment options; determining roles in the decision-making process; fostering partnerships; health care professional preferences; learning about the patient; patient preferences; supporting the decision-making process; and tailoring the information. …”
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Exploring the general practitioners’ perception of the inter-professional care of rheumatoid arthritis patients (GEPRA—II): a qualitative interview study by Anne-Laure Yailian, Audrey Janoly-Dumenil, Emmanuelle Vignot, Aurélie Fontana, Charline Estublier, Cyrille Confavreux, Roland Chapurlat, Claude Dussart, Humbert de Freminville

“…Conclusions The implementation of a collaborative patient support programme in RA should be developed taking into account the barriers and facilitators identified by GPs who appeared to be aware of the causes of potential non-adherence, and were particularly interested in receiving more information about the therapeutic monitoring of patients by hospital professionals.…”
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Cooperative Overbooking-Based Resource Allocation and Application Placement in UAV-Mounted Edge Computing for Internet of Forestry Things by Xiaoyu Li, Long Suo, Wanguo Jiao, Xiaoming Liu, Yunfei Liu

“…Simulation results verify that the proposed cooperative resource overbooking schemes can save more computing resource in cases including more tenants with higher or differentiated resource demand violation ratio (RDVR) thresholds, and the FFD-ACP scheme can reduce about one third of necessarily deployed UAVs compared with traditional overbooking. …”
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Prevalence of Active Trachoma and Associated Factors in Areka Town, South Ethiopia, 2018 by Melese Menta Alambo, Eyasu Alam Lake, Shimelash Bitew Workie, Addisu Yeshambel Wassie

“…Similarly, children with caretakers having inadequate knowledge about trachoma (AOR = 8.10; 95% CI: 2.04–32.17) were more likely to develop active trachoma. …”
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Life-history traits, pace of life and dispersal among and within five species of Trichogramma wasps: a comparative analysis by Guicharnaud, Chloé, Groussier, Géraldine, Beranger, Erwan, Lamy, Laurent, Vercken, Elodie, Dahirel, Maxime

“…Such axes, along with their potential associations or syndromes with other traits such as dispersal, are however not universal; in particular, support for their presence may be taxon and taxonomic scale-dependent. Knowing about such life-history strategies may be especially important for understanding eco-evolutionary dynamics, as these trait syndromes may constrain trait variation or be correlated with other traits. …”
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A transgenic cell line with inducible transcription for studying (CGG)n repeat expansion mechanisms by I. V. Grishchenko, A. A. Tulupov, Y. M. Rymareva, E. D. Petrovskiy, A. A. Savelov, A. M. Korostyshevskaya, Y. V. Maksimova, A. R. Shorina, E. M. Shitik, D. V. Yudkin

“…These experimental systems can serve for f inding the causes of instability and the development of therapeutic agents. In addition, a criterion was developed for the quantif ication of exogenous (CGG)n repeat instability in the transgenic cell lines’ genome.…”
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Evaluation of the antibacterial activity of essential oils from oregano (Origanum vulgare) against Escherichia coli strains isolated from meat products by L. Brito-Junior, H. C. Brito, M. M. Simões, B. Santos, F. M. C. Marques, M. A. A. Medeiros, M. S. Alves, J. H. A. Farias, C. T. Pereira, A. F. Diniz, A. A. Oliveira-Filho, V. L. R. Vilela

“…Furthermore, the oil was effective in inhibiting the adherence of E. coli bacterial strains, demonstrating a more significant antibiofilm agent than 0.12% chlorhexidine digluconate, a commonly used antibacterial. …”
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Macrophage Activities in Myocardial Infarction and Heart Failure by Sophia Esi Duncan, Shan Gao, Michael Sarhene, Joel Wake Coffie, Deng Linhua, Xingru Bao, Zhang Jing, Sheng Li, Rui Guo, Jing Su, Guanwei Fan

“…Advances in pharmacological and biomedical management have resulted in an increasing proportion of patients surviving acute heart failure (HF). However, many survivors of HF in the early stages end up increasing the disease to chronic HF (CHF). …”
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Near-Infrared Spectroscopy as a Process Analytical Technology Tool for Monitoring the Steaming Process of Gastrodiae rhizoma with Multiparameters and Chemometrics by Yamin Zuo, Jing Yang, Chen Li, Xuehua Deng, Shengsheng Zhang, Qing Wu

“…In this study, the potential usage of NIR spectroscopy to monitor the steaming process of Gastrodiae rhizoma was explored. About 10 lab scale batches were employed to construct quantitative models to determine four chemical ingredients and moisture change during the steaming process. …”
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Different Modulating Effects of Adenosine on Neonatal and Adult Polymorphonuclear Leukocytes by Pei-Chen Hou, Hong-Ren Yu, Ho-Chang Kuo, Lin Wang, Li-Yan Lin, Jiunn-Ming Sheen, Te-Yao Hsu, Chia-Yu Ou, Yi-Jyun Jheng, Kuender D. Yang, Wen-Hsin Cheng

“…Neonatal plasma has a higher adenosine level than that of adults; however, little is known about the modulating effects of adenosine on neonatal PMNs. …”
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Dynamically triggered seismicity in Japan following the 2024 M w 7.5 Noto earthquake by Like An, Bogdan Enescu, Zhigang Peng, Masatoshi Miyazawa, Hector Gonzalez-Huizar, Yoshihiro Ito

“…We also report potential, less well-constrained dynamic triggering by the Mw 5.3 Noto foreshock, which occurred ~ 4 min before the mainshock, at levels of stress about 100 times smaller. The analysis of a longer-term (1 month) seismicity pattern, based on the JMA catalog, revealed a statistically significant increase of seismicity in the remote Akita–Yakeyama (Tohoku region) volcanic area, following the Noto earthquake. …”
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Spatial transcriptomic analysis drives PET imaging of tight junction protein expression in pancreatic cancer theranostics by James Wang, Jai Woong Seo, Aris J. Kare, Martin Schneider, Mallesh Pandrala, Spencer K. Tumbale, Marina N. Raie, Gokce Engudar, Nisi Zhang, Yutong Guo, Xiaoxu Zhong, Sofia Ferreira, Bo Wu, Laura D. Attardi, Guillem Pratx, Andrei Iagaru, Ryan L. Brunsing, Gregory W. Charville, Walter G. Park, Katherine W. Ferrara

“…We develop a peptide-based molecular imaging agent targeted to claudin-4 with accumulation to ~25% injected activity per cubic centimeter (IA/cc) in metastases and ~18% IA/cc in tumors. …”
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The Expression of T Cell FOXP3 and T-Bet Is Upregulated in Severe but Not Euthyroid Hashimoto’s Thyroiditis by Stana Tokić, Mario Štefanić, Ljubica Glavaš-Obrovac, Sonja Jaman, Eva Novosadová, Jana Petrkova, Zdenka Navratilova, Mirjana Suver Stević, Martin Petrek

“…Th1 and Treg subset of CD4+ cells have been implicated in the pathogenesis; however, less is known about their respective roles across the spectrum of HT clinical presentations. …”
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Virulence-associated variants in Cryptococcus neoformans sequence type 93 are less likely to be associated with population structure compared to independent rare mutations by Katrina M. Jackson, Kisakye Diana Kabbale, Marissa Macchietto, David Meya, Peter Tiffin, Kirsten Nielsen

“…ABSTRACT Cryptococcus neoformans is a pathogenic yeast that is the causative agent of cryptococcal meningitis. While it is well known that the genotype of C. neoformans impacts patient outcomes, the reason for this association has not been well elucidated. …”
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Kalar1 and Kalar2, Newly Released Wheat Varieties for Cultivation under Rain-fed Conditions by Star Ali Awtaq, Ali Shamsullah Azeez, Yadgar Ali Mahmood, Narmeen Rashid Abdulkareem, Khalil Musa Jamal

“…Averaging over years, the results of this project significantly confirmed that two of the selected lines (SL1 and SL2) performed superior (4.24 and 4.73 t h-1, respectively) to the local check (Aras; 2.83 t h-1) with regards to grain yield production by about 50-60% (P < 0.001). This superiority of the selected lines compared to the local check was due to significant longer spike through increasing grain number (P < 0.001), and wider flag-leaf area which leads to assimilate more CO2 to the grain during grain filling duration (P < 0.01). …”
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Molecular Mechanisms of Breast Cancer Drug Resistance and CRISPR/Cas9 Strategies to Overcome by Bashdar Mahmud Hussen, Bnar Saleh Ismael, Saman S. Abdulla, Noor Haval Jamal, Suhad Asad Mustafa, Zana Baqi Najmalddin, Mohammed Fatih Rasul

“…The CRISPR/Cas9 technology's selective disruption or mutation of these genes provides valuable information about their role in resistance and paves the path for cutting-edge treatment options. …”
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Green synthesis and enhanced photocatalytic performance of Co-Doped CuO nanoparticles for efficient degradation of synthetic dyes and water splitting by Daniel Masekela, Lovedonia K. Kganyakgo, Kwena D. Modibane, Tunde L. Yusuf, Sheriff A. Balogun, Wilson M. Seleka, Edwin Makhado

“…Under UV–vis light irradiation, Co-doped CuO NPs achieved photocatalytic degradation efficiency of about 88 % within 100 min, whereas for pristine CuO NPs it was 75 % under the same irradiation time. …”
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Strategizing Simultaneous Spinal Osteotomy and Total Hip Replacement in Ankylosing Spondylitis by Chen Guo, Yan Liang, Zhenqi Zhu, Shuai Xu, Haiying Liu

“…Furthermore, the Spine First Group exhibited more pronounced changes in pelvic parameters (p = 0.009), albeit at the expense of longer operation times and increased blood loss. …”
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