Trillin inhibits MAP3K11/NF-κB/COX-2 signaling pathways through upregulation of miR-145-5p in castration-resistant prostate cancer by Yanlong Wang, Yulin Peng, Wenjun Hao, Chengjian He, Xiang Gao, Peng Liang, Haolin Zhao, Ying Wang, Liang Wang, Zhenlong Yu, Zhiyu Liu

“…These findings suggest that Trillin may offer a promising alternative approach for targeting CRPC, highlighting its potential as a therapeutic agent to improve patient outcomes.…”
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Endometrial Carcinoma Presenting with an Isolated Osseous Metastasis: A Case Report by Nesrine Tounsi, Ines Zemni, Fatma Saadalah, Maher Slimane, Nadia Boujelbene, Mohamed ali Ayadi, Chargui Rhiad, Rahal Khaled

“…We present a case of a 56-year-old woman treated for endometrial cancer with isolated ribs bone metastases. She was complaining about progressive right rib pain as a first sign of the disease of endometrial cancer. …”
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Environmental Challenges Faced by a Kindergarten and a School in the Katima Mulilo Education Circuit by Давид Нкенгбеза, Мундія Кілібоні Еустінах, Євген Літаба Маемеко, Муквамбо Музва

“…This method is appropriate for this study because participants were required to share their perspectives and express their thoughts about their school environment, allowing researchers to gather detailed experiences and feedback from the population. …”
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A Retrospective Study Comparing Nose, Lip, and Chin Morphology in Class I, Class II, and Class III Skeletal Relationships in Patients Visiting to the Department of Orthodontics, BP... by Avinash Chaudhary, Jamal Giri, Rajesh Gyawali, Prabhat Ranjan Pokharel

“…With the changing paradigm from primarily hard tissue to soft tissue evaluation for orthodontic diagnosis and treatment planning, the priority has shifted to bring about improvement in the profile and smile characteristics of patients. …”
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Safety Evaluation for Connected and Autonomous Vehicles’ Exclusive Lanes considering Penetrate Ratios and Impact of Trucks Using Surrogate Safety Measures by Jian Zhang, Kunrun Wu, Min Cheng, Min Yang, Yang Cheng, Shen Li

“…Plenty of studies on exclusive lanes for Connected and Autonomous Vehicle (CAV) have been conducted recently about traffic efficiency and safety. However, most of the previous research studies neglected comprehensive consideration of the safety impact on different market penetration rates (MPRs) of CAVs, traffic demands, and proportion of trucks in mixture CAVs with human’s driven vehicle environment. …”
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Beyond destruction: emerging roles of the E3 ubiquitin ligase Hakai by Juan-José Escuder-Rodríguez, Andrea Rodríguez-Alonso, Lía Jove, Macarena Quiroga, Gloria Alfonsín, Angélica Figueroa

“…Most of the knowledge about the protein was associated to its E3 ubiquitin ligase canonical role. …”
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Evaluation of Regulatory Immune Response in Skin Lesions of Patients Affected by Nonulcerated or Atypical Cutaneous Leishmaniasis in Honduras, Central America by Gabriela Venicia Araujo Flores, Carmen Maria Sandoval Pacheco, Thaise Yumie Tomokane, Wilfredo Sosa Ochoa, Concepción Zúniga Valeriano, Claudia Maria Castro Gomes, Carlos Eduardo Pereira Corbett, Marcia Dalastra Laurenti

“…Considering that little is known about the pathogenesis of NUCL, the aim of this study was to evaluate the regulatory response in situ in skin lesions of patients affected by NUCL. …”
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Reduction of injury rate when introducing automated control systems of production processes at energy enterprises by R. N. Pigilova, F. M. Filippova, Yu. A. Averyanova

“…The research showed that an automated process control system is the most effective tool: it provides operational information about the process, the condition of equipment and controls, significantly reduces non-production costs and energy losses. …”
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The hidden cost of digital learning: a cross-sectional study assessing the prevalence of computer vision syndrome (CVS) among medical students in Jordan by Hazim Alkousheh, Yara Alkousheh, Rana Qawaqzeh, Layan Al Juneidi, Lina Al-Zerikat, Ayat Hussain, Motasem Al-latayfeh

“…Symptoms, attack duration and frequency were higher, especially in females, highlighting the need for preventive measures and increased awareness about prolonged screen use.…”
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Geodetic data inversion to estimate a strain-rate field by introducing sparse modeling by Yohei Nozue, Yukitoshi Fukahata

“…As a result, the proposed method estimates about $$1.0\times {10}^{-8}$$ 1.0 × 10 - 8 /yr faster strain rates near the fault zone than the L2 regularization method, which corresponds to a 20–30% greater strain-rate concentration. …”
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Improving patient safety through better teamwork: how effective are different methods of simulation debriefing? Protocol for a pragmatic, prospective and randomised study by Wolf E Hautz, Juliane E Kämmer, Julia Freytag, Fabian Stroben, Dorothea Eisenmann

“…All students will participate voluntarily and will sign an informed consent after receiving written and oral information about the study. Results will be published.…”
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Variations in carbon stocks across traditional and improved agroforestry in reference to agroforestry and households’ characteristics in Southeastern Ethiopia by Boja Tilinti, Mesele Negash, Zebene Asfaw, Teshale Woldeamanuel

“…The results indicated that biomass carbon in improved HGAF practice was about 11.8 % higher than in traditional ones. Old age HGAF had 8.7 % and 49.4 % significantly higher biomass carbon than medium and young age HGAF, respectively. …”
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The Power of Perception: Unpacking the Role of Negative Thinking in High School Students’ Test Anxiety by Damla Kahraman, Elif Özüm Kuş Işık, Mehmet Hakan Türkçapar, Cemile Dur Öztürk, Duygu Betül Özkanca, Nilüfer Koçtürk, Eyüp Sabır Erbiçer, Türkan Doğan, Ercan Akın

“…Other-oriented domain contained two themes: blaming others and concern about the social consequences of failing. The future-orientated domain had two themes: reading the future and intolerance to uncertainty. …”
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Consumer attitudes and behavior towards organic products: Evidence from the Lithuanian market by Lina Pilelienė, Vilma Tamulienė

“…The research results show the high level of Lithuanian consumers’ environmental consciousness; also, a willingness to share information relating to environmental issues with friends; and active engagement in sharing information about environmentally related issues. However, consumer awareness of the relationship between organic products, and health and quality issues is lower, indicating the necessity to be managed. …”
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Smallpox vaccination in a mouse model by S. N. Shchelkunov, A. A. Sergeev, S. A. Pyankov, K. A. Titova, S. N. Yakubitskiy

“…The monkeypox epidemic, which became unusually widespread among humans in 2022, has brought awareness about the necessity of smallpox vaccination of patients in the risk groups. …”
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Picosecond Laser Etching of Glass Spiral Microfluidic Channel for Microparticles Dispersion and Sorting by Rong Chen, Shanshan He, Xiansong He, Jin Xie, Xicong Zhu

“…The channel surface roughness reached about 500 nm or less when the laser power was 9 W, the scanning speed was 1000 mm/s, and the cumulative number was 4. …”
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“I definitely cannot afford to be feeling poorly if there’s no need to be”: a qualitative evaluation of antiviral uptake following suspected occupational exposure to avian influenz... by Riinu Pae, Lucy Findlater, Richard Amlôt, Fernando Capelastegui, Gavin Dabrera, Clare Humphreys, Jharna Kumbang, Isabel Oliver

“…Public health interventions should prioritise those at most risk and address multiple components of behaviour, such as advising how to manage side effects, addressing concerns about long-term usage and providing convenient access to antivirals for those at most risk.…”
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Early measures for prevention and containment of COVID-19 in the Maldives: A descriptive analysis by Mariyam SUZANA, Sheena MOOSA, Fathmath Nazla RAFEEG, Sofoora K. USMAN

“…Maldives delayed the entry of the pandemic into the country by about 90 days, and maintained its testing rate at fourth highest among United Nations Small Island Developing States and highest among the South East Asian countries. …”
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Effect of Covid-19 on maternal and child health services utilization in Ghana. Evidence from the National Health Insurance Scheme (NHIS). by Yaw Nyarko Opoku-Boateng, Emmanuel Opoku-Asante, Mylene Lagarde, Edward Nketiah-Amponsah

“…Maternal and newborn care were adversely affected but little or nothing is known about the impact it has caused to it. This study seeks to determine the effect of Covid-19 on healthcare utilization with specifics on Antenatal, Postnatal, Deliveries and Out-patient attendance.…”
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Pantoprazole Decreases Cell Viability and Function of Human Osteoclasts In Vitro by Markus Prause, Claudine Seeliger, Marina Unger, Elizabeth Rosado Balmayor, Martijn van Griensven, Alexander Tobias Haug

“…Proton pump inhibitors (PPIs) are commonly prescribed drugs that decrease stomach acidity and are thus often used to treat gastroesophageal reflux disease and as a preventative agent for the adverse effects of nonsteroidal anti-inflammatory drugs on the stomach mucosa. …”
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