Fabrication of glipizide loaded polymeric microparticles; in-vitro and in-vivo evaluation. by Qaiser Rasheed, Kamran Ahmad Khan, Ghulam Razaque, Ashfaq Ahmad, Asif Nawaz, Naheed Akhtar, Kifayat Ullah Shah, Zahid Rasul Niazi, Muhammad Danish Saeed, Anila Alam

“…In this study, we aimed to design controlled-release microparticles of Glipizide utilizing Eudragit S100 and Methocel K 100 M polymers as controlling agents. The microparticles were fabricated through a simple solvent evaporation method, employing various drug-to-polymer ratios to formulate different controlled-release batches labeled as F1 to F5. …”
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Identifying RBBP7 as a Promising Diagnostic Biomarker for BK Virus-Associated Nephropathy by Yicun Wang, Yuxuan Wang, Di Zhang, Hao Zhang, Wei Wang, Xiaopeng Hu

“…Besides, potential drugs for BKVN treatment such as mepacrine were discovered, which may contribute to targeted antiviral therapy and effective patient management rather than simply reducing the doses of immunosuppressive agents in clinical practice. RBBP7 (retinoblastoma binding protein 7) serves as component of serval complexes that regulate chromatin metabolism and functions in affecting DNA replication and controlling cell proliferation. …”
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Chitosan and its derivatives as promising plant protection tools by A. B. Shcherban

“…Recently, biological PPPs based on natural compounds have attracted more attention, since they do not have these disadvantages, but at the same time they can be no less effective. One of such agents is chitosan, a deacetylation product of chitin, one of the most common polysaccharides in nature. …”
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Relación entre depresión y adherencia al tratamiento en diabetes tipo 2, considerando la red de apoyo social, las estrategias de afrontamiento y el sexo by José Eduardo Rondón Bernard, Luisa Angelucci

“…Al evaluar los modelos de ecuaciones estructurales, se obtuvieron las mismas medidas de bondad de ajuste, con relaciones similares entre variables, por lo que ambos modelos poseen un ajuste aceptable. Ser mujer, poseer menor estrategia de evitación, presentar mayor red de apoyo, tener menor adherencia al tratamiento, conlleva a una menor depresión. …”
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Empowering nursing students: understanding and addressing bullying experiences in clinical training by Maryam Janatolmakan, Saeedeh Piri, Mohammad Amin Nouri, Alireza Khatony

“…The main themes included “contexts and agents of bullying,” “type of bullying,” “roots and causes of bullying,” “characteristics of the bully,” and “characteristics of the victims.” …”
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Study of SCA-Induced Rock Crack Propagation under Different Stress Conditions Using a Modified Cohesive Element Method by Shen Wang, Hani Mitri, Huamin Li, Dongyin Li, Wen Wang

“…When inducing cracks, soundless cracking agents (SCAs) do not generate vibration, harmful gas, dust, nor flying rock fragment, making them suitable for hard rock roof breaking, rock burst prevention, oil or gas reservoir stimulation, and building demolition. …”
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Emprendimiento memorial by André Caiado Caiado

“…Al examinar cómo el conflicto y los soldados que sirvieron en él son retratados en los espacios museísticos de Portugal, se reflexiona sobre el modo en que las asociaciones de veteranos y los agentes de la memoria utilizan este dispositivo para establecer determinadas representaciones y mensajes sobre este pasado histórico y construir comunidades basadas en mnemónicos. sobre identidades grupales y culturas conmemorativas homogéneas. …”
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Ultrasound-Assisted Extractions for Improving the Recovery of Phenolics and Charantin from Bitter Melon and for Increasing the Antioxidant, Antidiabetic and Anti-Obesity Activities... by Jin Ju Lee, Kyung Young Yoon

“…These results suggest that bioactive compound-rich extracts from bitter melon obtained using UAE, especially UAE-P-E, are expected to have high application potential as a functional food material, and are also expected to be used as natural antioxidant, antidiabetic, and anti-obesity agents.…”
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Exploration Degree Bias: The Hidden Influence of Node Degree in Graph Neural Network-Based Reinforcement Learning by Peter Tarabek, David Matis

“…Moreover, analysis of DQN and PPO RL agents illustrates how EDB can distort exploration patterns, with DQN exhibiting EDB under low exploration rates and PPO showing a partial ability to counteract these effects through its probabilistic sampling mechanism. …”
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Molecular Encapsulation of Herbicide Terbuthylazine in Native and Modified β-Cyclodextrin by E. Manuela Garrido, Daniela Rodrigues, Nuno Milhazes, Fernanda Borges, Jorge Garrido

“…Cyclodextrins and modified cyclodextrins were considered, among other substances, appropriate agents for improving pesticide water solubility. Therefore, the inclusion complex formation of terbuthylazine with β-cyclodextrin (β-CD) and hydroxypropyl-β-cyclodextrin (HP-β-CD) was studied to attain its aqueous solubility enhancement. …”
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Enhancing adsorption efficiency for camouflage clothing through activated carbon and inorganic composite coatings by Kittiphop Promdee, Doungkamon Phihusut, Apisake Monthienvichienchai, Natthapong Monarumit

“…This research aimed to study the feasibility of using activated carbon and other powder materials (TiO2, Talc and Bentonite) as a coating for military camouflage clothing, which can provide economic and accessible protection against chemical warfare agents and some types of radiation. The camouflage material was coated through a powder and thermal coating process and analyzed. …”
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Justicias de proximidad en la construcción del orden público en la ciudad de Buenos Aires (1833) by Sofia Gastellu

“…Utilizó el acta electoral del juzgado de paz de Catedral al Norte, confeccionada ya finalizada la Revolución, como observatorio de los cambios de posicionamientos de los actores políticos y los nuevos perfiles de los agentes ligados al gobernador triunfante, Juan Manuel de Rosas. …”
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Antihuman Immunodeficiency Virus Type 1 (HIV-1) Activity of Rare Earth Metal Complexes of 4-Hydroxycoumarins in Cell Culture

“…<p>The cerium Ce(III), lanthanum La(III), and neodymium Nd(III) complexes with 4-hydroxy-3-(3-oxo-1-phenylbutyl)-2H-1-benzopyran-2-one (warfarin) (<bold>W</bold>) and 3,<mml:math alttext="$3'$"> <mml:msup> <mml:mn>3</mml:mn> <mml:mo>&#x2032;</mml:mo> </mml:msup> </mml:math>-benzylidenebis[4-hydroxycoumarin] (<bold>1</bold>) were synthesized and studied for the first time for cytotoxicity (on MT-2 cells) and as anti-HIV agents under acute and chronic infection. The complexes were characterized by different physicochemical methods: mass spectrometry, ¹H NMR, ¹³C NMR, and IR spectroscopy. …”
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OPORTUNIDADES Y CONFLICTOS PARA EL DESARROLLO DEL TURISMO EN EL SUR DEL NEUQUÉN by Miriam N. Cardone

“…Este hecho orientó a los agentes económicos vinculados al turismo a procurar un público que se aventurase en su «descubrimiento» y, por lo tanto, motivó el desarrollo de esta actividad.…”
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Human microbiome, applied to clinical practice by V. T. Ivashkin, K. V. Ivashkin

“…The theory and practice of microbiome causes high potential for justification of the pattern of healthy nutritional pattern, behavior and development of new therapeutic agents.…”
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El espacio público en disputa. El caso de la calle de acceso al campus de la Universidad Nacional del Comahue by Romina Valeria Schroeder

“…La materialización de las acciones pone de manifiesto, en muchos casos, la distancia social, económica entre los diversos actores y agentes que van ejerciendo una apropiación del espacio, cuyo resultado se reflejará, finalmente, en la configuración de la trama urbana. …”
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Estrategias para el fortalecimiento del capital social. Municipio Santos Marquina del Estado Mérida by Juan Carlos Delgado, Eva Lina Lobo, Ligia García

“…Este ar tículo forma par te de una investigación más amplia realizada en el Municipio Santos Marquina del Estado Mérida, en cuatro comunidades: Mucunután, La Mucuy Baja, La Mucuy Alta y Tabay, representativas de las principales actividades económicas que se realizan en la zona, a saber: agricultura, turismo, ar tesanía, comercio y ser vicios, sobre la formación de capital social en el área y su incidencia en el desarrollo económico local, en la cual se abordaron las relaciones de mediación, conflicto y cooperación que se generan entre los diversos agentes y actores públicos, asociativos y privados, así como la capacidad de organización, par ticipación e influencia de éstos en el proceso de formulación, implementación y evaluación de políticas de desarrollo económico local. …”
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Análise de prescrições de antifúngicos em uma Unidade Básica de Saúde do Distrito Federal by Débora Santos Lula Barros, Pedro Juan Ribeiro Calisto dos Santos, Thayanne Nara da Rocha

“…Justificativa e Objetivos: o uso inadequado de agentes antifúngicos acarreta o desenvolvimento de resistência e a falta de efetividade do tratamento, o que pode levar ao agravamento do quadro clínico e à persistência das infecções, ao aumento das taxas e à prolongação das internações hospitalares, além de óbitos e elevação dos custos em saúde. …”
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Actitud del académico hacia la promoción de la Ley de Servicio Comunitario del Estudiante Universitario by Filiberto Martins, María A Cabeza, Agatina Cammaroto, Luz Neris

“…Las condiciones reales del académico presentan aspectos mejorables en sus ámbitos profesional y pedagógico, laboral y cultural para su cónsone desenvolvimiento en su desempeño y en su rol como agente socializador, actitud reflexiva que incide en la responsabilidad y ética que se le atribuye al contexto legal de la Ley de Servicio Comunitario. …”
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Recent advances in electrochemical recovery of rare earth elements from NdFeB magnets by Fu L., Karimi-Maleh H.

“…Thermal demagnetization and mechanical crushing make the magnets brittle and improve the penetration of leaching agents. Acid leaching dissolves the REEs, but also dissolves the iron. …”
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