Caracterización de la oferta de recursos forestales del partido de Balcarce, provincia de Buenos Aires by M. MÓNACO, P. LACLAU

“…Se destaca la utilidad del análisis visual de imágenes del software Google Earth® para la clasificación forestal con técnicas simples y con un grado de precisión aceptable para estudios regionales, y las fuentes de error de esta técnica. …”
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Overview of preclinical and phase II clinical studies on Pegmolesatide’s long-term erythropoiesis stimulating effect via EPOR-mediated signal transduction by Xiaoying Ma, Zhen Li, Lu Zhang, Hui Qian, Qinkai Chen, Ye Tao, Yunfan Li, Dandan Wang, Zhizhen Hu, Weili Luo, Ping Li, Hai Yu, Changlin Mei, Xueqing Yu, Yuanfeng Zhou

“…Results In vitro Pegmolesatide demonstrated enhanced binding stability and prolonged residency at EPOR, surpassing erythropoiesis-stimulating agents (ESAs) rHuEPO and Darbepoetin. This sustained EPOR binding facilitated heightened endogenous EPOR expression post-drug withdrawal, maintaining downstream signal transduction pathways (JAK2/STAT5, ERK1/2 MAPK) for erythropoiesis. …”
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Bone marrow mesenchymal stem cell-derived extracellular vesicles alleviate diabetes-exacerbated atherosclerosis via AMPK/mTOR pathway-mediated autophagy-related macrophage polariza... by Libo Liu, Ziyu An, Huan Zhang, Xueqi Wan, Xin Zhao, Xueyao Yang, Jinfan Tian, Xiantao Song

“…BMSC-EVs thus hold promise as therapeutic agents for atherosclerosis. Graphical Abstract Extracellular vesicles derived from bone marrow mesenchymal stem cells may mitigate diabetes-aggravated atherosclerosis by regulating AMPK/mTOR-mediated autophagy-related macrophage polarization and inhibiting macrophage proliferation, migration, foam cell formation, and cholesterol transport.…”
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Clinical Characteristics and Optimization of Empirical Antimicrobial Therapy for Febrile Neutropenia in Patients With Hematologic Malignancies by Cui Y, Liu X, Feng S

“…In cases of pneumonia, septic shock, or suspected carbapenem-resistant infections, combination therapies with antipseudomonal β-lactams, aminoglycosides, or novel agents like CAZ/AVI are recommended. In patients with FUO, discontinuing broad-spectrum antibiotics may be considered 48 hours after defervescence in clinically stable patients, though premature cessation should be avoided for those with persistent fever. …”
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Diez años del “Programa de evaluación de desempeño de laboratorios de inmunogenética” y su impacto en la “Red de donación y trasplantes” by yazmin rocio arias-murillo, María Angélica Salinas-Nova, Yesith Guillermo Toloza-Pérez, Miguel Ángel Castro-Jiménez

“…Con base en las comparaciones entre laboratorios, se calificó el desempeño de cada uno como «bueno», «aceptable» o «inaceptable» para cada prueba. Se calcularon proporciones y se hizo un análisis de valores predichos con intervalos de confianza del 95 %. …”
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Dysplasie faciale chez les chimpanzés sauvages de Sebitoli, Parc national de Kibale, Ouganda : la pollution environnementale en cause ? by Sabrina Krief, Jean-Michel Krief, Andrew Seguya

“…Ce syndrome résulte d’une perturbation de la formation des structures nasales pendant l’embryogénèse. Des agents anti-vitamine K, ingérés par la mère, sont invoqués dans certains cas. …”
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HPLC and GC-MS analyses of phytochemicals from Ficus carica leaf extract and essential oil along with their antimicrobial properties by Maximilian Lackner, Abdelfattah Z.M. Salem, Mohamed Z.M. Salem, Abeer A. Mohamed, José Luis Ponce-Covarrubias, Shady Selim

“…This work highlights the potential of side stream valorization from fig production to obtain safe and sustainable antimicrobial agents for crop protection, amongst them potatoes, tomatoes, and cucumber.…”
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Phase I study of efineptakin alfa (NT-I7) for the treatment of Kaposi sarcoma by Leonard D’Amico, Martin Cheever, Steven P Fling, Anna Wright, Kathryn Lurain, Ramya Ramaswami, Irene Ekwede, Thomas S Uldrick, Robert Yarchoan, Judith C Kaiser, Angela Shaulov Kask, Manoj P Menon, Paul Couey, Eli Burnham, Allysson Angeldekao, Byung Ha Lee, Li-Lian Kwok, Chia-Ching Jackie Wang

“…Standard chemotherapy agents for KS can contribute to increasing CD4+ T cell lymphocytopenia. …”
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Marine sponge symbiotic bacterial bioremediation against heavy metal pollutants in tiger prawns; Penaeus monodon culture medium by I. Marzuki, I. Pratama, R. Asaf, A. Athirah, K. Nisaa, N. Nurbaya, M. Muslimin, N. Nurhidayah, S. Suwardi, A. Sahrijanna, K. Kamaruddin

“…These symptoms included necrosis, myopathy, and infiltration, which are indicative of decreased cell function due to the presence of toxic agents.CONCLUSION: Bioremediation with Bacillus pumilus and Pseudomonas stutzeri bacteria helped reduce the accumulation of heavy metal pollutants. …”
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13º Jornada do Serviço de Educação Física e Terapia Ocupacional by Hospital de Clínicas de Porto Alegre

“… A Jornada do Serviço de Educação Física e Terapia Ocupacional (SEFTO) do Hospital de Clínicas de Porto Alegre é um evento tradicional, que geralmente ocorre a cada 4 anos, que em razão da pandemia somente pode ser retomada em 2024. …”
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An integrative analysis of ASCL1 in breast cancer and inhibition of ASCL1 increases paclitaxel sensitivity by activating ferroptosis via the CREB1/GPX4 axis by Xiaolu Yang, Xiaolu Yang, Yilun Li, Yilun Li, Yaqi Peng, Yuan Chang, Binglu He, Binglu He, Tianqi Zhang, Tianqi Zhang, Shiyu Zhang, Cuizhi Geng, Yunjiang Liu, Xiaolong Li, Jun Hao, Li Ma

“…The GDSC database was used to examine correlations between ASCL1 levels and sensitivity to standard chemotherapeutic agents. Associations between ASCL1 expression and cytokines, immunomodulatory factors, MHC molecules, and receptors were analyzed using Pearson and Spearman correlation methods. …”
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«Green-Ligand» in Metallodrugs Design—Cu(II) Complex with Phytic Acid: Synthetic Approach, EPR-Spectroscopy, and Antimycobacterial Activity by Kseniya A. Koshenskova, Natalia V. Makarenko, Fedor M. Dolgushin, Dmitriy S. Yambulatov, Olga B. Bekker, Matvey V. Fedin, Sergei A. Dementev, Olesya A. Krumkacheva, Igor L. Eremenko, Irina A. Lutsenko

“…The phytate <b>1</b> is completely deprotonated; six phosphate⁻ fragments (with atoms P1–P6) are characterized by different spatial arrangements relative to the cyclohexane ring (1a5e conformation), which determines two different types of coordination to the complexing agents—P1 and P3, P4, and P6 have monodentate, while P2 and P5 are bidentately bound to Cu²⁺ cations. …”
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Systematic bias between blinded independent central review and local assessment: literature review and analyses of 76 phase III randomised controlled trials in 45 688 patients with... by Jianrong Zhang, Yu Huang, Hengrui Liang, Wenhua Liang, Jianxing He, Yiyin Zhang, Jiaxi He, Jieyu Wu, Long Jiang, Shiyan Tang, Qihua He, Lindsey Tristine Hamblin, Zhiheng Xu, Yaoqi Chen, Difei Chen, Xinyu Wang, Kexin Deng, Shuhan Jiang, Jiaqing Zhou, Jiaxuan Xu, Xuanzuo Chen

“…The aim of this study is to investigate whether systematic bias existed in RCTs by comparing the treatment effects of efficacy endpoints between central and local assessments.Design Literature review, pooling analysis and correlation analysis.Data sources PubMed, from 1 January 2010 to 30 June 2017.Eligibility criteria for selecting studies Eligible articles are phase III RCTs comparing anticancer agents for advanced solid tumours. Additionally, the articles should report objective response rate (ORR), disease control rate (DCR), progression-free survival (PFS) or time to progression (TTP); the treatment effect of these endpoints, OR or HR, should be based on central and local assessments.Results Of 76 included trials involving 45 688 patients, 17 (22%) trials reported their endpoints with statistically inconsistent inferences (p value lower/higher than the probability of type I error) between central and local assessments; among them, 9 (53%) trials had statistically significant inference based on central assessment. …”
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Confocal Microscopy for Detection of Intracellular Bacteria in Urine Samples of patients Suspected with Urinary Tract Infection: A Cross-sectional Observational Study by Bhagyashri Patil-Takbhate, Nilam Memane, Srikanth Tripathy, Nageswari Gandham, Shahzad Mirza

“…Introduction: Uropathogenic bacteria like Escherichia coli (UPEC) and Pseudomonas are the most common agents of Urinary Tract Infection (UTI). Recently, the ability of UPEC to invade urothelial cells and to form Intracellular Bacterial Communities (IBCs) has been described which can be missed out during routine diagnosis and can lead to recurrent infection despite antibiotic treatment. …”
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Dysplasie faciale chez les chimpanzés sauvages de Sebitoli, parc national de Kibale, Ouganda : approches éthologiques, ethnographiques et agronomiques by Régine Gross, Francis Gumisiriza, Bernard T Kiremire, Andrew Seguya, Sabrina Krief

“…Les observations conduites sur les chimpanzés ont permis de mettre en évidence un gêne respiratoire associée à la dysplasie faciale observée : les individus à dysplasie faciale ouvrent plus souvent la bouche que les individus normaux lors des activités de repos, de déplacement et d'alimentation, et leur rythme d’ingestion d’aliments sauvages (Ficus dawei) est également plus lent. …”
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Comment prendre en compte les mobilités saisonnières du bétail dans l’estimation de la charge animale d’un territoire sud-sahélien ? by Yanoussa Yakoubou Alzouma, Pierre Hiernaux, Mahamane Larwanou, Maguette Kaire, Issa Garba, Amadou Adamou Kalilou, Sambo Bode, Mahaman Maaouia Abdou Moussa, Harouna Abdou Bawa

“…Résultats : le cheptel du territoire était composé de 22 028 bovins, 19 597 caprins et 22 374 ovins auxquels s’ajoutent ceux des pasteurs étrangers. Les mesures de poids vifs saisonniers ont permis d’exprimer cette charge en unité de bétail tropical, à savoir 0,38, 0,28 et 0,23UBT/ha en saison des pluies, en saison sèche et fraîche et en saison chaude respectivement. …”
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Redefining outcomes of ventricular arrhythmia for SGLT2 inhibitor medication in heart failure patients: a meta-analysis of randomized controlled trials by Miao Lin, Shiyu Zhang, Lu Zhang, Chengying Yang, Yang Luo, Yajin Peng, Xiaoqiu Tan, Qiang Wen, Xinrong Fan, Xianhong Ou

“…Nevertheless, the impact of these agents on ventricular arrhythmias (VAs) has not been thoroughly investigated. …”
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Biosynthesis and activity of Zn-MnO nanocomposite in vitro with molecular docking studies against multidrug resistance bacteria and inflammatory activators by Samy Selim, Tarek M. Abdelghany, Mohammed S. Almuhayawi, Mohammed K. Nagshabandi, Muyassar K. Tarabulsi, Mohammed Yagoub Mohammed Elamir, Asmaa A. Alharbi, Soad K. Al Jaouni

“…Based on these outcomes, it was concluded that Zn-MnO nanocomposites could be useful agents for the management of multidrug resistant bacterial pathogens and inflammation.…”
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Balanced displacement methods and effect evaluation of heterogeneous combination flooding in different reservoirs by Dejun WU, Jian HOU, Lijie LIU, Kang ZHOU, Zhibin AN

“…However, because of the complex heterogeneity of the actual formation, differences in the deployment of interlayer well networks, and different injection volumes of chemical agents in different layers, the extraction of planar and vertical remaining oil by heterogeneous combination flooding is affected. …”
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Microbial community variations in adult Hyalomma dromedarii ticks from single locations in Saudi Arabia and Tunisia by Myriam Kratou, Apolline Maitre, Apolline Maitre, Apolline Maitre, Lianet Abuin-Denis, Lianet Abuin-Denis, Rachid Selmi, Hanène Belkahia, Abdullah D. Alanazi, Hattan Gattan, Hattan Gattan, Bassam M. Al-Ahmadi, Abdullah F. Shater, Lourdes Mateos-Hernández, Dasiel Obregón, Lilia Messadi, Alejandro Cabezas-Cruz, Mourad Ben Said, Mourad Ben Said

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