Prevalence of Hyper virulence and Multidrug resistance Klebsiella pneumoniae isolates from UTI patients by Manar Abdul karim, Zainab Mohammed Alzubaidy, Khazal Dabua Wadi

“…Ceftazidime and cefepime were used as antimicrobial agents, and the measurements were conducted on Muller-Hinton agar. …”
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Characterization of the Beekeeping Value Chain: Challenges, Perceptions, Limitations, and Opportunities for Beekeepers in Kayonza District, Rwanda by Borden Mushonga, Landouard Hategekimana, Gervais Habarugira, Erick Kandiwa, Alaster Samkange, Basiamisi Victor Ernest Segwagwe

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The influencing factors of the erythropoietin resistance index and its association with all-cause mortality in maintenance hemodialysis patients by Xinju Zhao, Liangying Gan, Fan Fan Hou, Xinling Liang, Xiaonong Chen, Yuqing Chen, Zhaohui Ni, Li Zuo

“…Anemia is a common complication of chronic kidney disease with major option treatment of erythropoiesis-stimulating agents (ESAs). This study aimed to investigate the influencing factors of erythropoietin resistance index (ERI) and its association with mortality in maintenance hemodialysis (MHD) patients. …”
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Promotion of Lotus tenuis and calf early weaning as a good management practice for breeding herds in marginal soils of the Flooding Pampa (Argentina) by M. BAILLERES, M.P. CAMPESTRE, C.J. ANTONELLI, G. MELANI, A. MENÉNDEZ, O.A. RUIZ

“…Asimismo, proporcionó una dieta con un valor nutricional aceptable para la alimentación adecuada de una cantidad considerable de terneros en una superficie pequeña, permitiendo al mismo tiempo, una mejor recuperación de las madres en términos de condición corporal. …”
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Espectro hospedador, prevalencias y dispersión del entonompatógeno Paranosema locustae (Microsporidia) en tucuras (Orthoptera: Acridoidea) del sudoeste de Buenos Aires by Carlos E. Lange, Maria L. de Wysiecki

“…En el laboratorio, se examinaron en forma individual por homogenización o disección para detectar la presencia de Paranosema locustae, un agente para el control biológico de tucuras a largo plazo. …”
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Loan Monitoring Costs and Loan Payment in SACCOs: A Case Study of Mitooma People's SACCO in Mitooma Town Council Mitooma District. by Mugarura, Adison

“…The study findings also revealed that loan clearance and dealing with the defaulters affects the recipients negatively, loan monitoring also determines whether the remaining contingency reserves for cost and schedules are adequate, loans with high loan monitoring have higher monthly payments or take longer to pay off than loans with low loan monitoring, therefore the higher loan monitoring charged by most financial institutions as a loaning requirement hinders loan request which affects the socio-economic status of the recipients and women are given little or no loans because they lack collaterals as a requirement from the financial institution and this retards development, the interest rate mostly does not favor women who are considered to be the agents for development. Women's access to formal sources of loans is restricted because they often lack collateral as a requirement needed by the microfinance and the inability to retrieve all loans due to the relocation of business activity or the residence of defaulters also affects loan monitoring in SACCOs affects of loan monitoring on loan repayment and recovery in SACCOs. …”
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Galectin-3 secreted by triple-negative breast cancer cells regulates T cell function by Annat Raiter, Yael Barhum, Julia Lipovetsky, Chen Menachem, Sharona Elgavish, Shmuel Ruppo, Yehudit Birger, Shai Izraeli, Orna Steinberg-Shemer, Rinat Yerushalmi

“…However, the substantial variation in immune response prompts an urgent need for new immune-targeting agents. This requires a comprehensive understanding of TNBC's tumor microenvironment. …”
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FNDC5/irisin mitigates the cardiotoxic impacts of cancer chemotherapeutics by modulating ROS-dependent and -independent mechanisms by Manish Kumar, Abhishek Singh Sengar, Anushree Lye, Pranesh Kumar, Sukhes Mukherjee, Dinesh Kumar, Priyadip Das, Suvro Chatterjee, Adele Stewart, Biswanath Maity

“…In fact, FNDC5 forms a co-precipitable complex with Chk1 alluding to possible intracellular actions for this canonically membrane-associated protein. …”
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Targeting enolase 1 reverses bortezomib resistance in multiple myeloma through YWHAZ/Parkin axis by Xuejie Gao, Qilin Feng, Qikai Zhang, Yifei Zhang, Chaolu Hu, Li Zhang, Hui Zhang, Guanli Wang, Ke Hu, Mengmeng Ma, Zhuning Wang, Yujie Liu, Dong An, Hongfei Yi, Yu Peng, Xiaosong Wu, Gege Chen, Xinyan Jia, Haiyan Cai, Jumei Shi

“…Furthermore, combination treatment with bortezomib and pharmaceutical agents targeting ENO1 has synergistic anti-MM effects both in vivo and in vitro. …”
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Influence of Dentin Priming with Tannin-Rich Plant Extracts on the Longevity of Bonded Composite Restorations by Mackeler Ramos Polassi, Thales de Sá Oliveira, Ana Calheiros de Carvalho, Lívia Soman de Medeiros Medeiros, Thiago André Moura Veiga, Carlos Frederico de Oliveira Graeff, Alejandra Hortencia Miranda González, Maria Cristina Marcucci, Simone dos Santos Grecco, Paulo Henrique Perlatti D’Alpino

“…This in vitro study evaluated the influence of bioactive plant extracts as dentin biomodifying agents to improve the longevity of bonded restorations. …”
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Traumatic dental injuries in the first year of life and related risk factors in three regions of Brazil: a multicenter birth cohort study by Carlos Alberto Feldens, Bruno Antonio Sehn Konzen, Elisa Maria Rosa de Barros Coelho, Alessandra Castro Alves, Eliane Gerson Feldens, Márcia Regina Vítolo, Paulo Floriani Kramer

“…Methods A birth cohort study was conducted with children in the cities of Porto Alegre, Salvador, and Manaus. Socioeconomic, demographic, and anthropometric characteristics were collected at baseline. …”
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PDL1 inhibitors may be associated with a lower risk of allograft rejection than PD1 and CTLA4 inhibitors: analysis of the WHO pharmacovigilance database by Alexandre O. Gérard, Alexandre O. Gérard, Alexandre O. Gérard, Diane Merino, Diane Merino, Jonathan Benzaquen, Alexandre Destere, Delphine Borchiellini, Clément Gosset, Clément Gosset, Fanny Rocher, Marine Andreani, Charles-Hugo Marquette, Henri Montaudié, Henri Montaudié, Milou-Daniel Drici, Antoine Sicard, Antoine Sicard

“…Immune checkpoint inhibitors (ICI) have improved survival rates, but data on the use of these agents in transplant recipients is scarce. ICI may trigger allograft rejection, but the absolute risk of AR between the different ICI classes remains to be defined.MethodsVigiBase® (WHO’s pharmacovigilance database) was queried for reports of AR involving CTLA4, PD1, or PDL1 inhibitors. …”
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Effects of Glucagon-Like Peptide-1 Receptor Agonists on Weight Loss in Patients with Type 2 Diabetes: A Systematic Review and Network Meta-Analysis by Feng Sun, Sanbao Chai, Lishi Li, Kai Yu, Zhirong Yang, Shanshan Wu, Yuan Zhang, Linong Ji, Siyan Zhan

“…Network meta-analysis found that EX10BID, LIR1.8QD, and EX2QW obtained a higher proportion of patients with weight loss than other traditional hypoglycemic agents. Our results suggest GLP-1 RAs are promising candidates for weight control in comparison with traditional hypoglycemic drugs, and EX10BID, LIR1.8QD, and EX2QW rank the top three drugs.…”
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Flavonoids and anthocyanins in seagrasses: implications for climate change adaptation and resilience by Jana Botes, Jana Botes, Xiao Ma, Xiao Ma, Jiyang Chang, Jiyang Chang, Yves Van de Peer, Yves Van de Peer, Yves Van de Peer, Yves Van de Peer, Dave Kenneth Berger, Dave Kenneth Berger

“…Flavonoids will likely prove to be effective and versatile agents in combating the new host of stress conditions introduced to marine environments by anthropogenic climate change, which affects marine environments differently from terrestrial ones. …”
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Canadian Rhinology Working Group consensus statement: biologic therapies for chronic rhinosinusitis by Andrew Thamboo, S. Kilty, I. Witterick, Y. Chan, C. J. Chin, A. Janjua, A. Javer, J. Lee, E. Monterio, B. Rotenberg, J. Scott, K. Smith, D. D. Sommer, L. Sowerby, M. Tewfik, E. Wright, M. Desrosiers

“…Therefore, biologics, monoclonal antibody agents, could be beneficial therapeutic treatments for these patients. …”
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A caminho da festa: um estudo de caso de procedimentos metodológicos aplicados em uma pesquisa sobre lazer by Ilse Lorena Von Borstel Galvão de Queirós

“… Objetivo: Este estudo teve como objetivo compreender os interesses, valores e significados da participação dos descendentes de alemães na 11ª Oktoberfest, realizada em Marechal Cândido Rondon, Paraná, abordando-a como uma atividade de política pública e espaço de vivência do lazer. …”
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Donafenib combined with sintilimab for advanced hepatocellular carcinoma: a single arm phase II trial by Xiaoyang Hong, Yongjian Guo, Wenbo Shi, Kangshun Zhu, Licong Liang, Liteng Lin, Ye Chen, Jingwen Zhou, Jingjun Huang, Jiabai Huang, Yaozhu Wu, Wensou Huang, Mingyue Cai

“…Abstract Background Previous studies evaluating antiangiogenic agents plus immune checkpoint inhibitors for unresectable hepatocellular carcinoma (HCC) have shown encouraging results. …”
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TYRO3 blockade enhances anti-PD-1 therapy response by modulating expression of CCN1 in tumor microenvironment by Miso Park, Da-Sol Kuen, Keon Wook Kang, Yeonseok Chung, Jaewoo Park, Munkyung Choi, Yeonji Kim, Eun Chae Roh, Yong June Choi, Yoon Gyoon Kim, Sung Yun Cho

“…Background Immunological contexture differs across malignancies, and understanding it in the tumor microenvironment (TME) is essential for development of new anticancer agents in order to achieve synergistic effects with anti-programmed cell death protein-1 (PD-1) therapy. …”
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Acciones independientes dirigidas al cuidado y promoción de la Diabetes Mellitus en la Atención primaria de salud, apoyada en la teoría de Hildegart Elizabeth Peplau. by Taimi Nereida Rodríguez Abrahantes, Taimy Alfonso Moré, Taimy Alfonso Moré, Arahy Rodríguez Abrahantes, Arahy Rodríguez Abrahantes, Geidy Caridad Cabrera Suris, Geidy Caridad Cabrera Suris, Tamara Lanza Llerena, Tamara Lanza Llerena, Yoan Cepero Santana, Yoan Cepero Santana

“…Los hábitos nutricionales inadecuados (85,71%), el sedentarismo (84,52%) el hábito de fumar (55,38%) fueron los factores de riesgo modificables que más incidieron, más del 60% de la muestra poseían un nivel de información inadecuado sobre la enfermedad y autocuidados; predominaron las relaciones interpersonales evaluadas de aceptables (52,38%). Conclusiones: Se propusieron un conjunto de acciones independientes de enfermería dirigidas al cuidado y promoción de pacientes diabéticos tipo 2 sobre la base de la teoría de las relaciones interpersonales de Hildegart Elizabeth Peplau.…”
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Candidiasis mucocutánea crónica, infecciones micobacterianas y rosácea en un adulto mexicano con aumento de la función en STAT1 by Valeria Valerio-Gómez, Uriel Pérez-Blanco, Guillermo Velázquez-Sámano, Andrea Aída Velasco-Medina, Antonio Albarrán, Itzel Yoselín Sánchez, Laura Berrón-Ruiz, Sara Espinosa-Padilla, Lizbeth Blancas-Galicia

“…La vía de señalización JAK/STAT, mediada por el interferón, participa en la eliminación de agentes patógenos intracelulares y virus. Las variantes patógenas de STAT1 pueden producir una función deficiente o incrementada. …”
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