The Effects of Trenbolone Supplementation on The Extremity Bones in Running Rats by Ali Sarı, Sefa Lök

“…The use of ergogenic agents is increasing among athletes for doping in order to increase physical performance and change external image. …”
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BIOMARCADORES ASEQUIBLES DE DEMENCIA FRONTOTEMPORAL: UN ESTUDIO DE CLASIFICACIÓN BASADO EN LA CONECTIVIDAD DE REDES CEREBRALES by Martín Dottori, Lucas Sedeño, Miguel Martorell Caro, Florencia Alifano, Eugenia Hesse, Ezequiel Mikulan, Adolfo M. García, Marcela Contreras-Torregrosa, Edinson Muñoz, Amparo Ruiz-Tagle, Patricia Lillo, Andrea Slachevsky, Cecilia Serrano, Daniel Fraiman, Agustín Ibáñez

“…Por otra parte, mientras que las pruebas neuropsicológicas llevaron a una discriminación aceptable entre los pacientes con vcDFT y los del grupo control, la adición de los resultados de conectividad aumentó el poder de clasificación. …”
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Effect of phycocyanin and phycoerythrin on antioxidant and antimicrobial activity of refrigerated low-fat yogurt and cream cheese by Azadeh Ahmadi, Seyed Amir Ali Anvar, Bahareh Nowruzi, Leila Golestan

“…This study marks the initial effort to employ PE and PC derived from Nostoc sp. and Spirulina sp. as antioxidant and antimicrobial agents in the food industry.…”
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LA COMPLEJIDAD DE LOS ECOSISTEMAS DEL NORTE DE LA PROVINCIA DE MENDOZA by Moria Alessandro, María Codes, Natalia Pucciarelli, Gabriela Sari, Fernanda Soler, Matias Rodriguez, Jésica Cabanillas, Jorge Fernández

“…Las hipótesis planteadas afirman que, en las escalas de ecosistemas, el clima es el denominador común que organiza la distribución de los mismos; y que existen agentes degradadores en todos los niveles de análisis. …”
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Identification of prognostic biomarker of non-small cell lung cancer based on mitochondrial permeability transition-driven necrosis-related genes and determination of anti-tumor ef... by Zhifei Ma, Wen Chen, Aiping Zhang, Xiaokang Shen, Lin Zheng

“…Correlations between these biomarkers and immune cell infiltration, immune checkpoints, and chemotherapeutic agents were observed. Expression levels of MPTDN-related biomarkers were detected using RT-qPCR in NSCLC tissues and cells. …”
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Possibility of Using NO Modulators for Pharmacocorrection of Endothelial Dysfunction After Prenatal Hypoxia by Igor Belenichev, Olena Popazova, Oleh Yadlovskyi, Nina Bukhtiyarova, Victor Ryzhenko, Sergii Pavlov, Valentyn Oksenych, Oleksandr Kamyshnyi

“…This emphasizes the potential of therapeutic agents with NO modulator properties, such as Thiotriazoline, Angiolin, Mildronate, and L-arginine, in the treatment of PH. …”
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Interaction between Nuclear Receptor and Alpha-Adrenergic Agonist Subtypes in Metabolism and Systemic Hemodynamics of Spontaneously Hypertensive Rats by Sheryar Afzal, Munavvar Abdul Sattar, Ibrahim Albokhadaim, Ali Attiq, Mahmoud Kandeel, Aimi Syamima Abdul Manap, Sameer M. Alhojaily

“…Partial and full PPAR-γ agonists have shown promising effects and antihypertensive and antidiabetic agents through increased plasma adiponectin concentration. …”
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Educación jurídica e innovación tecnológica: un ensayo crítico by Daniel Bonilla Maldonado

“…Las primeras dos respuestas están relacionadas directamente con agentes del mercado que demandan educación jurídica: los estudiantes de derecho y las firmas de abogados. …”
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Clinical perspective on antihypertensive drug treatment in adults with grade 1 hypertension and low to moderate cardiovascular risk: an international expert consultation by Alberto Morales Salinas

“…Una pregunta en debate es si la hipertensión arterial grado 1 (140-159/90-99 mm Hg) con riesgo cardiovascular (RCV) total bajo (mortalidad cardiovascular <1% a los 10 años) a moderado (mortalidad cardiovascular >1% and <5% a los 10 años) debe ser tratada con agentes antihipertensivos. Un proceso de consulta virtual internacional fue realizado para resumir las opiniones de los expertos seleccionados. …”
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Activity of ceftolozane/tazobactam and comparators against gram-negative bacilli: Results from the Study for Monitoring Antimicrobial Resistance Trends (SMART – Brazil), 2018‒2021... by Amanda Azevedo Bittencourt, Vinicius Lima Faustino, Paula de Mendonça Batista, Lays Paulino Leonel, Marina Della Negra de Paula, Thales José Polis

“…Colistin and ceftolozane/tazobactam were the most active β-lactam agents tested against P. aeruginosa in 2018‒2019 (99.3 % and 88.8 %) and 2020‒2021 (100 % and 92.8 %), including ceftazidime and meropenem resistant isolates. β-lactamase encoding gene characterization was carried out and both carbapenemases and Extended-Spectrum β-Lactamase (ESBL) producers were found in E. coli, K. pneumoniae and P. aeruginosa isolates. …”
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Single-cell transcriptomics analysis reveals dynamic changes and prognostic signature in tumor microenvironment of PDAC by Yongsheng Li, Zhilong Ding, Tingxin Cheng, Yihuai Hu, Fei Zhong, Shiying Ren, Shiyan Wang

“…Furthermore, our analysis revealed significant interactions between cells at different stages of PDAC and identified three promising therapeutic agents (XR-11576, Ixabepilone, and AMONAFIDE) based on correlated genes. …”
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Characterization of the fungal genus Sphaerellopsis associated with rust fungi: species diversity, host-specificity, biogeography, and in-vitro mycoparasitic events of S. macroconi... by Paula Andrea Gómez-Zapata, Jorge Ronny Díaz-Valderrama, Samira Fatemi, Cristhian Orlando Ruiz-Castro, M. Catherine Aime

“…Abstract Sphaerellopsis species are putative hyperparasites of rust fungi and may be promising biological control agents (BCA) of rust diseases. However, few detailed studies limit potential BCA development in Sphaerellopsis. …”
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Discovery and development of ANV419, an IL-2/anti-IL-2 antibody fusion protein with potent CD8+ T and natural killer cell-stimulating capacity for cancer immunotherapy by Patrizia Murer, Barbara Brannetti, Jean-Michel Rondeau, Laetitia Petersen, Nicole Egli, Simone Popp, Catherine Regnier, Kirsten Richter, Andreas Katopodis, Christoph Huber

“…These data support the clinical development of ANV419 in solid tumors and hematological malignancies as monotherapy and in combination with checkpoint inhibitors or agents that induce antibody-dependent cellular cytotoxicity. …”
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Synergistic effects of chemical and biochemical fertilization on yield enhancement and oil quality optimization in ‘Zard’ olive cultivars by Mohammad Saeed Tadayon, Ahmad Asgharzadeh, Seyed Majid Mousavi, Kobra Saghafi

“…The second factor, biological fertilizer application (BF), also comprised three levels: BF0 (control), soil-applied organic fertilizer without biological agents; BF1, which included a soil application of an organic fertilizer mix, mycorrhizal fungi, and the beneficial bacteria Bacillus subtilis and Pseudomonas fluorescens, supplemented with fulvic acid and amino acids; and BF1+BFF, where trees were treated with both soil and foliar applications of the aforementioned bacterial species, fulvic acid, and amino acids.ResultsThe CF100+BF1+BFF treatment significantly increased fruit length (31.14%), diameter (41.61%), flesh thickness (30.48%), fresh weight (38.76%), dry weight (55.68%), and yield per tree (27.00%) compared to the control (CF100+BF0). …”
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Ethnopharmocology, phytochemistry and pharmacology of the genus Orthosiphon: A review by Rui Wang, Ling Qiu, Qing-wen Zhang, Ligen Lin

“…Despite substantial bias in attention among various species of the genus Orthosiphon, its potential as health food and therapeutic agents is evident. The genus is an underexplored source of bioactive compounds with potential in various therapeutic areas. …”
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Safety Assessment of Glucose-Lowering Drugs and Importance of Structured Education during Ramadan: A Systematic Review and Meta-Analysis by Rashmi Shiju, Ayesha Akhil, Smitha Thankachan, Jaakko Tuomilehto, Monira Al Arouj, Abdullah Bennakhi

“…The newer class of glucose-lowering agents appear to lower the risk of hypoglycemia in comparison with sulphonylureas, while among sulphonylureas gliclazide is relatively safe. …”
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Small Extracellular Vesicles Secreted by iPSC-Derived MSCs Ameliorate Pulmonary Inflammation and Lung Injury Induced by Sepsis through Delivery of miR-125b-5p by Wei Peng, Yun Yang, Jiaquan Chen, Zeyao Xu, Yuanlei Lou, Qi Li, Ning Zhao, Kejian Qian, Fen Liu

“…Background. Sepsis-induced acute lung injury is a common critical illness in intensive care units with no effective treatment is currently available. …”
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Solitary Nitric Oxide Signaling Mediates Mild Stress-Induced Anxiety and Norepinephrine Release in the Bed Nucleus of the Stria Terminalis during Protracted Ethanol Withdrawal by Zhenglin Zhao, Sang Chan Kim, Yu Jiao, Yefu Wang, Bong Hyo Lee, Hee Young Kim, Chul Won Lee, Chae Ha Yang, Rongjie Zhao

“…In elevated plus maze tests, EtOHW rats but not EtOH-naive rats exhibited anxiety-like behavior when challenged with 7-minute mild restraint stress, which was, respectively, mitigated by prior intra-NTS infusion of the nitric oxide scavenger 2-(4-carboxyphenyl)-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide (carboxy-PTIO), nonselective NOS inhibitor NG-nitro-L-arginine methyl ester (L-NAME), or selective neuronal NOS (nNOS) inhibitor 7-nitroindazole (7-NI). Each of these agents also decreased the plasma corticosterone levels in EtOHW rats. …”
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Antimicrobial effect of silver diamine fluoride (SDF) in arresting dentine caries of permanent teeth: A Systematic review [version 1; peer review: 2 approved] by Mamata Hebbal, Albandri Mohammed Alowid, Praveen Jodalli, Shahad Saad Alkait, Ghadeer Ghalab Almutairi, Fatimah Salim Almufarji

“…The inclusion criteria encompassed studies that compared SDF with other antimicrobial agents, such as sodium fluoride varnish, potassium iodide, silver nitrate, chlorhexidine, plasma jet, and deionized water. …”
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Unveiling the biological activities of Heliotropium indicum L. plant extracts: anti-inflammatory activities, GC–MS analysis, and in-silico molecular docking by Mst. Sadia Afroz Shoily, Md. Ekramul Islam, Nur Mohammad Rasel, Shahnaz Parvin, Jaytirmoy Barmon, Aqibul Hasan Aqib, Debendra Nath Roy, Mst. Shahnaj Parvin

“…Fractionations of crude methanol extract (CME) were undertaken in n-hexane (NHF), chloroform (CHF), and ethyl acetate (EAF). GC–MS analysis was conducted using Agilent technologies. …”
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