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31341
Estasyon Meteyo nan Jaden: Gid pou Enstalasyon ak Antretyen
Published 2019-05-01“…Enstalasyon yon estasyon meteyo bay kiltivatè yo yon opòtinite inik pou yo konprann pi byen kouman chanjman meteyo yo afekte jaden ak betay yo, sepandan, desizyon sa yo dwe baze sou bon kalite obsèvasyon. …”
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31342
Mapping C. difficile TcdB interactions with host cell-surface and intracellular factors using proximity-dependent biotinylation labeling
Published 2025-02-01“…Our work reveals surface receptors and intracellular components exploited by bacterial toxins, highlighting key vulnerabilities in host cells.IMPORTANCEBacterial toxins are the causative agents of many human diseases. Further characterizing the intoxication mechanisms of these proteins is important for the development of vaccines and treatments for toxin-mediated disease. …”
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31343
Relationship between body mass index and clinical events in patients with atrial fibrillation undergoing percutaneous coronary intervention.
Published 2024-01-01“…AF patients who underwent PCI with drug-eluting stents for CAD were retrospectively and prospectively included. …”
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31344
Extracción de fibra dietaria de cáscara de naranja mediante microondas y método convencional: Propiedades macromoleculares y funcionales
Published 2025-01-01“…Con el uso de microondas la fibra presentó mejores propiedades funcionales, como la capacidad de hinchamiento, retención de agua, retención de aceite, y adsorción de colesterol y glucosa. En conclusión, el uso de microondas es un método más eficiente para obtener fibra dietaria de calidad, surgiendo como una alternativa para el aprovechamiento de la cáscara de naranja. …”
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31345
hERG activators exhibit antitumor effects in breast cancer through calcineurin and β-catenin-mediated signaling pathways
Published 2025-01-01“…Notably, combining SDUY429 or SDUY436 with the AKT inhibitor MK-2206 produced synergistic anti-proliferative effects.ConclusionThese findings suggest that hERG activators hold promise as new potential therapeutic agents for the treatment of breast cancer, paving the way for future investigations into their clinical applications.…”
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31346
Chronic Stress Mediates Inflammatory Cytokines Alterations and Its Role in Tumorigenesis
Published 2025-01-01“…This ongoing inflammation further enhances the activity of these transcription factors, which serve multiple roles: they act as pro-inflammatory agents in inflammatory cells, maintaining chronic inflammation; as oncogenic transcription factors in premalignant cells, promoting cancer initiation; and as pro-differentiation transcription factors in tumor-infiltrating immune cells, facilitating cancer progression. …”
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31347
HMOX1 as a potential drug target for upper and lower airway diseases: insights from multi-omics analysis
Published 2025-01-01“…Molecular docking was used to identify potential therapeutic agents. Results HMOX1 expression was significantly elevated in CRSwNP. …”
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31348
Isolation and Evaluation of Clinically Important Acinetobacter Baumannii From Intensive Care Unit Samples
Published 2021-09-01“…However, two antimicrobial agents which were Colistin and Tigecycline produced 0 and 2.4 % resistance to A. baumannii respectively, which were considered the most used choices to treat A. baumannii infections. …”
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31349
Efficacy of Inhaled Steroid Over Systemic Steroid in Stabilizing Acute Asthma in Emergency Room
Published 2025-02-01“…Background: Acute exacerbation of asthma is one of the most common illnesses presenting to Emergency Department. …”
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31350
Contribution of vitamin B 6 deficiency to anemia in children on regular hemodialysis
Published 2025-01-01“…In addition, erythropoiesis-stimulating agents (ESA) and iron supplementation are considered the cornerstones in the management of anemia. …”
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31351
Caracterización de las respuestas relativas de híbridos de girasol en ensayos oficiales del centro y norte de la Argentina
Published 2005-01-01“…Se estimaron los componentes de varianza, se compararon estrategias de selección en función de la heredabilidad en sentido amplio y se aplicaron análisis de patrones sobre matrices de genotipos × ambientes. Para rendimiento de aceite, la interacción G×E explicó 3.46 veces más variabilidad que el efecto genotípico. …”
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31352
Magnetoelectric Extracellular Vesicle Latency-Targeting (MELT) Nanotherapeutic for the Block-Lock-and-Kill HIV Eradication Strategy
Published 2025-01-01“…GFP expression in HC69 at rest is low (GFP<sup>Lo</sup>), and upon exposure to LTR, transcription-activating agents (i.e., TNF-α) are induced to be high expressing (GFP<sup>Hi</sup>). …”
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31353
Phenotypic and Genotypic Identification of Antimicrobial Resistance amongst the Campylobacter jejuni and Campylobacter coli Strains Isolated from Raw Milk of Animal Species
Published 2024-01-01“…The prevalence of simultaneous resistance toward more than 4 antimicrobial agents amongst the C. jejuni and C. coli isolates was 46% and 16.66%, respectively. …”
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31354
The Immunosuppressant Fingolimod (FTY720) for the Treatment of Mechanical Force-Induced Abnormal Scars
Published 2020-01-01“…Therefore, its local immunosuppressive mechanisms differ from those of conventional immunosuppressive agents. Topical FTY720 can be a novel therapeutic option for abnormal scars that are difficult to control with corticosteroids. …”
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31355
Contrast Medium Use in Computed Tomography for Patients Presenting with Headache: 4-year Retrospective Two-Center Study in Central and Western Regions of Ghana
Published 2022-01-01“…Further studies to improve the knowledge of agents, mechanism of action, and safety of contrast media used among practitioners in Ghana is recommended.…”
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31356
Cytotoxic mechanisms of pemetrexed and HDAC inhibition in non-small cell lung cancer cells involving ribonucleotides in DNA
Published 2025-01-01“…HDAC inhibition apparently exacerbates cytotoxicity of these agents by inhibiting error-free repair of misincorporated ribonucleotides in DNA. …”
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31357
Structural and free energy landscape analysis for the discovery of antiviral compounds targeting the cap-binding domain of influenza polymerase PB2
Published 2024-10-01“…These findings suggest that compound 4, along with compounds 1 and 3, holds the potential for further development into effective antiviral agents against influenza. Future studies should focus on experimental validation of these compounds and exploration of resistance mechanisms to enhance their therapeutic utility.…”
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31358
Evaluación del programa de la disciplina Morfofisiología Humana en la formación del tecnólogo en Electromedicina
Published 2014-04-01“…<strong>Fundamento</strong>: En la disciplina Morfofisiología Humana surgen una serie de interrogantes en relación con el programa de estudio, los cuales se manifiestan en los diferentes espacios docentes y metodológicos, tanto a través del análisis del trabajo metodológico materializado en la disciplina como de los agentes implicados en el proceso de enseñanza-aprendizaje.…”
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31359
Fondo regional en América Latina y el Caribe para el desarrollo económico local y los gobiernos locales: Estrategia para la reducción de la pobreza y de la desigualdad social
Published 2006-01-01“…Los proyectos que serán implementados a través del Fondo Regional deben contribuir a la afirmación de una identidad, de elementos distintos, de una reputación propia, de características singulares que diferencien lo local dentro del universo de la globalización y que encuentran las ventajas comparativas de lo local frente a la competitividad territorial a nivel global. La formación de agentes multiplicadores en las diferentes municipalidades debe tener como eje central, la descubierta, el reconocimiento y la valorización de los activos locales, esto significa, de las potencialidades, vocaciones, oportunidades, ventajas comparativas y competitivas de cada territorio para el desarrollo económico local. …”
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31360
Oralidad y enseñanza-aprendizaje del francés a hispanohablantes
Published 2005-01-01“…En efecto, frente a la lógica de la física, se inscribe en la lógica de lo viviente: las variables y parámetros que adopta permiten determinar el sistema de errores (efectivos o latentes) sin exigir ni presuponer conductas fonatorias predeterminadas; antes bien inducen a que el aprendiente consiga resultados aceptables utilizando sus propias aptitudes y facultades personales (que, por lo demás, no pueden ser conocidas a priori). …”
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