Environmental Hazard of Polypropylene from Disposable Face Masks Linked to the COVID-19 Pandemic and Its Possible Mitigation Techniques through a Green Approach by Selvakumar Vijayalakshmi, Preethi Gopalsamy, Karnan Muthusamy, Dinesh Kumar Sundarraj, Steffi Pulikondan francis, Thiyagarajan Ramesh, Deog-Hwan Oh, Duong Ly Thi Thuy, Tuyet Thi Anh Truong, Huu Tap Van, Shankar Karuppannan

“…The methods and strain presented here reveal the potential biodegrading agents of PP masks.…”
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Protective Effect of Liposome-Encapsulated Glutathione in a Human Epidermal Model Exposed to a Mustard Gas Analog by Victor Paromov, Sudha Kumari, Marianne Brannon, Naga S. Kanaparthy, Hongsong Yang, Milton G. Smith, William L. Stone

“…Sulfur mustard or mustard gas (HD) and its monofunctional analog, 2-chloroethyl ethyl sulfide (CEES), or “half-mustard gas,” are alkylating agents that induce DNA damage, oxidative stress, and inflammation. …”
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Mixture of Bacillus Amyloliquefaciens and Bacillus Pumilus Modulates Community Structures of Rice Rhizosphere Soil to Suppress Rice Seedling Blight by Jiang Nan, Qiu Jiehua, Tian Dagang, Shi Huanbin, Liu Zhiquan, Wen Hui, Xie Shuwei, Chen Huizhe, Wu Meng, Kou Yanjun

“…As awareness grows regarding the environmental and safety hazards associated with the application of fungicides for managing rice seedling blight, there has been a shift in focus towards biological control agents. In this study, we isolated biocontrol bacteria from paddy fields that significantly inhibited the growth of F. oxysporum in vitro and identified the strains as Bacillus amyloliquefaciens T40 and Bacillus pumilus T208. …”
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Co-Localized in Amyloid Plaques Cathepsin B as a Source of Peptide Analogs Potential Drug Candidates for Alzheimer’s Disease by Marilena K. Theodoropoulou, Konstantina D. Vraila, Nikos C. Papandreou, Georgia I. Nasi, Vassiliki A. Iconomidou

“…These findings point out the potential of APR-derived peptide analogs from co-localized proteins as innovative agents against AD, paving the way for further exploration in peptide-based therapeutic development.…”
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Biopreservation of Shrimps Using Composed Edible Coatings from Chitosan Nanoparticles and Cloves Extract by Ahmed A. Tayel, Aml F. Elzahy, Shaaban H. Moussa, Mohammed S. Al-Saggaf, Amany M. Diab

“…The synthesized CLE/Cht-NPs were electrostatically cross-linked and appeared with spherical shapes and homogenized distribution, with 159.4 nm mean size diameter and positive charge of 17.4 mV. The entire agents (Cht-NPs, CLE, and CLE/Cht-NPs) exhibited remarkable antibacterial activities toward all food-borne pathogens; CLE/Cht-NPs were significantly the most forceful. …”
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CHIP away at the marrow-clot connection: inflammation, clonal hematopoiesis, and thromboembolic disease by Angela Todorovski, Tzu-Fei Wang, Marc Carrier, Yan Xu

“…However, canakinumab showed promise in a post-hoc analyses of patients with TET2-mutated CHIP, and other anti-inflammasome agents are actively under development or evaluation. …”
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Diagnosis and Management of Acquired Hemophilia A: Case Reports and a Literature Review by Ikhwan Rinaldi, Findy Prasetyawaty, Siti Fazlines, Kevin Winston, Yusuf Aji Samudera Nurrobi, Jessica Leoni, Ilham Hidayat Restu Tulus Maha, Satrio Wicaksono, Abdillah Yasir Wicaksono, Averina Octaxena Aslani, Rizkania Ikhsani

“…Treatment consists of factor VIII transfusion and corticosteroid therapy. Bypassing agents are recommended as an alternative to FVIII transfusion.…”
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Neuropeptides SP and CGRP Diminish the Moraxella catarrhalis Outer Membrane Vesicle- (OMV-) Triggered Inflammatory Response of Human A549 Epithelial Cells and Neutrophils by Daria Augustyniak, Justyna Roszkowiak, Izabela Wiśniewska, Jacek Skała, Daiva Gorczyca, Zuzanna Drulis-Kawa

“…Moraxella catarrhalis is one of the leading infectious agents responsible for inflammatory exacerbation in chronic obstructive pulmonary disease (COPD). …”
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Autoimmune pulmonary alveolar proteinosis developed during treatment for systemic sclerosis: a case report by Tomoki Kozono, Kentaro Tanaka, Tomoko Yagi, Kazuto Kamikawaji, Masaki Watanabe, Azusa Iwanaga, Minako Hamada, Yoshifusa Koreeda, Hiromasa Inoue, Ikkou Higashimoto

“…Here, we describe a rare case of a patient with systemic sclerosis who was diagnosed with APAP after the exacerbation of lung opacities during treatment with immunosuppressive agents. Case presentation A 72-year-old woman was diagnosed with systemic sclerosis (SSc) at the age of 68, and initiated treatment with prednisolone (PSL). …”
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Tumor organoids in cancer medicine: from model systems to natural compound screening by Rong Cong, Can Lu, Xinying Li, Zhijie Xu, Yaqin Wang, Shusen Sun

“…Recent studies utilizing patient-derived organoid models for natural compound screening are highlighted, demonstrating the potential of these models in developing new classes of anticancer agents. The integration of natural products with patient-derived organoid models presents a promising approach for discovering novel anticancer compounds and elucidating their mechanisms of action.…”
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Modulation of Apoptosis and ER Stress Markers in Hepatocellular Carcinoma Cells by Irinotecan, Hesperidin, and Piperine by Serkan Sen, Kardelen Kocaman Kalkan, Canan Yilmaz, Sefa Celik

“…These findings highlight complex interactions between chemotherapeutic agents and natural compounds, warranting further exploration in combination therapies.…”
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Expression of O6-Alkylguanine-DNA Alkyltransferase in Normal and Malignant Bladder Tissue of Egyptian Patients by Abir A. Saad, Heba Sh. Kassem, Andrew C. Povey, Geoffrey P. Margison

“…Based on this, bladder cancers would be expected to be relatively resistant to chemotherapy which involved O6-guanine alkylating antitumour agents.…”
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The Molecular Diagnosis Protocols of New Coronavirus (COVID-19); Specificity and Sensitivity an Overview by Abdullah Ahmed Hama, Othman Abdulrahman Mohammed, Fatima Mahmud Ali, Osama Hamid Shareef, Sardar Muhammad Wli, Sabiha Sharif, Syamand Ahmed Qadir

“…Acute respiratory tract infection is a common public health concern worldwide a new emerging contagious virus (COVID-2019) or SARSC- 2 causing a pandemic pneumonia outbreak, The main transmission route of this virus is through droplets from respiratory made during sneezing or coughing of infected people like the recent viral infection of severe acute respiratory syndrome (SARS-CoV1) and the Middle East respiratory syndrome (MERS). …”
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CHOLANGIOCARCINOMA: EPIDEMIOLOGY, HISTOPATHOLOGY, AND POTENTIAL PROGNOSTIC AND THERAPEUTIC IMPLICATIONS IN A COHORT FROM A REFERENCE CENTER IN SOUTHERN BRAZIL by João Pedro Pattussi BERTINATTI, Josenel Maria Barcelos MARÇAL, Eduardo CAMBRUZZI, Dido Eliphas LEÃO DE ALENCAR

“…METHODS: This is a retrospective study of the clinical and histological data of patients diagnosed with CCA at Santa Casa de Misericórdia in Porto Alegre, Brazil, between 2016 and 2021. RESULTS: There was a 56% prevalence of CCA in women, with intrahepatic localization in 55.4% of cases and unifocality in 85.6% of patients. …”
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Protective Effects of Chitosan Oligosaccharide Against Lipopolysaccharide-Induced Inflammatory Response and Oxidative Stress in Bovine Mammary Epithelial Cells by Ziwei Lin, Yanlong Zhou, Ruiwen Chen, Qiuyan Tao, Qiwen Lu, Qianchao Xu, Haibin Yu, Ping Jiang, Zhihui Zhao

“…In summary, the results demonstrate that the protective mechanism of COS on the LPS-induced inflammatory response and oxidative stress depend on the TLR4/nuclear factor-κB (NF-κB) and Nrf2 signaling pathways, indicating that COS could serve as natural protective agents for alleviating BMECs in mastitis.…”
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Measuring Lp(a) particles with a novel isoform-insensitive immunoassay illustrates efficacy of muvalaplin by Craig A. Swearingen, John H. Sloan, Grace M. Rhodes, Robert W. Siegel, Nico Bivi, Yuewei Qian, Robert J. Konrad, Michael Boffa, Marlys Koschinsky, John Krege, Giacomo Ruotolo, Stephen J. Nicholls, Laura F. Michael, Yi Wen

“…This novel intact Lp(a) assay provides a more accurate approach for the assessment of Lp(a)-lowering agents and the study of Lp(a)-associated risk compared with currently available assays.…”
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Transitioning from Oxime to the Next Potential Organophosphorus Poisoning Therapy Using Enzymes by Rauda A. Mohamed, Keat K. Ong, Noor Azilah M. Kasim, Norhana A. Halim, Siti Aminah M. Noor, Victor F. Knight, Nurul Najwa Ab. Rahman, Wan Md Zin W. Yunus

“…For years, organophosphorus poisoning has been a major concern of health problems throughout the world. An estimated 200,000 acute pesticide poisoning deaths occur each year, many in developing countries. …”
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Helicobacter pylori promotes intestinal flora imbalance and hepatic metabolic disorders under arsenic stress by Linmin Zhong, Qiling Yang, Yiming Shao, Shanwen Hu, Lianxian Guo

“…This results in an increasing population at risk of simultaneous exposure to both harmful agents, yet whether a synergistic interaction exists between them remains unclear. …”
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Nasal Carriage of Methicillin-Resistant Staphylococcus aureus among Health Care Workers in Tertiary and Regional Hospitals in Dar es Salam, Tanzania by Agricola Joachim, Sabrina J. Moyo, Lillian Nkinda, Mtebe Majigo, Sima Rugarabamu, Elizabeth G. Mkashabani, Elia J. Mmbaga, Naboth Mbembati, Said Aboud, Eligius F. Lyamuya

“…In conclusion, we found a high nasal carriage of MRSA and resistance to commonly prescribed antimicrobial agents among HCWs. Implementation of infection control measures including contact precautions, urgent reporting of MRSA laboratory results, and routine MRSA screening of HCWs is highly needed to reduce MRSA spreading.…”
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Hydrogen Generation from the Hydrolysis of Diamond-Wire Sawing Silicon Waste Powder Vibration-Ground with KCl by Zhicheng Li, Tao Zhou, Jiangfan Liao, Xiufeng Li, Wenhui Ma, Guoqiang Lv, Shimin Zhao

“…Among the studied grinding agents, KCl has the best performance. The grinding duration and addition amount remarkably affect the final hydrogen yield and initial hydrogen generation rate (IHGR). …”
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