Methodology to Evaluate Dripper Sensitivity to Clogging due to Solid Particles: An Assessment by Rogério Lavanholi, Fabricio C. Oliveira, Antonio P. de Camargo, José A. Frizzone, Bruno Molle, Nassim Ait-Mouheb, Séverine Tomas

“…Emitter clogging is a major problem in microirrigation systems, which may result from the isolated or combined effects of physical, chemical, and biological agents. Clogging caused by suspended solid particles is the most common plugging form of emitters. …”
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Effects of brain renin- angiotensin system inhibition in ISIAH rats with inherited stress-induced arterial hypertension by L. O. Klimov, M. A. Ryazanova, L. A. Fedoseeva, A. L. Markel

“…Inhibition was performed using widely used pharmacological agents, losartan and benazepril. Osmotic minipumps were used to deliver drugs to the lateral ventricle of the brain. …”
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Biochemical Constituents of Phaleria macrocarpa (Leaf) Methanolic Extract Inhibit ROS Production in SH-SY5Y Cells Model by Ibrahim Maina Hassan, Wan Norhamidah Wan Ibrahim, Ferdaus Binti Mohamat Yusuf, Siti Aqlima Ahmad, Syahida Ahmad

“…Several studies show that ROS is incriminated as destructive agents in the context of the nervous system especially with advance in age leading to neurodegeneration. …”
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EİNSTEİN’A GÖRE BİLİM, DİN VE FELSEFE: DİN FELSEFESİ AÇISINDAN BİR ÇÖZÜMLEME by Şahin Efil

“…Albert Einstein, filozof-bilim adamı modelinin en önde gelen örneklerindenbirisidir. …”
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Sex-based differences in lung cancer susceptibility and molecular genetics in the 2020s by Berta Mosleh, Pavla Sarova, Sonja Zehetmayer, Felicitas Oberndorfer, Joachim Widder, Helmut Prosch, Marco Idzko, Clemens Aigner, Mir Alireza Hoda, Daniela Gompelmann

“…Objective: The objective of the current study was to reveal timely sex-based differences in patients with lung cancer in the era of immunotherapy and molecularly targeted agents. Methods: We retrospectively analyzed a consecutive cohort of 286 patients (female:male ratio 134:152/47 %:53 %) who were diagnosed with lung cancer between 2020 and 2022 in the pulmonology department of the Medical University of Vienna, Austria. …”
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Subgingival Delivery of Statins as an Adjunct in the Non-Surgical Treatment of Periodontitis: A Systematic Review by Magdalena Maria Pietrzko, Maciej Pietrzko, Wojciech Niemczyk, Dariusz Skaba, Rafał Wiench

“…Conclusions: This literature review led the authors to the conclusion that statins applied locally might be competent agents for improving the therapeutic outcomes of SRP.…”
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Pharmacological insights and therapeutic advances of mangiferin against various pathological conditions in liver diseases by Tanvir Zaman Shoyshob, Sumaya Akter, Muhammad Ramiz Uddin, Mithila Farjana, Akhi Moni, Wonhyo Seo, Md. Golzar Hossain, Md Jamal Uddin

“…Currently, liver diseases have become a serious global health issue, and this situation occurs due to the exposure of the liver to different agents, such as chemicals, alcohol, viruses, and autoimmune diseases. …”
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A Comparison between the Effects of Glucantime, Topical Trichloroacetic Acid 50% plus Glucantime, and Fractional Carbon Dioxide Laser plus Glucantime on Cutaneous Leishmaniasis Les... by Fariba Jaffary, Mohammad Ali Nilforoushzadeh, Amirhossein Siadat, Elaheh Haftbaradaran, Nazli Ansari, Elham Ahmadi

“…However, the cure rate of these agents is still not favorable. This study was carried out to compare the efficacies of intralesional glucantime with topical trichloroacetic acid 50% (TCA 50%) + glucantime and fractional carbon dioxide laser + glucantime in the treatment of cutaneous leishmaniasis. …”
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Improving Implementation of NCD Care in Low- and Middle-Income Countries: The Case of Fixed Dose Combinations for Hypertension in Kenya by Adrianna Murphy, Daniel Mbuthia, Ruth Willis, Benjamin Tsofa, Mary Gichagua, Peter Mugo, Kara Hanson, Michael R. Reich

“…Included in WHO’s Essential Medicines List, FDCs combine two or more blood pressure lowering agents into one pill and can reduce burden on patients and the health system. …”
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Proteomic Characterization of Liver Cancer Cells Treated with Clinical Targeted Drugs for Hepatocellular Carcinoma by Hezhou Long, Jiafu Zhou, Changxia Zhou, Shuyu Xie, Jingling Wang, Minjia Tan, Junyu Xu

“…<b>Methods</b>: In this study, we utilized a Tandem Mass Tag (TMT)-based quantitative proteomic approach to analyze global protein expression and serine/threonine/tyrosine (S/T/Y) phosphorylation modifications in HepG2 cells following treatment with three clinically relevant hepatocellular carcinoma-targeted agents: apatinib, regorafenib, and lenvatinib. <b>Results</b>: Utilizing KEGG pathway enrichment analysis, biological process enrichment analysis, and protein interaction network analysis, we elucidated the common and specific metabolic pathways, biological processes, and protein interaction regulatory networks influenced by three liver cancer therapeutics. …”
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Devising Yorùbá Terminology for Phonology Terms (from letter P to letter R) by Oyetayo A Bankale, Oye Taiwo, Rukayat Olawale

“…Some of the terms developed are palatalization, ìso̩dàfàjàpè, paragoge ìfìró-bò̩parí, parasitic harmony àǹkóò àfòmó̩, parse ìpínsífó̩rán-ìhun, partial overlapping ìwo̩nú-ara e̩lé̩be̩, phonaestheme fóníìmù-àyo̩túnyo̩, phonemic overlapping ìpòórá fóníìmù, phonological phrase boundary ààlà àpólà fonó̩ló̩jì, phonological prime fó̩nrán-akérépin fonó̩ló̩jì, quantity-sensitive feet è̩wo̩n-atéńté aníwò̩n-agbe̩gé̩, recessive vowel fáwè̩lì àdínkù, redundancy rule òfin aléélè̩ [1] See Yoruba – The Journal of Yoruba Studies Association of Nigeria, Volume 12:1, January 2023 and Volume 12:2, June 2023 for the first 2 of the four-part essays. …”
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Testing and identification of bovine viral diarrhea virus isolates recovered in Russia between 2019 and 2022 by R. I. Bubyakin, S. V. Kononova, I. N. Shumilova, O. P. Byadovskaya, A. O. Krotova, A. V. Kononov

“…Studying the agents of bovine viral diarrhea (BVD) is an important task given the high probability of new isolate introduction into the Russian Federation, as well as the need to take into account the genotype and subgenotype of the virus circulating in a herd when developing vaccines and diagnostic kits for the infection. …”
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Exploring anti-cancer activities of epidermal growth factor-immobilized polymeric nanoparticles by Shota Yamamoto, Chia-Jung Chang, Masao Kamimura, Jun Nakanishi

“…Cytotoxic agents targeting the epidermal growth factor receptor (EGFR) exhibit significant potential for cancer therapy as EGFR is overexpressed in various cancers. …”
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Spireoside Controls Blast Disease by Disrupting Membrane Integrity of Magnaporthe oryzae by Xu Liting, He Kaiwei, Guo Chunyu, Quan Cantao, Ma Yahuan, Zhang Wei, Ren Lifen, Wang Long, Song Li, Ouyang Qing, Yin Junjie, Zhu Xiaobo, Tang Yongyan, He Min, Chen Xuewei, Li Weitao

“…The application of fungicides is an effective strategy for controlling plant diseases. Among these agents, plant-derived antifungal metabolites are particularly promising due to their eco-friendly and sustainable nature. …”
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A novel proficiency test to assess the animal diagnostic investigation process in identifying an unknown toxicant by Andriy Tkachenko, Yang Chen, Marissa Petrey, Scott Fritz, Tim Walsh, David Rotstein, Megan R. Miller, Bruce Williams, Michael Dark, Matthew Kmet, Ravinder Reddy, Gregory Tyson, Sarah M. Nemser

“…In a typical chemistry PT, blind-coded samples are sent to participants for analysis of specific chemical agents, and results are compared to a pre-determined key (e.g., expected concentrations) to assess proficiency. …”
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Decitabine Compared with Low-Dose Cytarabine for the Treatment of Older Patients with Newly Diagnosed Acute Myeloid Leukemia: A Pilot Study of Safety, Efficacy, and Cost-Effectiveness by Linu A. Jacob, S. Aparna, K. C. Lakshmaiah, D. Lokanatha, Govind Babu, Suresh Babu, Sandhya Appachu

“…Introduction. The incidence of Acute Myeloid Leukemia (AML) increases progressively with age and its treatment is challenging. …”
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SGLT2i and GLP-1RA in Cardiometabolic and Renal Diseases: From Glycemic Control to Adipose Tissue Inflammation and Senescence by Luis D'Marco, Valery Morillo, José Luis Gorriz, María K. Suarez, Manuel Nava, Ángel Ortega, Heliana Parra, Nelson Villasmil, Joselyn Rojas-Quintero, Valmore Bermúdez

“…Concerning the latter, the individual or associated use of these antihyperglycemic agents has been linked with a decrease in proinflammatory cytokines and with an improvement in the inflammatory profile in chronic endocrine-metabolic diseases. …”
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Impact of Age and Sex on Viral Load in Hepatitis C Virus Infection by Andrea Magri, Giulia Francesca Manfredi, Carlo Smirne, Silvia Pigni, Michela Emma Burlone, Mattia Bellan, Nicole Vercellino, Rosalba Minisini, Mario Pirisi

“…<i>n</i> = 922 patients (males <i>n</i> = 497, median age 62 years), all naïve to direct antiviral agents, were studied. Females were older (median age 68 vs. 57, <i>p</i> < 0.001) and had a higher prevalence of genotype 2 (33% vs. 20%, <i>p</i> < 0.001) than males; there was no difference between sexes regarding the METAVIR stage. …”
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G Protein-Coupled Estrogen Receptor-Selective Ligands Modulate Endometrial Tumor Growth by Whitney K. Petrie, Megan K. Dennis, Chelin Hu, Donghai Dai, Jeffrey B. Arterburn, Harriet O. Smith, Helen J. Hathaway, Eric R. Prossnitz

“…Here, employing ERα-negative Hec50 endometrial cancer cells, we demonstrate that GPER mediates estrogen-stimulated activation of ERK and PI3K via matrix metalloproteinase activation and subsequent transactivation of the EGFR and that ER-targeted therapeutic agents (4-hydroxytamoxifen, ICI182,780/fulvestrant, and Raloxifene), the phytoestrogen genistein, and the “ERα-selective” agonist propylpyrazole triol also function as GPER agonists. …”
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Immunological Dynamics Associated with Direct-Acting Antiviral Therapies in Naive and Experimented HCV Chronic-Infected Patients by Grenda Leite Pereira, Andréa Monteiro Tarragô, Walter Luiz Lima Neves, Pedro Vieira da Silva Neto, Priscila Sarmento de Souza, Juliana dos Santos Affonso, Keyla Santos de Sousa, Jéssica Albuquerque da Silva, Allyson Guimarães Costa, Flamir da Silva Victoria, Marilu Barbieri Victoria, Adriana Malheiro

“…The therapeutic strategies used in the treatment of hepatitis C are essentially based on the combination of direct-acting antiviral agents (DAAs). This therapy has been shown to be very effective in relation to patient adherence to treatment and has shown high rates of sustained virological response (SVR). …”
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