The Antiseptic Octenidine Inhibits Langerhans Cell Activation and Modulates Cytokine Expression upon Superficial Wounding with Tape Stripping by Nenad Nikolić, Philip Kienzl, Pooja Tajpara, Martin Vierhapper, Johannes Matiasek, Adelheid Elbe-Bürger

“…Ideal agents for the topical treatment of skin wounds should have antimicrobial efficacy without negative influence on wound healing. …”
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A Refined Nomenclature System to Better Discriminate Endo- and Exo-Type Fructanases and Glucanases by Laura Leaerts, Jaime Ricardo Porras-Domínguez, Maxime Versluys, Wim Van den Ende

“…Our refined nomenclature system will advance enzyme structure–function research and support the production and application of fructan and glucan oligosaccharides as prebiotics, priming agents, and potential signaling molecules in microbe–microbe and plant–microbe interactions. …”
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Extracellular Vesicles of Mesenchymal Stem Cells Are More Effectively Accessed through Polyethylene Glycol-Based Precipitation than by Ultracentrifugation by Lei Jia, Bo Li, Cong Fang, Xiaoyan Liang, Yingjun Xie, Xiaofang Sun, Wen Wang, Lei Zheng, Ding Wang

“…Extracellular vesicles (EVs) have been identified as cell-cell communication agents, and EVs derived from mesenchymal stem cells (MSCs) exhibit therapeutic effects similar to those of the cells of origin. …”
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Glutaraldehyde-Polymerized Hemoglobin: In Search of Improved Performance as Oxygen Carrier in Hemorrhage Models by Anca D. Farcas, Vlad Al Toma, Ioana Roman, Bogdan Sevastre, Florina Scurtu, Radu Silaghi-Dumitrescu

“…Here, such HBOCs are tested in a hemorrhage set-up; ovine hemoglobin is also tested for the first time in such a setting, based on in vitro data showing its improved performance versus bovine Hb against oxidative and nitrosative stress agents. Indeed, ovine Hb performs better than bovine Hb in terms of survival rates, arterial tension, immunology, and histology. …”
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Indoor air quality at the Arab governmental girls’ schools [version 2; peer review: 2 approved, 1 approved with reservations] by Abdulmalik Salman Alsaif, Mohammed Tawfiq Aljassim, Sana Abdullah Alsulaiman, Mahmoud Fathy Elsharkawy

“…The physical school environment includes the physical structures; presence of chemicals and biological agents; and the surrounding environment, including air, water, and materials. …”
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Deoxycholate, an Endogenous Cytotoxin/Genotoxin, Induces the Autophagic Stress-Survival Pathway: Implications for Colon Carcinogenesis by Claire M. Payne, Cheray Crowley-Skillicorn, Hana Holubec, Katerina Dvorak, Carol Bernstein, Mary Pat Moyer, Harinder Garewal, Harris Bernstein

“…It was concluded that the activation of autophagy by DOC has important implications for colon carcinogenesis and for the treatment of colon cancer in conjunction with commonly used chemotherapeutic agents.…”
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Physiological and Antagonistic Properties of Pichia kluyveri for Curative and Preventive Treatments Against Post-Harvest Fruit Fungi by Maxwell Mewa Ngongang, Heinrich Wilbur Du Plessis, Chidi Silas Boredi, Ucrecia Faith Hutchinson, Karabo Seteno Obed Ntwampe, Vincent Ifeanyi Okudoh, Neil Paul Jolly

“…The replacement of these chemicals by safer and cost- effective biocontrol agents is now a priority. This study investigated the physiological characteristics of Pichia kluyveri and its potential use as a biofungicide. …”
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Evaluation of polyphenol and antioxidant properties of Blumea balsamifera extract as potential therapeutic for breast cancer by Kamila Fairuz Sarah, Annisa Yuslinda, Rosyadah Nuraini, Hermanto Feri Eko, Widyananda Muhammad Hermawan, Dwijayanti Dinia Rizqi, Widodo Nashi

“…Hence, this study evaluates the active compounds in extract and their potential as therapeutic agents for breast cancer. The total phenolic and flavonoid content was determined based on quantified colourimetry analysis followed by DPPH assay to evaluate antioxidant activity and phytochemicals screening in the extract, which was characterised by LC-HRMS analysis. …”
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Analytical Method Development for Sodium Valproate through Chemical Derivatization by Murad Abualhasan, Nihaya Wasif Odeh, Ghadeer Naser Younis, Oyoun Fadel Zeidan

“…The reaction used was estrification reaction using coupling agents. An analytical method was then developed and validated using reverse-phase HPLC. …”
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Patterns of Antimicrobial Resistance in the Causative Organisms of Spontaneous Bacterial Peritonitis: A Single Centre, Six-Year Experience of 1981 Samples by Sara Sheikhbahaei, Alireza Abdollahi, Nima Hafezi-Nejad, Elham Zare

“…This study aims to determine the microbial agents of SBP and the pattern of antibiotic resistance, in a large number of ascitic samples. …”
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Antimicrobial Doses in Continuous Renal Replacement Therapy: A Comparison of Dosing Strategies by Anna P. Kempke, Abbie S. Leino, Farzad Daneshvar, John Andrew Lee, Bruce A. Mueller

“…Full pharmacokinetic data was available for 18, 31, and 40 agents using acute kidney injury, end stage renal disease, and normal patient data, respectively. …”
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Effect of pig serum storage conditions on detection of anti-ASFV antibodies by ELISA by A. R. Shotin, I. Yu. Zhukov, A. S. Pershin, Ali Mazloum, I. V. Shevchenko, A. S. Igolkin, O. A. Manuylova, K. N. Gruzdev

“…Although the results of detection of antibodies against the agents of some diseases cannot be used in case of other pathogens, this study has a substantial applied significance as it allows to specify the dependence of the valid results of ASF serodiagnosis on the storage conditions of the samples.…”
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Novel drug targets for monkeypox: From viral to host proteins by Zhaozhong Zhu, Qin Sun, Yunhai Xu, Youya Niu, Fei Yang, Shuidong Feng

“…Further analysis revealed 31 MMIPs as potential targets for broad-spectrum antiviral agents, supported by their involvement in other viral interactions. …”
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Absence of Rejection in a Facial Allograft Recipient with a Positive Flow Crossmatch 24 Months after Induction with Rabbit Anti-Thymocyte Globulin and Anti-CD20 Monoclonal Antibody by Bruce E. Gelb, J. Rodrigo Diaz-Siso, Natalie M. Plana, Adam Jacoby, William J. Rifkin, Kimberly S. Khouri, Daniel J. Ceradini, Eduardo D. Rodriguez

“…As of posttransplant month 24, the patient has not developed acute rejection or metabolic or infectious complications. …”
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Management of Wet Age-Related Macular Degeneration in Spain: Challenges for Treat and Extend Implementation in Routine Clinical Practice by A. García-Layana, J. García-Arumí, M. S. Figueroa, L. Arias Barquet, J. M. Ruíz-Moreno, L. Monclús-Arbona, The Spanish AMD Multicenter Group

“…The use of anti-VEGF agents with longer duration of action could facilitate the use of strict T&E approaches according to routine clinical practices.…”
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The Antibiotic Resistance Profiles of Bacterial Strains Isolated from Patients with Hospital-Acquired Bloodstream and Urinary Tract Infections by Hamed Ghadiri, Hamid Vaez, Samira Khosravi, Ebrahim Soleymani

“…The present study showed that CoNS and E. coli are the most common causative agents of nosocomial BSIs and UTIs, and control of infection needs to be addressed in both antibiotic prescription and general hygiene.…”
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Monoclonal anti-CD38 therapy in human myeloma: retrospects and prospects by Alberto L. Horenstein, Angelo C. Faini, Angelo C. Faini, Fabio Morandi, Erika Ortolan, Paola Storti, Nicola Giuliani, Nicola Giuliani, Paul G. Richardson, Fabio Malavasi, Fabio Malavasi

“…The goal is to identify new agents whose unique properties may enhance tumor eradication. …”
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New Treatments for Bacterial Keratitis by Raymond L. M. Wong, R. A. Gangwani, Lester W. H. Yu, Jimmy S. M. Lai

“…Broad spectrum antibiotics have been the main stay of treatment for bacterial keratitis but with the emergence of bacterial resistance; there is a need for newer antimicrobial agents and treatment methods. Fourth-generation fluoroquinolones and corneal collagen cross-linking are amongst the new treatments. …”
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Anti-Inflammatory and Prebiotic Potential of Ethanol Extracts and Mucilage Polysaccharides from Korean Yams (<i>Dioscorea polystachya</i> and <i>Dioscorea bulbifera</i>) by So-Yoon Park, Van-Long Truong, Su-Gyeong Jeon, So-Young Choe, Razanamanana H. G. Rarison, Byoung-Hoon Yoon, Ji-Won Park, Hye-Jeong Jeong, Woo-Sik Jeong

“…These findings highlight the bioactive potential of ethanol extracts and mucilage polysaccharides from Korean yams, emphasizing their promising applications as anti-inflammatory, immune-modulating, and prebiotic agents for functional food and nutraceutical development.…”
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Ferroan Dolomitization by Seawater Interaction with Mafic Igneous Dikes and Carbonate Host Rock at the Latemar Platform, Dolomites, Italy: Numerical Modeling of Spatial, Temporal,... by K. Blomme, S. J. Fowler, P. Bachaud, F. H. Nader, A. Michel, R. Swennen

“…Results confirm that seawater becomes Fe-enriched during interaction with clinopyroxene (diopside-hedenbergite) and plagioclase (anorthite-albite-orthoclase) solid solutions. Reaction of modified seawater with limestone causes ferroan and nonferroan replacement dolomitization. …”
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