Preparation and Antibacterial Properties of Substituted 1,2,4-Triazoles by Ionuţ Ledeţi, Vasile Bercean, Anda Alexa, Codruţa Şoica, Lenuţa-Maria Şuta, Cristina Dehelean, Cristina Trandafirescu, Delia Muntean, Monica Licker, Adriana Fuliaş

“…The evaluation of biological activities showed that the compounds act as antibacterial agents against Staphylococcus aureus (ATCC 25923), while being inactive against Escherichia coli (ATCC 25922) and Pseudomonas aeruginosa (ATCC 27853). …”
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Passive Immunoprophylaxis for the Protection of the Mother and Her Baby: Insights from In Vivo Models of Antibody Transport by Yanqun Xu, Iftekhar Mahmood, Lilin Zhong, Pei Zhang, Evi B. Struble

“…Vertical transmission of infectious agents, such as Zika, hepatitis B, and cytomegalovirus during pregnancy, remains a public health problem, associated with dire outcomes for the neonate. …”
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Contribution of Statins towards Periodontal Treatment: A Review by Catherine Petit, Fareeha Batool, Isaac Maximiliano Bugueno, Pascale Schwinté, Nadia Benkirane-Jessel, Olivier Huck

“…Moreover, combination of statin therapy with other regenerative agents improves periodontal healing response. Therefore, statins could be proposed as a potential adjuvant to periodontal therapy. …”
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Mesenchymal Stem/Stromal Cells from Discarded Neonatal Sternal Tissue: In Vitro Characterization and Angiogenic Properties by Shuyun Wang, Lakshmi Mundada, Eric Colomb, Richard G. Ohye, Ming-Sing Si

“…Autologous and nonautologous bone marrow mesenchymal stem/stromal cells (MSCs) are being evaluated as proangiogenic agents for ischemic and vascular disease in adults but not in children. …”
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Protective Effect of Baccharis trimera Extract on Acute Hepatic Injury in a Model of Inflammation Induced by Acetaminophen by Bruno da Cruz Pádua, Joamyr Victor Rossoni Júnior, Cíntia Lopes de Brito Magalhães, Míriam Martins Chaves, Marcelo Eustáquio Silva, Maria Lucia Pedrosa, Gustavo Henrique Bianco de Souza, Geraldo Célio Brandão, Ivanildes Vasconcelos Rodrigues, Wanderson Geraldo Lima, Daniela Caldeira Costa

“…When administered in high doses, APAP is a clinical problem in the US and Europe, often resulting in severe liver injury and potentially acute liver failure. Studies have demonstrated that antioxidants and anti-inflammatory agents effectively protect against the acute hepatotoxicity induced by APAP overdose. …”
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Substituted piperazine conjugated to quinoline-thiosemicarbazide as potent α-glucosidase inhibitors to target hyperglycemia by Mehran Ghasemi, Mohammad Mahdavi, Maryam Dehghan, Mohammadreza Eftekharian, Somayeh Mojtabavi, Mohammad Ali Faramarzi, Aida Iraji, Ahmed Al-Harrasi

“…In this study, a series of thiosemicarbazide-linked quinoline-piperazine derivatives were synthesized and evaluated for their α-glucosidase inhibitory activity, to identify new agents for type 2 diabetes management. Structure-activity relationship (SAR) analysis revealed that the nature and position of substituents on the aryl ring significantly impacted the inhibitory potency. …”
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Demystifying E407 and E407a Additives (Carrageenans) Through Their Gastronomic Alchemy: A Contribution to Increase Consumer Sovereignty by Carla Matos, Manuela M. Moreira, Hélio Loureiro, Lígia Rebelo Gomes

“…This work reviews the physical/chemical properties of carrageenans, which are widely used as thickening and stabilizing agents in a wide range of everyday foods. This critical revision was made through bibliographic searches between January and May 2024 in the PubMed and Web of Science databases. …”
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Enhancing professional development for Third Space roles: reflections on the added value of Learning Circles by Linde Moriau, Réka Matolay, Emma McKenna, Andrea Toarniczky, Judit Gáspár, Márta Frigyik, Catherine Bates

“…We demonstrate that Learning Circles have the potential to create agentic, distributed, and adaptive professional learning spaces, enabling participating staff in reimagining their professional space, so that they feel better prepared to assume the hybrid roles and responsibilities that practices of engagement typically entail. …”
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Endophytic fungi isolated from Vietnamese nut grass (Cyperus rotundus L. Cyperaceae) – A promising solution to mitigate the prime phenomenon of antibiotic resistance by Bac V.G. Nguyen, Linh X.T. Tran, Anh-Tu Ha-Nguyen, Minh-Tri Le, Thanh-Hoa Vo, Gia Phong Vu, Phuoc-Vinh Nguyen

“…., a common Asian medicinal herbal remedy, is gaining increasing attention in the scientific community as a potential source of antimicrobial agents. In this study, endophytic fungi living in this plant were isolated, macro- and micrologically identified, and assessed for their antibacterial properties on both Gram-positive and Gram-negative bacteria. …”
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The Caretaker: Cartografia de Afetos no Estado Demencial // The Caretaker: Cartography of Affections in the Demented State by Ana Rita Queiroz Ferraz, Iuri Cerqueira Moldes Morais

“…“Everywhere at the End of Time” é uma coletânea dividida em seis álbuns musicais, narrativamente denominados de estágios, com aproximadamente seis horas e meia de duração. …”
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Sustainable biopolymer-based spheres for controlled release of nematodes: From development to their effects under seasonal climate variations by Javier Pitti Caballero, Rubén Collantes, Débora R. Antunes, Jahzeel Samaniego, Yabelys Santamaría, Jorge Muñoz, Renato Grillo

“…The formulations were engineered to enable the controlled release of biocontrol agents, optimizing plant growth under varying seasonal climatic conditions (rainy, dry, and transitional seasons). …”
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Improved conversion of carbon dioxide to methane via photohydrogenation using Gd2NiMnO6 with a dendritic fibrous architecture by Ping Yan, Dulong Feng, Qian Wan, Shulong Liu, Seyed Mohsen Sadeghzadeh

“…This work introduces a reusable, magnetically responsive nanocatalyst for the targeted light reduction of CO₂ to CH₄, utilizing eco-friendly methods, mild thermal conditions, ambient pressure, and sustainable dehydrating agents. This approach provides significant economic benefits and compatibility with functional groups, highlighting the potential of combining 3D nanoparticle structures with sustainable chemistry to create highly efficient catalytic systems for CO₂ to CH₄ conversion.…”
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El diseño de proyectos educativos en contextos comunitarios. Un estudio de caso en Celrà (Cataluña, España) by Paula Boned, Elisabet Gubern, Elisenda Quintana, Moisès Esteban-Guitart

“…El objetivo de esta investigación, basada en el diseño, consistió en ilustrar el proceso de creación de un proyecto educativo por parte de un grupo motor formado por distintos agentes sociales, educativos y comunitarios del municipio de Celrà (Catalunya, España). …”
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Hybrid Hydrogel Supplemented with Algal Polysaccharide for Potential Use in Biomedical Applications by Dana Stan, Andreea-Cristina Mirica, Sorin Mocanu, Diana Stan, Iunia Podolean, Natalia Candu, Magdi El Fergani, Laura Mihaela Stefan, Ana-Maria Seciu-Grama, Ludmila Aricov, Oana Brincoveanu, Carmen Moldovan, Lorena-Andreea Bocancia-Mateescu, Simona M. Coman

“…Hydrogels are a viable option for biomedical applications due to their biocompatibility, biodegradability, and ability to incorporate various healing agents while maintaining their biological efficacy. …”
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Retargeting Clostridium difficile Toxin B to Neuronal Cells as a Potential Vehicle for Cytosolic Delivery of Therapeutic Biomolecules to Treat Botulism by Greice Krautz-Peterson, Yongrong Zhang, Kevin Chen, George A. Oyler, Hanping Feng, Charles B. Shoemaker

“…Development of botulism antidotes will require neuronal delivery of agents that inhibit or destroy the BoNT protease. …”
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Safety Evaluation of Multiple Strains of Lactobacillus plantarum and Pediococcus pentosaceus in Wistar Rats Based on the Ames Test and a 28-Day Feeding Study by Cheng-Chih Tsai, Sew-Fen Leu, Quan-Rong Huang, Lan-Chun Chou, Chun-Chih Huang

“…Three lactic acid bacterial strains, Lactobacillus plantarum, HK006, and HK109, and Pediococcus pentosaceus PP31 exhibit probiotic potential as antiallergy agents, both in vitro and in vivo. However, the safety of these new strains requires evaluation when isolated from infant faeces or pickled cabbage. …”
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Novel cis-Pt(II) Complexes with Alkylpyrazole Ligands: Synthesis, Characterization, and Unusual Mode of Anticancer Action by Jana Kasparkova, Hana Kostrhunova, Vojtech Novohradsky, Аlexey A. Logvinov, Viktor V. Temnov, Nataliya E. Borisova, Tatiana A. Podrugina, Lenka Markova, Pavel Starha, Alexey. A. Nazarov, Viktor Brabec

“…One concept of improving anticancer effects of conventional platinum-based antitumor drugs consists of conjugating these compounds with other biologically (antitumor) active agents, acting by a different mechanism. Here, we present synthesis, physicochemical characterization, biological effects, and mechanisms of action of four new analogs of conventional cisplatin, namely, cis-Pt(II) complexes containing either methyl or ethyl pyrazole N-donor ligands and chlorido or iodido ligands. …”
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Entre la planeación urbana, la apropiación del espacio y la participación ciudadana. Los pactos ciudadanos y el Parque Biblioteca España de Santo Domingo Savio by María Eugenia González Vélez, Catalina Carrizosa Isaza

“…El urbanismo social, bandera de estas administraciones, ha promovido procesos de transformación arquitectónica y social en búsqueda de la inclusión de sectores históricamente marginados; que conjuga diversas relaciones de confrontación y genera una integración social que no se aleja de la imagen marginal, sino que genera espacios políticos y de representación donde pese a las transformaciones, la marginalidad de estos lugares persiste como marco histórico e interpretativo que permite hacer “legible” para la alcaldía y para la ciudad este territorio.…”
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Renal Anemia Control in Lithuania: Influence of Local Conditions and Local Guidelines by Edita Ziginskiene, Vytautas Kuzminskis, Kristina Petruliene, Ruta Vaiciuniene, Asta Stankuviene, Inga Arune Bumblyte

“…Erythropoietin stimulating agents had a long haul in Lithuania—we had no epoetin till 1994 and there was no intravenous iron in 2001–2004. …”
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New Potential Weapons for Refractory Scleritis in the Era of Targeted Therapy by Claudia Fabiani, Jurgen Sota, Maite Sainz-de-la-Maza, Laura Pelegrín, Giacomo Emmi, Giuseppe Lopalco, Florenzo Iannone, Lorenzo Vannozzi, Silvana Guerriero, Maria Chiara Gelmi, Donato Rigante, Gian Marco Tosi, José Hernández-Rodríguez, Luca Cantarini

“…This is a retrospective study assessing the efficacy of several biologic agents (rituximab, anakinra, tocilizumab, and abatacept) and the small molecule tofacitinib in the treatment of scleritis through assessment of scleral inflammation and relapses, as well as treatment impact on best-corrected visual acuity (BCVA) and safety profile. …”
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