Targeting HIF-1α to Prevent Renal Ischemia-Reperfusion Injury: Does It Work? by Kapil Sethi, Kenny Rao, Damien Bolton, Oneel Patel, Joseph Ischia

“…While many promising chemical agents have been trialed for the prevention of IRI in small animal studies, all have failed in human trials. …”
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Propiedades psicométricas de un instrumento en construcción para evaluar la inteligencia emocional en alumnos de secundaria y la universidad by Federico Pulido Acosta, Francisco Herrera Clavero

“…Los resultados obtenidos reflejan niveles de fiabili - dad aceptables y las dimensiones teóricas esperadas para ambos cuestionarios, apareciendo intercorrela - ciones positivas entre los totales y las dimensiones que los conforman. …”
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Rede global de produção automotiva: o caso da Stellantis em Goiana (PE) by Cristiano Fonseca Monteiro, Raphael Jonathas da Costa Lima, Lucas do Amaral Afonso

“…Estes casos foram analisados com o propósito de explorar uma dimensão sociológica fundamental no capitalismo contemporâneo, qual seja, o estado das relações de poder entre corporações multinacionais e agentes locais.…”
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Activating PKC-ε induces HIV expression with improved tolerability. by Alivelu M Irrinki, Jasmine Kaur, Bally Randhawa, Ryan McFadden, Chelsea Snyder, Hoa Truong, Daniel Soohoo, Eric Hu, Helen Yu, Bernard P Murray, Bing Lu, Dmytro Kornyeyev, Ishak Darryl Irwan, Lan Nguyen, Yu-San Yang, Jean-Philippe Belzile, Uli Schmitz, Todd C Appleby, Brian Schultz, Jay Lalezari, Steven Deeks, Tomas Cihlar, Jeffrey P Murry

“…Protein kinase C (PKC) isozymes increase HIV transcription and hence are potential latency reversal agents. However, the clinical utility of PKCs for this application is limited due to toxicity, which is poorly understood. …”
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A Review of the Aetiopathogenesis and Clinical and Histopathological Features of Oral Mucosal Melanoma by Liviu Feller, Razia A. G. Khammissa, Johan Lemmer

“…The pathogenesis of oral mucosal melanoma is complex involving multiple interactions between cytogenetic factors including dysregulation of the cKit signalling pathways, cell cycle, apoptosis, and cell-to-cell interactions on the one hand and melanin itself, melanin intermediates, and local microenvironmental agents regulating melanogenesis on the other hand. …”
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A compatibilidade da prática de zero-rating com a previsão de neutralidade de rede by Caio Mario da Silva Pereira Neto, Ronaldo Lemos, Mateus Piva Adami, Felipe Moreira de Carvalho

“…A partir da interpretação desenvolvida em conformidade com o preceito constitucional da livre-iniciativa e também com a legislação setorial de telecomunicações - à qual os provedores de conexão à internet, enquanto agentes privados, estão sujeitos -, procura-se explicar a legalidade da prática de ofertas zero-rating, que fazem parte do âmbito de liberdade negocial dos entes privados. …”
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INTERPASSIVITY AS A SUBJECTIVE EFFECT OF MODERN MEDIA-CULTURE: TO THE STATEMENT OF PROBLEM by Olena V. Khodus

“…It is proved that in the modern media culture, the subject is not so much a passive spectator, observer, collector information and events to represent relevant interested agents. He also actively reproduces itself in a form of "perceived privacy", which allows special mode of the experiences of private emotions "alone with everybody." …”
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Release of P-TEFb from the Super Elongation Complex promotes HIV-1 latency reversal. by William J Cisneros, Shimaa H A Soliman, Miriam Walter, Lacy M Simons, Daphne Cornish, Simone De Fabritiis, Ariel W Halle, Eun-Young Kim, Steven M Wolinsky, Ramon Lorenzo-Redondo, Ali Shilatifard, Judd F Hultquist

“…KL-2 acts synergistically with other latency reversing agents (LRAs) to reactivate viral transcription in several cell line models of latency in a manner that is, at least in part, dependent on the viral Tat protein. …”
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Respiratory diseases in young cattle by T. S. Ermilova, M. A. Samburova, O. V. Kasharnaya, E. A. O. Salimzade

“…However, out of the major calf diseases, particular mention should be made of pneumonia, which is most often caused by viruses. In this case agents can induce bacterial infection which aggravates and complicates the course of viral diseases. …”
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The Effects of Punica granatum Flower Extract on Skin Injuries Induced by Burn in Rats by Ebrahim Nasiri, Seyed Jalal Hosseinimehr, Jafar Akbari, Mohammad Azadbakht, Soheil Azizi

“…The wounds completely healed on day 25 of the treatment in rats treated with creams containing P. granatum flower extract compared with those in rats treated with the other agents. Conclusion. These results indicated that P. granatum flower extract promoted wound healing in rats and could be used for managing burn injuries.…”
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Consensus guidelines for the management of treatment-naïve chronic lymphocytic leukaemia in Singapore (2024) by Yeow Tee Goh, Yvonne Loh, Esther Chan, Yuh Shan Lee, Venkata Sreekanth Sampath, Daryl Tan, Shin Yeu Ong, Chandramouli Nagarajan

“…Due to the superior efficacy of targeted agents (Bruton's tyrosine kinase inhibitors [BTKis] and B-cell lymphoma 2 inhibitors [BCL2is]), sthese are favoured over standard chemotherapy or chemotherapy-immunotherapy, especially for patients with del(17p) or TP53 mutation, and less fit patients. …”
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Inflammation and Inflammasomes: Pros and Cons in Tumorigenesis by Liliana R. Balahura, Aida Selaru, Sorina Dinescu, Marieta Costache

“…So far, many efforts have been made in order to extend the knowledge of inflammasome implications and how its components could be targeted as therapeutic agents. Additionally, microRNAs (miRNAs), evolutionary conserved noncoding molecules, have emerged as pivotal players during numerous biological events by regulating gene and protein expression. …”
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The Effect of Prucalopride on Small Bowel Transit Time in Hospitalized Patients Undergoing Capsule Endoscopy by Majid Alsahafi, Paula Cramer, Nazira Chatur, Fergal Donnellan

“…VCE studies were excluded if the capsule was retained or endoscopically placed, if other prokinetic agents were given, in cases with technical failure, or if patients had prior gastric or small bowel resection. …”
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Comprehensive review of preclinical evaluation strategies for COVID-19 vaccine candidates: assessing immunogenicity, toxicology, and safety profiles by Delaram Doroud, Mojtaba Daneshi, Fatemeh Kazemi-Lomedash, Zohre Eftekhari

“… Following the worldwide spread of Severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2), there is a vital requirement for safe and effective vaccines against Coronavirus disease 2019 (COVID-19). …”
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Anticancer potential of coumarins from the Ferulago genus by Mansour Mofasseri, Elham Eini, Saber Mofasseri, Bahram Hanifehpour, Fatemeh Zanbili, Ahmad Poursattar Marjani

“…Cancer treatment needs better therapeutic agents with fewer side effects compared to the present anticancer and antitumor drugs. …”
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A Novel Modeling Technique for the Forecasting of Multiple-Asset Trading Volumes: Innovative Initial-Value-Problem Differential Equation Algorithms for Reinforcement Machine Learni... by Mazin A. M. Al Janabi

“…In this paper, we do not propose a definitive one either, but we attempt to derive novel mathematical algorithms for the dynamic modeling of trading volumes during the closeout period from the perspective of multiple-asset portfolio(s), as well as for financial entities with different subsidiary firms and multiple agents. The robust modeling techniques are based on the application of initial-value-problem differential equations technique for portfolio selection and risk management purposes. …”
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Pobreza subnacional en México y el Fondo de Aportaciones para Infraestructura Social by Cesar Gurrola Ríos, Paola Vázquez Molina

“…Los resultados del estudio son relevantes para agentes económicos interesados en mejorar las condiciones de vida de la población mexicana a través del diseño, implementación y monitoreo de políticas públicas orientadas a combatir la pobreza en México.…”
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Diseño de una red de participación de actores para la gestión de los sistemas de financiamiento by Laura Angelina Obando Uzcátegui, Juan Carlos Delgado Barrios

“…Una de las maneras de impulsar el desarrollo económico local en las regiones es mediante la integración de esfuerzos de los agentes locales en redes de participación, con la intención de gestionar mancomunadamente intereses en común. …”
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Comparative metabolic study of planktonic and sessile cells in Salmonella Enteritidis ATCC 13076: Elucidating metabolic pathways driving biofilm formation. by Yuliany Guillín, Claudia Ortiz, William Hidalgo

“…Microorganisms tend to accumulate on surfaces, forming aggregates such as biofilms, which grant them resistance to various environmental stressors and antimicrobial agents. This ability has hindered the effective treatment of diseases caused by pathogenic microorganisms, including Salmonella, which is responsible for a significant number of deaths worldwide. …”
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Primera evidencia de Chlamydia psittaci en huron sable (Mustella putorios furo) en Venezuela by C. Rodríguez-Leo, D. Camacho, V. Hernández-Aguilera, M. Viettri, C. Flores, H. Henríquez, M. González

“…Se desconoce el total de reservorios de Cp, por ello la notificación de los aislados permite el entendimiento, distribución y diversidad de agentes clamidiales en fauna silvestre y en cautiverio.…”
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