Cooccurrence of Metastatic Papillary Thyroid Carcinoma and Salmonella Induced Neck Abscess in a Cervical Lymph Node by Jae-Myung Kim, Ju-Yeon Kim, Eun Jung Jung, Eun Jin Song, Dong Chul Kim, Chi-Young Jeong, Young-Tae Ju, Young-Joon Lee, Soon-Chan Hong, Sang-Kyung Choi, Woo-Song Ha

“…The patient presented with painful swelling in her left lateral neck region for 15 days, and neck ultrasonography and computed tomography showed a cystic mass along left levels II–IV. …”
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Dimethyl fumarate promotes the degradation of HNF1B and suppresses the progression of clear cell renal cell carcinoma by Yue Dai, Hongchen Li, Shiyin Fan, Kai Wang, Ziyi Cui, Xinyu Zhao, Xue Sun, Mingen Lin, Jiaxi Li, Yi Gao, Ziyin Tian, Hui Yang, Bingbing Zha, Lei Lv, Yanping Xu

“…Therefore, there is an urgent need to discover therapeutic agents for ccRCC treatment. Here, we demonstrate that dimethyl fumarate (DMF), an approved medication for multiple sclerosis [1] and psoriasis, can inhibit the proliferation of ccRCC cells. …”
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Nafion®-Containing Solid Lipid Nanoparticles as a Tool for Anticancer Pt Delivery: Preliminary Studies by Maddalena Sguizzato, Elisabetta Esposito, Marcus Drechsler, Eleonora Gallerani, Riccardo Gavioli, Paolo Mariani, Federica Carducci, Rita Cortesi, Paola Bergamini

“…By 13P-NMR measures, it is here proved that the strongly acidic sulfonic groups of Nafion-containing nanoparticles (NAF) can act as protonating agents for PTA. The protonation occurs selectively at nitrogen; hence protonated PTA maintains its ability to coordinate platinum via its phosphorus atom.…”
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Assessment of Acute and Chronic Pharmacological Effects on Energy Expenditure and Macronutrient Oxidation in Humans: Responses to Ephedrine by Antonella Napolitano, Peter R. Murgatroyd, Nick Finer, Elizabeth K. Hussey, Robert Dobbins, Steve O'Rahilly, Derek J. R. Nunez

“…We demonstrate that overnight or 23-hour, 2% energy expenditure (EE) and 5% fat (FO) or CHO oxidation effects are detectable both acutely and over 14 days. Compared to placebo, ephedrine increased EE and FO rates overnight (EE 63 kJ day 2, EE 105 kJ, FO 190 kJ, day 14), but not over 23 h. …”
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O resgate das teorias do imperialismo para a análise do neoliberalismo: um debate* by Vinícius Vieira Pereira

“…Suscitamos o pensamento de Marx e Engels acerca dos meios da produção espiritual, n’A Ideologia Alemã, para nos auxiliar nesse debate.…”
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Mitochondrial-targeted therapies in traumatic brain injury: From bench to bedside by Sidra Tabassum, Silin Wu, Chang-Hun Lee, Bosco Seong Kyu Yang, Aaron M. Gusdon, Huimahn A. Choi, Xuefang S. Ren

“…We also evaluate various preclinical studies exploring pharmacological agents, gene therapy, and novel drug delivery systems designed to protect and restore mitochondrial function. …”
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Streptomyces-derived nano-doxorubicin: Clinical status and patents granted by Kaur Prabhjot, Bhandari Divya Dhawal, Chopra Hitesh

“…This review attempts to compile the existing literature on the clinical status of DOX highlight the need for the development of nanoparticles (NPs) that may serve as drug delivery agents, imaging probes and other multifunctional particulates. …”
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Cellular Mechanisms of Multiple Myeloma Bone Disease by Angela Oranger, Claudia Carbone, Maddalena Izzo, Maria Grano

“…Therefore, the understanding of MM pathogenesis could be useful to the discovery of novel agents that will be able to both restore bone remodelling and reduce tumor burden.…”
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<i>Klebsiella pneumoniae</i> Phage M198 and Its Therapeutic Potential by Lika Leshkasheli, Ia Kusradze, Darejan Bolkvadze, Lia Askilashvili, Maria Chichashvili, Giorgi Tsertsvadze, Elisabed Zaldastanishvili

“…Non-antibiotic antibacterial agents are in high demand for many Gram-negative bacterial pathogens, including <i>Klebsiella pneumoniae</i>. …”
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Acidic Microenvironment Enhances Cisplatin Resistance in Bladder Cancer via Bcl-2 and XIAP by Kaede Hiruma, Vladimir Bilim, Akira Kazama, Yuko Shirono, Masaki Murata, Yoshihiko Tomita

“…Cisplatin (CDDP) remains a key drug for patients with advanced bladder cancer (BC), despite the emergence of new therapeutic agents; thus, the identification of factors contributing to CDDP treatment resistance is crucial. …”
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Endophytic Fungi of <i>Calea pinnatifida</i> (Asteraceae): Dereplication of Crude Extracts, Antimicrobial Properties, and Identification of New Tetronic Acid Derivative Produced by... by Bianca Barna, Lhaís Araújo Caldas, Jackson Monteiro, Augusto Leonardo dos Santos, Renata Castiglioni Pascon, Marcelo Afonso Vallim, Marcelo José Pena Ferreira, Sarah Santos Gonçalves, Glaucia Queiroz dos Santos, Anderson Messias Rodrigues, Jamile Ambrósio de Carvalho, Suzan Pantaroto de Vasconcellos, Patricia Sartorelli

“…This study highlights the potential of endophytic fungi as a valuable source of novel antimicrobial agents.…”
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Antibacterial and Pharmacological Evaluation of Fluoroquinolones: A Chemoinformatics Approach by Damini Sood, Neeraj Kumar, Aarushi Singh, Meena Kishore Sakharkar, Vartika Tomar, Ramesh Chandra

“…Fluoroquinolone (FQ) antibiotics are an important class of synthetic antibacterial agents. These are the most extensively used drugs for treating bacterial infections in the field of both human and veterinary medicine. …”
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Partial Purification of Integral Membrane Antigenic Proteins from Trypanosoma evansi That Display Immunological Cross-Reactivity with Trypanosoma vivax by Norma P. Velásquez, Rocío E. Camargo, Graciela L. Uzcanga, José Bubis

“…Trypanosoma evansi and Trypanosoma vivax, which are the major causative agents of animal trypanosomosis in Venezuela, have shown a very high immunological cross-reactivity. …”
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Density functional theory and molecular dynamics simulation-based bioprospection of Agathosma betulina essential oil metabolites against protein tyrosine phosphatase 1B for interve... by Oluwaseye Adedirin, Rukayat A. Abdulsalam, Khadeejah O. Nasir-Naeem, Ayenitaju A. Oke, Akolade O. Jubril, Saheed Sabiu

“…While conventional antihyperglycemic medications like biguanides, sulfonylureas, and other agents are commonly used, their long-term use can have side effects, prompting research into natural alternatives. …”
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Diagnosis of Fanconi Anemia: Mutation Analysis by Multiplex Ligation-Dependent Probe Amplification and PCR-Based Sanger Sequencing by Johan J. P. Gille, Karijn Floor, Lianne Kerkhoven, Najim Ameziane, Hans Joenje, Johan P. de Winter

“…A clinical diagnosis of FA needs to be confirmed by testing cells for sensitivity to cross-linking agents in a chromosomal breakage test. As a second step, DNA testing can be employed to elucidate the genetic subtype of the patient and to identify the familial mutations. …”
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Noninvasive in vivo imaging of macrophages: understanding tumor microenvironments and delivery of therapeutics by Prakash Gangadaran, Akanksha Onkar, Ramya Lakshmi Rajendran, Anshika Goenka, Ji Min Oh, Fatima Khan, ArulJothi Kandasamy Nagarajan, Sathish Muthu, Anand Krishnan, Chae Moon Hong, Byeong-Cheol Ahn

“…The integration of multimodal imaging approaches and the continued development of novel contrast agents hold promise for overcoming current limitations and expanding the applications of macrophage imaging. …”
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Synthesis and Evaluation of In Vitro Antibacterial and Antitumor Activities of Novel N,N-Disubstituted Schiff Bases by Heng Luo, Yu-fen Xia, Bao-fei Sun, Li-rong Huang, Xing-hui Wang, Hua-yong Lou, Xu-hui Zhu, Wei-dong Pan, Xiao-dong Zhang

“…Overall, our novel N,N-disubstituted Schiff bases possess unique antibacterial or antitumor activities that exhibit the potent application prospect in prophylactic or therapeutic interventions, providing new insights for developing new antibacterial and anticancer chemical agents.…”
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Uncovering Psychedelics: From Neural Circuits to Therapeutic Applications by Alice Melani, Marco Bonaso, Letizia Biso, Benedetta Zucchini, Ciro Conversano, Marco Scarselli

“…Psychedelics, historically celebrated for their cultural and spiritual significance, have emerged as potential breakthrough therapeutic agents due to their profound effects on consciousness, emotional processing, mood, and neural plasticity. …”
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Dual mechanisms of G3 against Vibrio parahaemolyticus in shrimp aquaculture by Cuixia Chen, Yangyang Ge, Qilong Gu, Tianling Wang, Yanyan Yang, Jinpeng Hu, Kang Gao, Xing Zhou, Hui Li

“…The unfavorable side effects and emergence of superbugs in traditional antibiotic treatment makes development of excellent antibacterial agents especially urgent. Antimicrobial peptides (AMPs), which usually have high antibacterial activity and low potential to induce bacterial resistance, are considered as the promising alternatives to conventional antibiotics. …”
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Unveiling the rhizosphere microbiome of Dendrobium: mechanisms, microbial interactions, and implications for sustainable agriculture by Surendra Sarsaiya, Surendra Sarsaiya, Archana Jain, Ranjan Singh, Qihai Gong, Qin Wu, Jishuang Chen, Jingshan Shi, Jingshan Shi

“…., Glomus spp.), and biocontrol agents (Trichoderma spp.), and discusses their roles in nutrient cycling, disease suppression, and plant growth promotion. …”
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