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30101
Dynamics of particulate emissions in the presence of autonomous vehicles
Published 2025-01-01“…Around one third of CO2{{\rm{CO}}}_{2} emissions in the atmosphere are linked to vehicular traffic. Pollutant agents have an impact on the environment, in particular, the increased presence of particulate matter (PM) creates negative effects on human health. …”
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30102
Development of antibacterial magnetic clay-based nanocomposites for water treatment
Published 2024-03-01“…In addition, the agar disk-diffusion method revealed that antimicrobial agents were not released from clays, which is a relevant fact in the water treatment process.…”
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30103
Advancements and Challenges in Immune Protection Strategies for Islet Transplantation
Published 2025-01-01“…However, the limited availability of human cadaveric islet donors and the need for ongoing administration of immunosuppressive agents post‐transplantation hinder the widespread use of this treatment. …”
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30104
Effects of Microtubule Stabilization by Epothilone B Depend on the Type and Age of Neurons
Published 2016-01-01“…Several studies have demonstrated the therapeutic potential of applying microtubule- (MT-) stabilizing agents (MSAs) that cross the blood-brain barrier to promote axon regeneration and prevent axonal dystrophy in rodent models of spinal cord injury and neurodegenerative diseases. …”
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30105
Genotoxic Potential and Physicochemical Parameters of Sinos River, Southern Brazil
Published 2013-01-01“…Thus, the physicochemical parameters indicated that the water quality of the upper course complies with the limits set by the national guidelines, and the ecotoxicological assessment, however, indicated the presence of genotoxic agents. The present study highlights the importance of combining water physicochemical analysis and bioassays to river monitoring.…”
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30106
Gd3+-Doped Magnetic Nanoparticles for Biomedical Applications
Published 2018-01-01“…Magnetic nanoparticles (MNPs) made of iron oxides with cubic symmetry (Fe3O4, γ-Fe2O3) are demanded objects for multipurpose in biomedical applications as contrast agents for magnetic resonance imaging, magnetically driven carriers for drug delivery, and heaters in hyperthermia cancer treatment. …”
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30107
Multitargeted Effects of Vitexin and Isovitexin on Diabetes Mellitus and Its Complications
Published 2021-01-01“…Till date, there is no known antidote to cure diabetes mellitus despite the discovery and development of diverse pharmacotherapeutic agents many years ago. Technological advancement in natural product chemistry has led to the isolation of analogs of vitexin and isovitexin found in diverse bioresources. …”
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30108
Therapy of Osteoporosis in Men with Teriparatide
Published 2011-01-01“…Attempts to show further beneficial effects of teriparatide in combination with antiresorptive agents have not been demonstrated yet to be superior to monotherapy with teriparatide alone. …”
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30109
Deficiency of Interleukin-1 Receptor Antagonist: A Case with Late Onset Severe Inflammatory Arthritis, Nail Psoriasis with Onychomycosis and Well Responsive to Adalimumab Therapy
Published 2019-01-01“…The DIRA disease can lead to death from multiple organ failures and if recognized early, the treatment with replacement of the deficient protein with biologic agents induces rapid and complete remission. Therefore, clinical symptoms should be learned exactly by the pediatricians, pediatric rheumatologists, and immunologists; and molecular analysis targeting this defect must be performed as early as possible.…”
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30110
Human microbiomes in cancer development and therapy
Published 2023-04-01“…It is largely unknown how microbial agents cause cancer or how cancer progresses. We expect this review may open new perspectives on possible therapeutic approaches of patients with cancer.…”
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30111
Exploring Antibacterial Properties of Marine Sponge-Derived Natural Compounds: A Systematic Review
Published 2025-01-01“…The structural features of the active compounds selected in this review may provide a foundational framework for developing new, highly bioactive antimicrobial agents.…”
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30112
Functional and Antimicrobial Properties of Propolis from Different Areas of Romania
Published 2025-01-01“…This substance plays a crucial role in the hive’s defence against a range of pathogenic agents, maintaining a consistent internal temperature and aseptic environment for the bee colony. …”
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30113
Treating Antibiotic Resistance Genes in Proteus Spp. were Isolated from Renal Stone Patients by Crataegus rhipidophylla and Adiantum capillus
Published 2018-07-01“…The antibiotic susceptibility test for all isolates were conducted to nine antimicrobial agents including (Ciprofloxacin (Cip), Tetracycline(TE), Neomycin (N), Gentamicin (CN), Erythromycin (E), Nitrofurantoin (F), Naldixic acid (NA), Imipenem (IPM), Amoxicillin (AX). …”
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30114
Enhanced antitumor efficacy through sustained release of 5-fluorouracil from poly(trimethylene carbonate) membranes
Published 2025-01-01“…IntroductionCancer remains one of the deadliest diseases worldwide. 5-Fluorouracil (5-FU) is one of the most commonly used chemotherapeutic agents in clinical practice today, but its effectiveness is often hampered by rapid drug metabolism and systemic toxicity. …”
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30115
Fungal Exposure and Low Levels of IL-10 in Patients with Sarcoidosis
Published 2014-01-01“…The low serum IL-10 values at high fungal exposure suggest that fungal cell wall agents play a role in granuloma formation in sarcoidosis by inhibiting the secretion of the anti-inflammatory cytokine IL-10.…”
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30116
An in-depth study of indolone derivatives as potential lung cancer treatment
Published 2025-01-01“…The ADMET analysis revealed that these compounds exhibited favourable drug-like properties, meeting nearly all the key pharmacological criteria required for potential therapeutic agents. Molecular docking studies of the most active compounds revealed strong interactions with critical amino acid residues in the PDK1 receptor’s binding site, underscoring their potential as effective PDK1 inhibitors. …”
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30117
Recent advances in pancreatic α-cell transdifferentiation for diabetes therapy
Published 2025-01-01“…As the global prevalence of diabetes mellitus rises, traditional treatments like insulin therapy and oral hypoglycemic agents often fail to achieve optimal glycemic control, leading to severe complications. …”
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30118
G alleria mellonella in vitro model for chromoblastomycosis shows large differences in virulence between isolates
Published 2024-03-01“…Cladophialophora carrionii (C. carrionii) is one of the agents. However, the pathogenesis of C. carrionii is not fully investigated yet. …”
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30119
β-Glucan-modified nanoparticles with different particle sizes exhibit different lymphatic targeting efficiencies and adjuvant effects
Published 2024-12-01“…The results also indicate that β-glucan-modified MSN, with a particle size of ∼100 nm, has a great potential as a vaccine delivery vehicle and immune adjuvant and offers a novel approach for the delivery of multiple therapeutic agents that target other lymph-mediated diseases.…”
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30120
Fatal Epstein-Barr Virus Reactivation in an Acquired Aplastic Anemia Patient Treated with Rabbit Antithymocyte Globulin and Cyclosporine A
Published 2015-01-01“…One month after the start of ATG, persistent fever which was not responsive to antibiotics or antifungal agents developed and atypical lymphocytes emerged in peripheral blood. …”
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