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30041
La educación inclusiva hoy. Reconocer al otro y crear comunidad a través del diálogo y la participación
Published 2011-01-01“…Así, reconociendo la importancia que para los estudiantes y sus profesores tiene sentirse vinculados a los proyectos y actividades que nutren la dinámica escolar, las conclusiones de la investigación nos permiten enriquecer y plantear nuevos retos a las prácticas docentes y de investigación inclusivas, unos hallazgos que plantean no sólo dilemas sobre cómo mejorar los procesos educativos reconociendo a los estudiantes como agentes de cambio, sino también el papel de la investigación en el acompañamiento de estas necesarias transformaciones.…”
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30042
Comparative Studies of Combined Influence of Variables on the Esterification Degree of Pectin Extracted by Sulfuric Acid and Citric Acid
Published 2019-01-01“…The influence of extraction variables on degree of esterification (DE) of pectin was studied due to the significant effects of DE on the properties of the pectin-based functional biomaterials. The extracting agents (sulfuric acid and citric acid), pH value of extraction solution, extraction time, and temperature were selected to study the hydrolysis reaction of carboxylic acid ester by response surface methodology (RSM). …”
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30043
Exploring effector protein dynamics and natural fungicidal potential in rice blast pathogen Magnaporthe oryzae.
Published 2025-01-01“…Molecular dynamics simulations further confirmed that these compounds form stable, strong interactions with the target proteins, validating their potential as therapeutic agents. Additionally, the compounds were evaluated based on Lipinski's rule of five and toxicity predictions, indicating their suitability for agricultural use. …”
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30044
Efficacy and safety of conventional synthetic, biologic, and targeted synthetic disease-modifying antirheumatic drugs in rheumatoid arthritis-interstitial lung disease: A narrative...
Published 2021-01-01“…The evidence has been controversial with many agents implicated both in the context of predisposing or worsening the risk of ILD and at the same time as potentially beneficial treatments in delaying the onset or progression of ILD. …”
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30045
ILORIN EMIRATE TYPE OF ADMINISTRATION IN ISINLAND 1836-1947: A HISTORICAL ANALYSIS
Published 2022-05-01“…This Pre[1]Ilorin Emirate type of administration of Isinland was distorted both in organization and direction with the arrival of Ilorin Emirate political agents into Isinland as heads of administration.The objective of this study is to criticallyinvestigate Ilorin Emirate type of administration in Isinland 1836-1947 as typical example of Ilorin Emirate administration in the non-metropolitan center of the Emirate.The research methodology explored was historical.The primary sources comprised oral interview across prominent individuals of Isinland and at Ajia Opelle’s compound of Ilorin. …”
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30046
Las tribulaciones del sargento mayor. Conflictos de jurisdicción y relaciones fronterizas en el sur de Santiago del Estero a fines del siglo XVIII
Published 2022-01-01“…Acusado de robar ganado a través de sus protegidos y de abusar de su autoridad por sus fueros, el proceso contra Espínola ilumina las tramas de parentesco, obediencia y dependencia, así como los conflictos de jurisdicción al momento de la creación de las intendencias del Tucumán y de la expansión de los agentes judiciales en la campaña. La segunda se refiere al Espínola comandante de fronteras en las cercanías del fuerte de Abipones y a su papel articulador con los grupos guaycurúes.…”
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30047
Maxillary osteonecrosis linked to Pembrolizumab therapy: a case report
Published 2024-01-01“…Introduction: Osteonecrosis of the jaw is a serious condition often associated with the use of bone-modifying agents or antiangiogenics. Recent evidence suggests that immune checkpoint inhibitors, including Pembrolizumab, might also contribute to osteonecrosis of the jaw. …”
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30048
Understanding Metrics for Communicating the Economic Importance of Florida’s Fisheries Part II: Quantifying Market Activity
Published 2025-02-01“…This information should help readers, especially management agencies and extension agents, as well as the interested public, better understand the metrics associated with quantifying market activity. …”
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30049
Educación Mediática y su Didáctica. Una Propuesta para la Formación del Profesorado en TIC y Medios
Published 2018-01-01“….- Medios y entornos digitales como agentes de educación informal; 3.- Integración curricular de los medios y tecnologías digitales como recursos didácticos; 4.- Integración curricular de TIC y medios como objeto de estudio. …”
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30050
PPAR-γ Agonists and Their Effects on IGF-I Receptor Signaling: Implications for Cancer
Published 2009-01-01“…Synthetic PPAR-γ agonists, such as thiazolidinediones (TZDs), are drugs universally used as antidiabetic agents in patients with type 2 diabetes. In addition of acting as insulin sensitizers, PPAR-γ agonists mediate in vitro and in vivo pleiotropic anticancer effects. …”
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30051
Liver Protective Effect of Fenofibrate in NASH/NAFLD Animal Models
Published 2022-01-01“…To better elucidate the pathophysiological processes underlying NAFLD, as well as to test therapeutic agents/interventions, experimental animal models have been extensively used. …”
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30052
Economistas e educação no Banco Mundial: primórdios de uma relação duradoura no Brasil
Published 2025-01-01“…O artigo destaca que, desde cedo, o BM possuía interlocutores privilegiados no Brasil, agentes que, junto dele, disseminam ideias e um modo de olhar o setor educacional brasileiro (e latino-americano) a partir de uma concepção econômica da educação. …”
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30053
SOFT POWER: THE CONCEPT AND APPROACHES
Published 2017-11-01“…It is emphasized that non-state actors can be agents of states’ soft power. There are also a number of other features of soft power that must be considered. …”
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30054
Conventional-Microwave Mediated Synthesis and In Vitro Antimicrobial Activity of Novel Carbazole-Efflux Pump Inhibitor Hybrid Antibacterials
Published 2017-01-01“…Work presented herein is the first report of two dual-action hybrids synthesized by covalent linkage of carbazole based novel antibacterial compounds with efflux pump inhibitors, that is, indole acetic acid/gallic acid. In this paper, novel antibacterial compounds 2 and 3 were prepared first and then these were covalently linked with efflux pump inhibitors, that is, indole acetic acid/gallic acid leading to the successful formation of two dual-action hybrids 4 and 5. …”
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30055
PSICOLOGIA E MARXISMO: A PRODUÇÃO CIENTÍFICA PUBLICADA NO BRASIL NO SÉCULO XXI
Published 2025-02-01“…Considera-se indispensável que a aproximação com o referencial suscite reflexões para a Psicologia, para questionar a individualização e a psicologização de fenômenos estruturais e reforçar a percepção de seu papel como classe trabalhadora e agente de mudança.…”
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30056
Unleashing the Power of Artificial Intelligence-Driven Drug Discovery in Streptomyces
Published 2024-11-01“…AI-driven drug discovery in Streptomyces sp. represents a paradigm shift in the future quest for novel pharmaceutical agents. Various ML models have been developed and applied in different practical applications. …”
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30057
Alcance y efectos de la nulidad en los contratos conexos en el derecho privado colombiano
Published 2019-01-01“…Se concluye que la nulidad que afecta a un contrato ligado a una red contractual, solo puede extender su efecto en la medida que afecte la causa de la vinculación. Este escrito es el producto de una investigación cualitativa con un enfoque dogmático, de técnica documental especializada.…”
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30058
Effect of Glycoconjugation on Cytotoxicity and Selectivity of 8-Aminoquinoline Derivatives Compared to 8-Hydroxyquinoline
Published 2025-01-01“…Numerous emerging chemotherapeutic agents incorporate <i>N</i>-heterocyclic fragments in their structures, with the quinoline skeleton being particularly significant. …”
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30059
Pathogenic role of lipids in non-alcoholic fatty liver disease
Published 2012-02-01“…Unsaturated fatty acids, essential phospholipids, antioxidants, silymarinum, hypolipidemic agents, glitazones can have protective action. Potential of medical application of caspase inhibitors, cathepsine B, JNKkinase and «chemical chaperones» is under investigation.Conclusion. …”
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30060
Advancements in Nanomedicine for the Diagnosis and Treatment of Kidney Stones
Published 2025-02-01“…Furthermore, contrast agents developed from these materials can improve the signal-to-noise ratio and enhance image clarity. …”
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