Reduced contribution of sulfur to the mass extinction associated with the Chicxulub impact event by Katerina Rodiouchkina, Steven Goderis, Cem Berk Senel, Pim Kaskes, Özgür Karatekin, Michael Ernst Böttcher, Ilia Rodushkin, Johan Vellekoop, Philippe Claeys, Frank Vanhaecke

“…Short-term cooling due to massive release of climate-active agents is hypothesized to have been crucial, with S-bearing gases originating from the target rock vaporization considered an important driving force. …”
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Targeted therapeutic strategies for Nectin-4 in breast cancer: Recent advances and future prospects by Yufei Wang, Guangliang Li, Hanying Wang, Quan Qi, Xian Wang, Haiqi Lu

“…In conclusion, this review aims to provide an overview of the latest advances in understanding the role of Nectin-4 in breast cancer and discuss the future development prospects of Nectin-4 targeted agents.…”
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Drug Screening of Flavonoids as Potential VEGF Inhibitors Through Computational Docking and Cell Models by Shengying Lin, Roy Wai-Lun Tang, Yutong Ye, Chenxi Xia, Jiahui Wu, Ran Duan, Ka-Wing Leung, Tina Ting-Xia Dong, Karl Wah-Keung Tsim

“…The investigation evidently suggested that the three flavonoids above could be considered potential anti-VEGF agents for the following drug development against VEGF-mediated diseases.…”
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Hypoxia-Inducible Factor-1 as a Therapeutic Target in Endometrial Cancer Management by Laura M. S. Seeber, Ronald P. Zweemer, René H. M. Verheijen, Paul J. van Diest

“…Preliminary data shows encouraging results for these agents. Further work is needed to identify selective HIF-1 inhibitors and to translate these into clinical trials.…”
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Eurotium Cristatum Postfermentation of Fireweed and Apple Tree Leaf Herbal Teas by Tatiana A. Efimenko, Elena F. Shanenko, Tatiana G. Mukhamedzhanova, Olga V. Efremenkova, Yuriy A. Nikolayev, Elena N. Bilanenko, Marina V. Gernet, Artem G. Grishin, Ivan N. Serykh, Sergey V. Shevelev, Byazilya F. Vasilyeva, Svetlana N. Filippova, Galina I. El-Registan

“…Fungi Eurotium spp. are the main biological agents that ferment the leaves of the Camellia sinensis tea bush to form a popular food product, postfermented tea. …”
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Spontaneous and environment induced genomic alterations in yeast model by Ke-Jing Li, Lei Qi, Ying-Xuan Zhu, Min He, Qian Xiang, Dao-Qiong Zheng

“…In this review, we highlight the application of genetic screening systems to assess the mutagenic effects of physical and chemical agents efficiently. Additionally, we discuss the utilization of high-throughput sequencing technologies to uncover comprehensive genomic alterations and rare genetic events. …”
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Integrated Simulation Environment for Unmanned Autonomous Systems—Towards a Conceptual Framework by M. G. Perhinschi, M. R. Napolitano, S. Tamayo

“…The generality and completeness of the simulation environment is ensured by including all operational domains, types of agents, external systems, missions, and interactions between components. …”
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Unlocking nature’s pharmacy: an in-depth exploration of phytochemicals as potential sources of anti-cancer and anti-inflammatory molecules by Shifana C. Sadiq, Maria Pellissery Joy, Sreekumar U. Aiswarya, Abhishek Ajmani, Chenicheri K. Keerthana, Tennyson P. Rayginia, Noah Isakov, Ruby John Anto

“…By exploring the promising potential of phytochemical-based remedies for cancer prevention, treatment, and inflammatory conditions and emphasizing their diverse roles in modulating critical regulatory mechanisms, this review addresses the current research landscape, challenges, and future directions in utilizing phytochemicals as effective agents against cancer and inflammation.…”
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Synthesis of Novel Thiazolyl Hydrazine Derivatives and Their Antifungal Activity by Jianjun Zhu, Yazhen Chen, Fen Su, Peiyi Wang

“…Given the excellent bioactivity of designed compounds, this kind of thiazolyl hydrazine framework can provide a suitable point for exploring highly efficient antifungal agents.…”
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Practical Recommendation of the Scientific Сommunity for Human Microbiome Research (CHMR) and the Russian Gastroenterological Association (RGA) on Small Intestinal Bacterial Overgr... by V. T. Ivashkin, I. V. Maev, D. I. Abdulganieva, O. P. Alekseeva, S. A. Alekseenko, O. Yu. Zolnikova, N. V. Korochanskaya, O. S. Medvedev, E. A. Poluektova, V. I. Simanenkov, A. S. Trukhmanov, I. B. Khlynov, V. V. Tsukanov, O. S. Shifrin, K. V. Ivashkin, T. L. Lapina, R. V. Maslennikov, M. V. Fadeeva, A. I. Ulyanin

“…SIBO therapy involves prescription of antibacterial agents, the most studied of which is the non-absorbable antibiotic rifaximin-α.…”
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La higiene de manos una estrategia antigua, eficaz, y sencilla para prevenir infecciones by Mario Chopin Doroteo, Elizabeth Ortega Soto, Dra

“…La higiene de manos es una medida simple y efectiva para disminuir la tasa de transmisión de agentes infecciosos como bacterias y virus. Esta práctica fue adoptada a partir de observaciones e hipótesis sobre la relación entre la transmisión de enfermedades y las manos sucias. …”
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Animal-derived therapeutic alternatives for candidiasis treatment by Manuela Gómez-Gaviria, Joaquín O. Chávez-Santiago, José A. Martínez-Álvarez, Héctor M. Mora-Montes

“…Recently, an increase in the isolation frequency of species different from Candida albicans has been observed, and some of them are characterized by the ability to develop resistance to antifungal drugs, which could be related to the misuse of these agents and biological attributes that allow drug resistance. …”
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SOCIAL NETS AS A NEW FACTOR OF SYSTEM SECURITY IN RUSSIA IN THE 21ST CENTURY by S. A. Kravchenko, A. I. Podberezkin

“…In the context of growing pragmatism and globalization of activities of agents of Western civilization the networks take on the quality of the new and highly effective weapon intended to destroy and destroy high-priority policy objectives. …”
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The Caries Phenomenon: A Timeline from Witchcraft and Superstition to Opinions of the 1500s to Today's Science by John D. Ruby, Charles F. Cox, Naotake Akimoto, Nobuko Meada, Yasuko Momoi

“…European writers of the 1600s to 1700s held views that general health, mechanical injuries, trauma, and sudden temperature changes all caused caries—holding a common belief that decay was due to chemical agents, faulty saliva, and food particles. Until the early 1800s most writers believed that caries was due to inflammation from surrounding diseased alveolar bone. …”
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Characterization of Ketoprofen/Methyl-β-Cyclodextrin Complexes Prepared Using Supercritical Carbon Dioxide by Mauro Banchero, Silvia Ronchetti, Luigi Manna

“…The supercritical treatment allows these pharmaceutical formulations to be prepared without the use of any auxiliary agents or organic solvents. The treated samples were characterized through differential scanning calorimetry, X-ray diffractometry, and the Fourier transform infrared spectroscopy to exclude the presence of crystalline drug and check the formation of the complexes. …”
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European distribution and intramuscular pathogenicity of divergent lyssaviruses West Caucasian bat virus and Lleida bat lyssavirus by Stefania Leopardi, Laurent Dacheux, Jordi Serra-Cobo, Ágota Ábrahám, Branka Bajić, Hervé Bourhy, Szilárd-Lehel Bücs, Ivana Budinski, Martina Castellan, Petra Drzewniokova, Heliana Dundarova, Francesca Festa, Lauriane Kergoat, Maxime Leuchtmann, Marc López-Roig, Dominique Pontier, Maria Francesca Priore, Emmanuelle Robardet, Dino Scaravelli, Barbara Zecchin, Zsófia Lanszki, Tamás Görföl, Gábor Kemenesi, Paola De Benedictis

“…Summary: Among lyssaviruses, West Caucasian bat virus (WCBV) and Lleida bat lyssavirus (LLEBV) raise concern as their divergence from rabies virus leads to the inefficacy of available prophylactic agents. Both viruses were described in the bat Miniopterus schreibersii. …”
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The Effect of Immunosuppressive Drugs on MDSCs in Transplantation by Fan Yang, Yang Li, Qian Zhang, Liang Tan, Longkai Peng, Yong Zhao

“…We hope to emphasize our concern for the negative effects of immunosuppressive agents on MDSCs, which may potentially attenuate the immune tolerance induction in transplanted recipients.…”
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Orkut e Facebook: as teias da memória em meio às redes sociais by Marcia Elisa Rendeiro

“…In the dynamics composed by the social networks, with sites that allow you to find and "increase the amount" of friends by specific features, create discussion groups and transit among albums and communities; we foresee the existence of a circuit that oppose word and image, a text with specific narrative features, a kind of a virtual device that stimulates the generation of memories and representation - links of a same chain that serves to punctuate the writing of the social memory and the formation of new identities.…”
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Solvent extraction of uranium from an acidic medium for the front-end of nuclear fuel cycle: from mechanisms understanding to innovative process design by Giusti, Fabrice, Guerinoni, Elise, Lemire, David, Thimotée, Marine, Arrachart, Guilhem, Dourdain, Sandrine, Pellet-Rostaing, Stéphane

“…To address this challenge, researchers have developed a wide range of new extracting molecular agents that allow efficient and selective liquid–liquid extraction of the target metal. …”
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Urinary bacteriophage cooperation with bacterial pathogens during human urinary tract infections supports lysogenic phage therapy by Mahmood Almosuli, Anna Kirtava, Archil Chkhotua, Lia Tsveniashvili, Nina Chanishvili, Sumaiya Safia Irfan, Emily Ng, Hope McIntyre, Adam J. Hockenberry, Robyn P. Araujo, Weidong Zhou, Ngoc Vuong, Barbara Birkaya, Lance Liotta, Alessandra Luchini

“…From a human health perspective, these data suggest that temperate phages may facilitate bacterial infections rather than function as protective agents. These findings support the use of lysogenic phages as therapeutic Trojan Horses.…”
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