Targeted therapy and immunotherapy for gastric cancer: rational strategies, novel advancements, challenges, and future perspectives by Dong Luo, Yunmei Liu, Zhengmao Lu, Lei Huang

“…To address intrinsic and acquired resistances to HER2-targeting drugs, novel therapeutic agents including bispecific antibodies and antibody–drug conjugates (ADC) targeting HER2 have been developed. …”
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Postcards from Inside the Practices by Alicia Lazzaroni, Antonio Bernacchi, Enrique Espinosa Pérez, Lydia Maria Arantes, Michele Avis Feder-Nadoff

“…The study, therefore, brings together agents (regulations, hacks, agreements, and agents); resources (affections, desires, frustrations, communication channels, economic precariousness, etc.); and actions (agreements, exchanges, self-constructions, doubts, and decisions) that go beyond the client-technician or problem-solution relationships.   …”
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La diversidad cultural en el currículo: un reto para el profesorado de las Ciencias Médicas by Norma Mur Villar, Miriam Iglesias León, María Aurelia San Juan Bosch, Manuel Cortés Cortés, Yaan Manuel Quintana Santiago

“…Sin embargo, la diversidad cultural en este escenario continúa siendo aún un reto para el profesorado, ya que el currículo implanta una cultura nacional que se aleja de la diversidad cultural que impone estos tiempos. …”
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Chinese stroke association guidelines on reperfusion therapy for acute ischaemic stroke 2024 by Liping Liu, Anding Xu, Xin Wang, Yongjun Wang, Yilong Wang, Zhongrong Miao, Yuming Xu, Benyan Luo, Bin Peng, Yong Huo, Qiang Dong, Zixiao Li, Xingquan Zhao, Caiyun Wang, Hongqiu Gu, Chunjuan Wang, Zhengqi Lu, Yunyun Xiong, Shuo Wang, Lihua Wang, Linong Ji, Xiaoping Gao, Wenzhi Wang, Yi Yang, Kai Wang, Junbo Ge, Xunming Ji, Jun Pu, Tong Zhang, Bo Hu, Ning Wang, Yun Xu, Jinsheng Zeng, Gang Zhao, Zhong Chen, Aoming Jin, Xiaoyuan Niu, Jiong Shi, Shuya Li, Jianmin Zhang, Ling Yin, Dou Li, Dehong Lu, Chao Qin, Dapeng Sun, Kaifu Ke, Yanhui Du, Xiaoning Zhang, Fudong Shi, Jianxin Zhou, Lan Chu, Li Guo Li He, Shengnian Zhou, Weixin Cai, Xiaomu Wu, Zhiyi He

“…Additionally, the guideline includes green channel flow charts for intravenous thrombolysis and mechanical thrombectomy, designed to assist clinicians in optimising their clinical decisions.Conclusion This guideline updates the latest advancements in the field of reperfusion therapy for acute ischaemic stroke. It is anticipated that future clinical research will further advance areas such as innovative thrombolytic agents, expanded indications for thrombolysis and mechanical thrombectomy.…”
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Real world data on outcomes of anti-CD38 antibody treated, including triple class refractory, patients with multiple myeloma: a multi-institutional report from the Canadian Myeloma... by A. Visram, A. De La Torre, D. White, J. Su, E. Masih-Khan, M. Chu, V. Jimenez-Zepeda, A. McCurdy, R. LeBlanc, K. Song, H. Mian, M. Louzada, M. Sebag, D. Bergstrom, J. Stakiw, A. Reiman, R. Kotb, M. Aslam, C. Venner, R. Kaedbey, E. Gul, D. Reece

“…Abstract Multiple myeloma (MM) remains incurable despite the availability of novel agents. This multi-center retrospective cohort study used the Canadian Myeloma Research Group Database to describe real-world outcomes of patients withanti-CD38 monoclonal antibody (mAb) refractory MM subsequently treated with standard of care (SoC) regimens. …”
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The Use of Specific Non-<i>Saccharomyces</i> Yeasts as Sustainable Biocontrol Solutions Against <i>Botrytis cinerea</i> on Apples and Strawberries by Zukisani Gomomo, Morris Fanadzo, Maxwell Mewa-Ngongang, Boredi Silas Chidi, Justin Wallace Hoff, Marieta van der Rijst, Lucky Mokwena, Mathabatha Evodia Setati, Heinrich Wilbur du Plessis

“…In volatile organic compound (VOC) assays, <i>P. kluyveri</i> and <i>S. pyralidae</i> achieved 79% and 56% inhibition, respectively, with VOCs like isobutanol, isoamyl alcohol, 2-phenylethanol, isoamyl acetate, and 2-phenethyl acetate identified. In post-harvest trials, <i>S. pyralidae</i> was most effective on apples, with inhibition rates up to of 64%. …”
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An Evidence-Based Update on the Impact of Local Antimicrobials as Adjunct to Periodontal Therapy by Nabaz Yahya Hussein, Sadat Abdulla Aziz, Twana Mohammed M. Ways, Omed Amiri, Hisham Al-Obaidi, Dianne Ford

“…MTZ showed the lowest clinical improvement among the agents reviewed, but it remains valuable due to its targeted action against anaerobic bacteria, which are prominent in periodontal infections. …”
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Bacterial blood microbiome of Mastomys rodents: implications for disease spill-over at the animal-human interface within the Bushbuckridge-East community, South Africa by Agatha O. Kolo, Agatha O. Kolo, Kelly A. Brayton, Kelly A. Brayton, Nicola E. Collins, Armanda D. S. Bastos, Armanda D. S. Bastos, Armanda D. S. Bastos, Sonja Matthee, Cory A. Gall, Jeanette Wentzel, Jeanette Wentzel, Luis Neves, Luis Neves, Marinda C. Oosthuizen

“…The detection of zoonotic agents in rodents in Bushbuckridge-East community, together with prior serological confirmation of Bartonella and Coxiella in non-malarial acute febrile patients from this community, highlights the possible risks that commensal rodents pose to human health.…”
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Synthesis and evaluation of nitrochromene derivatives as potential antileishmanial therapeutics through biological and computational studies by Niloofar Javid, Ali Asadipour, Ehsan Salarkia, Mohammad Amin Langarizadeh, Fatemeh Sharifi, Mohammad Mahdavi, Bagher Amirheidari, Aida Iraji, Hojjat Rezaiezadeh, Gholamreza Hassanpour, Yaghoub Pourshojaei

“…In light of these limitations, developing new therapeutic agents that can effectively disrupt the parasite’s life cycle at multiple stages is of paramount importance. …”
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Tacrolimus- and Mycophenolate-Mediated Toxicity: Clinical Considerations and Options in Management of Post-Transplant Patients by Alan D. Kaye, Shivam S. Shah, Coplen D. Johnson, Adalyn S. De Witt, Austin S. Thomassen, Charles P. Daniel, Shahab Ahmadzadeh, Sridhar Tirumala, Kristin Nicole Bembenick, Adam M. Kaye, Sahar Shekoohi

“…Tacrolimus and mycophenolate are important immunosuppressive agents used to prevent organ rejection in post-transplant patients. …”
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"A. JACOBI NAS LIÇÕES SOBRE A HISTÓRIA DA FILOSOFIA" DE GEORG WILHELM FRIEDRICH HEGEL by Gabriel Rodrigues da Silva, Robson Caixeta Silva

“…O recorte em questão encontra-se no vigésimo volume (Band 20) da edição Theorie Werkausgabe (TWA), organizada por Karl Markus Michel e Eva Moldenhauer, e publicada pela editora alemã Suhrkamp em 1986. …”
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INTEGRATING HYPERTONIA REHABILITATION, INTRAORAL REHABILITATION, AND ANXIETY MANAGEMENT FOR COMPREHENSIVE PATIENT CARE- PART1 by Lucian Stefan Burlea, Doriana Agop Forna, Mihaela Salceanu, Violina Budu, Vlad Proca, Bogdan Petru Bulancea, Tudor Hamburda, Maria Antonela Beldiman

“…As premedication, miorelaxants, adjuvants for inflammatory processes (which result in antalgic hypertonic phenomena), and during local anesthesia through neuromuscular transmission blockage, miorelaxants are a class of pharmacological agents with various structures and mechanisms of action that are highly helpful in treating stomatognatic dysfunctions. …”
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On Priority in Multi-Issue Bankruptcy Problems with Crossed Claims by Rick Acosta-Vega, Encarnación Algaba, Joaquín Sánchez-Soriano

“…In this paper, we analyze the problem of how to adapt the concept of priority to situations where several perfectly divisible resources have to be allocated among a certain set of agents that have exactly one claim that is used for all resources. …”
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The Link between Allergic Rhinitis and Asthma: A Role for Antileukotrienes? by H Kim, J Bouchard, PM Renzix

“…The present article reviews the shared components of allergic rhinitis and asthma, and examines recent evidence supporting antileukotrienes as effective agents in reducing the symptoms of both diseases.…”
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La réforme des curriculums par compétences au Bénin by Basile Agbodjogbé, Chantal Amade-Escot, Kossivi Attiklèmè

“…The content analysis of their discourses was conducted through the ALCESTE software. The findings point out four classes of discourses, each of them related to different viewpoints. …”
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The Hepatitis C Genotype 1 Paradox: Cost per Treatment Is Increasing, but Cost per Cure Is Decreasing by Stephen D Shafran

“…Significant attention has been focused on the perceived increase in the cost of antiviral treatment for hepatitis C genotype 1 infection since the approval of the first direct-acting antiviral agents in 2011. Using Canadian list prices, the present analysis points out a paradox: while the cost per antiviral regimen is increasing, the cost per cure is decreasing, especially with interferon-free therapy. …”
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Determination of the Thermal Diffusivity of Plasmonic Nanofluids Containing PVP-Coated Ag Nanoparticles Using Mode-Mismatched Dual-Beam Thermal Lens Technique by C. S. Lopes, V. M. Lenart, R. F. Turchiello, S. L. Gómez

“…Plasmonic nanofluids have found applications in many fields, for example, coolants, solar collectors, and theranostics agents. For such applications, an important parameter is the thermal diffusivity. …”
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Río Bec. Des grandes maisons et des récoltes by Marie-Charlotte Arnauld, Dominique Michelet, Chloé Andrieu, Alfonso Lacadena, Éva Lemonnier, Boris Vannière, Philippe Nondédéo, Julie Patrois

“…The picture is one of a highly fragmented society consisting of many economically autonomous agents, each pursuing corporate interests that combined intensive staple production and auto-construction of stable residences on their land, with minimal insertion in craft production and regional exchanges.…”
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Conducting a Blue Dye Demonstration to Teach Irrigation and Nutrient Management Principles in a Residential Landscape by George Hochmuth, Laurie Trenholm, Esen Momol, Don Rainey, Claire Lewis, Brian Niemann

“…The information should be useful for county agents to demonstrate basic irrigation and nitrogen management practices and their effects on nitrate-nitrogen (N) leaching. …”
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Acquired Hemophilia A (FVIII Deficiency) Associated with Papillary Thyroid Cancer: Treatment with Recombinant Porcine FVIII by S. Nguyen, P. Teh, J. Zhou, E. Y. Chang, A. von Drygalski

“…FVIIa-based bypassing agents are the first line of treatment but not always effective. …”
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