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27781
Therapeutic efficacy of LysGH15 against necrotising pneumonia caused by Staphylococcus aureus in a rabbit model
Published 2025-02-01“…In addition, LysGH15 treatment alleviated lung tissue damage in infected rabbits and significantly reduced the levels of Panton-Valentine leukocidin (PVL), alpha-toxin (Hla), and the cytokines IFN-γ, TNF-α, and IL-8 in their lung tissues, similar to those in rabbits treated with linezolid.DiscussionThese results suggest that LysGH15 has the potential to be used as a novel antimicrobial agent for the treatment of necrotising pneumonia caused by S. aureus.…”
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27782
Lycium barbarum glycopeptide ameliorates aging phenotypes and enhances cardiac metabolism by activating the PINK1/Parkin-mediated mitophagy pathway in D-galactose-induced mice
Published 2025-02-01“…These findings underscore its potential as a therapeutic agent for aging and aging-related cardiovascular diseases.…”
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27783
Poverty Dynamics and the Fundamental Root Causes in Iran
Published 2024-12-01“…This method is a tool to show cause and effect relationships about a problem in society. This approach maps the relationships of a set of variables involved in a system. …”
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27784
Excess costs of post-traumatic stress disorder related to child maltreatment in Germany
Published 2025-01-01“…While the high economic burden of PTSD is well-documented, little is known about the health care cost differences between individuals with PTSD-CM and those without PTSD in Germany. …”
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27785
Development of a comprehensive model to predict stock prices in the stock market with an interpretive structural modeling approach
Published 2024-06-01“…On the other hand, fundamental analysis is based on the information about companies and the broader economy, focusing more on long-term forecasts and investment strategies (Latif et al., 2024). …”
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27786
Modern theoretical-methodological and economic-legal problems of implementing the concept of sustainable development of tourism and recreation in Ukraine
Published 2024-10-01“…In many countries, this sector plays a key role in the economy, accounting for about 50% of budget revenues, that is, it is one of the main sources of income for these countries. …”
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27787
Call for Papers: Demography Prize for Young Researches 2016/2017
Published 2016-12-01“…Through the prize, the FRFG and IF seek to promote discussion about intergenerational justice in society, and, by providing a scholarly basis to the debate, establish new perspectives for decision-makers. …”
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27788
Pragmatic algorithm for visual assessment of 4-Repeat tauopathies in [18F]PI-2620 PET Scans
Published 2025-02-01“…Results: Patients with 4R-tauopathies in contrast to non-4R-tauopathies were detected at higher sensitivity in the 20–40-minute frame (common: 79%, scaled: 76%) compared to the 40–60-minute frame (common: 55%, scaled: 62%), albeit with reduced specificity in the common setting (20–40-min: 78%, 40–60-min: 95%), which was ameliorated in the intensity-scaled setting (20–40-min: 91%, 40–60-min: 96%). …”
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27789
Physiological accumulation of lipid droplets in the newborn liver during breastfeeding is driven by TLR4 ligands
Published 2025-02-01“…The liver plays a central role in fat storage, but little is known about physiological fat accumulation during early development. …”
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27790
Path and Practice of Gap Management in National Parks: A Comparison Between China and the US and Inspirations Therefrom
Published 2025-02-01“…However, this approach raises concerns about ecological integrity, particularly when it leads to fragmentation, reduced connectivity, and potential ecological risks. …”
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27791
Co‐Translational Deposition of N6‐Acetyl‐L‐Lysine in Nascent Proteins Contributes to the Acetylome in Mammalian Cells
Published 2025-01-01“…Abstract N6‐acetyl‐L‐lysine residue is abundant in dietary protein but little is known about its potential influences on the diet‐consumers. …”
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27792
Evaluation of Urban Composite Carbon Sink Value: A Case Study of Shenyang
Published 2025-01-01“…With the increasing concerns about climate change and the pursuit of sustainable development, accurately evaluating the carbon sink value becomes essential for understanding the role of different ecosystems in carbon cycling. …”
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27793
Osiąganie kompromisu potrzeb człowieka i przyrody
Published 2004-12-01“…Only by considering and deciding about ecoengineering alternatives we can choose the more appropriate method of handling with the natural environment. …”
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27794
Détection de différents rétrovirus chez des primates non-humains infectés par STLV-1 ou SFV et pathologie viro-induite
Published 2015-03-01“…Tandis que l'infection par SFV est asymptomatique, STLV-1, comme HTLV-1 est l'agent étiologique de la Leucémie/Lymphome T de l'adulte. …”
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27795
Çin Siyasi Düşüncesi ve Siyasi Tarihi Bağlamında Çinli Siyasi Elitler
Published 2024-12-01“…The book's comparative analysis adds a unique layer, encouraging readers to think about modernization and elite politics in a global context. …”
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27796
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27797
Evolution of Green Technology, Technology Gap and International Trade A Comparative Study of Developing and Developed Countries
Published 2024-12-01“…Although economic growth is one of the main goals of countries, developed economies are more concerned about its environmental consequences. Unfortunately, it seems that developing countries often overlook environmental protection in their pursuit of desired economic growth. …”
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27798
Slow Metabolism–Driven Amplification of Hepatic PPARγ Agonism Mediates Benzbromarone‐Induced Obesity‐Specific Liver Injury
Published 2025-01-01“…The previous study demonstrates that benzbromarone (BBR), a commonly prescribed pharmaceutical agent for managing gout and hyperuricemia, exacerbates hepatic steatosis and liver injury specifically in obese individuals. …”
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27799
AlphaFold-based AI docking reveals AMPK/SIRT1-TFEB pathway modulation by traditional Chinese medicine in metabolic-associated fatty liver disease
Published 2025-02-01“…These findings suggest that QGJZF as a therapeutic agent in augmenting autophagy-facilitated lipid clearance for the management of MAFLD via AMPK/SIRT1-TFEB axis.…”
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27800
Rome à la campagne : les décors en pierre de la villa de la Grande Boussue à Nouvelles (Mons, Belgique)
Published 2023-12-01“…These are associated with a wall mosaic made of glass paste including 1570 tesserae of various colours, some of which are enhanced with gold leaf.Between these two rooms, a tank and a service room of about 20 m2 were discovered. The remains of a cooking hearth next to the wall adjoining the tank and the presence of animal bones and oysters on the floor, show that this place was also used for culinary activities. …”
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