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27761
LRP11 promotes stem-like T cells via MAPK13-mediated TCF1 phosphorylation, enhancing anti-PD1 immunotherapy
Published 2024-01-01“…In contrast to the finding that TCF1 controls epigenetic and transcriptional reprogramming in tumor-infiltrating stem-like T cells, little is known about the regulation of TCF1. Emerging data show that elevated body mass index is associated with outcomes of immunotherapy. …”
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27762
Hypertension Subtypes among Thai Hypertensives: An Analysis of Telehealth-Assisted Instrument in Home Blood Pressure Monitoring Nationwide Pilot Project
Published 2020-01-01“…However, little is known about the true prevalence in Thailand. Objectives. …”
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27763
Effects of dietary compound acidifier (Biomin) on the growth, anti-oxidation, immunity, and intestinal health of juvenile channel catfish (Ictalurus punctatus)
Published 2025-03-01“…Six experimental diets (about 36 % crude protein and 5 % crude lipid) were prepared with graded levels of dietary CA (0 (control), 0.05 %, 0.10 %, 0.20 %, 0.40 %, and 0.80 %). …”
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27764
AKRASIJA IR SUBJEKTAS EGONOMIKOJE
Published 2000-01-01“…He redescribes the relationship between Me and I in the vocabulary used by new institutional economics to analyse the relations between principal and agent. When the self in the neobuddhist perspective is fragmented into the temporally successive "subselves", their relations can be described in terms of bargaining theory, collective action theory, social choice theory, game theory, and the theory of distributive justice. …”
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27765
Occurrence of micropollutants in surface water and removal by catalytic wet peroxide oxidation enhanced filtration using polymeric membranes loaded with carbon nanotubes
Published 2025-03-01“…Even in such small concentrations, the contaminants can be harmful to aquatic life. Therefore, for about three months, passive samplers were used to monitor the presence of pharmaceuticals in river water up- and downstream the discharge of a wastewater treatment plant (WWTP). …”
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27766
Age-related calcium signaling disturbance restricted cAMP metabolism and induced ovarian oxidation stress in laying ducks
Published 2025-01-01“…Fortunately, medium supplemented with Ca channel-activator A23187 enhanced GC viability, antioxidant ability, tight junction ability, and increased cAMP concentration by improved cAMP metabolism, otherwise, the opposite changes were observed with Ca2+-chelating agent EGTA or Ca channel-inhibitor Verapamil supplementation. …”
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27767
Accurate space-based NO<sub><i>x</i></sub> emission estimates with the flux divergence approach require fine-scale model information on local oxidation chemistry and profile shapes
Published 2025-02-01“…Here we test the capability of the FDA to reproduce known <span class="inline-formula">NO<sub><i>x</i></sub></span> emissions from synthetic <span class="inline-formula">NO<sub>2</sub></span> column retrievals generated with the LOTOS-EUROS chemistry transport model over the Netherlands at high spatial resolution of about <span class="inline-formula">2×2</span> <span class="inline-formula">km</span> during summer. …”
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27768
Макроморфологічні та мікроморфологічні дослідження ґрунтів Консулівського городища (І ст. до н. е. – ІІ ст. н. е.)...
Published 2024-12-01“…Він відповідає за ознаками більш сухішим умовам ґрунтоутворення. It is about the continuation of the geoarchaeological research at Konsulivska hillfort (Republicanets village, Beryslav district, Kherson region). …”
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27769
Immunomodulation by allograft endothelial cells
Published 2025-02-01“…However, little is known about tissue-intrinsic immunomodulatory mechanisms following transplantation. …”
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27770
Neoandrographolide inhibits mature osteoclast differentiation to alleviate bone loss and treat osteoporosis
Published 2025-02-01“…In vivo experiments further validated the in vitro findings by constructing an OP model, showing that NEO can mitigate bone loss induced by OC differentiation.ConclusionNEO has the potential to serve as a therapeutic agent for OP by targeting multiple sites and inhibiting the formation of mature OC through various signaling pathways.…”
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27771
The novel H10N3 avian influenza virus acquired airborne transmission among chickens: an increasing threat to public health
Published 2025-02-01“…ABSTRACT Following two human infections with the H10N3 avian influenza virus (AIV) in 2021 and 2022, a third case was discovered in Yunnan, China, in 2024, raising concerns about the potential for future pandemics. Recent studies have indicated that novel H10N3 viruses are highly pathogenic in mice and can be transmitted between guinea pigs via respiratory droplets without prior adaptation. …”
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27772
Estimating Suitable Areas for Dry Almond (Amygdalus communis L.) Cultivation Development in Fars Province using Geographic Information System (GIS)
Published 2025-12-01“…However, the suitability of about 17.09% of the region for almond cultivation is low, and 5.01% of the province area is unsuitable for almond cultivation. …”
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27773
A Systematic Review of the Cost-Effectiveness of Nurse Practitioners and Clinical Nurse Specialists: What Is the Quality of the Evidence?
Published 2014-01-01“…Incomplete reporting of study methods and lack of details about NP or CNS education, experience, and role create challenges in consolidating the evidence of the cost-effectiveness of these roles.…”
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27774
Nicotine’s impact on platelet function: insights into hemostasis mechanisms
Published 2025-01-01“…These findings suggest the potential utility of nicotine as a hemostatic agent.…”
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27775
Pre-operative DNA methylation marks as predictors of weight loss outcomes after sleeve gastrectomy
Published 2025-02-01“…Objective: Although DNA methylation has been suggested to be a potential predictor of the progression of obesity and obesity-related diseases, little is known about its potential role as predictive marker of successful weight loss after bariatric surgery. …”
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27776
The anti-circumsporozoite antibody response to repeated, seasonal booster doses of the malaria vaccine RTS,S/AS01E
Published 2025-02-01“…However, there is little information about the immune response to repeated booster doses of RTS,S/AS01E. …”
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27777
HIV self-testing alone or with additional interventions, including financial incentives, and linkage to care or prevention among male partners of antenatal care clinic attendees in...
Published 2019-01-01“…Women were interviewed at 28 days about partner testing and adverse events. Cluster-level summaries compared each intervention versus SOC using eligible women as the denominator (intention-to-treat). …”
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27778
Student Engagement and Feedback on Online Learning and Facilitation: A Case Study of the National Open University of Nigeria
Published 2024-12-01“…Il est important que NOUN s'attaque à ces problèmes en proposant des horaires plus souples, en explorant les possibilités de réduire les coûts de facilitation et en veillant à ce que les étudiants aient accès à une connexion Internet stable afin d'améliorer leur engagement dans les facilitations en ligne. …”
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27779
HPLC-MS standardization and validation methods for determination of calactin content in dichloromethane fraction of Calotropis gigantea (L.) Dryand. (Niu jiao gua) stem bark and it...
Published 2025-02-01“…This phytochemical has gained recognition for its potential as an anticancer agent and a marker for anticancer properties. Our previous reports demonstrated the remarkable anti-liver and anti-colon cancer activities both in vitro and in vivo of the dichloromethane fraction from the stem barks of C. gigantea (CGD). …”
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27780
Diagnosis and treatment of the irritable bowel syndrome: clinical guidelines of the Russian gastroenterological association and Russian association of coloproctology
Published 2018-08-01“…Enterokinetic agent prucalopride may be prescribed at inefficacy of laxatives. …”
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