Aspirin Modulates Innate Inflammatory Response and Inhibits the Entry of Trypanosoma cruzi in Mouse Peritoneal Macrophages by Aparecida Donizette Malvezi, Rosiane Valeriano da Silva, Carolina Panis, Lucy Megumi Yamauchi, Maria Isabel Lovo-Martins, Nagela Ghabdan Zanluqui, Vera Lúcia Hideko Tatakihara, Luiz Vicente Rizzo, Waldiceu A. Verri, Marli Cardoso Martins-Pinge, Sueli Fumie Yamada-Ogatta, Phileno Pinge-Filho

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Fraxinellone-mediated targeting of cathepsin B leakage from lysosomes induces ferroptosis in fibroblasts to inhibit hypertrophic scar formation by Wei Xu, Hao Lv, Yaxin Xue, Xiaofeng Shi, Shaotian Fu, Xiaojun Li, Chuandong Wang, Danyang Zhao, Dong Han

“…Therefore, FRA could be a promising therapeutic agent for treating HS.…”
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Non Linear Thermal Radiation Analysis of Electromagnetic Chemically Reacting Ternary Nanofluid Flow over a Bilinear Stretching Surface by Shobha V, Hasan Mulki, Baskar P, S. Suresh Kumar Raju, Saleh Mahmoud, Mostafa Abdrabboh, S.V.K. Varma

“…Results and Conclusions: The analysis reveals that key parameters, such as magnetic field strength, stretching ratio, and rotational effects, significantly influence heat transfer and flow characteristics.In Model-1, the percentage increase in heat transfer due to an increase in nanoparticle volume fraction (ϕ₂) is approximately 0.50%, while in Model-2, it is around 0.35%.For the stretching ratio, Model -1 shows a transfer rate increase of about 29.01%, while Model -2 shows an increase of approximately 29.12%.Radiation effects expand the momentum layer and enhance the primary velocity in both cases. …”
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A nursing and midwifery training program in Kathmandu on antimicrobial resistance and stewardship and infection prevention and control: a qualitative and quantitative outcomes and... by Jamuna Tamrakar Sayami, Rakchya Amatya, Kshitij Karki, Deepak Bajracharya, Basudha Shrestha, Sreenidhi Srinivasan, Tyler Prentiss, Anita Shallal, Marcus Zervos, Katie Latack, Linda Kaljee

“…Key outcomes were AMS and IPC knowledge, and decision-making about empirical dispensing of antibiotics. The process evaluation focused on training content, integration into practice, implementation barriers, and recommendations for dissemination. …”
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Assessment of Birth Preparedness and Complication Readiness among Pregnant Women: A Cross-sectional Study by T Elamathi, K Ananthi, Rimi Singh

“…Introduction: Ropivacaine is a long-acting amide local anaesthetic agent and the pure S (-) enantiomer of propivacaine. …”
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The Prevalence of Depression Among Parkinson’s Disease Patients in Saudi Arabia: A Cross-Sectional Study by Al-Qahtani Z, Alqahtani ASM, Alzuhairi AMS, Qarah M, Alqarni AA, Alqahtani AOM, AlShehri FAA, Alqathanin MAA, Alshahrani OMO, Alqahtani MAF, Mahmood SE

“…Zainah Al-Qahtani,1 Abdulrahman Saad M Alqahtani,2 Abdulmohsin Mohammed S Alzuhairi,3 Mohammed Qarah,4 Albara A Alqarni,3 Abdulaziz Othman M Alqahtani,5 Fahad Abdullah A AlShehri,3 Muath Abdullah A Alqathanin,6 Omair Mohammed O Alshahrani,3 Mohammed Ali F Alqahtani,5 Syed Esam Mahmood7 1Neurology Section, Internal Medicine Department, College of Medicine, King Khalid University, Abha, 61421, Saudi Arabia; 2Aseer Cluster Health, Abha, Saudi Arabia; 3King Khalid University, Abha, Saudi Arabia; 4Public Health Department, Saudi Board of Preventive Medicine, Madinah, Saudi Arabia; 5College of Medicine King Khalid University, Abha, Saudi Arabia; 6Internal Medicine Department, Saudi Board of Internal Medicine, Abha, Saudi Arabia; 7Department of Family and Community Medicine, College of Medicine, King Khalid University, Abha, 61421, Saudi ArabiaCorrespondence: Syed Esam Mahmood, Department of Family and Community Medicine, College of Medicine, King Khalid University, Abha, 62529, Saudi Arabia, Email smahmood@kku.edu.saBackground and Aim: Depression is thought to affect up to half of Parkinson’s patients at some point during their illness, while anxiety is reported by about 40% of PD patients. The study aimed to assess the prevalence of depression and anxiety among patients with Parkinson’s disease (PD) in Saudi Arabia.Methods: The study involved Saudi Arabian citizens and residents aged 40 or older with PD, who completed internet-survey (including online and email-based data collection) or telephone-survey by trained interviewers. …”
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The Rearing of Clown Loach (Chromobotia macracanthus) Larvae by Using Enriched Live Foods by . Chumaidi, . Nurhidayat, A. Priyadi

“…The treatment were: a) Artemia nauplii as control;  b) rotifer without enrichment;  c) enriched rotifer, d) Moina nauplii without enrichment, and e) enriched Moina nauplii.  As enrichment agent, we used 200 mg of tuna eggs powder and 200 mg of baker's yeast which dissolved and  aerated in 2 L of water for one hour.  …”
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Efficacy of Intrathecal 0.75% Hyperbaric Ropivacaine versus 0.5% Hyperbaric Bupivacaine for Elective Inguinal and Perineal Surgery: A Randomised Double-blinded Clinical Study by Bhavini Shah, Dipanjali Mahanta

“…Bupivacaine, a longer-acting agent that provides dense motor blockade, is known to carry a higher risk of re-entrant arrhythmias and cardiac depression with accidental intravascular injection. …”
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Species evolution: cryptic species and phenotypic noise with a particular focus on fungal systematics by Anusha H. Ekanayaka, Anusha H. Ekanayaka, Samantha C. Karunarathna, Samantha C. Karunarathna, Saowaluck Tibpromma, Arun Kumar Dutta, Danushka Sandaruwan Tennakoon, Anuruddha Karunarathna, Ekachai Chukeatirote, Dong-Qin Dai, Steven L. Stephenson, Sajeewa S. N. Maharachchikumbura, Chao Liu, Alan J. L. Phillips

“…Hence, the cryptic species concept refers to genetic variations, while the phenotypic noises concept is about non-genetic variations. Although both concepts are opposites, they each contribute significantly to the evolutionary process of an organism. …”
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Frequency and factors associated with loss to follow-up in newly diagnosed rheumatoid arthritis patient: a single-centre study by Sumariyono Sumariyono, Rudy Hidayat, Faisal Parlindungan, Suryo Anggoro Kusumo Wibowo, Anna Ariane, Johanda Damanik, Abirianty Priandani Araminta, Ryzkianty Annis Nurdin

“…The reasons for LTFU were distance from house to hospital constraints (76%), busy (56%), transportation constraints (38%), dissatisfaction with the outpatient clinic service (21%), lack of information about their disease (18%), having other comorbidities that compelled them to go to another department’s clinic (15%), difficulties understanding the clinic registration flow system (9%), and having minimal symptoms (6%). …”
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Prospective Evaluation of Unprocessed Core Needle Biopsy DNA and RNA Yield from Lung, Liver, and Kidney Tumors: Implications for Cancer Genomics by Mikhail T. Silk, Nina Mikkilineni, Tarik C. Silk, Emily C. Zabor, Irina Ostrovnaya, Ari A. Hakimi, James J. Hsieh, Etay Ziv, Natasha Rekhtman, Stephen B. Solomon, Jeremy C. Durack

“…., formalin fixation and paraffin embedding (FFPE)) has been previously reported, little is known about the potential yield for molecular analysis at the time of biopsy sample acquisition. …”
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Childhood wasting and associated factors in Africa: evidence from standard demographic and health surveys from 35 countries by Tadesse Tarik Tamir, Alebachew Ferede Zegeye, Belayneh Shetie Workneh, Mohammed Seid Ali, Almaz Tefera Gonete, Masresha Asmare Techane, Mulugeta Wassie, Alemneh Tadesse Kassie, Medina Abdela Ahmed, Sintayehu Simie Tsega, Yilkal Abebaw Wassie, Berhan Tekeba, Enyew Getaneh Mekonen

“…Childhood wasting, a severe form of malnutrition, indicates acute undernutrition, leading to significant loss of muscle and fat tissue. …”
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An analysis of the Policy of Increasing the Salaries of Government Employees Based on the Framework of Kingdon's Multiple Streams (Case Study of Budget Law 1401) by Seyyed Mojtaba Shahraeini, Heidar Najafi, Seyyedamir Abbaszade, Mahdi Khosravi, Iman Akbari

“…For example, employees earning 6 million Tomans in 1400 experienced a 12% net salary increase (after tax deductions), while those earning 32 million Tomans in 1400 saw about a 19% increase. The studies indicate that this unfair policy, which contradicts the prevailing discourse of the legislative and executive branches, was more influenced by the ignorance of policymakers in the government, parliament, and Guardian Council than by the economic and political interests of various stakeholders. …”
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Transprofessional education in the student discourse: Demand, expectations, risks by A. N. Pinchuk, S. G. Karepova, D. A. Tikhomirov

“…At the same time, the students spoke most of all about the need for experience in mastering the related branches of specialisation. …”
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Compulsive Buying Disorder among Medicine, Dentistry, and Nursing Undergraduate Students from Chengalpattu District, Tamil Nadu, India: A Cross-sectional Study by A Hari Narayanan, Vedapriya Dande Rajasekar, Raja Danasekaran, BN Surya, P Manoj, S Madhush Kumar, Rehana Syed, R Harishma

“…Significant associations with CBD included female gender, medical education, family history of shopaholics, online shopping, shopping-induced euphoria, anxiety or distress when unable to shop, and lying to family or friends about shopping expenses (p-value <0.05). Conclusion: The study revealed that 29.7% of undergraduate students exhibited Compulsive Buying Behaviour (CBB). …”
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Antifungal activity and biocompatibility assessment with molecular docking and dynamic simulations of new pyrazole derivatives by Basma T. Abd-Elhalim, Ghada G. El-Bana, Ahmed F. El-Sayed, Ghada E. Abdel-Ghani

“…Objective The current work validates the results and pyrazole binding sites as potent antifungals by investigating many pyrazole derivatives as antifungal agents. The biocompatibility was assessed using an HFB4 normal human skin cell line. …”
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Health-Related Quality of Life in Patients with Friedreich Ataxia Using Mobility Assistive Technologies: Limited Fit of the EQ-5D-3L Mobility Dimension by Maresa Buchholz, Michelle Pfaff, Audrey Iskandar, Kathrin Reetz, Jörg B. Schulz, Marcus Grobe-Einsler, Thomas Klockgether, Bernhard Michalowsky, EFACTS Study Group

“…To analyse the patients’ health-related quality of life (HRQoL), the EuroQol 5 Dimension 3 Level survey (EQ-5D-3L)—a widely used and recommended generic measure—is used in clinical and in health economic studies. Concerns about using the instrument in mobility-impaired individuals who might have difficulties finding appropriate response options for mobility-related items led us to investigate how the 3L dimensions perform in patients with FA using or not using MAT. …”
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The water year based on minimizing the terrestrial water storage variation and its validity by Changwu Cheng, Wenzhao Liu, Qiang Li, Tingting Ning, Haixiang Zhou, Zhaotao Mu, Kang Du, Kai Wang, Xiaoyang Han

“…However, a comprehensive quantitative investigation about its determination and usability in catchment water balance analysis remains absent. …”
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Identifying Touchpoints for Foreign Tourists in the Customer Journey through 5 A's Approach by Mostafa Esmaeili Mahyari, Mohammad Ghaffari, Hamid Reza Irani, Elham Ebrahimi

“…Finally, in the Advocacy stage, aspects like recommendation, defending against negative comments, willingness to revisit, bringing others in next travels, content creation on social media, and caring about Iran news play a role. ConclusionDuring all phases of a customer's journey, with particular emphasis on the Awareness and Ask stages, it is imperative to engage in advertising, content creation, and social media presence. …”
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Hubungan Lingkungan Fisik dan Tindakan Penduduk dengan Kejadian ISPA pada Balita di Wilayah Kerja Puskesmas Lubuk by Irma Suryani, Edison ., Julizar Nazar

“…<br />Kata kunci: ISPA balita, lingkungan fisik, tindakan penduduk</p><p>Abstract<br />The mortality rate due to Acute Respiratory Infections (ARI) in developing countries is about 20% which is 1/3-1/2 is the death of the children under five years old. …”
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