The value of metagenomic next-generation sequencing in the diagnosis of fever of unknown origin by Lan Min Lai, Qing-gen Chen, Yang Liu, Rui Zhao, Mei Ling Cao, Lei Yuan

“…Metagenomic next-generation sequencing (mNGS) technology is a promising diagnostic tool for identifying pathogenic microbes of FUO caused by infection. Little is known about the clinical impact of mNGS in the etiological diagnosis of FUO. …”
Get full text

Prevalence, Indications, and Community Perceptions of Caesarean Section Delivery in Ngora District, Eastern Uganda: Mixed Method Study by Isaac Waniala, Sandra Nakiseka, Winnie Nambi, Isaac Naminya, Margret Osuban Ajeni, Jacob Iramiot, Rebecca Nekaka, Julius Nteziyaremye

“…It highlights the need for male involvement during counseling and consent for CS and concerted efforts to demystify community misconceptions about women that undergo CS. These misconceptions may be a hindrance to access to CS.…”
Get full text

Value Propositions for Digital Shared Medication Plans to Boost Patient–Health Care Professional Partnerships: Co-Design Study by Benjamin Bugnon, Francesca Bosisio, Alain Kaufmann, Pascal Bonnabry, Antoine Geissbuhler, Christian von Plessen

“…We identified four value propositions for involving patients and family caregivers in digital SMP management: (1) comprehensive, accessible information about patients’ current medication plans and histories, enabling streamlined access and reconciliation on a single platform; (2) patient and health care professional empowerment through the explicit co-ownership of SMPs, fostering coresponsibility, accountability, and transparent collaboration; (3) a means of supporting collaborative interprofessional medication management, including tailored access to information and improved communication across stakeholders; and (4) an opportunity to improve the quality of care and catalyze digital health innovations. …”
Get full text

Examining the Impact of Cognitive and Emotional Factors on Consumer Behavioral Responses in Online Behavioral Advertising by Hossein Norouzi, Bahareh Osanlou, Ali Saleh Gohari

“…However, this raises concerns about consumer privacy. Some researchers have concentrated on the positive aspects of Online Behavioral Advertising (OBA), while others have delved into its negative implications. …”
Get full text

Calculation Method of Overburden Damage Height Based on Fracture Mechanics Analysis of Soft and Hard Rock Layers by Liang Chen, Shaowu Fan, Can Zhao, Lang Zhang, Zhiheng Cheng

“…Results showed that (1) by the calculation method, the overburden damage height of the N1102 fully mechanized caving face in Yuwu coal mine was 51.44 m, which was less than the value obtained by an actual borehole TV method as well as the numerical simulation result of 53.46 m, with a calculation accuracy about 96.22%, which is quite high for both. The calculation accuracy of the proposed method was higher than that of the three conventional theoretical methods, and it effectively solved the limitation of the fracture analysis method without the inclusion of the soft rock layer in design and the distortion problem due to the residual bulking coefficient to be improperly used in simulation. (2) There was no noticeable fractures in the broken soft rock zone, and the whole fractures were mainly low-angle rupture; the fractures in hard rock layer had obvious ruptures and multiangle cracks, and the average fracture width of soft rock was 2.8 mm smaller than that of hard rock. …”
Get full text

Effect of “Helping Babies Breathe” Training on Ethiopian Undergraduate Midwifery Students’ Knowledge and Skills in Neonatal Resuscitation at Public Universities: A Non-Randomized Q... by Endalew Gemechu Sendo, Girum Sebsibe Teshome, Wegnesh Kelbessa Jirata, Lemi Abebe Gebrewold, Rahel Endalew Gemechu

“…The results demonstrated that, although before the intervention, over 25% of research participants (18; 29.63%) lacked adequate knowledge about managing birth asphyxia, all of them acquired adequate knowledge[≥80%] after the intervention. …”
Get full text

The proof is in the pudding: patient engagement in studying cannabidiol in mild cognitive impairment by Antonia Keck, Julia-Sophia Scheuermann, Petra Scheerbaum, Elmar Graessel, Kirsten R. Müller-Vahl

“…Conclusions Our study identified cognitive improvement as highly relevant for patients, indicating cognitive assessment tools as primary endpoints in MCI research. Given concerns about AEs, dose titration should be carefully considered to enhance acceptance and prevent AEs. …”
Get full text

Traffic-related air pollution (TRAP) exposure, lung function, airway inflammation and expiratory microbiota: A randomized crossover study by Rongrong Xu, Yanping Zhang, Tingting Wu, Hao Liu, Jianhao Peng, Zhanshan Wang, Te Ba, Baorong Zhang, Zhigang Li, Yongjie Wei

“…TRAP including NO2 and CO in the road were about 1.5 times higher than that in the park except for PMs, and total VOCs also showed higher concentrations. …”
Get full text

Antioxidant, Anti-Tyrosinase, and Wound-Healing Capacities of Soy Protein Hydrolysates Obtained by Hydrolysis with Papaya and Cantaloupe Juices Showing Proteolytic Activity by Thi-Phuong Nguyen, Quang Thai Le, Mai Linh Thi Tran, Kim Nhung Ta, Khoa Thi Nguyen

“…Our analysis showed that SPI was hydrolysed by papaya juice, at the juice to substrate ratio of 2.5:2 ( v/ w), with a degree of hydrolysis (DH) of approximately 11% after 4 h of treatment at 55ºC. A higher DH (about 26%) was obtained by the hydrolysis with cantaloupe juice at the same juice to substrate ratio and treatment conditions. …”
Get full text

Health system costs of a breast cancer early diagnosis programme in a rural district of Rwanda: a retrospective, cross-sectional economic analysis by Lydia E Pace, Lawrence N Shulman, Jean Claude Mugunga, Parsa Erfani, Kayleigh Pavitra Bhangdia, Rashidah Nambaziira, Lysa Carolle Niteka, Jean Marie Vianney Dusengimana, John Ruhumuriza, Marie Louise Uwineza, Vestine Rugema, Cyprien Shyirambere, Melany Rabideau

“…In other districts, patients experience a longer breast evaluation pathway, adding about US$14.00/patient; this could be decreased if ultrasound services were decentralised.Conclusion Clinical costs associated with BCED services at HCs were modest, similar to other general outpatient services. …”
Get full text

Ultrasound-Guided Percutaneous Balloon Aortic Valvuloplasty for Aortic Stenosis by Yedan Li, Kunjing Pang, Yao Liu, Muzi Li, Hao Wang

“…Aortic peak jet velocity, aortic valve orifice area (AVA), mean transvalvular pressure gradient (MTPG), left ventricular end-diastolic diameter (LVDD), left ventricular ejection fraction (LVEF), and left ventricular end-systolic diameter (LVESD) were determined before and immediately after PBAV using Doppler echocardiography. …”
Get full text

Blood Glukose Response of Giant Gouramy (Osphronemus gaouramy, Lac.) to the Stress of Environmental Temperature Changes by S. Hastuti, Eddy Supriyono, Ing Mokoginta, . Subandiyono

“…Fish with body weight of about 52,15 g was used in the experiment. A hundred and twenty fish were subjected to stress by moving them to another aquarium containing cooler water for 5 minute before put them back to the origin aquarium. …”
Get full text

Prevalence of sexually transmitted infections and associated factors among male prisoners in Great Tehran Prison by active case finding by Behnam Farhoudi, Elnaz Shahmohamadi, Seyedahmad Seyedalinaghi, SeyedAlireza Nadji, Fatemeh Pahlaviani, Mehrzad Tashakorian

“…Conclusions Prisons are high-risk settings for transmission of STIs, while the prevention, screening, and treatment programs are not adequately developed. Educating prisoners about signs and symptoms, risk behaviors, STI preventive measures, regular screening of prisoners, and sufficient treatment can help control the STIs prevalence among the prisoners and, therefore, in the general population…”
Get full text

Reducing medical cannabis use risk among Veterans: A descriptive study by Laura M. Harris-Lane, Mitchell Sheehy, Courtney A. Loveless, Joshua A. Rash, David P. Storey, Gregory K. Tippin, Vikas Parihar, Nick Harris

“…Abstract Background Canadian Veterans experiencing chronic pain report concerns about accessing accurate information on the risks associated with medical cannabis (MC) use. …”
Get full text

Clinical burden of obstructive hypertrophic cardiomyopathy in France by Philippe Charron, Carla Zema, François-Emery Cotté, Eléonore Herquelot, Taryn Krause, Florent Daydé, Jean-Noël Trochu

“…BackgroundHypertrophic cardiomyopathy (HCM) can be genetic and occurs as obstructive and non-obstructive 21 subtypes. Little is known about the clinical burden of the obstructive subtype of HCM at a national 22 level, and how it may differ by New York Heart Association (NYHA) class. …”
Get full text

Constructing TheKeep.Ca With Thrivers of Cancer in Manitoba, Canada, in Support of Enhancing Patient Engagement: Protocol for a Pragmatic Multimethods Study by Maclean Thiessen, Kellie Jewitt, Raina Stromberg, Janelle Marie Lamontagne, Genevieve Richardson Tanguay, Annette Albo, Chantale Thurston, Diana E McMillan

“…A link allows visitors to register to be contacted about activities that match their demographics, cancer history, and activity preferences. …”
Get full text

The Assessment of the Supply of Calcium and Vitamin D in the Diet of Women Regularly Practicing Sport by Michał Wrzosek, Jakub Woźniak, Dorota Kozioł-Kaczorek, Dariusz Włodarek

“…It is important to educate women about the necessity to provide the body with proper calcium and vitamin D intake levels in a diet in order to avoid health problems resulting from the deficit of the nutrients.…”
Get full text

First‐in‐human orbital tumor surgery guided by near‐infrared II window fluorescence imaging: A feasibility study by Zeyu Zhang, Lishuang Guo, Lan Yao, Yueyue Li, Yan Hei, Qi Wang, Xiaoyi Wang, Rui Ma, Xinji Yang, Zhenhua Hu, Wei Wu

“…To establish the method of NIR‐II fluorescence imaging for orbital tumors, we developed a NIR‐II fluorescence imaging system and indocyanine green (ICG) served as the fluorescent contrast agent. Twenty‐two patients diagnosed with orbital tumors and scheduled for standard‐of‐care surgery were enrolled in this study. …”
Get full text

Diagnosis and Treatment of Peptic Ulcer in Adults (Clinical Guidelines of the Russian Gastroenterological Association, Russian Society of Colorectal Surgeons and the Russian Endosc... by V. T. Ivashkin, I. V. Maev, P. V. Tsar’kov, M. P. Korolev, D. N. Andreev, E. K. Baranskaya, S. G. Burkov, A. A. Derinov, S. K. Efetov, T. L. Lapina, P. V. Pavlov, S. S. Pirogov, A. V. Tkachev, A. S. Trukhmanov, E. D. Fedorov, A. A. Sheptulin

“…These clinical recommendations present modern ideas about the etiology and pathogenesis of peptic ulcer disease, its clinical manifestations, methods of laboratory and instrumental diagnostics and basic approaches to conservative and surgical treatment.…”
Get full text

Assessing the impacts of simulated ocean alkalinity enhancement on viability and growth of nearshore species of phytoplankton by J. L. Oberlander, M. E. Burke, C. A. London, H. L. MacIntyre

“…The analysis of prior studies indicates wide variability in the growth response to elevated pH within and between taxonomic groups, with about 50 % of species expected to not be impacted by the pH increase anticipated from unequilibrated mineral-based OAE. …”
Get full text