-
61
Anti-proliferative and photodynamic activities of Senna didymobotrya (Fresen.) leaf alkaloid-rich extracts against breast cancer cells
Published 2025-01-01“…Reactive oxygen species (ROS) levels in cell groups treated with the extracts and laser light were considerably higher than in experimental groups treated with only the extracts. …”
Get full text
Article -
62
-
63
Antifungal Activity of Gelatin-Tapioca Starch Film and Coating Containing Copper Nanoparticles against Colletotrichum gloeosporioides Causing Anthracnose
Published 2020-01-01“…Transmission electron microscopy (TEM) images and dynamic light scattering studies showed that the sizes of 90% of CuNPs were in 100–300 nm range. …”
Get full text
Article -
64
-
65
Development of a stable eukaryotic strain producing fully human monoclonal antibody on the basis of the human antibody against ectromelia virus
Published 2018-01-01“…Secondly, DNA fragments encoding the variable domains of the heavy and light chains of antibody against orthopoxvirus protein p35 were inserted into the pCDNA5/FRTDHFRCHCL cassette plasmid. …”
Get full text
Article -
66
Brucella suis ΔmapB outer membrane vesicles as an acellular vaccine against systemic and mucosal B. suis infection
Published 2025-01-01“…Currently, there are no available human or porcine vaccines to protect against B. suis infection, which is primarily acquired through the mucosa. …”
Get full text
Article -
67
-
68
Exploring Echinacea angustifolia for anti-viral compounds against Zika virus RNA-dependent RNA polymerase: a computational study
Published 2025-02-01“…These compounds showed strong hydrogen bond formation with crucial residues of the RDRP and presented favorable binding free energies. Our research sheds light on the viability of these E. angustifolia compounds as ZIKV RDRP inhibitors, laying a foundation for further experimental research in developing novel antiviral treatments against ZIKV infections.…”
Get full text
Article -
69
Mitophagy mediated by HIF-1α/FUNDC1 signaling in tubular cells protects against renal ischemia/reperfusion injury
Published 2024-12-01“…Accordingly, roxadustat may protect against RIRI-related AKI.…”
Get full text
Article -
70
Comprehensive Evaluation and Error-Component Analysis of Four Satellite-Based Precipitation Estimates against Gauged Rainfall over Mainland China
Published 2022-01-01“…To this end, the final run gauge-calibrated IMERG V06 (V06C) and uncalibrated IMERG V06 (V06UC) products are comprehensively evaluated here against 2088 precipitation gauges acquired between March 2014 and June 2018 over China. …”
Get full text
Article -
71
Development of a Recombinant Fusion Vaccine Candidate Against Lethal <i>Clostridium botulinum</i> Neurotoxin Types A and B
Published 2025-01-01“…BoNTs comprise three functional domains: a light-chain enzymatic domain (LC), a heavy-chain translocation domain (HC<sub>N</sub>), and a heavy-chain receptor-binding domain (HC<sub>C</sub>). …”
Get full text
Article -
72
-
73
Larvicidal Effects of Nanoliposomes Containing Clove and Cinnamon Essential Oils, Eugenol, and Cinnamaldehyde against the Main Malaria Vector, Anopheles stephensi Liston
Published 2022-01-01“…., eugenol and cinnamaldehyde, were first prepared; particle size and successful loading were investigated using DLS (Dynamic Light Scattering) and ATR-FTIR (Attenuated Total Reflection-Fourier Transform InfraRed) analysis. …”
Get full text
Article -
74
Protective Effect of High-Intensity Interval Training (HIIT) and Moderate-Intensity Continuous Training (MICT) against Vascular Dysfunction in Hyperglycemic Rats
Published 2022-01-01“…Under hyperglycemic conditions, both HIIT and MICT have a protective role against endothelial dysfunction.…”
Get full text
Article -
75
Development of a TCR-like antibody and chimeric antigen receptor against NY-ESO-1/HLA-A2 for cancer immunotherapy
Published 2022-03-01“…The generation of TCR-like antibody and its CAR-T cells provides the state-of-the-art platform and proof-of-concept validation to broaden the scope of target antigen recognition and sheds light on the development of novel therapeutics for cancer immunotherapy.…”
Get full text
Article -
76
-
77
A Cloud-Based Optimized Ensemble Model for Risk Prediction of Diabetic Progression—An Azure Machine Learning Perspective
Published 2025-01-01“…This study introduces an optimized Light Gradient-Boosting Machine (Light GBM) and K-Nearest Neighbour (KNN) based ensemble algorithm for predicting diabetic progression of Type 2 Diabetes, classifying it as high or low risk, using patient health parameters and serum measurements. …”
Get full text
Article -
78
Narrative temporality and Johannine symbolism
Published 2003-12-01“…In order to do this, this article takes up the subject of Johannine symbolism in the Fourth Gospel, especially the symbol of light, simply because it is not easy to understand. …”
Get full text
Article -
79
-
80
Design, synthesis and molecular modeling study of substituted indoline-2-ones and spiro[indole-heterocycles] with potential activity against Gram-positive bacteria
Published 2022-03-01“…Only 3-hydroxy-3-(2-(2,5-dimethylthiophen-3-yl)-2-oxoethyl)indolin-2-one (1b) was found as active as imipenem against S. aureus (MIC = 0.026 mmol L–1). In silico docking of the compounds in the binding sites of a homology modeled structure of S. aureus histidine kinase-Walk allowed us to shed light on the binding mode of these novel inhibitors. …”
Get full text
Article