FAP-targeted radioligand therapy with 68Ga/177Lu-DOTA-2P(FAPI)2 enhance immunogenicity and synergize with PD-L1 inhibitors for improved antitumor efficacy by Liang Zhao, Long Sun, Kaili Fu, Qin Lin, Xiaoyuan Chen, Qicong Luo, Hua Wu, Jianhao Chen, Yangfan Zhou, Yizhen Pang, Guoqiang Su, Haojun Chen

“…Furthermore, immunohistochemical staining and single-cell RNA sequencing were used to analyze changes in the tumor microenvironment (TME) and elucidate the underlying mechanisms of action of this combination therapy.Results Our findings indicated that FAP-targeting radiopharmaceuticals can induce DNA double-strand breaks and upregulate PD-L1 expression, with 177Lu-DOTA-2P(FAPI)2 proving to be more effective than 68Ga-DOTA-2P(FAPI)2. …”
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Application of PDCA cycle management model in home-based nursing of patients with indwelling gastric tubes (PDCA循环管理模式在留置胃管患者居家护理中的应用) by ZHANG Yue (张悦), ZHANG Jingzhi (张京芝)

“…Objective To use the Plan-Do-Check-Action(PDCA) cycle management model to reduce the number of nursing adverse events in home-based nursing of patients with indwelling gastric tubes. …”
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„Węgry to miejsce, w którym trzeba teraz być”. Węgierski postliberalizm i jego wpływ na amerykańskich konserwatystów by Nicholas Morieson

“…Zainteresowanie amerykańskich postliberałów Orbánem doprowadziło kilku z nich do złożenia mu wizyty, a także do podjęcia decyzji o zorganizowaniu konferencji Conservative Political Action Conference w 2022 r. w Budapeszcie. Niniejszy artykuł przygląda się powodom, dla których tak wielu amerykańskich konserwatystów zaczęło podziwiać postliberalny reżim Orbána na Węgrzech, czego się od niego nauczyli i czy amerykańscy konserwatywni działacze i politycy wprowadzają obecnie w życie nieliberalizm w stylu Orbána na amerykańskim gruncie. …”
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Management Control System and Financial Performance of Micro Finance Institutions in Central Region Uganda by Arthur, Sunday, Caleb, Tamwesigire, Caroline Masiko, Murezi, George Stanley, Kinyata, Godfrey, Barigye, Keneth, Nuwagira, Moses, Agaba

“…Failure by MFIs to monitor portfolio quality closely and take action when necessary and this has threatened the going concern of microfinance industry in Uganda. …”
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Investigating causal relationships between entrepreneurial education and sustainable employment generation in Islamic Azad Universities in Tehran by Sana Abdulali, Mohammad Naghi Imani GelepordesariI, Asghar Sharifi

“…The importance of using entrepreneurship has reached the point where some recognize it as one of the effective factors of production, such as working capital (apart from human power) and introduce it as an economic engine (Suryaman et al, 2023). Entrepreneurial action refers to the conceptualization and implementation of an idea, process, product, service or a new business. …”
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Faktor-Faktor yang Berhubungan dengan Kejadian Filariasis di Kabupaten Padang Pariaman Tahun 2010-2013 by Dhia Afra, Nora Abdiana Harminarti, Abdiana .

“…The data analysis was based on univariate and bivariate analysis equipped with chi-square test.The results of chi-square statistical test shows that there is significant correlation between age and filariasis prevalence with p value = 0.013, OR= 0.167, 95% CI= 0.043 – 0.652 but there was no correlation between gender, occupation (p value= 0.071, OR=3.800, 95% CI=0.938-15.398), breeding places, knowledge (p value= 1.000, OR=1.135, 95% CI=0.336 – 3.835),attitudes and action. The age is closely related to the occupation, so it needs intervention from health care workers how to protect while working, such as using a long-sleeved shirt, long pants and mosquito repellent. …”
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Pharmacokinetics and pharmacodynamics of ciprofol after continuous infusion in elderly patients by Xiaowen Guo, Yang Qiao, Sijie Yin, Fengqin Luo, Lingmei Yi, Jiajia Chen, Man Lu

“…Abstract Background Ciprofol, a novel intravenous anesthetic, which has primarily been used for the induction and maintenance of general anesthesia in adults, is characterized by rapid onset, short duration of action, and quick and smooth recovery. However, the pharmacokinetic characteristics of continuous infusions and the correlation between the plasma concentration and the bispectral index (BIS) in elderly patients are still unknown. …”
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Représentation et activité : deux concepts étroitement associés by Gérard Vergnaud

“…Ceci est vrai dans tous les domaines de connaissance, y compris les mathématiques ; et c’est encore plus vrai pour les enfants, qui ne sont guère capables d’exprimer les connaissances qu’ils utilisent dans l’action.Confrontés à des situations, les enfants peuvent saisir progressivement des entités relationnelles entre quantités et grandeurs, entre positions, figures et mouvements… Les relations partie-partie-tout, ou état-transformation-état, les propriétés d’isomorphisme dans les problèmes de proportion ne peuvent être réduites à des structures numériques ; ni être considérées seulement comme des entités linguistiques ou symboliques. …”
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Abordaje y manejo médico-quirúrgico del paciente herido por traumatismo taurino by A. Martínez-Hernández, G. Jara-Benedetti, C. Roig-Martí, C. Ordóñez-Urgiles, J.M. Laguna-Sastre

“…It is essential to establish particular initial care for this type of injury, specific therapeutic action and follow-up based on the medical-surgical management of the trauma patient in order to reduce the associated morbidity and mortality.…”
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Un programme d’éducation à l’environnement en RDC : la malle pédagogique « les grands singes et leur habitat », présentation des résultats d’une campagne de sensibilisation en pays... by Louis Ledo, Jean Christophe Bokika Ngawolo, Samy Mankoto, Richard Dumez, Sabrina Krief

“…Afin de mieux comprendre le contexte culturel du périmètre d’action de la malle en RDC et d’évaluer l’efficacité des messages de sensibilisations, des enquêtes mêlant questionnaires quantitatifs et entretiens semi-directifs ont été menées auprès de populations Batéké, du territoire de Bolobo (Province du Bandundu, RDC, février-juin 2011). …”
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De Rio 1992 à Marrakech 2016 : le Sud, acteur de la politique climatique by Michel Damian

“…Dans le second et le troisième point, nous proposons une relecture de la Convention de 1992 (en tant que produit d’un compromis avec et pour le Sud), ainsi que du protocole de Kyoto (qui a été, et demeure – avec la seconde période d’engagement de celui-ci jusqu’en 2020 – la pierre d’angle de l’action pour le Sud). Dans le quatrième point, nous montrons que l’Accord de Paris est le plus petit dénominateur commun – et le seul envisageable – pour la majorité des États du Nord et du Sud. …”
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[Translated article] Approach and management of patients injured by bullfighting trauma by A. Martínez-Hernández, G. Jara-Benedetti, C. Roig-Martí, C. Ordóñez-Urgiles, J.M. Laguna-Sastre

“…It is essential to establish particular initial care for this type of injury, specific therapeutic action and follow-up based on the medical–surgical management of the trauma patient in order to reduce the associated morbidity and mortality. …”
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Effects of Intrathecal Bupivacaine with Adjuvants Midazolam versus Magnesium Sulphate in Tibia Fibula Surgeries: A Randomised Clinical Study by Tejash H Sharma, Jagrati Jain, Aanal Sha, Dushyant Chavda, Dinesh K Chauhan

“…It also exhibits a muscle relaxant effect via its action on the glycine receptors in the spinal cord. …”
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Plaider la « bonne gouvernance sécuritaire » au Maroc : Domestiquer les savoirs de réforme en régime de contrainte consensuelle by Irene Lizzola

“…In this register, the consensus is built around the reciprocal obligation to validate a legalist and managerial reformist discourse, strongly internationalized and deconflictualizing the issues, which unites the parties, as well as the mutual acceptance of the logics which accompany partnership selectivity governing the participation of associative and transnational actors in the “co-production” of public action. Here, the different actors play with these constraint factors, from the moment when each party benefits from the participation in the partnership dynamic. …”
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SEED (Stoke Disease Early Detection Application) - Rancang Bangun Aplikasi Mobile Berbasis Android untuk Mendiagnosis Gejala Dini Penyakit Stroke Menggunakan K-Nearest Neighbor (K-... by Dedin Anike Putra, Muhammad Dimas Setiawan Sanapiah, Azifatul Istna Hanifah, Tri Afirianto

“…Data from Syaiful Anwar Hospital (RSSA) Malang City shows that 30% of stroke patient's age is among 18-30 years old. Preventif action needs to be done for reducing the risk level of stroke. …”
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Structural Model of Factors Affecting the Use of Organic Fertilizers by Rice Farmers during Rice (Oryza sativa) Cultivation in Dezful County by Zahra Eskanadari, Moslem Saavri, Masoud Yazdanpanah

“…The form and content validity of the questionnaire was confirmed by experts' opinion and its reliability was confirmed through Cronbach's alpha and composite reliabilityResults and DiscussionThe results of the structural equation modeling research showed that the variables of self-efficacy (ƛ=0.257; P=0.000), action guide (ƛ=0.222; P=0.000), perceived intensity (ƛ=0.121; P=0.035) and perceived sensitivity (ƛ= 0.100; P= 0.046) and perceived benefits (ƛ= 0.319; P= 0.000) have a positive and significant effect on the use of organic fertilizers among rice farmers in Dezful County. …”
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Entre espaces domestiques et « espaces domestiqués » : « L’autonomisation intime » des étudiantes en Turquie by Tuğba Gökduman

“…In this article, “intimate autonomy” refers to the idea that the individual is defined as the “author of their action” in their private and sexual life. Young unmarried women, often viewed as potential sexual victims or corrupters of the moral order, are subject to surveillance in the name of “protection.” …”
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Call for Papers - Advancing Astropharmacy and Sports Pharmacy by Ashley Anderson, Ahmer Raza, Shireen Aziz, Misbah Noreen

“…She is actively working on addressing the challenges of medication stability in space and investigating the physiological effects of the space environment on drug metabolism and action. Misbah is also contributing to the advancement of the emerging field of Astropharmacy, collaborating with global experts to explore innovative pharmaceutical practices and regulatory frameworks for space missions. …”
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Modalities for the treatment of primary open-angle glaucoma by Zh.G. Oganezova, S.V. Simonova

“…When switching to brimonidine, greater IOP-lowering effect can be explained by its dual action, i.e., a decrease in aqueous flow and an increase in uveoscleral outflow. …”
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Implementasi Algoritma Naïve Bayes untuk Mendeteksi Resiko Tinggi Diabetes Melitus Pada Ibu Hamil (Studi Kasus : Puskesmas Kabupaten Malang) by Fatmawati Fatmawati, Satrio Agung Wicaksono, Satrio Hadi Wijoyo

“…In addition, recommendations from the system can support a midwife's decision making in taking action to pregnant women. The highest accuracy value is found in the 4th test of 82,4324% and the lowest accuracy value in the 2nd test is 75%. …”
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