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  1. 12301
  2. 12302

    LGR4 is essential for maintaining β-cell homeostasis through suppression of RANK by Joanna Filipowska, Zelda Cisneros, Sneha S. Varghese, Nancy Leon-Rivera, Peng Wang, Randy Kang, Geming Lu, Yate-Ching Yuan, Hung-Ping Shih, Supriyo Bhattacharya, Sangeeta Dhawan, Adolfo Garcia-Ocaña, Nagesha Guthalu Kondegowda, Rupangi C. Vasavada

    Published 2025-02-01
    “…To determine the role of LGR4 we employed in vitro Lgr4 loss and gain of function in primary rodent and human β-cells and examined its mechanism of action in the rodent INS1 cell line. Using Lgr4fl/fl and Lgr4fl/fl/Rankfl/fl × Ins1-Cre mice we generated β-cell-specific conditional knockout (cko) mice to test the role of LGR4 and its interaction with RANK in vivo under basal and stress-induced conditions. …”
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  3. 12303

    Quand la littérature formatait les vies by José-Luis Diaz

    Published 2015-02-01
    “…À partir de Mme de Staël et tout au long du xixe siècle, la présente étude suit le déploiement de cette autre sociologie qui a eu à cœur d’explorer la réciproque de la formule bonaldienne (la littérature comme « expression de la société »)Si l’on pense alors que la littérature a une influence sociale, c’est qu’il y a eu, au cours de la période romantique, une révolution majeure affectant la sphère d’influence de la littérature : son action ne s’exerce plus seulement dans le monde des idées, mais elle passe dans la sphère de la vie pratique. …”
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  4. 12304

    UPAYA MENINGKATKAN MOTIVASI DAN HASIL BELAJAR SISWA DENGAN MODEL DISCOVERY LEARNING BERBANTUAN VIRTUAL LABORATORY by Faiz Brikinzky Adyan, Andik Purwanto, Nirwana Nirwana

    Published 2019-12-01
    “…This research was a classroom action research. The subject of research was the whole student of XI MIPA A SMAN 2 city of Bengkulu that amounted 32 student. …”
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  5. 12305

    Application of PDCA cycle management to improve the nursing quality and work enthusiasm of nursing staff in the Geriatric Department (运用PDCA循环管理法提升老年病科护理人员护理质量和工作积极性)... by LIU Yang (刘洋)

    Published 2024-03-01
    “…Objective To investigate the effect of Plan-Do-Check-Action(PDCA) cycle management on improving the nursing quality and work enthusiasm of nursing staff in the Geriatric Department. …”
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  6. 12306

    Experimental Investigation on Shear Strength between Ultra-High-Performance Concrete and Normal Concrete Substrates by Xinghong Jiang, Hengxiang Song, Ke Li, Jing Qiang, Jing Tian

    Published 2023-01-01
    “…When the number of keyways is equivalent to the roughness index, the relationship between the shear strength and the roughness is as follows: fs=1.664+3.030Rz. Under the action of keyway, the interface slip of UHPC-NC can be simplified into four stages: the interface slip stage, the keyway strengthening stage, the shear yield stage, and the specimen failure stage. …”
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  7. 12307

    KULTŪRINIO IR SIMBOLINIO KAPITALO GAMYBA: "DISNEY" FENOMENAS by Gintautas Mažeikis

    Published 2003-01-01
    “…Historical analyses show  how  ideologies,  conceptual  paradigms,  action models developed by Disney met wishes of the masses, implemented modern multiculturalism, diversification and supported social fragmentation. …”
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  8. 12308

    Universality of universal health coverage: A scoping review. by Aklilu Endalamaw, Charles F Gilks, Fentie Ambaw, Yibeltal Assefa

    Published 2022-01-01
    “…The study implies that urgent action on the identified policy, health system and cross-cutting barriers is required to achieve UHC.…”
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  9. 12309

    Disorders of the central nervous system cognitive and mnestic functions in genetic arterial hypertension and with the use of beta-blockers of different generations by A. O. Svitlytskyi, A. A. Yehorov, O. V. Melnikova, T. A. Hrekova

    Published 2024-09-01
    “…Drug correction of arterial hypertension with hypertril (a β-blocker of the latest generation with NO-mimetic action) has a highly effective effect on the development of conditioned-reflex skills and the ability to learn that indicates a reduction in cognitive deficits in SHR with essential arterial hypertension.…”
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  10. 12310

    Multiple Mini Interviews vs Traditional Interviews: Investigating Racial and Socioeconomic Differences in Interview Processes by Banks PW, Hagedorn II JC, Soybel A, Coleman DM, Rivera G, Bhardwaj N

    Published 2025-02-01
    “…President & Fellows of Harvard College, which ended race-conscious admissions, or affirmative action, and upheld holistic admissions practices, encouraged medical school admissions committee to reevaluate their approach to admissions.Methods: Data from six admissions cycles (2018– 2022), totaling 5799 interviewees, were analyzed to assess potential biases and the effectiveness of the admissions process. …”
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  11. 12311

    Farmer perception of impacts of fall armyworm (Spodoptera frugiperda J.E. Smith) and transferability of its management practices in Uganda by Andrew Kalyebi, Michael H. Otim, Tom Walsh, Wee Tek Tay

    Published 2023-04-01
    “…A small number of farmers (ca. 4%) in both districts reportedly took no intentional action against FAW. Conclusions The farmers believe they can manage FAW if they have the appropriate and efficacious chemical insecticides as they are able to correctly apply them and follow recommended procedures. …”
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  12. 12312

    Computational and theoretical studies of nodal joints in monolithic buildings by T. A. Belash, A. V. Kuznetsov

    Published 2024-02-01
    “…The results of numerical simulation showed that under the action of negative outdoor temperatures, the greatest stresses occur at the junctions of perforations with keys and exceed the standard values of the calculated stress by 1.4 times. …”
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  13. 12313

    The effect of groundwater depth on topsoil organic matter mineralization during a simulated dry summer in northwestern Europe by A. Françoys, A. Françoys, O. Mendoza, J. Hu, P. Boeckx, W. Cornelis, S. De Neve, S. Sleutel

    Published 2025-01-01
    “…We examined (1) upward moisture flow by capillary action along the soil profile, specifically into the top 20 cm of soil, and (2) the effect of the GWT on the decomposition of an added <span class="inline-formula"><sup>13</sup>C</span>-enriched substrate (ryegrass) over a period of 10 weeks, with limited wetting events representing a dry summer. …”
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  14. 12314

    EPIGENETICS TODAY AND TOMORROW by B. F. Vanyushin

    Published 2015-01-01
    “…Use of specific small RNAs in the therapy of cancer and other diseases appears to be particularly promising, especially in connection with directed inhibition of transcription of genes responsible for cell malignization and metastasis. The therapeutic action of many known small biologically active peptides seems to be expressed mainly at the epigenetic level. …”
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  15. 12315

    Factors Influencing Telemedicine Adoption Among Health Care Professionals: Qualitative Interview Study by Fiona Schürmann, Daniel Westmattelmann, Gerhard Schewe

    Published 2025-01-01
    “…It advances theory by decomposing trust referents and transparency into actionable subdimensions and emphasizing context-specific variables. …”
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  16. 12316

    Platelet-rich plasma combined with gypenosides for the treatment of psoriasis-like inflammation in mice by LI Dandan, WANG Bing, GE Yu, CHENG Hong, LI Mengxue, WANG Zhicheng, XIA Rong

    Published 2024-12-01
    “…[Objective] To investigate the therapeutic effect of platelet-rich plasma (PRP) subcutaneous injection combined with gypenosides (GPs) oral administration on BALB/c mouse psoriatic inflammation and explore its mechanism of action. [Methods] The 6-8 week-old female SPF BALB/c mice were randomly divided into five groups: control, model, PRP, GPs and PRP+GPs group, with 5 mice in each group. …”
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  17. 12317
  18. 12318

    Ethnic and racial discrimination in maternal health care in Mexico: a neglected challenge in the search for universal health coverage by Edson Serván-Mori, Sergio Meneses-Navarro, Rocío García-Díaz, Diego Cerecero-García, David Contreras-Loya, Octavio Gómez-Dantés, Arachu Castro

    Published 2025-01-01
    “…Conclusions Despite modest health policy successes, the ethnic gap in ECMH remains unchanged, indicating insufficient action against inequity-producing structures. Ethnic and racial discrimination persists, exacerbated during the pandemic and coinciding with the government’s cancellation of targeted social programs and public health insurance focused on the poorest populations, including Indigenous peoples. …”
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  19. 12319

    Identification and Mass Spectrometric Fragmentation Pathways of Chemical Components in the Traditional Chinese Medicine Formula of Jiuwei Decoction by Jia-yu ZHAO, Yue-guang LYU, Tong XIN, Qian-qian GUO, Wen-ying ZHANG, Jin-hong LI, Hong-yu XUE, Qiang MA

    Published 2025-01-01
    “…This study provides a precise identification of the chemical constituents in Jiuwei decoction, thus furnishing a robust scientific foundation for further exploration into its pharmacological effects and mechanisms of action. Moreover, this study serves as an invaluable reference for the analysis of the chemical composition of TCM formulations. …”
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  20. 12320

    Exploring the Feasibility of a 5-Week mHealth Intervention to Enhance Physical Activity and an Active, Healthy Lifestyle in Community-Dwelling Older Adults: Mixed Methods Study by Kim Daniels, Sharona Vonck, Jolien Robijns, Kirsten Quadflieg, Jochen Bergs, Annemie Spooren, Dominique Hansen, Bruno Bonnechère

    Published 2025-01-01
    “…ObjectiveThe main objective of this feasibility study was to assess the feasibility, usability, and acceptability of the More In Action (MIA) app, designed to promote PA among older adults. …”
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