Exploring the Mechanism of Canmei Formula in Preventing and Treating Recurrence of Colorectal Adenoma Based on Data Mining and Algorithm Prediction by Xiaoling Fu, Yimin Xu, Xinyue Han, Xiangying Lin, Jingnan Wang, Guanhong Li, Xiaochen Fu, Min Zhang

“…Canmei Formula (CMF) has shown promising results in the prevention and treatment, however, it lacks effective clinical data support and its mechanism of action is not fully elucidated. Objective The aim of this study is to evaluate the clinical efficacy and safety of CMF in preventing and treating CRA, and to explore its effective chemical components and pharmacological mechanisms. …”
Get full text

Ginsenoside Rd protects against acute liver injury by regulating the autophagy NLRP3 inflammasome pathway by Xiaomei Zhong, Yibin Sun, Yanxiang Lin, Shan Deng, Huan Wang, Xian Zhou, Jinjian Lu, Yanfang Zheng, Ruoyin Luo, Mingqing Huang, Jianyuan Song

“…However, its hepatic protective effect against acute liver injury and related mechanistic action remain unexplored. To investigate the protective effect of Rd against thioacetamide (TAA)-induced acute liver injury and assess its underlying regulatory mechanisms related to autophagy and inflammation. …”
Get full text

Biosynthesis and activity of Zn-MnO nanocomposite in vitro with molecular docking studies against multidrug resistance bacteria and inflammatory activators by Samy Selim, Tarek M. Abdelghany, Mohammed S. Almuhayawi, Mohammed K. Nagshabandi, Muyassar K. Tarabulsi, Mohammed Yagoub Mohammed Elamir, Asmaa A. Alharbi, Soad K. Al Jaouni

“…The minimum binding energy was utilized to estimate the receptor’s binding site with NPs, providing additional understanding of the ways of action. Anti-inflammatory activity of Zn-MnO nanocomposites via cyclooxygenase-1 and cyclooxygenase-2 enzymes inhibition was documented with IC50 doses of 20.81 ± 0.68 µg/mL and 35.87 ± 1.35 µg/mL, respectively. …”
Get full text

Construct validity and responsiveness of clinical upper limb measures and sensor-based arm use within the first year after stroke: a longitudinal cohort study by Johannes Pohl, Geert Verheyden, Jeremia Philipp Oskar Held, Andreas Ruediger Luft, Chris Easthope Awai, Janne Marieke Veerbeek

“…Using clinical measures, upper limb motor function (Fugl-Meyer Assessment), capacity (Action Research Arm Test, Box & Block Test), and perceived performance (14-item Motor Activity Log) were assessed. …”
Get full text

Réprimer par le droit : L’intervention de la Brigade nationale de police judicaire dans les procès du Hirak El-Rif by Mariam Benalioua

“…The argument I defend consists in showing how the BNPJ has changed its methods and strategy of repression, from a brigade whose mission was to dismantle clandestine left-wing political organizations through torture and secret detention, with the sole aim of gathering information leading to the location and tracking down of political activists in order to make them disappear, to a Brigade whose strategy of repression involved judicial action, conducting interrogations and drawing up reports aimed at collecting legal evidence that could be used during trials. …”
Get full text

Interstep Variations of Stairways and Associations of High-Contrast Striping and Fall-Related Events: Observational Study by Sara A Harper, Chayston Brown, Shandon L Poulsen, Tyson S Barrett, Christopher J Dakin

“…Possibly, perception and action elicited through the horizontal-vertical illusion (striping) may have a positive impact on the incidence of fall-related events in the presence of high interstep riser height and depth variation. …”
Get full text

Innovative Model of Socio-Professional Development of a Student’s Personality by E. F. Zeer, V. S. Tretyakova, M. V. Zinnatova

“…The mechanism of the model implementation is to build an individual student professional perspective aimed at practical action in order to improve the level of qualification, ability to work, enrichment of professional and personal qualities and behavioural patterns.Scientific novelty of the present research consists in the formation of interdisciplinary scientific knowledge (at the intersection of psychology, pedagogy, philosophy, occupational studies) on the methodology of the modelling, organisation and content of professional education taking into account modern challenges and demands of the digital economy. …”
Get full text

Maximizing the potential of water buffalo milkability: best practices and lessons learned by Carlo Boselli, Antonio Borghese

“…The milk stored in the buffalo udder can be divided into two fractions: the cisternal fraction, which has already been transferred from the alveoli to the cistern during the interval between milkings and is immediately available, and the alveolar fraction, which can only be removed from the udder by the action of oxytocin. In buffalo milking management, the milking machine is a critical point, and the characteristics of the milking vacuum and the pulsation rate are closely related to milk flow observations; in Italy, the most commonly used vacuum levels are 44–46 kPa (range 40–53 kPa). …”
Get full text

Immune Modulation Effect of Administration of Rice Bran Extract with Increased Solubility Fermented by <i>Lentinus edodes</i> UBC-V88 in Cyclophosphamide-Treated Mice Model by Gi-Jung Kim, Yelim Jang, Ji-Yoon Hong, Kyoung-Tae Kwon, Dae-Weon Kim, Dae-Jung Kang, Sung-Joo Hwang, Jung-Yun Lee, Emmanouil Apostolidis, Young-In Kwon

“…In this study, the immunomodulatory effect and mechanism of action of rice bran extract fermented by <i>Lentinus edodes</i> was investigated. …”
Get full text

PENINGKATAN KEMAMPUAN GENERIK FISIKA DAN PEMAHAMAN KONSEP DALAM PEMBELAJARAN GUIDED DISCOVERY MELALUI EKSPERIMEN PADA ALAT-ALAT OPTIK by Partogi Nainggolan, Nyoman Rohadi, Eko Risdianto

“…This research was a classroom action research conducted in three cycles. Subjects in this study were all students of class XI MIA 2 that consists of 32 people consisting of 14 male students and 18 female students. …”
Get full text

The Mechanisms of Guaranteeing the Right to Clean Air in Iran and International Documents by Fatemeh Hamidi, Maryam Afshari, Ali Mashhadi

“…Due to the negative effects of air pollution on the health of citizens and the country's economy, urgent action to untie the existing knots over the implementation of the Clean Air Act is necessary and there must be a serious will in this regard.…”
Get full text

Proximity or Directional Model of Voting for the Turkish Voter? by Murat İnan, Gül Arıkan Akdağ

“…Our research analyzes Comparative Study of Electoral Systems (CSES) data for voters of the four major political parties in Türkiye, the Justice and Development Party (JDP), the Republican People’s Party (RPP), the National Action Party (NAP), and the People’s Democratic Party (PDP). …”
Get full text

Development of an Alternative Protocol to Study Muscle Fatigue by Daniela A. Alambarrio, Benjamin K. Morris, R. Benjamin Davis, Emily B. Grabarczyk, Kari K. Turner, John M. Gonzalez

“…Muscle workload during EMS was measured with EMG using median power frequency (<b>MdPF</b>) and root mean square (<b>RMS</b>) as indicators of action potential velocity and muscle fiber recruitment. …”
Get full text

Study of anti-inflammatory, antioxidant, antimicrobial and mineralizing effects of an N-isopropenylimidazole zinc metal complex derivative in experimental endodontic-periodontal le... by Pavel A. Galenko-Yaroshevsky, Ivan I. Pavlyuchenko, Olga V. Shelemekh, Boris A. Trofimov, Lidiya N. Parshina, Viktor L. Popkov, Svetlana A. Demyanenko, Oleg V. Tsymbalov, Andrey V. Zadorozhniy, Anait V. Zelenskaya, Irina B. Nektarevskaya, Alina V. Sergeeva, Nikolay E. Korovaykin, Svetlana A. Lebedeva

“…In the pulp in EPL, Pilim-1 and, to a greater extent, the combination Pilim-1 + M-D in a more pronounced way than M-D have anti-inflammatory, antimicrobial (reduce a microbial content level) and mineralizing effects. In the therapeutic action mechanisms of Pilim-1 and, especially, the combination Pilim-1 + M-D in EPL conditions, their ability to have an antihypoxic effect and an inhibitory effect on cyclooxygenase and 5-lipoxygenase is likely to play a very important role, in addition to their identified effect on the examined metabolic processes. …”
Get full text

Wunsch nach Mitgestaltung als Berufswahlmotiv – eine qualitative Analyse zur Berufswahl von Studierenden der Sonderpädagogik by Ralf Schieferdecker, Veronika Dumbacher, Teresa Sansour, Gregor Frirdich

“…It shows that the selected degree programme is associated with the idea of autonomy of action in the special education profession, which can be located on the three levels of society, the education system and interaction with pupils. …”
Get full text

Diabetes distress among immigrants of south Asian descent living in New York City: baseline results from the DREAM randomized control trial by Farhan Mohsin, Laura Wyatt, Hayley Belli, Shahmir Ali, Deborah Onakomaiya, Supriya Misra, Yousra Yusuf, Shinu Mammen, Jennifer Zanowiak, Sarah Hussain, Haroon Zafar, Sahnah Lim, Nadia Islam, Naheed Ahmed

“…Methods Baseline data was collected from the Diabetes Research, Education, and Action for Minorities (DREAM) Initiative, an intervention designed to reduce hemoglobin A1c (HbA1c) among South Asian individuals with uncontrolled T2D at primary care practices in NYC. …”
Get full text

UPAYA MENINGKATKAN MOTIVASI BELAJAR DAN KEMAMPUAN PEMECAHAN MASALAH SISWA MELALUI MODEL PROBLEM BASED LEARNING BERBANTU ALAT PERAGA KONSEP GERAK LURUS by Budi Santoso, Desy Hanisa Putri, Rosane Medriati

“…This research was a classroom action research on the concept of straight motion carried out in three cycles. …”
Get full text

Clinical Observation on Children with Peripheral Facial Paralysis Treated by Acupoint Injection of Mouse Nerve Growth Factor Combined with Acupuncture by Mian KONG, Wei LIU, Zhihua YU, Ming FANG

“…After three weeks of treatment, the clinical efficacy, H-B facial nerve function grading, average effective time, Portmann score, compound muscle action potential (CMAP), nerve conduction velocity, blink reflex (BR) latency and adverse reactions were compared between the two groups.Results:Before treatment, there was no significant difference in H-B facial nerve function grading between the two groups (<italic>P</italic>&gt; 0.05). …”
Get full text

OSSERVARE E INSEGNARE L’ESPRESSIONE DELL’APPROSSIMAZIONE NELL’ITALIANO PARLATO ACCADEMICO: L’USO DI LISTE ED ECCETERA by Elisa Fiorenza

“…These functions support the didactic action, as they enable the gradual construction of meanings and convey content in a flexible manner with respect to situational needs. …”
Get full text

EDENT1FI Master Protocol for screening of presymptomatic early-stage type 1 diabetes in children and adolescents by Melanie Gündert, Anette-Gabriele Ziegler, Peter Achenbach, Olga Kordonouri, Agnieszka Szypowska, Ezio Bonifacio, Parth Narendran, Christiane Winkler, R Ribeiro, Sandra Hummel, Przemysława Jarosz-Chobot, Emanuele Bosi, R Lahesmaa, K Casteels, M Peakman, P Jarosz-Chobot, O Kordonouri, Chantal Mathieu, Vito Lampasona, J F Raposo, H Hyöty, F Pociot, João Filipe Raposo, R Berner, R Bergholdt, E Bonifacio, Flemming Pociot, B Petersen, J Van Rampelbergh, L Overbergh, B Van der Schueren, V Lampasona, C Winkler, R Coelho, O Cohen, C Mathieu, E Bosi, Stefanie Arnolds, Lut Overbergh, Zdenek Sumnik, A Koralova, G Sebastiani, Luisa Hoffmann, Mirjam Kohls, Regine Bergholdt, Bianca K Hoefelschweiger, Jurgen Vercauteren, P Gillard, J Vercauteren, A G Ziegler, P Achenbach, F Haupt, S Hummel, T Pieber, J Mader, S Moitzi, S Del Prato, B Torbeyns, Z Sumnik, O Cinek, V Neuman, B Berka, J Antvorskov, J H Klaebel, J E Laiho, F Reschke, T von dem Berge, A Hommel, A Loff, G Gemulla, N Zubizarreta, L Piemonti, F Dotta, A Szypowska, K Karczewski, E Niemoeller, M Baccara-Dinet, K Fogh, M I Buompensiere, C Hurtado del Pozo, E Latres, G Agiostratidou

“…These include a reduced risk of diabetic ketoacidosis (DKA) at the clinical manifestation of the disease and a significant reduction in clinical symptoms. The European action for the Diagnosis of Early Non-clinical Type 1 diabetes For disease Interception (EDENT1FI) represents a pioneering effort to advance early detection of type 1 diabetes through public health screening. …”
Get full text