The Effect of Virtual Reality on Motor Anticipation and Hand Function in Patients with Subacute Stroke: A Randomized Trial on Movement-Related Potential by Ling Chen, Yi Chen, Wen Bin Fu, Dong Feng Huang, Wai Leung Ambrose Lo

“…Outcome measures of the contingent negative variation (CNV) latency and amplitude, EMG reaction time, Upper Limb Fugl-Meyer Assessment (UL-FMA), Action Research Arm Test (ARAT), and National Institutes of Health Stroke Scale (NIHSS) were recorded pre- and postintervention. …”
Get full text

Experimental Study on Fe3O4 Nanoparticle-Assisted Microwave Enhancing Heavy Oil by Teng Lu, Faqiang Dang, Haitao Wang, Qingmin Zhao, Zhengxiao Xu

“…Obtaining the mechanism of nanoparticle-assisted microwave to enhance oil recovery, one of which is that nanoparticles improve the wave absorption and heating capacity of heavy oil and increase the heating speed of heavy oil; the second is that the nanoparticles form local high temperature under the action of microwave, which catalyzes the hydrocracking reaction between the heavy components in the heavy oil and the hydrogen donor, upgrading and reducing the viscosity of the heavy oil, and accelerating the production of heavy oil.…”
Get full text

Assessing the feasibility of using publicly available data sources to identify healthcare data discrepancies and enhance service delivery: a retrospective cross-sectional study of... by Sheila Leatherman, Matthew Neilson, Alix Boisson-Walsh, Jack Lewis

“…Missing data existed for two specific metrics in all four countries, particularly within the improving clinical care domain.Conclusion The results are a clarion call for advancing efforts to develop standardised, publicly available, routinely collected and validated data sets to measure and publicly report LHDIS countries’ state of quality to marshal global attention and action in pursuit of more significant health equity.…”
Get full text

Pharmacological Mechanism of Zuojin Pill for Gastroesophageal Reflux Disease: A Network Pharmacology Study by Mi Lv, Jinke Huang, Jiayan Hu, Wenxi Yu, Ping Liu, Kunli Zhang, Fengyun Wang

“…Although Zuojin Pill (ZJP) is widely used in China as a traditional prescription to treat gastroesophageal reflux disease (GERD), its exact mechanism of action is still unknown. Therefore, we employed network pharmacology (NP), molecular docking (MD), and molecular dynamics simulation (MDS) to investigate the pharmacological mechanisms of ZJP against GERD. …”
Get full text

Phthalate exposure induces microRNA-5010/Nrf2-EGR1/GDF15 signaling expression in prostate cancer by Yuh-Shyan Tsai, Yeong-Chin Jou, Ian Seng Cheong, Hsiu-Ting Tung, Lin-Nei Hsu, Hsin-Tzu Tsai, Tzong-Shin Tzai

“…However, its role and action mechanism in prostate cancer remain unclear. …”
Get full text

Supply chain performance in the age of Industry 4.0 by Tahsina Khan, Md Mehedi Hasan Emon

“…Practical implications: The study provides actionable insights for manufacturing firms in developing economies on leveraging Industry 4.0 technologies to enhance supply chain performance. …”
Get full text

Design and maintenance of medical oxygen concentrators in Sub-Saharan Africa: a systematic review by Nahimiya Husen Ibrahim, James Wallace, Davide Piaggio, Leandro Pecchia

“…This review aims to systematically identify and assess the literature on OC design adaptations, maintenance challenges, and knowledge gaps in SSA, providing actionable recommendations to inform innovative and context-sensitive solutions to improve healthcare delivery in the region. …”
Get full text

Da-Chuan-Xiong Decoction Ameliorates Sodium Sensitivity and Plasma Norepinephrine via Attenuation of Brain Oxidative Stress in the DOCA-Salt Hypertensive Rats by Qi Zhang, Hao Li, Shan Zhao, Fangfang Li, Yingying Tan

“…These findings indicate that the depressor action and sympathetic inhibition of DCXD on salt-sensitive hypertension may be by ameliorating brain sodium sensitivity, modulating ENaC function, and inhibiting the expression of ENaC and NADPH oxidase in the hypothalamic paraventricular nucleus.…”
Get full text

Bailing Out the Protester by Alireza Nourani-Dargiri

“…This Article discusses how cash bail dissuades First Amendment expression by compounding existing consequences created by government action that also curtails lawful protests. Furthermore, the disparate rates at which protesters of color are arrested and later imposed bail raises an equal protection concern, deterring people of color from expressing constitutional rights. …”
Get full text

The Identification and synthesis of metabolites of 4-(5-methyl-1,3,4-oxadiazole-2-yl)-benzenesulfonamide by Alexander L. Khokhlov, Ilya I. Yaichkov, Anton A. Shetnev, Valeria A. Panova, Julia A. Efimova, Sergey A. Ivanovskiy, Mikhail K. Korsakov, Nikita N. Volkhin, Sergey S. Petukhov

“…Introduction: 4-(5-methyl-1,3,4-oxadiazole-2-yl)-benzenesulfonamide is a new selective type II carbonic anhydrase inhibitor with local action through instillation into the eyes. For a complete pharmacokinetic study of this drug, it is necessary to detect and synthesize its metabolites for their systemic exposure evaluation. …”
Get full text

Trimethylamine-N-Oxide Promotes High-Glucose-Induced Dysfunction and NLRP3 Inflammasome Activation in Retinal Microvascular Endothelial Cells by Lidan Xue, Lili Huang, Yajing Tian, Xin Cao, Yu Song

“…ZO-1 expression decreased remarkably with the combined action of TMAO and a high glucose compared to either treatment alone. …”
Get full text

Network relationship between cognitive function and quality of life in community-dwelling older adults: an observational study from Beijing by Yitian Ye, Yichun Zhang, Jiaju Ren, Yanbo Zhu, Yanbo Zhu

“…ObjectiveThis observational study aims to comprehensively explore the network relationship and mechanism of action between cognitive function and quality of life among community-dwelling older adults aged 60 and above in Beijing.MethodsThe research encompassed a cohort of 323 older adults individuals residing in the community in Beijing. …”
Get full text

Autonomic Nervous System Activity before Atrial Fibrillation Onset as Assessed by Heart Rate Variability by Jean-Marie Grégoire, Cédric Gilon, François Marelli, Pascal Godart, Hugues Bersini, Stéphane Carlier

“…However, despite its ability to influence the autonomic nervous system (ANS), the exact mechanism of action remains unclear. The activity of the ANS via the intracardiac nervous system (ICNS) can be inferred from heart rate variability (HRV). …”
Get full text

Long-term postoperative regional analgesia of the lower third of the face in patients with tumors of the oral cavity by A.O. Kushta, S.M. Shuvalov

“…On the day 10 of using a long-term postoperative regional analgesia, a positive trend towards a reduction in pain syndrome was observed (2.0±0.63), in contrast to drugs of general action (p<0.05). Over the course of a long-term postoperative regional analgesia it was noted that analgesic effect increases from blockade to blockade. …”
Get full text

Involvement of Neuropeptide Y within Paraventricular Nucleus in Electroacupuncture Inhibiting Sympathetic Activities in Hypertensive Rats by Qi Zhang, Yingying Tan, Xin Wen, Fangfang Li

“…This study aimed to assess the hypothesis that EA treatment exerts a hypotensive action via suppressing sympathetic activities and modulating neuropeptide Y (NPY) function within the paraventricular nucleus (PVN) of hypertensive rats. …”
Get full text

Copper Does Not Induce Tenogenic Differentiation but Promotes Migration and Increases Lysyl Oxidase Activity in Adipose-Derived Mesenchymal Stromal Cells by Marta Milewska, Anna Burdzińska, Katarzyna Zielniok, Katarzyna Siennicka, Sławomir Struzik, Piotr Zielenkiewicz, Leszek Pączek

“…Moreover, a high level of CuSO4 stimulated the action of intracellular superoxide dysmutase. The hASC secretion profile after a 5-day exposure to 50 μM cupric sulfate differed from that of untreated cells and was similar to the secretion profile of human tenocytes. …”
Get full text

The burden and outcomes of firearm injuries at two district-level emergency centres in Cape Town, South Africa: A descriptive analysis by L Bush, C Hendrikse, C Van Koningsbruggen, K Evans

“…Data from this study aid our understanding of the prevalence and burden of firearm injuries at district level emergency centres, and multisectoral action, supported by evidence-based primary and secondary preventive strategies, is required to reduce the burden of firearm injuries, and mitigate their effects. …”
Get full text

Cloud-edge hybrid deep learning framework for scalable IoT resource optimization by Umesh Kumar Lilhore, Sarita Simaiya, Yogesh Kumar Sharma, Anjani Kumar Rai, S. M. Padmaja, Khan Vajid Nabilal, Vimal Kumar, Roobaea Alroobaea, Hamed Alsufyani

“…PPO enhances policies in continuous action spaces to guarantee reliable performance in real-time, dynamic IoT settings. …”
Get full text

Coal‐wall spalling prevention mechanism using advance‐grooving pressure relief in the large‐mining‐height working face of a shallow coal seam by Wang Hongwei, Feng Li, Zhao Zhouyan, Li Yanjun, Cao Peipei, Jiao Jianqiang, Jiang Baolin, Liu Yong

“…At the same time, the strain energy and gravitational potential energy of roof cutting instability are released to form a dynamic load. Under the action of dynamic and static load, the plastic failure dissipation power of the coal wall is greater than the critical power, and the coal wall spalling occurs. …”
Get full text

Improving the Generalizability and Robustness of Large-Scale Traffic Signal Control by Tianyu Shi, Francois-Xavier Devailly, Denis Larocque, Laurent Charlin

“…In particular, we use implicit quantile networks (IQN) to model the state-action return distribution with quantile regression. …”
Get full text