Efficacy and compatibility mechanism of bear bile powder in Shexiang Tongxin dropping pills for acute myocardial infarction treatment by Yu Luo, Fangmin Zhang, Lidan Zhu, Jianfeng Ye, Hong-ye Pan, Xiaoyan Lu, Xiaohui Fan

“…The efficacy and compatibility mechanisms of action of BBP in STDP against cardiovascular diseases remain unclear. …”
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The immunoregulatory effects of scoparone on immune-mediated inflammatory diseases by Feifei Qiu, Jingru Lin, Xiaofei Huang, Bin Yang, Weihui Lu, Weihui Lu, Zhenhua Dai, Zhenhua Dai

“…Further researches on SCO may help understand its in-depth mechanisms of action and pave the way for the development of novel drugs to prevent and treat various immune-mediated inflammatory disorders as well as hepatic diseases, thereby significantly advancing its innovations and pharmaceutical applications.…”
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Interaction of norsecurinine-type monomeric and dimeric alkaloids with α-tubulin: a molecular docking study by Gérard Vergoten, Christian Bailly

“…The study contributes to a better understanding of the mechanism of action of Flueggea alkaloids and should help the design of anticancer analogues targeting the pironetin site of α-tubulin.…”
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Separate Aspects of Saving the Confidentiality of People Collaboration With Law Enforcement Bodies by V. M. Davydiuk

“…In the context of involving a confidant in accomplishing the tasks of criminal investigation, the author has offered to provide a separate, secret investigative (search) action, which, by analogy with the norm of the Art. 272 of the Criminal Procedural Code of Ukraine should be conducted according to the resolution of an investigator, agreed with the head of the pre-trial investigation agency, and the decision of a prosecutor.…”
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Activity-based chemical proteomics reveals caffeic acid ameliorates pentylenetetrazol-induced seizures by covalently targeting aconitate decarboxylase 1 by Guanjun Li, Ling Huang, Di Gu, Peili Wang, Letai Yi, Wenhua Kuang, Ying Zhang, Junzhe Zhang, Dandan Liu, Qiaoli Shi, Huan Tang, Jichao Sun, Guohua Zeng, Xin Peng, Jigang Wang

“…Conclusion In summary, this study elucidates, for the first time, the potential antiepileptic targets and mechanism of action of caffeic acid using the ABPP strategy. Our study provides evidence supporting the utilization of caffeic acid as a promising therapeutic agent for treating epilepsy and neuroinflammation-related disorders.…”
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A thorny pathway of macrophage activating factor (GcMAF): from bench to bedside by A. A. Ostanin, S. S. Kirikovich, E. V. Dolgova, А. S. Proskurina, E. R. Chernykh, S. S. Bogachev

“…DBP is converted to GcMAF as a result of site-specific selective deglycosylation under the action of β-galactosidase and sialidase, localized on activated B and T cells, respectively. …”
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A Modern Approach to Analyzing the Flowing Pressures of a Two-Phase CBM and Water Column in Producing Wellbores by Xinfu Liu, Chunhua Liu, Jianjun Wu

“…The flowing pressures of a two-phase column fully reflect the dynamic flowing performance due to the combined action of the water level, CBM, and water flow rates. …”
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Understanding Recruiters’ Acceptance of Artificial Intelligence: Insights from the Technology Acceptance Model by Filomena Almeida, Ana Junça Silva, Sara L. Lopes, Isabel Braz

“…The insights gathered from recruiters’ perspectives provide actionable recommendations for organizations seeking to leverage AI in recruitment processes. …”
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Neutrophil membrane biomimetic delivery system (Ptdser‐NM‐Lipo/Fer‐1) designed for targeting atherosclerosis therapy by Wei Li, Chang Liu, Sichuan Wang, Naifeng Liu

“…Inspired by the fact that neutrophils can be recruited to arterial plaques under the action of adhesion molecules and chemokines, the authors developed a neutrophil membrane hybrid liposome nano‐mimetic system (Ptdser‐NM‐Lipo/Fer‐1) that delivers Ferrostatin‐1 (Fer‐1) to the atherosclerotic plaque effectively, which is composed of Fer‐1‐loaded Ptdser‐modified liposomes core and neutrophils shell. …”
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Examining the Challenges of HIV Positive People With Disabilities in Accessing Medical Services in Rukungiri District: A Case Study of Nyakishenyi Sub-County by Atuheire, Fortunate

“…The study recommended that there is a need to adopt appropriate and disability-sensitive channels of communication to disseminate HIV/AIDS messages/information to the community of people with disabilities, there is a need to print HIV/AIDS posters with people with disabilities on them to attract the attention of the public and stir them into positive action and intervention and there should be promotion of adult literacy programs for people with disabilities to enable them to read, write and interpret disseminated HIV/AIDS messages.…”
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The Effect of Gender Inequality in Education on Rural Poverty: A Case Study of Nyakagyeme Sub-County Rukungiri District. by Akaruhanga, Jasper

“…There was a critical review of the issues that have been explored and studied both theoretically and empirically in the existing literature on gender inequality as an independent variable and education on rural poverty as the dependent variable and the methods of data collection were put into action. The research used 80 respondents as the sample size, and both qualitative and quantitative methods of data collection and analysis were employed. …”
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Supervision and Employee Performance: A Case Study of Lyamujungu SACCO Kabale District. by Atukunda, Emily

“…Lastly, the study revealed that there is a relationship between supervision and employee performance as supervision is an extremely vital part of a workplace, poor supervision leads to limited responsibility for taking action for the prevention of problems, mistakes, accidents, and injuries, poor supervision also opens the door for unethical behaviors within a company, effective supervision in workplaces acts as a motivating factor and increases job satisfaction, offering employee’s feedback on their work is an effective way of monitoring their progress, individual meetings between supervisors and their employees, poor supervision doesn’t only mean that there isn’t enough supervision, supervision entails overseeing the activities of the junior members to ensure that they are in line with an organization’s policies, supervision for subordinates increases employee productivity and overall performance. …”
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Impact of Pentecostal Churches in Social- Economic Transformation of Rural Areas in Kabale District. by Bakwengye, Deus

“…In chapter three this was where the methods of data collection were put into action. The research used both qualitative and quantitative methods of data collection and analysis. …”
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Pengaruh Pemberian Valsartan Dan Kurkumin Terhadap Pembentukan Fibrosis Di Tubulus Proksimal Ginjal Akibat Obstruksi Ureter Unilateral pada Tikus Wistar. by Lubis M, Alvarino Alvarino, Tofrizal Tofrizal, Erkadius Erkadius

“…Medicine is given use 1 cc spuit. Giving action in 14 days. The fifteenth day, we take renal of Wistar and do histology examination. …”
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RNA polymerase II-mediated rDNA transcription mediates rDNA copy number expansion in Drosophila. by George J Watase, Yukiko M Yamashita

“…Recently, we identified an rDNA-binding Zinc-finger protein Indra as a factor required for rDNA magnification, however, the underlying mechanism of action remains unknown. Here we show that Indra is a negative regulator of rDNA magnification, balancing the need of rDNA magnification and repression of dangerous DSBs. …”
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POLITICAL MECHANISM IN THE REALIZATION OF SUSTAINABLE DEVELOPMENT GOALS IN THE SYSTEM OF LOCAL GOVERNMENT by Микола БОГАЧЕНКО

“…Practically, the study offers actionable insights for policymakers and local governments to design strategies for sustainable local development. …”
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Pelletization of composted swine manure solid fraction with different organic co-formulates: effect of pellet physical properties on rotating spreader distribution patterns by Elio Romano, Massimo Brambilla, Carlo Bisaglia, Niccolò Pampuro, Ester Foppa Pedretti, Eugenio Cavallo

“…Results show that, as far as physical and chemical features are concerned, the greatest difference from the reference products used in this study is found in pellet size distribution after spreading since the disintegrating action of the rotating vanes does not affect the tested formulation with the same intensity as the commercial products. …”
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User-centred design of ChestCare: mHealth app for pulmonary rehabilitation for patients with COPD; a mixed-methods sequential approach by Suad J. Ghaben, Arimi Fitri Mat Ludin, Nazlena Mohamad Ali, Devinder Kaur Ajit Singh

“…Conclusions The development and validation of the ChestCare app resulted from conducting UCD iterative design and sequential MMR, which identified 13 functionalities, including symptom assessment, tracking lung volume, functional capacity test, action plan, intervention program, COPD education, COPD community, monitoring and reminders.…”
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Qinggan Yipi capsule ameliorates hepatic fibrosis in rats by down-regulating the TGF-β1/Smad2/3 signaling pathway and improving gut microbiota imbalance by Wenjing Xue, Haiqing Liu, Ziheng Su, Siqi Wang, Junping Cheng, Yunzhi Pan, Lurong Zhang

“…This study aims to clarify the anti-liver fibrosis effect of QgYp and its mechanism of action.MethodsThis study uses a carbon tetrachloride (CCl4) induced HF rat model and TGF-β1 stimulated HSC-T6 cell line (rat HSCs) as experimental models. …”
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Sustainable remediation of Cd-contaminated farmland through the rotation of rapeseed–rice varieties with different Cd accumulation potentials by Liang Wang, Qiqing Liu, Jingyi Fu, Yuxuan Xiao, Jun Yang, Xiaoyong Liao

“…Structural equation modeling revealed that with the combined action of crop rotation and variety selection the crop rotation directly reduced the soil available Cd or had an indirect effect by weakening the root-zone acidification effect and increasing soil Ava-P. …”
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