Focus on Depression in Parkinson’s Disease: A Delphi Consensus of Experts in Psychiatry, Neurology, and Geriatrics by Luis Agüera-Ortiz, Rocío García-Ramos, Francisco J. Grandas Pérez, Jorge López-Álvarez, José Manuel Montes Rodríguez, F. Javier Olazarán Rodríguez, Javier Olivera Pueyo, Carmelo Pelegrín Valero, Jesús Porta-Etessam

“…Efficacious and well-tolerated pharmacological options for Parkinson’s comorbid depression were selective serotonin reuptake inhibitors (especially sertraline), dual-action serotonin and norepinephrine reuptake inhibitors (venlafaxine, desvenlafaxine, and duloxetine), multimodal (vortioxetine, bupropion, mirtazapine, and tianeptine), and anti-Parkinsonian dopamine agonists (pramipexole, ropinirole, and rotigotine). …”
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Study of Component Composition and Antimicrobial Activity of the Ophthalmic Emulsion Based on the Safflower Flowers (Carthamus tinctorius L.) by Zhanar Abuova, Aknur Turgumbayeva, Ardak Jumagaziyeva, Kairolla Rakhimov, Aigul Jussupkaliyeva

“…The investigated emulsion-type eye drop shows bactericidal activity against S. aureus ATCC 6538-P, where the zone of growth suppression under the ophthalmic emulsion action corresponded to 9.0 ± 0.0 mm. The tested ophthalmic emulsion drops show the presumed biological activity against conditionally pathogenic bacteria. …”
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Case for hospital nurse-to-patient ratio legislation in Queensland, Australia, hospitals: an observational study by Carol Windsor, Patsy Yates, Linda H Aiken, Clint Douglas, Matthew D McHugh

“…The considerable variation across hospitals and the link with outcomes suggests that taking action to improve staffing levels was prudent.…”
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Cinnamic acid conjugated with triazole acetamides as anti-Alzheimer and anti-melanogenesis candidates: an in vitro and in silico study by Amir Shervin Shokouhi Asl, Mohammad Hosein Sayahi, Mohammad Hashem Hashempur, Cambyz Irajie, Amir Hossein Alaeddini, Seyedeh Niloufar Ghafouri, Milad Noori, Navid Dastyafteh, Javad Mottaghipisheh, Mehdi Asadi, Bagher Larijani, Mohammad Mahdavi, Aida Iraji

“…Furthermore, molecular docking and molecular dynamic studies of compound 10j were conducted to thoroughly evaluate its mode of action within the BChE active site.…”
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Mapping mad maps and recovery tools developed by mental health service users and survivors of psychiatry: a scoping review by Hernán María Sampietro, Viviana R Carmona, J Emilio Rojo, J Gómez-Benito

“…Of the 35 studies identified, 34 corresponded to applications of the Wellness Recovery Action Plan (WRAP). All of them, but one, evaluated group workshops implementations. …”
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Immune-related gene SOX10 affects ferroptosis in pancreatic cancer and facilitates tumor progression by targeting CMTM7-mediated Wnt/β-catenin signaling pathway by Guixing Jiang, Bicheng Wu, Kaikai Wang, Xiaofan Pu, Senhao Zhou, Xin Zhong, Xiaolong Liu, Suihan Wang, Tianyu Lin

“…After knocking down SOX10 using lentiviral transfection, SOX10 action on Wnt/β-catenin pathway and ferroptosis, as well as its anti-tumor activity in tumor-bearing mice were explored. …”
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The influence of the European Union on combating irregular migration in the Republic of Serbia by Cvetković Nenad, Obradović Zoran

“…For the past 15 years, the European Union has influenced Serbia to adopt several strategic documents and action plans for the first time to conduct work related to migration, border control, and human trafficking. …”
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Identification and analysis of individuals who deviate from their genetically-predicted phenotype. by Gareth Hawkes, Loic Yengo, Sailaja Vedantam, Eirini Marouli, Robin N Beaumont, GIANT Consortium, Jessica Tyrrell, Michael N Weedon, Joel Hirschhorn, Timothy M Frayling, Andrew R Wood

“…We classified 156 (0.12%) individuals as misaligned to their genetically predicted LDL-C and show that these individuals were enriched for both clinically actionable cardiovascular risk factors and rare genetic variants in genes previously shown to be involved in metabolic processes. …”
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Suberoylanilide Hydroxamic Acid Attenuates Autoimmune Arthritis by Suppressing Th17 Cells through NR1D1 Inhibition by Da Som Kim, Hong-Ki Min, Eun Kyung Kim, Seung Cheon Yang, Hyun Sik Na, Seon-Yeong Lee, Jeong-Won Choi, Kyung-Ah Jung, Seung-Ki Kwok, Sung-Hwan Park, Mi-La Cho

“…This study was performed to examine whether SAHA has therapeutic potential in an animal model of RA and to investigate its mechanism of action. Collagen-induced arthritis (CIA) mice were orally administered SAHA daily for 8 weeks and examined for their arthritis score and incidence of arthritis. …”
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Antibody-induced erythrophagocyte reprogramming of Kupffer cells prevents anti-CD40 cancer immunotherapy-associated liver toxicity by Florence Vallelian, Marc Pfefferlé, Irina L Dubach, Raphael M Buzzi, Elena Dürst, Nadja Schulthess-Lutz, Livio Baselgia, Kerstin Hansen, Larissa Imhof, Sandra Koernig, Didier Le Roy, Thierry Roger, Rok Humar, Dominik J Schaer

“…Repeated low-dose administration of a recombinant murine Ter119 antibody directed RBCs for selective phagocytosis in the liver and skewed the phenotype of liver macrophages into a Hmoxhigh/Marcohigh/MHCIIlow anti-inflammatory phenotype. This unique mode of action prevented necroinflammatory liver disease following high-dose administration of anti-CD40 mAbs. …”
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TGF-β3 Induces Autophagic Activity by Increasing ROS Generation in a NOX4-Dependent Pathway by Yun Zhang, Hong-Mei Tang, Chun-Feng Liu, Xie-Fang Yuan, Xiao-Yun Wang, Ning Ma, Guo-Feng Xu, Song-Ping Wang, Jun Deng, Xing Wang

“…Although it is well known that the relationship between ROS and autophagy is cell context-dependent, the exact mechanism of action remains unclear. The following study examined whether ROS act as upstream of autophagy activation in response to TGF-β3 induction. …”
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Association of ambient temperatures with suicide attempts and violence with the future projections under climate change scenarios: a nationwide time-stratified case-crossover study... by Jiwoo Park, Jieun Oh, Whanhee Lee, Yeonsu Kim, Jeong Ho Park, Ho Kim, Seungsik Hwang

“…Our findings might provide informative evidence for relevant action plans against climate change and intentional injuries.…”
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Psilocybin-assisted massed cognitive processing therapy for chronic posttraumatic stress disorder: Protocol for an open-label pilot feasibility trial. by Shakila Meshkat, Richard J Zeifman, Kathleen Stewart, Reinhard Janssen-Aguilar, Wendy Lou, Rakesh Jetly, Candice M Monson, Venkat Bhat

“…Preliminary evidence supports the potential therapeutic action of psilocybin to alleviate PTSD symptoms. This open-label pilot study aims to evaluate the feasibility, tolerability, and preliminary efficacy of a single dose 25 mg psilocybin in combination with one week of massed CPT in patients with chronic PTSD.…”
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Advanced Technologies from and Through a Prototype Radio Lesson with Budding Journalists: The Views and Attitudes of Xers, Millennials, and Zoomers by Constantinos Nicolaou

“…The survey’s research data were collected after six interactive teachings from and through advanced technologies, via a specially designed written questionnaire, as case study experiments that applied qualitative action research with quasi-experiments. Analysis, descriptive, and inductive statistics were then applied to them from and through Internet applications and services. …”
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Evaluating News In Press About Konya In Context Of City Image by Nur Görkemli, Başak Solmaz

“…With all these potentials, Turkish Ministry of Culture and Tourism chose Konya to be a branded city in its 2023 action plan. For branding activities, understanding city image has a crucial role. …”
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Typical and Local Diagnostic Reference Levels for Chest and Abdomen Radiography Examinations in Dubai Health Sector by Entesar Z. Dalah, Maitha M. Al Zarooni, Faryal Y. Binismail, Hashim A. Beevi, Mohammed Siraj, Subrahmanian Pottybindu

“…The present work aims to establish a comprehensive projection and weight-based structured DRL system that allows one to confidently highlight healthcare centers in need of urgent action. The data of a total of 5474 adult males and non-pregnant females who underwent chest and abdomen radiography examinations in five different healthcare centers were collected and retrospectively analyzed. …”
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Research on the Effect of MT+FES Training on Sensorimotor Cortex by Yuan-xing Wang, Zhi-zeng Luo

“…Both groups were trained at a fixed time at 9 : 00 am every day, each time lasting 20 minutes, once a day, 5 days a week, continuous training for 4 weeks, and the training action was elbow flexion training. During the training of the elbow flexion exercise, the experimental group applied FES with a frequency of 30 Hz, a pulse width of 100 μs, and a current of 10 mA to the muscles corresponding to the elbow flexion exercise, and rested for 10 s after 10-s stimulation. …”
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A deep contrastive learning-based image retrieval system for automatic detection of infectious cattle diseases by Veerayuth Kittichai, Morakot Kaewthamasorn, Apinya Arnuphaprasert, Rangsan Jomtarak, Kaung Myat Naing, Teerawat Tongloy, Santhad Chuwongin, Siridech Boonsang

“…Alternatively, algorithms could support local employees in tracking disease transmission and quick action, especially in Thailand where this cattle disease is common. …”
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Measuring Transducer for Air Gap Capacitive Sensor in Hydrogenerator by A. S. Levytskyi, I. O. Zaitsev, V. O. Bereznychenko, O. E. Sukhorukova

“…Commercially available meters with capacitive sensors, by their certain characteristics, are not always suitable for use on HGs.A secondary measuring transducer with improved characteristics is proposed for a capacitive gap sensor formed by coplanar parallel electrodes.The converter is developed on the basis of a balanced compensation bridge measuring circuit. The control action in the device is formed by the phase of the unbalancing signal.The structural diagram of the converter is presented and the algorithm of its operation is described. …”
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Comparative Analysis of Financial Flows in the Healthcare Systems of Germany, Austria and Czechia: Opportunities for Savings and Assessing the Tax-Like Nature of Health Insurance C... by Mini, Patrick

“…Its findings provide actionable insights for policymakers aiming to balance equity and efficiency in healthcare financing while ensuring public trust and sustainability. …”
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